Chemistry is the called the central science because it not only impacts virtually all fields of science and technology but also because it is a central contributor to the modern life that society enjoys. The PhD Program in Chemistry at the City University of New York (CUNY) provides students with a strong foundation in all areas of chemistry: analytical, biological, inorganic, materials, nano, organic, polymer, and physical.

Chemistry

Research Areas

• Analytical Chemistry • Inorganic Chemistry • Organometallic Chemistry • Biochemistry • Materials Chemistry • Polymer Chemistry • Biophysics • Medicinal Chemistry • Photochemistry • Chemical Biology • Nanoscience • Physical Chemistry • Computational Chemistry • Organic Chemistry • Radiochemistry

CUNY  Chemistry        •  Diverse  faculty        •  100+  faculty  mentors        •  250  papers  per  year    Interdisciplinary  efforts        •  Molecular  biophysics        •  Radiochemistry        •  Nanotechnology        •  Photonics        •  Medicinal  chemistry  

CUNY prides itself on the diversity of its faculty and students. Each student choses a research mentor from over 100 members of the CUNY doctoral faculty in Chemistry. These mentors are distributed among seven CUNY campuses and the CUNY Advanced Science Research Center that fosters interdisciplinary interactions. A flexible curriculum allows each student to personalize the coursework to their specific needs. Additional training in professionalism, safety, pedagogy, and career opportunities are provided to ensure your career success.

All students admitted to the PhD Program in Chemistry are awarded a CUNY Science Scholarship. This five-year award allows our student to concentrate on their research. CUNY Science Scholars spend the first year at the CUNY Graduate Center taking courses and learning about the research opportunities available to them. There is no teaching in year one. Students select a mentor and move to their mentors campus by the end of year one.

CUNY Science Scholars

Student comments The   chemistry   Ph.D  program  at   CUNY  has   allowed  me   to   pursue  my   interest.   I   have   greatly  benefited  from  my  experience  with  my  mentor,  professors  and  fellow  students.  

     Zhantong Mao (PhD 2015)   CUNY   is   dense   with   fantasLc   faculty,   administrators   and   fellow   students   that   collecLvely  engender  a  strong  likelihood  of  success.  

       Douglas Achan (PhD 2015)

CUNY Science Scholarship • five year support package • competitive stipend • low-cost health insurance • tuition remission

Years 2-5 are spent at a CUNY campus focused on their dissertation research and perhaps teaching.

CUNY offers s tudents the opportunity to do cutting-edge chemical research in a supportive program that has the feel of a small college while living in one of the world’s most dynamic cities. The PhD Program in Chemistry is unique amongst its peers in that it is a consor t ium of seven campuses throughout New York City. While all student receive their degree from the CUNY Graduate Center, they do their research at one of the CUNY colleges or the Advanced Science Research Center.

World-Class Science + Intimate Setting

Research Centers The   jewel   in  the  crown  of  CUNY’s  mulL-­‐billion  dollar   investment   in   interdisciplinary  scienLfic  research   is   the   CUNY   Advanced   Science   Research   Center   (hTp://asrc.cuny.edu).     Brimming  with   state-­‐of-­‐the-­‐art   instrumentaLon   and   experLse   in   nanoscience,   structural   biology,  photonics,   environmental   science,   and   neuroscience,   it   is   open   to   all   CUNY   students   and  faculty.     This   collaboraLve   resource   augments   the   resources   and   instrumentaLon   found   on  each   of   the   CUNY   campuses.     In   addiLon,   students   further   their   research   efforts   using   the  CUNY  High  Performance  CompuLng  Center  (hTp://www.csi.cuny.edu/cunyhpc/).

Participating Colleges • Brooklyn College • City College of New York • College of Staten Island • Hunter College • Lehman College • Queens College • York College

The diverse research opportunities offered by CUNY are augmented by the offerings of New York City. CUNY students participate in events hosted by the New York Academy of Sciences, the New York Local Section of the ACS, and the New York Hall of Science.

Daniel L. Akins, Ph.D. Professor & Chair of Chemistry and Biochemistry The City College Marshak Science Building 160 Convent Avenue New York, NY 10031 akins@ccny.cuny.edu www.sci.ccny.cuny.edu/~akins

Publications "High-Yield Photolytic Generation of Brominated Single-walled Carbon Nanotubes and their Application for Gas Sensing," Deon Hines, Mark Rümmeli, David Adebimpe and Daniel L. Akins, Chem. Commun., 50, 11568-11571 (2014). "Controllable modification of electronic Structure of Carbon-Supported Core–Shell Cu@Pd Catalysts for formic acid oxidation," Ren, Mingjun; Zhou, Yi; Tao, Feifei; Zou, Zhiqing; Akins, Daniel; Yang, Hui, J. Phys. Chem. C 118, 12669−12675 (2014). "Enhanced Raman Scattering by Molecular Nanoaggregates (Invited Review Article)," Daniel L. Akins, Nanomater Nanotechnol, 2014, 4:4. "Highly alloyed PtRu black electrocatalysts for methanol oxidation prepared using magnesia nanoparticles as sacrif icial templates," Liangliang Zou, Jing Guo, Juanying Liu, Zhiqing Zou, Daniel L. Akins and Hui Yang, Journal of Power Sources, 248, 356-362 (2014). "Vibrational and electronical properties of functionalized single-walled carbon nanotubes and double-walled boron nitride nanotubes," M. Aydin and D. L. Akins in Physical and Chemical Properties of Carbon Nanotubes. Edited by: Satoru Suzuki. ISBN 978-953-51-1002-6; Published 2013-02-27.

Dr. Akins has been a Professor of Chemistry at The City College of New York since 1981, and director of the C U N Y- C e n t e r f o r Analysis of Structure and Interfaces since 1988.

2014- current Professor & Chair, Department of Chemistry and Biochemistry.

1988-2015 Director, CUNY–Center for Analysis of Structures and Interfaces (CASI).

1981-2015 Professor of Physical Chemistry. 1979-1981 Senior Scientist, Polaroid Corp. 1968-1969 Postdoc: Institute of Molecular

Biophysics, The Florida State University.

1968 Ph.D.: University of California, Berkeley

Dr. Daniel L. Akins

Research Interests Keywords: Syntheses of semiconductor and magnetic oxide nanoparticles and nanorods; spectroscopic and dynamical investigations of spontaneous and nonlinear laser Raman scattering by monomeric and aggregated molecules on surfaces; excited state dynamics and determination of photophysical parameters for cyanine dyes and donor-acceptor Systems; quantum chemical calculations of porphyrins and dye molecules.

Mark R. Biscoe Assistant Professor of Chemistry The City College of New York 160 Convent Ave. New York, NY 10031 mbiscoe@ccny.cuny.edu http://www.sci.ccny.cuny.edu/~mbiscoe/index.html

Publications Li, L.; Zhao, S.; Joshi-Pangu, A.; Diane, M.; Biscoe, M. R. J. Am. Chem. Soc. 2014, 136, 14027-14030. Li, L; Wang, C.-Y.; Huang, R.; Biscoe, M. R. Nature Chem. 2013, 5, 607-612. Joshi-Pangu, A.; Biscoe, M. R. Synlett 2012, 23, 1103-1107. Joshi-Pangu, A.; Ma, X.; Diane, M.; Iqbal, S.; Kribs, R.; Huang, R.; Wang, C.-Y.; Biscoe, M. R. J. Org. Chem. 2012, 77, 6629-6633. Joshi-Pangu, A.; Wang, C.-Y.; Biscoe, M. R. J. Am. Chem. Soc. 2011, 133, 8478-8481. Joshi-Pangu, A.; Ganesh, M.; Biscoe, M. R. Org. Lett. 2011, 13, 1218-1221.

Research Interests Keywords: Transition metal catalysis, Organic synthesis, Asymmetric synthesis Broadly, research in the Biscoe group focuses on catalysis. The two major types of catalysis in which we are interested are transition metal catalysis and macromolecular catalysis. Our primary goals involve the development of practical and reliable processes for the construction of C–C and C–X (X = heteroatom) bonds. We are particularly interested in the development of new processes for the formation of common structural motifs of importance in medicinal chemistry and drug discovery.

Prof. Biscoe is an organic/organometal l ic chemist i n t e r e s t e d i n t h e d e v e l o p m e n t o f n e w reaction methodologies for a p p l i c a t i o n i n d r u g discovery.

2009- current Professor, City College of New York 2005-2008 NIH Postdoctoral Fellow, MIT 2000-2005 PhD, Columbia University

Dr. Mark R. Biscoe

Zimei Bu Associate Professor The City College of New York 160 Convent Avenue New York, NY 10031 zbu@ccny.cuny.edu http://www.sci.ccny.cuny.edu/~zbu/

Publications Phosphatidylinositol 4,5-Bisphosphate Clusters the Cell Adhesion Molecule CD44 and Assembles a Specific CD44-Ezrin Heterocomplex, as Revealed by Small Angle Neutron Scattering., Chen X, Ali Khajeh J, Ju JH, Gupta YK, Stanley CB, Do C, Heller WT, Aggarwal AK, Callaway DJ, Bu Z, J Biol Chem. 2015; 290(10):6639-52. Molecular conformation of the full-length tumor suppressor NF2/Merlin - a small angle neutron scattering study. Ali Khajeh, J., Ju, J., Atchiba, M., Allaire,M., Stanley, C., Heller, W.T., Callaway, D.J., Bu, Z., J Mol Biol. 2014 Jul 29;426(15):2755-68. Ligand-induced dynamic changes in extended PDZ domains from NHERF1., Bhattacharya S, Ju JH, Orlova N, Khajeh JA, Cowburn D, Bu Z., J Mol Biol. 2013 Jul 24;425(14):2509-28. Open Con fo rma t i on o f Ez r i n Bound to Phosphatidylinositol 4,5-Bisphosphate and to F-actin Revealed by Neutron Scattering, Jayasundar JJ, Ju JH, He L, Liu D, Meilleur F, Zhao J, Callaway DJ, Bu Z., J. Bio. Chem. 287:37119-33, 2012 Activation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopy. Farago, B., Li, J., Cornilescu, G., Callaway, D.J.E., Bu, Z., Biophys J. 99:3473-82, 2010 Research Interests

Keywords: Cell signaling, cell adhesion, intracellular trafficking of membrane receptors, neutron scattering, protein dynamics Research Projects include: 1.  Structure, dynamics, and assembly of transmembrane cell adhesion molecules and receptors; 2.  Protein-lipid interactions; 3.  How intracellular adapter proteins influence the trafficking, assembly and function of transmembrane

receptors; 4.  Small angle X-ray and neutron scattering; 5.  Quasielastic neutron scattering, neutron spin echo spectroscopy.

is a molecular biophysicist at City College

Dr. Zimei Bu

Research Interests Keywords: Actinides, f-block, Lanthanides, Luminescence, Mentoring relationships, Metal oxides, Nuclear fuel cycle, Radiochemistry, Redox chemistry

His research can be broadly defined as the fundamental chemistry of f-block and group VII metals. There are presently two major research aims associated with this theme: 1.  To develop the use of luminescence as a tool to understand the chemical speciation of lanthanides

and actinides in the environment, terrestrially and extra-terrestrially. 2.  To use soluble metal oxides (polyoxometalates) to fundamentally understand how actinide ions

interact with minerals at a molecular level.

He also studies the mentoring relationship and is working towards codifying co- and multi-mentorship models in interdisciplinary research settings.

Dr. Benjamin P. Burton-Pye Assistant Professor Lehman College Department of Chemistry 250 Bedford Park Blvd West Bronx, NY Benjamin.Burtonpye@lehman.cuny.edu

Publications M. Deri, S. Ponnala, P. Kozlowski, B.P. Burton-Pye, H. Cicek, C. Hu, J.S. Lewis, L.C. Francesconi, p-SCN-BN-HOPO: A Superior Bifunctional Chelator for Zr ImmunoPET. Bioconj. Chem. 2015, DOI:10.1021/acs.bioconjchem.5b00572 F. Poineau, K.E. German, B.P. Burton-Pye, P.F. Weck, E. Kim, O. Kriyzhovets, A. Safonov, V. Ilin, L.C. Francesconi, A.P. Sattelberger, K.R. Czerwinski, Speciation of Technetium Peroxo Complexes in Sulfuric Acid Revisited. J. Rad. Anal. Nucl. Chem. 2015 , 303(2) , 1163-1167. DOI : 10 .1007/s10967-014-3434-1 M.K. Bera, R.J. Ellis, B.P. Burton-Pye and M.R. Antonio, Structural Aspects of Heteropolyacid Microemulsions, Phys. Chem. Chem. Phys., 2014, 6, 22566-22574. DOI: 10.1039/c4cp03014a D. McGregor, B.P. Burton-Pye, W. W. Lukens, and L.C. Francesconi, Insights into stabilization of the 99TcVO core for synthesis of 99TcVO compounds. Eur. J. Inorg. Chem., 2014, 6, 1082-1089. DOI: 10.1002/ejic.201301034

F. Poineau, B.P. Burton-Pye, A. Maruk, G. Kirakosyan, I. Denden, D.B. Rego, E.V. Johnston, A.P. Sattelberger, M. Fattahi, L.C. Francesconi, K.E. German and K.R. Czerwinski, On the Nature of Heptavalent Technetium in Concentrated Nitric and Perchloric Acid, Inorg. Chimica Acta, 2013, 398, 147-150. DOI:10.1016/j.ica.2012.12.028

B e n j a m i n B u r t o n - P y e specializes in the fundamental chemistry of elements found within the nuclear fuel cycle. His research focuses on manipulating the coordination environment around these metal ions and how that affects c h e m i c a l , r e d o x a n d photophysical properties.

2015-Present Assistant Professor, Lehman College 2013-2015 Radiochemistry Research Scientist,

Hunter College 2010-2013 Research Associate, Hunter College 2005-2010 Postdoc, Hunter College 2004-2005 Postdoc, U of Manchester, UK 2001-2004 PhD, U of Manchester, UK

Dr Benjamin P. Burton-Pye

Elise Champeil Associate Professor John Jay College of Criminal Justice 524 west 59th street New York, NY10019 echampeil@jjay.cuny.edu http://www.jjay.cuny.edu/faculty/elise-champeil

Publications Champeil E., Sapse A.M “Synthesis of a Mitomycin C-Lexitropsin Hybrid”. Comptes rendus des Séances de l’Académie Francaise, 17, 2014 1190. Champeil E., Paz M., Lukasiewicz E., Kong W., Watson S., Sapse A.M.“Synthesis of a major m i t o m y c i n C D N A a d d u c t v i a a triaminomitosene”. Bioorganic and Medicinal Chemistry Letters, 22, 2012 7198. Lesar C.T., Decatur J., Luckasiewicz E., Champeil E.“ Identi f icat ion of Gamma-Hydroxybutyric acid (GHB) and Gamma-Butyrolactone (GBL) in beverages using NMR and the PURGE so lven t -suppress ion technique”. Forensic Science International,212, 2011 40. Weng M-W, Zheng Y., Jasti V.P., Champeil E., Tomasz M., Wang Y., Basu A.K., Tang M.-S. “Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model”, Nucleic Acid Research, 38, 2010 6976. Liu J., Proni G., Champeil E. “Identification and quant i ta t ion o f 3 ,4-methy lened ioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by 1H NMR spectroscopy. Application to five cases of intoxication”, Forensic Science International, 194, 2010 103.

Research Interests Synthesis of Mitomycin C and Decarbamoyl mitomycin C DNA adducts: Our aim is to synthesize DNA interstrand crosslinks generated by decarbamoyl mitomycin C (DMC) and mitomycin C (MC) (MC α-ICL and DMC β-ICLs). In addition, the role of p21 in the upstream p53-independent signaling pathway in response to these crosslinks is examined. Analysis of drugs (recreational and medicinal) in bio fluids using NMR spectroscopy.

Prof. Champeil is a synthetic chemist interested in the DNA alkylating drug Mitomycin C (MC). She synthesized MC-DNA Interstrand crosslinks to determine how the local structure of these adducts is responsible for the different b i o c h e m i c a l r e s p o n s e s produced by cancer cells upon treatment.

2014- 2010 Current position 2006-2010 Assistant professor (John Jay College) 2003-2006 Postdoc (CUNY) 2002 PhD, Trinity College, Ireland

Dr. Elise Champeil

Publications Fernández-Gallardo, J. et al. Versatile Synthesis of Cationic N-Heterocyclic Carbene-Gold(I) Complexes Containing a Second Ancillary Ligand. Design of Heterobimetallic Ruthenium-Gold Anticancer Agents’. Chem. Commun. 2016, 52, 3155-3158. Contel, M. et al. Titanocene Gold Derivatives Comprising Thiolato Ligands. US Patent 20,150,353,591 (2016). F r i k , M . e t a l . ‘ C y c l o m e t a l a t e d Iminophosphorane Gold(III) and Platinum (II) Complexes. A Highly Permeable cationic Platinum (II) Compound with Promising Anticancer Properties’. J. Med. Chem. 2015, 58, 5825-5841. Fernández-Gallardo, J. et al. ‘Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro an in vivo.’ Chem. Sci. 2015, 6, 5269-5283. Frik, M. et al. In vitro and in vivo Evaluation of Water-soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer. J. Med. Chem. 2014, 57, 9995–10012.  

Research Interests Keywords: Organometallic, Cancer, Antimicrobial, Gold Catalysis, Water-soluble, C-C and C-Heteroatom Bond formation Our group is focused on the synthesis of metallodrugs as anticancer and antimicrobial agents with a special interest on heterometallic gold-based compounds. We study the biological activity and possible mode of action of the compounds (in our own cell culture room). We use gold derivatives in homogeneous catalysis and we study the possible mechanism of these catalysts by using different techniques.

M a r i a C o n t e l i s a n inorganic/organometall ic synthetic chemist. Her main interests lie on the rational design of metallodrugs and homogeneous catalysts.

2011- current Associate Professor Brooklyn College 2006-2010 Assistant Professor Brooklyn College 2001-2006 Senior Researcher CSIC-University of

Zaragoza, Spain 1999-2000 Postdoc University of Utrecht, Holland 1997-1999 Postdoc Australian National University, Australia 1993-1996 PhD Public University of Navarra, Spain

Dr. Maria Contel

Maria Contel Associate Professor Brooklyn College 2900 Bedford Avenue Brooklyn, NY mariacontel@broklyn.cuny.edu http://userhome.brooklyn.cuny.edu/mariacontel/

Ruel Z. B. Desamero Associate Professor York College, the Institute of Macromolecular Assembly, and the Graduate Center 94-20 Guy R. Brewer Blvd. Jamaica, NY 11451 rdesamero@york.cuny.edu www.cuny.edu/xxxx

Publications A. Mojica, E., J. Vedad, and R.Z.B. Desamero (2015) “Vibrational Analysis of α-Cyanohydroxycinnamic acid” Journal of Molecular Structure (in press). B. Profit, A.A., J. Vedad, M. Saleh and R.Z.B. Desamero (2015) “Aromaticity and Amyloid Formation: Effect of π-Electron Distribution and Aryl Substituent Geometry on the Self-Assembly of Peptides Derived from hIAPP22-29 “ Archives of Biochemistry and Biophysics 567: 46-58. C. Nie, B., H. Deng, R.Z.B. Desamero and R. Callender (2013) “Large Scale Dynamics of the Michaelis Complex in Bacillus stearothermophilus Lactate Dehydrogenase Revealed by Single Tryptophan Mutants Study” Biochemistry 52: 1886-1892. D. Profit, A.A., V. Felsen, J. Chinwong, E.-R. Mojica, and R.Z.B. Desamero (2013) “Evidence of π-stacking Interactions in the Self-assembly of hIAPP22-29” PROTEINS: Structure, Function and Bioinformatics 81: 690-703. E. Deng, H., D.V. Vu, K. Clinch, R. Desamero, R.B. Dryer and R. Callender (2011) “Conformational Heterogeneity Within the Michaelis Complex of Lactate Dehydrogenase” Journal of Physical Chemistry B 115: 7670-7678.

Research Interests Keywords: vibrational spectroscopy; fluorescence; circular dichroism; temperature-jump techniques; structural biology; protein biochemistry; enzymology My research is centered on investigating the structural and dynamical aspects of protein-small molecule interactions using techniques such as vibrational spectroscopy and temperature-jump relaxation. One aspect of the work is to understand at the molecular level how protein systems work. Enzyme-substrate interactions have long been recognized as representing an extreme expression of structural complementarities in biological chemistry. Basic research geared towards understanding the inner workings of an enzyme system is important if cures for the diseases caused by a malfunctioning or deficient enzyme are to be found. We have also started investigating the mechanism behind amyloid formation with the goal of synthesizing peptide inhibitors that diminish protein aggregation.

D r . D e s a m e r o i s a spectroscopist by training cur rent ly invest iga t ing protein-ligand interaction as well as protein-protein aggregation using various techniques.

2010 - current Associate Professor, York College - CUNY 2003 - 2010 Assistant Professor, York College - CUNY 2000 - 2002 Postdoc, Albert Einstein College of Medicine 1998 - 2000 Postdoc, City College - CUNY 1998 PhD, University of Connecticut

Dr. Ruel Desamero

Amedee des Georges Assistant Professor, ASRC Structural Biology Initiative City College, Dept. of Chemistry and Biochemistry CUNY Advanced Science Center, Room 3.316 85 St. Nicholas Terrace New York NY 10031 Amedee.desGeorges@asrc.cuny.edu structbio.asrc.cuny.edu

Publications R. Zalk, O. B. Clarke, A. des Georges et al., Structure of a mammalian ryanodine receptor. Nature, 2014 A. des Georges et al., Structure of mammalian eIF3 in the context of the 43S preinitiation complex, Nature, 2015 Y. Hashem, A. des Georges et al., Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29. Cell, 2013, 153, 1108-1119. A. des Georges et al., Structure of the mammalian ribosomal pre-termination complex associated with eRF1• eRF3• GDPNP, Nucleic acids research, 2013, gkt1279. Y. Hashem, A. des Georges et al., High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome. Nature, 2013, 494(7437), 385-389.

Research Interests Keywords: Cell regulation • Cancer • Heart diseases • Biochemistry • Molecular biology • Structural biology • Cryo-electron microscopy • Image analysis • Modeling • Methods development • Translation initiation • Membrane proteins • Calcium signaling

The des Georges lab is interested in the molecular m e c h a n i s m s o f c e l l regulation. We use cryo-electron microscopy to decipher at the atomic level the func t ion o f la rge macromolecular complexes involved in calcium signaling and in the regulation of protein synthesis.

2015- current Assistant professor, Structural Biology Initiative, CUNY Advanced Science Research Center Assistant professor, Department of Chemistry and Biochemistry, City College of New York

2008-2015 Postdoc – HHMI / Columbia University – (w/ Dr. Joachim Frank) 2004-2008 PhD – MRC-Laboratory of Molecular Biology, Cambridge, UK – (w/ Drs. Linda Amos & Jan Lowe)

Dr. Amedee des Georges

Terry Dowd Associate Professor Brooklyn College 2847 Old Ingersoll 2900 Bedford Ave. Brooklyn, NY tdowd@Brooklyn.cuny.edu http://academic.brooklyn.cuny.edu/chem/howell/facultyWebPages/Dowd/Dowd_home.htm

Publications C h a n K L , D o w d T L , G i b n e y B R . , “Characterization of the Zn(II) binding properties of the human Wilms' tumor suppressor protein C-terminal zinc finger peptide.” (2014) Inorg Chem. 53:6309. Malashkevich, V., Dowd, T.L., "The X-ray Crystal Structure of Bovine 3 Glu-Osteocalcin.“ Biochemistry (2013) 52:8387. B. Kalmatsky, T.L. Dowd, “Structural studies of N-terminal mutants of connexin 32 using 1H NMR spectroscopy.” Arch. Biochem. Biophys. (2012) 526: 1-8. A.U. Monir, T.L. Dowd, “The Effect of Lead on Bone Mineral Properties From Female Adult C57/BL6 Mice.” Bone 2010 47:888-94. B. Kalmatsky, T.L. Dowd, “Structural studies of the N-terminus of Connexin 32 using 1H NMR spectroscopy.” Arch. Biochim. Biophys. 2009 490: 9-16.

Research Interests My research involves investigating the role of the bone protein osteocalcin in bone mineral diseases such as Pb2+ toxicity, low Mg2+ diets and diabetes. The research involves multiple techniques such as atomic absorption, FTIR Imaging and microCT to investigate alterations in mouse bone mineral properties. The second project involves NMR structural-functional studies of the gap junction molecule Connexin in health and diseases such as deafness, fatal skin disease and neuropathy. The project uses 2D NMR techniques on a high field magnet and electrophysiological techniques characterizing the mutant gap junction channels.

Dr. Terry Dowd is involved in two areas of research. One area is the alteration in bone mineral properties in disease. The second project involves al terat ions in s t r u c t u r e – f u n c t i o n relationships in the gap junction molecule Connexin in deafness, neuropathy and skin disease.

2014- current Associate Professor 2005 Assistant Professor 1992-1996 Instructor 1986-1992 Postdoc 1986 Ph.D.

Dr. Terry Dowd

Charles Michael Drain Professor Hunter College & Rockefeller University Department of Chemistry 695 Park Avenue New York NY cdrain@hunter.cuny.edu www.hunter.cuny.edu/chemistry/mike/drain

Publications T. M. Shaffer, M. A. Wall, S. Harmsen, V. A. Longo, C. M. Drain, M. F. Kircher, J. Grimm, Nano Letters 2015, 15, 864-868. "Silica Nanoparticles as Substrates for Chelator-free Labeling of Oxophilic Radioisotopes" S. Singh, A. Aggarwal, N. V. S. D. K. Bhupathiraju, B. Newton, A. Nafees, R. Gao, C. M. Drain, Tet. Let. 2014, 55, 6311-6314. "Synthesis and cell phototoxicity of a triply bridged fused diporphyrin appended with six thioglucose units" A. Aggarwal, S. Thompson, S. Singh, B. Newton, A. Moore, R. Gao, X. Gu, S. Mukherjee, C.M. Drain. Photochem. Photobiol. 2014, 90, 419–430. “Photophysics of Glycosylated Derivatives of a Chlorin, Isobacteriochlorin and Bacteriochlorin for Photodynamic Theragnostics: Discovery of a Two-photon-absorbing Photosensitizer” M. Jurow, A. Varotto, V. Manichev, N. A. Travlou, D. A. Giannakoudakis, C. M. Drain, RSC Adv. 2013, 3, 21360–21364, “Self-organized nanostructured materials of alkylated phthalocyanines and underivitized C60 on ITO” M. Jurow, V. Manichev, C. Pabon, B. Hageman, Y. Matolina, C. M. Drain Inorg. Chem. 2013, 52, 10576-10582. “Self-Organization of Zr(IV) Porphyrinoids on Graphene Oxide Surfaces by Axial Metal Coordination” Research Interests

Keywords: porphyrins, photophysics, phototherapy, nanotechnology, supramolecular Bottom-up self-organization of functional photonic materials composed of porphyrinoid dyes allows fabrication of next generation sensors, solar energy harvesting, and biomedical devices. Click-chemistry makes the dye commercially viable, and the fundamental photophysical properties of these materials guides development of more efficient dyes. (2) Porphyrinoid dyes are being developed as theranostics (the same compound is used for both therapy and diagnostic) for photodynamic therapy of diseases such as cancer. (3) Biomedical applications of nanoparticles composed of organic and inorganic materials, including radiolabled materials, for imaging and therapy are being developed in collaboration with Researchers at Memorial Sloan Kettering and Rockefeller University.

CM Drain is chair of the Department of Chemistry at H u n t e r C o l l e g e w i t h research in supramolecular materials, photonics, photo-therapeutics, and medical photo-diagnostics

1996- present Professor, Hunter College CUNY 1990- present Adj. Faculty, Rockefeller University 1990-1993 Postdoc, Univ. of Strasburg, France 1984-1988 PhD, Tufts University

Dr. Charles Michael Drain

Dr Dorthe M. Eisele

Dr Dorthe M. Eisele Department of Chemistry, City College Center for Discovery and Innovation Advanced Science Research Center 85 Saint Nicolas Terrace, New York, NY 10031 eisele@ccny.cuny.edu http://eiselegroup.com/ www.cuny.edu/asrc

Selected Publications Eisele,  D.M.,  Arias,  D.H.,  Fu,  X.,  Bloemsma,  Steiner,  C.P.,  Jensen,  R.,  Rebentrost,  P.,  Eisele,  H.,  Llyod,  S.,  Tokmakoff,  A.,  Knoester,  J.,  Nicastro,  D.,  Nelson,  K.A.,  &  Bawendi,  M.G.  “Robust  Excitons  in  So/  Supramolecular  Nanotubes.”  PNAS  111  (2014)  E3367-­‐E3375. Eisele,  D.M.,  Cone,  C.W.,  Bloemsma,  E.A.,  Vlaming,  C.G.F.  van  der  Kwaak,  S.M.,  Silbey,  R.J.,  Bawendi,  M.G.,  Knoester,  J.,  Rabe,  J.P.,  and  Vanden  Bout,  D.A.  “U:lizing  Redox-­‐Chemistry  to  Elucidate  the  Nature  of  Exciton  Transi:ons  in  Supramolecular  Dye  Nanotubes.”  Nature  Chem.  4  (2012)  655–662.    Eisele,  D.M.,  v.  Berlepsch,  H.,  BöTcher,  C.,  Stevenson,  K.J.,  Vanden  Bout,  D.A.,  Kirstein,  S.,  and  Rabe,  J.P.  “Photoinduced  growth  of  sub-­‐7  nm  silver  nanowires  within  a  chemically  ac:ve  organic  nano:bular  template.”  JACS  132,  (2010)  2104-­‐2105.   Eisele,  D.M.,  Knoester,  J.,  Kirstein,  S.,  Rabe,  J.P.,  and  Vanden  Bout,  D.A.  “Uniform  exciton  fluorescence  from  individual  molecular  nanotubes  immobilized  on  solid  Substrates.”  Nature  Nanotech.  4  (2009)  658-­‐663.

Research Interests Keywords: New materials & design principles for solar energy systems; Artificial and biological model systems for light-harvesting (LH) in order to better understand the fundamental processes that govern nature's highly efficient photosynthetic masterpieces; Collective phenomena found in self-assembled nanoscale systems such as supra-molecular assemblies (Frenkel exciton systems), semiconductor nanostructures (Wannier exciton systems), metallic nanostructures (plasmonic systems), and organic/inorganic hybrid systems; Energy and electron transport processes in nanoscale systems; steady-state and time-resolved spectroscopy combined with microscopy techniques.

Dorthe Eisele is a Professor of Chemistry at City College and a member of the Graduate Center. Her research interests are in materials research and nanoscience, with a focus on new materials and design principles for solar energy systems.

Current: Assistant Professor, Chemistry, City College of New York, Principal Investigator, CUNY Graduate Center (Chemistry).

Previously: Postdoctoral Associate,

Massachusetts Institute of Technology, Cambridge, USA

Dr.rer.nat (Ph.D. equivalent), Humboldt University of Berlin, Berlin, Germany

name Position: Professor of Chemistry and Biochemistry Affiliation: Queens College of CUNY Address: 65-30 Kissena Boulevard Flushing, NY 11367 Email: robert.engel@qc.cuny.edu

Publications  143. J.  Hatcher,  F.  Zavurov,  L.  BabukuTy,  

T.  strekas,  and  R.  Engel,  “PolycaLons.  XXII.  Ru(bpy)2L2  and  Ru(phen)2L2  Systems  with  CaLonic  4,4’-­‐Bipyridine  Ligands:  Syntheses,  CharacterisLcs,  and  InteracLons  with  DNA,”  Amer.  Chem.  Sci.  J.,  9,  1-­‐7  (2015),  ArLcle  no.ACSJ  19681.  

142. S.I.  Lall-­‐Ramnarine,  J.A  Mukhlall,  J.F.  Wishart,  R.R.  Engel,  A.R.  Romeo,  M.  Gohdo,  S.  RamaL,  M.  Berman,  and  S.  Suarez,  "Cyclic  Phosphonium  Ionic  Liquids,"  Beilstein  J.  Org,  Chem.,  10,  271-­‐275  (2014).  

141.  L.  BabukuTy,  E.  Moskovic,  D.  Wadler,  T.  Strekas,  and  R.  Engel,  "PolycaLons.  XX.  New  Monodentate  CaLonic  Ligands  and  Their  CoordinaLon  with  Ruthenium  for  the  ConstrucLon  of  Complexes  Expressing  Enhanced  InteracLon  with  DNA,"  Organic  Chemistry  Interna:onal,  ArLcle  ID  282137,  Volume  2012.    140.  R.  Engel,  "Glycoside  based  ionic  liquids,"  in  Ionic  Liquids,  Chapter  3,  S.  Handy,  ed.,  In-­‐Tech,  Rijeka,  CroaLa  (2011).      139.  R.  Engel,  I.  Ghani,  D.  Montenegro,  M.  Thomas,  B.  Klaritch-­‐Vrana,  A.  Castaño,  L.  Friedman,  J.  Leb,  L.  Rothman,  H.  Lee,  C.  Capodiferro,  D.  Ambinder,  E.  Cere,  C.  Awad,  F.  Sheikh,  J.  Rizzo,  L.-­‐M.  NesbiT,  E.  Testani,  and  K.  Melkonian,  "PolycaLonic  Glycosides,"  Molecules,  16,  1508-­‐1518  (2011).  

Research Interests Keywords: Polycationic organic salts, alternative antibacterial, antifungal, and antiviral systems, organophosphorus syntheses and mechanisms, antitumor agents.

We have been engaged for quite a few years in the p r e p a r a t i o n o f antimicrobial agents that avoid the problems of resistance associated with antibiotic materials. See http: / /www.qc.cuny.edu/Academics/Degrees/DMNS/P a g e s /ENGEL_Research_Interests.aspx

1968- current Current position: Professor of Chemistry and Biochemistry 1966-1968 Postdoc: US Army 1966 PhD: Penn State

Dr. Robert Engel

Stephen Philip Fearnley Associate Professor Department of Chemistry CUNY-York College 94-20 Guy R. Brewer Blvd. Jamaica NY 11451 sfearnley@gc.cuny.edu www.york.cuny.edu/portal_college/sfearnley  

Publications S. P. Fearnley* & P. M. Lory, "A concise synthesis of (±)-3-deoxyisoaltholactone”

Tetrahedron Lett., 2014 55, 5207-5209. S. P. Fearnley* & C. Thongsornkleeb, "Oxazolone Cycloadducts as Heterocyclic Scaffolds for Alkaloid Construction: Synthesis of (±)-2-epi-Pumiliotoxin C”

J. Org. Chem. 2010 75, 933-936. S. P. Fearnley* & P. M. Lory, "Intramolecular Vinylsilane–Oxocarbenium Condensations – Concise Assembly of cis-Bicyclic Ether Arrays”

Org. Lett. 2007 9, 3507-3510. S. P. Fearnley*, "2-(3H)-oxazolone – A Simple Heterocycle with Manifold Potential"

"Current Organic Chemistry; Volume 8, Asymmetric Synthesis" 2004 8, 1289-1338.

S. P. Fearnley* & M. W. Tidwell, "Cyclization of Aryl Silanes with Unexpected Retention of Silicon"

Org. Lett. 2002 4, 3797-3798. S. P. Fearnley* & E. Market, "Intramolecular Diels-Alder Reactions of N-Substituted Oxazolones”

Chem. Commun. 2002 438-439. Research Interests Keywords: Organic Synthesis • Organic Reactions • Natural Products

• Investigation & use of oxazolone as a useful heterocyclic scaffold for alkaloid synthesis - studies of intramolecular Diels-Alder reactions with oxazolone as dienophile.

• Novel organosilane chemistry for approaches to bioactive ethers - concise assembly of cis-fused bicyclic ether arrays via intramolecular attack of vinylsilanes at tethered oxocarbenium ions. A related silyl-activated Friedel-Krafts process requires an unusual combination of electronic & steric effects.

• Recently completed targets include 2-epi-pumiliotoxin C & deoxyaltholactone. Similar approaches to gephyrotoxin & dysiherbaine are underway.

As a synthetic organic chemis t , my research involves development of new methodology for the construction of bioactive natural products: alkaloids, cyclic ether arrays, & C-glycosides.

2003- current York College 1999-2003 Lamar University 1998-1999 Postdoc, Penn State: Mike Coleman 1995-1997 Postdoc, Penn State: Ray Funk 1992-1994 Postdoc, Virginia Tech: Tomas Hudlicky 1988-1992 Ph.D., University of Salford, U.K.

Dr Stephen Philip Fearnley

Harry D. Gafney Professor Queens College Department of Chemistry, 206 Remsen Hall 65-30 Kissena Blvd. Flushing, NY 11367 Email.harry.gafney@qc.cuny.edu www.cuny.edu/hgafney

Publications Gafney,  H.D.;  Jagassar,  P.;  Perri,  A.;  Ibarrola,  G.  “Ligand  IniLated  Self-­‐Assembly    of  Pt  and  Ir  NanoparLcles  about  Ru(II)  Diimines  in  Room  Temperature  Fluid  SoluLon” J.  Phys.  Chem.  C  (2013),  117(94),  1925-­‐1934.          Gafney,  H.D.;  Look  E.C.  “Photocatalyzed  Conversion  of  CO2  to  CH4:  An  Excited  State  Acid-­‐Base  Mechanism” J.  Phys.  Chem.  A  (2013),  117(47),  12268-­‐12279.        Gafney,  H.  D.,  Look,  E.  G.  Zaitsev,  V.;  Xu,  S.;  “Nature  and  DistribuLon  of  Tungsten  Oxides  in  Porous  Vycor  Glass” J.  Non-­‐Crystal.  Solids,  (2015),  409,  1-­‐7.      Selmani,  A.;  Spadina,  M.;  Plodinec,  M.;  Delač  Marion,  I.;  Willinger,  M.  G.;  Lützenkirchen,  J.;  Gafney,  H.D.;  Redel,  E.  “An  Experimental  and  TheoreLcal  Approach  to  Understanding  the  Surface  ProperLes  of  One-­‐Dimensional  TiO2  Nanomaterials” J.  Phys.  Chem.  C    (2015),  119,  19729-­‐19742.      J.  L.  Dominguez-­‐Juarez,  J.L.;  Moocarme,  M.;  Lempel,  A.;  Singh,  N.D.;    Zhang,  C.J.    Gafney,  H.D.;  Vuong,  L.T.  “Influence  of  Solvent  Polarity  on  Light-­‐Induced  Thermal  Cycles  in  Plasmonic  Nanofluids” Op:ca    (2015),  2,  447-­‐453.

Research Interests Keywords: Ru(II) Diimines, Transition Metal Oxides, Photocatalysis, Nanoporous Silica Matrices

Current research focuses on excited state electron-transfer and acid-base chemistry, photocatalysis of multi-electron, multi-proton conversions such as CO2 to CH4 and NOx to N2, synthesis of mixed valent metal oxides in nanoporous silica matrices, absorption and emission properties of tungsten and molybdenum oxides, ground and excited state acid-base properties of tungsten and molybdenum oxides.

Coordination Chemistry Photochemistry Photophysics Material Science Integrated Optics

1981- current Professor 1970-1973 Postdoc, Northwestern, USC 1970 PhD

Dr Harry D. Gafney

Emilio Gallicchio Assistant Professor Department of Chemistry, Brooklyn College 2900 Bedford Avenue Brooklyn, NY egallicchio@brooklyn.cuny.edu sites.google.com/site/emiliogallicchiolab

Publications Emilio Gallicchio, et al. BEDAM Binding Free Energy Predictions for the SAMPL4 Octa-Acid Host Challenge. J. Comp. Aided Mol. Des.  29, 315-325 (2015). Emilio Gallicchio, et al. Virtual Screening of Integrase Inhibitors by Large Scale Binding Free Energy Calculations: the SAMPL4 Challenge. J Comp Aided Mol Design, 28, 475-490 (2014). Guohua Yi, Mauro Lapelosa, Emilio Gallicchio, Gail Ferstandig Arnold et al. Chimeric Rhinoviruses Displaying MPER Epitopes Elicit Anti-HIV Neutralizing Responses. PLoS ONE 8(9), e72205 (2013). Gallicchio E. Role of Ligand Reorganization and Conformational Restraints on the Binding Free Energies of DAPY Non-Nucleoside Inhibitors to HIV Reverse Transcriptase. Computational Molecular Bioscience, 2, 7-22 (2012).

Research Interests - Thermodynamics of protein-protein and protein-ligand binding - Virtual drug screening -  Protein conformational equilibria - Statistical thermodynamics of protein folding and misfolding - Thermodynamics of solvation of biological macromolecules - Force field development and high resolution protein modeling - Design of high performance computational chemistry algorithms - Parallel and distributed computing

Emilio Gallicchio’s research is in the area of computational molecular biophysics. He uses advanced computational models to investigate the dynamics and thermodynamics of biological systems.

2013- current Asst. Professor, Dept. Chemistry, Brooklyn College 2012-2013 Research Professor, Dept. Chemistry, Rutgers University 2001-2012 Associate Director, BioMaPS Institute, Rutgers University 1997-2000 Postdoctoral, Rutgers University 1991-1996 PhD Columbia University, Chemical Physics

Dr. Emilio Gallicchio

Kevin H. Gardner Director, Structural Biology Initiative CUNY Advanced Science Center, Room 3.322 85 St. Nicholas Terrace New York, NY 10031 Kevin.Gardner@asrc.cuny.edu structbio.asrc.cuny.edu • kglab.org

Publications Y. Guo et al., Coiled-coil coactivators play a structural role mediating interactions in hypoxia inducible factor heterodimerization. J. Biol. Chem., 2015, online now. V. Ocasio et al., Ligand-induced folding of a two component signal ing receiver domain. Biochemistry, 54, 1353-1363. G. Rivera-Cancel et al., Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation, Proc. Natl. Acad. Sci USA, 2014, 111, 17839-17844. L.B. Motta-Mena et al., An optogenetic gene expression system with rapid activation and deactivation kinetics. Nat. Chem. Biol., 2014, 10, 196-202. T.H. Scheuermann et al., Allosteric inhibition of Hypoxia Inducible Factor 2 with small molecules. Nat. Chem. Biol., 9, 271-276.

Research Interests Keywords: environmental sensing • protein/protein interactions • ligand binding • allostery • NMR spectroscopy • X-ray diffraction • biochemistry • photosensors • cancer • protein engineering

The Gardner lab studies how cells perceive and respond to changes in the environment around them. Such information provides insights into fundamental p r i n c i p l e s o f p r o t e i n structure and signaling, guides the engineering of new protein-based tools, and lays the foundation for new therapeutic strategies.

2014- current Director, Structural Biology Initiative, CUNY Advanced Science Research Center Einstein Professor of Chemistry, City College of New York

1998-2014 Professor of Biophysics and Biochemistry, UT Southwestern Medical Center 1995-1998 Postdoc – Biomolecular NMR methods development, University of Toronto (w/ Dr. Lewis E.

Kay) 1989-1995 Ph.D. – Molecular Biophysics & Biochemistry, Yale University (w/ Dr. Joseph E. Coleman)

Dr. Kevin H. Gardner

Publications Chan, K.L. et al. Characterization of the Zn(II) Binding Properties of the Wilms’ Tumor Suppressor Protein C-Terminal Zinc Finger Peptide”, Inorg. Chem. 2014, 53, 6309-6320. Gibney, B.R. Heme, Encylcopedia of Biophysics, Gordon Roberts, Ed. Springer, 2013. Gibney, B.R. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability in Protein Folding and Metal Ions – Mechanisms, Biology and Disease, Gomes, C and Wittung-Stafshede, P. Eds. 2011, 227-245. Deng, B. et al. Unique Heme Pocket in Human Ncb5or and Structural Basis for Intra-Domain Electron Transfer. J. Biol. Chem. 2010, 285, 30181-30191. Reddy, C.J. . et al. Development and Analysis o a Heme Protein Structure-Electrochemical Function Database Nucleic Acids Reseach 2008, 36, D307-D313. Reddi, A.R. et al. Deducing the Energetic Cost of Protein Folding in Zinc Finger Proteins Using Designed Metallopeptides. J. Am. Chem. Soc. 2007, 129, 12815-12827.

Research Interests Keywords: De novo metalloprotein design, inorganic coordination chemistry, biophysics, bioenergetics, electrochemistry Our research focuses on the role of metal ions in biological systems from both an inorganic coordination chemistry and biophysical perspective. We are currently investigating the role of zinc in controlling gene expressions in human cancer, and the role of heme proteins in cardiovascular disease.

The Gibney Lab uses metalloprotein design to investigate the fundamental engineering of biological systems. These studies provide insight into metal-induced protein folding, heme electrochemistry, and the role of chemically modified hemes in biology.

2018- current Associate Professor Brooklyn College 2005-2008 Associate Professor Columbia University 2000-2005 Assistant Professor Columbia University 1995-2000 NIH Postdoc University of Pennsylvania 1990-1995 PhD University of Michigan 1986-1990 BS (ACS Certified) Florida State University

Dr. Brian R. Gibney

Brian R. Gibney Associate Professor Brooklyn College 2900 Bedford Avenue Brooklyn, NY 11210 bgibney@broklyn.cuny.edu http://www.biochemistry.nyc

Michael E Green Professor City College of New York Dept. of Chemistry 160 Convent Ave New York NY 10031 green@sci.ccny.cuny.edu http://forum.sci.ccny.cuny.edu/people/science-division-directory/b009

Publications A. M. Kariev and M. E. Green, "Caution is required in interpretation of mutations in the voltage sensing domain of voltage gated channels as evidence for gating mechanisms.," Int'l J. Molec. Sci. (2015) 16, 1627-1643. A. M. Kariev and M. E. Green, "Quantum Effects in a Simple Ring with Hydrogen Bonds " J. Phys. Chem. B (2015)119,5962-5969 A. M. Kariev, P. Njau, and M. E. Green, "The Open Gate of the Kv1.2 Channel: Quantum Calculations Show The Key Role Of Hydration," Biophys J. (2014). 106, 548-555 A. M. Kariev and M. E. Green, "Voltage Gated Ion Channel Function: Gating, Conduction, and the Role of Water and Protons," Int'l J. Molec. Sci. (2012) 13, 1680-1709

S. Liao and M. E. Green, "Quantum calculations on salt bridges with water: Potentials, structure, and properties," Comput. Theo. Chem. (2011) 963, 207-214.

Research Interests Keywords: Description of research activities and strategy.

Dr. Green is a computational chemist, with a principal in terest in b iophysical problems, especially related to a class of proteins, ion channels, responsible for the nerve impulse, among other things.

Dr. Green has been a faculty member in Chemistry at CCNY since Sept 1966.

Research Interests    Keywords: Quantum calculations, proteins, water structure, hydrogen bonds, salt bridges, membranes, water transport through membranes Research Strategy: Primarily we carry out quantum calculations on overlapping sections of proteins, such as voltage sensing domains of ion channels, to determine structure, bonding, energetics, and transitions of protein, water, hydrogen bonds, and salt bridges, leading to mechanisms, for example, of sensing voltage.

Dr. Michael Green

Name Steve Greenbaum Position Professor of Physics Affiliation Hunter College Address 695 Park Avenue Address 1220N New York NY 10065 Email.steve.greenbaum@hunter.cuny.edu www.hunter.cuny.edu/physics/faculty/greenbaum

Publications  “An  Iodide  Based  Li7P2S8I  Superionic  Conductor”,  with  Ezhiylmurugan  Rangasamy,  Zengcai  Liu,  Mallory  Gobet,  KarLk  Pilar,  Gayatri  Sahu,  Wei  Zhou,  Hui  Wu,  and  Chengdu  Liang,  Journal  of  the  American  Chemical  Society,  137(4):1384-­‐7  (2015):      “ComparaLve  Study  of  Ether-­‐Based  Electrolytes  for  ApplicaLon  in  Lithium−Sulfur  BaTery”,  with  Lorenzo  Carbone,  Mallory  Gobet,  Jing  Peng,  MaThew  Devany,    Bruno  ScrosaL,  and  Jusef  Hassoun,  Applied  Materials  &  Interfaces  (ACS),    (2015),    7,  13859−13865:    “InteracLons  between  water  and  1-­‐butyl-­‐1-­‐methylpyrrolidinium  ionic  liquids”,  with  TaLana  A.  Fadeeva  ,    Pascale  Husson,  Jessalyn  A.  DeVine,    Margarida  F.  Costa  Gomes,  and  Edward  W.  Castner,  Jr.,  Journal  of  Chemical  Physics,  143,  064503  (2015);      “Novel  Solid  Polymer-­‐in-­‐Ceramic  Electrolyte  Formed  by  ElectrophoreLc  DeposiLon”,  with  R.  Blanga,  L.  Burstein,  M.  Berman,  and  D.  Golodnitsky.  Journal  of  the  Electrochemical  Society,  162(11)  D3084-­‐D3089  (2015);    “On  order  and  disorder  in  polymer  electrolytes”  with  D.  Golodnitsky,  E.  Strauss,  E.  Peled,  Journal  of  the  Electrochemical  Society,  162  (14)  A2551-­‐A2566  (2015).    “Electrolytes  for  Secondary  Magnesium  BaTeries  Based  on  Chloroaluminate  Ionic  Liquids”,  with  Federico  Bertasi,  Chaminda  Heyge,  Fatemeh  Sepehr,  Xavier  Bogle,  Gioele  Pagot,  KeL  Vezzù6,  Enrico  Negro,  Stephen  J.  Paddison,  Michele  ViTadello,  and  Vito  Di  Noto,  ChemSusChem,  8,  3069-­‐3076  (2015).      “Polyethylene  glycol  dimethyl  ether  (PEGDME)-­‐based  electrolyte  for  lithium  metal  baTery”,  with  Lorenzo  Carbone,    Mallory  Gobet,    Jing  Peng,    MaThew  Devany,    Bruno  ScrosaL,  and  Jusef  Hassoun,  Journal  of  Power  Sources,  299,  460-­‐464  (2015).  

Research Interests Keywords: Nuclear magnetic resonance, electron paramagnetic reson- ance, structure of disordered solids battery and fuel cell Materials characterization

We  invesLgate  the  structure  and  funcLon  of  solid  materials  at  the  atomic  and  molecular  level  by  solid  state  NMR.  Most  of  these  materials  have  applicaLon  in  renewable  energy  technologies.  I  value  diversity  in  the  scienLfic  workforce  as  reflected  by  my  lab  group  members.  

1983- current Current position 1981-83 Postdoc, Naval Research Lab 1976-81 PhD, Brown University

Dr Steve Greenbaum

Professor Hunter College of CUNY Dept. of Chemistry & Biochemistry 695 Park Avenue New York NY 10065 ngreenba.hunter@cuny.edu www.cuny.edu/chemistry/faculty/nancy/greenbaum

Publications Zhao,   C,   Devany,   M,   Greenbaum,   NL   (2014)  Measurement  of  Chemical  Exchange  between  RNA   Conformers   by   19F   NMR.     Biochem.  Biophys.  Res.  Comm.  453,692-­‐695.     Popović,   M,   Greenbaum,   NL   (2014)   Role   of  helical  constraints  of  the  EBS1-­‐IBS1  duplex  of  a   group   II   intron   on   demarcaLon   of   the   5ʹ′  splice  site.    RNA  20,  24-­‐35.     Zhao,  C*,  Bachu,  R*,  Popović,  M,  Devany,  M,  Brenowitz,  M,  SchlaTerer,  JC,  Greenbaum,  NL  (2013)   ConformaLonal   heterogeneity   of   the  protein-­‐free   human   spliceosomal   U2-­‐U6  snRNA   complex.   RNA   19,   561-­‐573.     *these  authors  contributed  equally  to  the  work.     Popović,   M,   Nelson,   JD,   Schroeder,   KT,  Greenbaum,   NL   (2012)   Impact   of   base   pair  idenLty   5ʹ′   to   the   spliceosomal   branch   site  adenosine  on  branch  site  conformaLon.    RNA  18,  2093-­‐2103.     Yuan,   F,   Griffin,   L,   Phelps,   L,   Buschmann,   V,  Weston,   K,   Greenbaum,   NL   (2007)   Use   of   a  novel   Förster   resonance   energy   transfer  method   to   idenLfy   locaLons   of   site-­‐bound  metal   ions   in   the   U2-­‐U6   snRNA   complex.    Nucleic  Acids  Res.  35,  2833-­‐2845.  

Research Interests Keywords: RNA, spliceosome, NMR We  aTempt  to  answer  quesLons  about  how  RNA  molecules  fold  and  interact  with  other  RNA,  metal  ions,  and  proteins  in  order  to  carry  out  the  complex  acLvity  of  precursor  messenger  (pre-­‐m)RNA  splicing.  This  process,  by  which  noncoding  intron  sequences  of  pre-­‐mRNA  molecules  are  excised  and  flanking  coding  exons  are  ligated  together,  is  an  essenLal  step  in  preparaLon  of  mRNA  transcripts  prior  to  translaLon  of  their  message  into  protein  sequences.    Pre-­‐mRNA  splicing  in  eukaryoLc  cells  is  performed  by  the  spliceosome,  a  dynamic  nuclear  supramolecular  assembly  that  comprises  five  recyclable  small  nuclear  (sn)RNA  molecules  and  many  proteins.  SimilariLes  between  spliceosomal  snRNAs  of  and  funcLonally  analogous  regions  of  Group  II  introns,  which  excise  themselves  even  in  the  absence  of  proteins,  suggests  shared  evoluLonary  ancestry  and  the  likelihood  that  the  spliceosomal  reacLon  is  also  catalyzed  by  its  RNA  components.  Using  a  combinaLon  of  biochemistry,  biophysical,  and  spectroscopy  techniques,  we  characterize  the  molecular  basis  of  recogniLon  and  conformaLonal  dynamic  leading  RNA  splicing  in  the  two  systems.

Prof. Greenbaum is a structural biologist whose research addresses the role of biomolecular structure and funct ion in biochemical activity of noncoding RNA molecules. We incorporate solution NMR, fluorescence techniques, and biochemical approaches in our studies.

2007- current Professor, Hunter College 2004-2007 Associate Professor, Florida State Univ. 1997-2004 Assistant Professor, Florida State Univ. 1992-1996 Postdoc, Columbia University 1985-1989 Postdoc, Rockefeller University 1981-1984 PhD, University of Pennsylvania

Dr. Nancy Greenbaum

Name: Alexander Greer Position: Professor Affiliation: CUNY Brooklyn College, Dept. Chemistry Brooklyn, NY 11210 718-951-5000 ext 2830 agreer@brooklyn.cuny.edu http://academic.brooklyn.cuny.edu/chem/agreer/FirstPage.html 1999-current Professor 1997-1999 Postdoc, UCLA 1994-1996 PhD, University of Wyoming

Dr. Alexander Greer Publications M.   S.   Oliveira,   M.   S.;   Ghogare,   A.   A.;  Abramova,  I.  ;  Greer,  E.  M.;  Prado,  F.  M.  ;  Di  Mascio,   P.;     Greer,   A.   Mechanism   of  Photochemical   O-­‐Atom   Exchange   in  Nitrosamines   with   Molecular   Oxygen.   J.  Org.  Chem.  2015,  80,  6119-­‐6127.    Ghogare,  A.  A.;  Rizvi,  I.;  Hasan,  T.;  Greer,  A.  Pointsource   Delivery   of   a   PhotosensiLzer  Drug   and   Singlet   Oxygen:   EradicaLon   of  Glioma   Cells   in   Vitro.   Photochem.  Photobiol.  2014,  90,  1119-­‐1125.    Aebisher,  D.;   Bartusik,  D.;   Liu,   Y.;   Zhao,   Y.;  Barahman,  M.;  Xu,  Q.;  Lyons,  A.  M.;  Greer,  A.   Superhydrophobic   PhotosensiLzers.  MechanisLc   Studies   of   1O2   GeneraLon   in  the   Plastron   and   Solid/Liquid   Droplet  Interface.   J.   Am.   Chem.   Soc.   2013,   135,  18990-­‐18998.    Bartusik,   D.;   Aebisher,   D.;   Ghosh,   G.;  Minnis,  M.;  Greer,   A.   Fluorine   End-­‐Capped  OpLcal   Fibers   for   PhotosensiLzer   Release  and   Singlet   Oxygen   ProducLon.   J.   Org.  Chem.  2012,  77,  4557-­‐4565.    Zamadar,   M.;   Ghosh,   G.;   Mahendran,   A.;  Minnis,   M.;   Kru�,   B.   I.;   Ghogare,   A.   A.;  Aebisher,  D.;  Greer,  A.  PhotosensiLzer  Drug  Delivery   via   an  OpLcal   Fiber.   J.  Am.  Chem.  Soc.  2011,  133,  7882-­‐7891.    Greer,   A.   Organic   Chemistry:     Molecular  Crosstalk.  Nature  2007,  447,  273-­‐274  .

Our key research areas are organic chemistry, synthesis, photochemistry, medical devices, drug design, lasers, green chemistry, nanotechnology

Research Interests Our work has focused on photosensitized oxidation reactions that are toxic to organisms and damaging to materials, and can be harnessed for applications such as the disinfection of water supplies. Because a critical need for mechanistic strategies that can generate photosensitized intermediates in a clean and pure fashion, our published results focus on the physical isolation of sensitizer and molecules at surfaces to “separate” singlet oxygen from other reactive oxygen species (ROS). We have a longstanding interest in photooxygen atom transfer processes related to thiophene sulfoxides and nitrosamines. Our work is also involved the synthesis and mechanistic studies of organic sulfanes related to natural product thianthrene, tetrathiocin, trithiole, and pentathiepin anticancer agents.

Dr. Dixie Goss Hunter College Chemistry Dept. 695 Park Ave New York, NY 10065 dgoss@hunter.cuny.edu http://www.hunter.cuny.edu/chemistry/faculty/Dixie/goss-group-1/resume

Publications  Recruitment of 40S Ribosome to the 3' Untranslated Region (UTR) of a Viral mRNA, via the eIF4F Complex, Facilitates Cap-independent Translation. Das Sharma S, Kraft JJ, Miller WA, Goss DJ. J Biol Chem. 2015 Mar 19. Pokeweed antiviral protein, a ribosome inactivating protein: activity, inhibition and prospects. Domashevskiy AV, Goss DJ. Toxins (Basel). 2015 Jan 28;7(2):274-98. Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions. Khan MA, Ma J, Walden WE, Merrick WC, Theil EC, Goss DJ. Nucleic Acids Res. 2014 Jun;42(10):6567-77. Eukaryotic initiation factor (eIF) 4F binding to barley yellow dwarf virus (BYDV) 3'-untranslated region correlates with translation efficiency. Banerjee B, Goss DJ. J Biol Chem. 2014 Feb 14;289(7):4286-94. Poly(A) binding proteins: are they all created equal? Goss DJ, Kleiman FE. Wiley Interdiscip Rev RNA. 2013 Mar-Apr;4(2):167-79.

Research Interests Keywords: protein synthesis, virus, protein-nucleic acid interactions We use biophysical approaches to understand how non-coding regions of mRNA regulate function. Miss regulation of protein synthesis in responsible for many diseases including cancer. We are interested in how unique structures in viral RNA allow viruses to take over host cell protein synthesis.

Prof. Goss is a professor of Chemistry and Biochemistry and Elion Endowed Scholar

1990- current Professor of Chemistry 1989-1990 Associate Professor of Chemistry 1984-1989 Assistant Professor

Post-Doc. U. of Nebraska and U. of Georgia

1975 Ph.D U. of Nebraska

Dr. Dixie J. Goss

Wayne W. Harding, PhD Associate Professor Hunter College Chemistry Dept. 695 Park Avenue New York NY 10065 whardi@hunter.cuny.edu http://www.hunter.cuny.edu/chemistry/faculty/Harding/Wayne

Publications

Research Interests Keywords: Medicinal chemistry, drug design, organic synthesis, central nervous system, CNS, receptor, serotonin, dopamine

D r. H a r d i n g i s a o r g a n i c / m e d i c i n a l chemist with interests in the design, synthesis a n d e v a l u a t i o n o f l igands for centra l n e r v o u s s y s t e m receptors.

2013- current Associate Professor, Hunter College 2006-2013 Assistant Professor, Hunter College 2004-2006 Postdoctoral Fellow, University of Iowa 1994-1999 Ph.D.

Dr. Wayne Harding Aporphinoid antagonists of 5-HT2A receptors: further evaluation of ring A substituents and the size of ring C. S. Ponnala, N. Kapadia, H. A. Navarro, W. W. Harding, Chem. Biol. Drug Des. 2014, 84, 558 - 566. Evaluation of structural effects on 5-HT2A receptor antagonism by aporphines: identification of a new aprophine with 5-HT2A antagonist activity. S. Ponnala, J. Gonzales, N. Kapadia, H. A. Navarro, W. W. Harding, Bioorg. Med. Chem. Lett. 2014, 24, 1664 - 1667. New Aporphinoid 5-HT2A and α1Α antagonists via structural manipulations of nantenine. S. Chaudhary, S. Ponnala, O. LeGendre, J. Gonzales, H. A. Navarro, W. W. Harding, Bioorg. Med. Chem. 2011, 19, 5861-5868. Affinity of aporphines for the human 5-HT2A receptor: insights from homology modeling and molecular docking studies. S. Pecic, S. Chaudhary, P. Makkar, B. J. Reddy, H. A. Navarro, W. W. Harding, Biorg. Med. Chem. 2010, 18, 5562 - 5575. (±)-Nantenine analogs as antagonists at human 5-HT2A receptors: C1 and flexible congeners, S. Chaudhary, O. LeGendre, S. Pecic, H. A. Navarro, W. W. Harding Biorg. Med. Chem. Lett. 2009, 19, 2530 -2532.

William H. Hersh Professor Department of Chemistry and Biochemistry Queens College 65-30 Kissena Blvd. Queens, NY 11367-1597 william.hersh@qc.cuny.edu http://chem.qc.cuny.edu/~whersh

Publications S. Malik, A. Tarpanova, D. Lichtman, Y. Wallach, J. A. Mukhlall, W. H. Hersh, “Synthesis of Dixanthates and Dithiocarbonyl Disulfides as Models for Poly(disulfide)s, in preparation, 2015. W. H. Hersh, “Synthesis of dinucleoside acylphosphonites by phosphonodiamidite chemistry and investigation of phosphorus epimerization,” Beilstein J. Org. Chem. 2015, 11, 184-191. W. H. Hersh, S. T. Lam, D. J. Moskovic, A. J. Panagiotakis, “A Non-Karplus Effect: Evidence from Phosphorus Heterocycles and DFT Calculations of the Dependence of Vicinal Phosphorus-Hydrogen NMR Coupling Constants on Lone-Pair Conformation,” J. Org. Chem. 2012, 77, 4968-4979. J.  A.  Mukhlall,  W.  H.  Hersh,     “SulfurizaLon  of   Dinucleoside   Phosphite   Triesters   with  Chiral   Disulfides,”  Nucleosides,   Nucleo:des  &  Nucleic  Acids  2011,  30,  706-­‐725.  

Dr. Hersh is an organic chemist with current research projects on synthesis of chiral oligonucleotide phosphorothioates and helical disulfide polymers. Specialties include NMR, X-ray crystallography, and DFT calculations.

1989 - current Queens College 1982 - 1989 UCLA 1980 – 1982 Postdoc, UC Berkeley 1980 PhD, Columbia University

Dr. William Hersh

Edward G. Hohenstein Assistant Professor City College of New York Marshak Science Building, Rm. 1032 160 Convent Avenue New York, NY 10031 ehohenstein@ccny.cuny.edu http://www.hohenstein-chem.com

Publications E.G. Hohenstein, Mechanism for the Enhanced Excited-State Lewis Acidity of Methyl Viologen, J. Am. Chem. Soc., 2016, 10.1021/jacs.5b08177 E.G. Hohenstein, M.E.F. Bouduban, C. Song, N. Luehr, I.S. Ufimtsev, and T.J. Martínez, Analytic First Derivatives of Floating Occupation Molecular Orbital-Complete Active Space Configuration Interaction on Graphical Processing Units, J. Chem. Phys., 2015, 143, 014111 E.G. Hohenstein, N. Luehr, I.S. Ufimtsev, and T.J. Martínez, An Atomic Orbital-Based Formulation of the Complete Active Space Self-Consistent Field Method on Graphical Processing Units, J. Chem. Phys., 2015, 142, 224103 E.G. Hohenstein, R.M. Parrish, C.D. Sherrill, and T.J. Martínez, Tensor Hypercontraction. III. Least-Squares Tensor Hypercontraction for the Determination of Correlated Wavefunctions, J. Chem. Phys., 2012, 137, 221101

Research Interests Keywords: Theoretical, Computational, Photochemistry The accurate treatment of excited electronic states is a uniquely challenging and important problem in electronic structure theory. We are actively developing new methods for treating excited states as well as highly efficient and scalable implementations of these methods that exploit modern advances in computer hardware. We apply these methods to problems in photochemistry. Processes occurring in the condensed phase, such as excited-state proton transfer, are of particular interest. We are also working to apply similar methodology to design light harvesting complexes.

Prof. Hohenstein is a t h e o r e t i c a l c h e m i s t s p e c i a l i z i n g i n t h e d e v e l o p m e n t a n d implementation of new e l e c t r o n i c s t r u c t u r e methodology and the appl icat ion of these methods to problems in excited-state chemistry.

2014- current Assistant Professor, CCNY 2011-2014 Postdoc, Stanford University 2007-2011 PhD, Georgia Institute of Technology

Dr. Edward G. Hohenstein

Qiao-Sheng Hu Professor and Chair Department of Chemistry College of Staten Island 2800 Victory Blvd. Staten Island, NY 10314 qiaosheng.hu@csi.cuny.edu http://www.csi.cuny.edu/departments/chemistry

Publications H.-H. Zhang, C.-H. Xing, G. B.Tsemo, Q.-S.Hu, t-Bu3P-Coordinated 2-Phenylaniline-Based Palladacycle Complex as a Precatalyst for the Suzuki Cross-Coupling Polymerization of Aryl Dibromides with Aryldiboronic Acids, ACS MacroLett. 2013, 2, 10-13. H.-H. Zhang, C.-H. Xing, Hu, Q.-S., Controlled Pd(0)/t-Bu3P-Catalyzed Suzuki Cross-Coupling Polymerization of AB-Type Monomers with PhPd(t-Bu3P)I or Pd2(dba)3/t-Bu3P/ArI as the Initiator, J. Am. Chem. Soc. 2012, 134, 13156-13159. T.-P. Liu, Y.-X. Liao, C.-H. Xing, Q.-S. Hu, Fluorenone Synthesis by Palladacycle-Catalyzed Sequential Reactions of 2-Bromobenzaldehydes with Arylboronic Acids, Org. Lett. 2011, 13, 2452-2455. T.-P. Liu, C.-H. Xing, Q.-S. Hu, Tandem Reaction Synthesis of Fluorenes/ Indenofluorenes Based on Pd(OAc)2/PCy3-Catalyzed Suzuki Cross-Coupling and C-H Bond Activation Strategy, Angew. Chem. Int. Ed. 2010, 49, 2971-2974. C.-G. Dong, Q.-S. Hu, Preferential Oxidative Addition in Palladium(0)-Catalyzed Suzuki Cross-Coupling Reactions of Dihaloarenes with Arylboronic Acids, J. Am. Chem. Soc. 2005, 127, 10006-10007.

Research Interests Keywords: catalysis, palladium, cross-coupling reaction, polymerization, conjugated polymers The Hu group are interested in the development of new catalysts including transition metal and organic catalysts for cross-coupling reactions and addition reactions, and novel reactions/processes from readily available and cost-effective small organic molecules. These new reactions/processes and catalysts have potential applications in chemical synthesis and polymer/materials synthesis. The approach is interdisciplinary, ranging from fundamental understanding of reaction mechanisms, reaction methodology development to polymer/materials synthesis.

Q i a o - S h e n g H u i s Professor and Chair of Chemistry Department at the College of Staten Island. His research is focused on the development of new reactions/processes and catalysts for chemical synthesis including polymer/ materials synthesis.

2008- current Professor, CSI-CUNY 2005-2007 Associate Professor, CSI 2000-2005 Assistant Professor, CSI 1997-2000 Postdoc, University of Virginia 1995-1997 Postdoc, North Dakota state Univ. 1991-1994 PhD, Shanghai Institute of Organic Chemistry,

Chinese Academy of Sciences

Dr. Qiao-Sheng Hu

Urs Jans Associate Professor Department of Chemistry and Biochemistry City College of New York 160 Convent Avenue New York NY, 10031 ujans@ccny.cuny.edu www.ccny.cuny.edu/profiles/urs-jans

Publications D. Saint-Hilaire, U. Jans, Reactions of three halogenated organophosphorus flame retardants with reduced sulfur species. Chemosphere, 2013, 93, 2033-2039. L. Yang, X. Li, P. Zhang, M. Melcer, Y. Wu, U. Jans. Concentrations of DDTs and dieldrin in Long Island Sound sediment, Journal of Environmental Monitoring, 2012, 14, 878-885. K.W. Lo, S.C. Saha-Roy, U. Jans. Investigation of the reaction of hexabromocyclododecane with polysulfide in methanol/water solutions, Chemosphere, , 2012, 87, 158-162. D. Saint-Hilaire, K.Z. Ismail, U. Jans. Reactions of tris(2-chloroethyl)phosphate with reduced sulfur species, Chemosphere, 2011, 83, 941-947. L. Yang, X. Li, J. Crusius, U. Jans, M. E. Melcer, P. Zhang. Persistent chlordane concentrations in Long Island Sound sediment: Implications for chlordane, 210Pb, and 137Cs depth profiles. Environ. Sci. Technol., 2007, 41, 7723-7729.

Research Interests Keywords: Environment, emerging contaminants, abiotic transformation, analytical chemistry My research program at CCNY is addressing questions concerning environmental organic chemistry, with a focus on the mechanisms through which organic contaminants undergo abiotic transformations in natural aquatic environment (freshwater, seawater). We also determine the concentration of organic contaminants in sediments and soils as a tool to understand their accumulation in the environment.

Dr. Jans is interested in the fate of organic conta-minants (e.g., pesticides, flameretardants) in the environment.

1999- current City College of New York 1996-1998 Postdoc, Johns Hopkins University 1992-1996 PhD, ETH Zürich, Switzerland

Dr. Urs Jans

David Jeruzalmi Professor of Chemistry Marshak 1219 • City College of New York • Graduate Center of the City University of New York 160 Convent Avenue New York, NY 10031 dj@ccny.cuny.edu

Publications Lu, M., Yang, J., Ren, Z., Sabui, S., Espejo, A., Bedford, M. T., et al. (2009). Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150. Journal of Molecular Biology, 393(2), 397–408. Pakotiprapha, D., & Jeruzalmi, D. (2013). Smal l -angle X-ray scat ter ing reveals architecture and A(2) B(2) stoichiometry of the UvrA-UvrB DNA damage sensor. Proteins: Structure, Function, and Bioinformatics, 81(1), 132–139. Pakotiprapha, D., Liu, Y., Verdine, G. L., & Jeruzalmi, D. (2009). A structural model for the damage-sensing complex in bacter ial nucleotide excision repair. The Journal of Biological Chemistry, 284(19), 12837–12844. Pakotiprapha, D., Samuels, M., Shen, K., Hu, J. H., & Jeruzalmi, D. (2012). Structure and mechanism of the UvrA–UvrB DNA damage sensor. Nature Structural & Molecular Biology, 1–9. Samuels, M., Gulati, G., Shin, J.-H., Opara, R., McSweeney, E., Sekedat, M., et al. (2009). A biochemically active MCM-like helicase in Bacillus cereus. Nucleic Acids Research, 37(13), 4441–4452. Research Interests

The faithful transmission of gene1c information is an important biological imperative. To carry out this function, organisms have evolved processes to replicate their genomes and defend them from attack. We study important mechanisms associated with the processes of DNA replica1on and repair. The central challenge in understanding these processes stems from the large size of the involved multi-protein DNA complexes; these entities also populate many conformational states. Together, these complications place limits on insights that can be revealed by static crystallographic structures or solution methods alone; both sources of information are essential for defining underlying mechanisms. To this end, my group applies X-ray crystallography, supplemented with electron microscopy, to understand these long-standing problems in DNA biology. We also use biochemical studies to inform these approaches and follow up on the resulting insights.

2012- current Professor of Chemistry, CCNY 2002-2012 Molecular and Cellular Biology, Harvard 1996-2002 The Rockefeller University 1994 Ph.D., Yale University

Dr. David Jeruzalmi Jeruzalmi’s group applies X - r a y c r y s t a l l o g r a p h y, supplemented with electron microscopy, to understand these long-standing problems in DNA biology. We also use biochemical studies to inform these approaches and follow up on the resulting insights.

Shi Jin Associate Professor College of Staten Island 2800 Victory Blvd Staten Island, NY 10314 shi.jin@csi.cuny.edu http://www.csi.cuny.edu/faculty/JIN_SHI.html

Publications D. D. Gunbas, C. Xue, S. Patwardhan, M. C. Fravventura, H. Zhang, W. F. Jager, E. J. R. Sudholter, L. D. A. Siebbeles, T. J. Savenije, S. Jin, F. C. Grozema, High charge carrier mobility and efficient charge separation in highly soluble perylenetetracarboxyl-di imides Chemical Communications 2014, 50, 4955. N. Jin, H. Zhang, S. Jin, M. D. Dadmun, B. Zhao, Shifting Sol-Gel Phase Diagram of a Doubly Thermosensitive Hydrophilic Diblock Copolymer Poly(methoxytri(ethylene glycol) acrylate-co-acrylic acid)-b-poly(ethoxydi(ethylene glycol) acrylate-co-acrylic acid) in Aqueous Solution Macromolecules 2012, 45, 4790. C. Xue, S. Jin, Exceptionally Strong Electronic Coupling in Crystalline Perylene Diimides via Tuning Chemistry of Materials 2011, 23, 2689. Y. J. Xu, S. W. Leng, C. M. Xue, R. K. Sun, J. Pan, J. Ford, S. Jin, A room-temperature liquid-crystalline phase with crystalline π stacks Angewandte Chemie-International Edition 2007, 46, 3896.      

Research Interests Keywords: Soft Matter, organic optoelectronic materials

Dr. Jin is a physical/materials chemist who is working on structure design, synthesis, characterization and optimization of organic optoelectronic materials for improved performance in devices such organic solar cells, light emitting diodes and field effect transistors,.

2004- 2011 Assistant Prof. of Chemistry, CUNY 2012-current Associate Prof. of Chemistry, CUNY

Dr. Shi Jin

Andrei Jitianu Associate Professor Lehman College 250 Bedford Park Boulevard West Bronx,10468 NY andrei.jitianu@lehman.cuny.edu http://www.lehman.edu/academics/chemistry/prof-jitianu.php

Publications L. Predoana, A Jitianu, S. Preda, B. Malic, M. Zaharescu, Thermal behavior of Li-Co-citric acid water based gels as precursors for LiCoO2 powders, Journal of Thermal Analysis and Calorimetry, 2015, 119, 145-153. L. C. Klein , B. McClarren, and A. Jitianu, Silica-Containing Hybrid Nanocomposite “Melting Gels”, Materials Science Forum, 2014, 783-786, 1432-1437. M. Jitianu, DC. Gunness, DE. Aboagye, M. Zaharescu, A. Jitianu, Nanosized Ni-Al layered double hydroxides - Structural characterization, Materials Research Bulletin, 2013, 48, 1864-1873. L. Gambino, A. Jitianu, L.C. Klein, Dielectric behavior of organically modified siloxane melting gels, Journal Of Non-Crystaline Solids 2012, 24, 3501-3504. A. Jitianu, K. Lammers, G.A. Arbuckle-Kiel, L.C. Klein, Thermal analysis of organically modified siloxane melting gels, Journal of Thermal Analysis and Calorimetry, 2012, 107, 2039-2045.

Research Interests Keywords: Sol-gel, Nanocomposites, Hybrids Organic- Inorganic, Coatings, My studies range from the elucidation of early stages of formation of the hybrid materials by sol-gel process to the design of hybrid nanocomposite materials with magnetic, gas-sensing, electric and optical properties. At Lehman my research was mainly focused to developing a new class of materials called Hybrid Melting Gels for hermetic applications in the microelectronics industry and for optical applications. Beside this, studies of nanoparticles or nanocomposites in different systems have been carried out.

J i t ianu ’s r esea rch i s f ocused on ma te r i a l s chemistry, specifically on sol-gel chemistry with directt applications in anticorrosive, hermetic coat ings and nanomaterals for electronic industry.

2013- current Associate Professor, Lehman College-CUNY 2008-2013 Assistant Professor, Lehman College-CUNY 2005-2008 Research Associate, Rutgers University 2002-2003 “Marie Curie” Postdoctoral fellow, University

of Orleans, France 1996-2001 PhD student University of Bucharest, Romania

Dr. Andrei Jitianu

George John Professor of Chemistry The City College of New York Center for Discovery and Innovation (CDI) -14302 85 St. Nicholas Terrace, New York, NY 10031 john@sci.ccny.cuny.edu www.sci.ccny.cuny.edu/~john/

Publications Faure, L.; Nagarajan, S.; Hwang, H.; Montgomery, C. L.; Khan, B. R.; John, G.; Koulen, P.; Blancaflor, E. B.; Chapman, K. D. Synthesis of Phenoxyacyl-Ethanolamides and Their Effects on Fatty Acid Amide Hydrolase Activity, J. Biol. Chem, 2014, 289, (13): 9340-51.   Vijai Shankar, B.; Jadhav. S. R.; Vemula, P. K; John. G. Recent Advances in Cardanol Chemistry in a Nutshell: From a Nut to Nanomaterials, Chem. Soc. Rev., 2013, 42, 427-438, Cover Page feature. Reddy, A. L.M.; Nagarajan, S.; Chumyim, P.; Gowda, S. R.; Dubey, M.; Jadhav, S. R.; John, G.; Ajayan, P. M. Lithium storage mechanisms in purpurin based organic lithium ion battery electrodes, Scientific Reports (Nature) 2012, 2, 960-964. Shankar, B. V.; Jadhav, S. R.; Pradhan, P.; De Carlo, S.; John, G. Adhesive vesicles through adaptive response of a biobased surfactant, Angew. Chem. Int. Ed., 2010, 49, 9509 –9512. Cover Page feature. Jadhav, S. R.; Vemula, P. K.; Kumar, R.; Raghavan, S.; John, G. Sugar-derived phase-selective molecular gelators as model solidifiers for oil spills, Angew. Chem. Int. Ed., 2010, 49, 7695-7698, Cover Page.

Research Interests Keywords: biobased materials, green chemistry, soft materials, biorefinery, biomimetics, phase selective gels, oil structuring agents (food/cosmetics), antibacterial coatings, battery components/energy storage, green surfactants John’s research is rooted in the idea that innovation can be inspired by nature to develop economical and sustainable technologies for a greener future. The group has harnessed crop-based precursors such as sugars, fatty acids and plant lipids to design a unique set of multifunctional soft-materials including polymers, gels and green surfactants. His group has successfully developed environmentally benign antibacterial paints, polymer-coatings, molecular gel technologies, oil spill recovery materials, battery components and oil thickening agents. As soft materials research is highly interdisciplinary and collaborative, John’s lab encourages the blending of such diverse elements including organic synthesis, green chemistry, material chemistry, interfacial phenomena, colloid science and biomimetics.

George John is a Professor of Chemistry/the Center for Discovery and Innovation, the City College of New York -CUNY. His research is focused on molecular design of synthetic lipids, membrane mimics, soft nanomaterials, green energy technologies and organic materials chemistry.

Dr. George John

2012- current Professor of Chemistry, CCNY 2004-2012 Associate Prof. of Chemistry, CCNY 2002-2004 Research Faculty, RPI, NY 1996-2002 JSPS Fellow/Scientist, Japan 1994-1995 Postdoc, University of Twente, NL 1993 PhD Kerala University, India

Laura Juszczak Associate Professor Brooklyn College 3119 Ingersoll Hall 2900 Bedford Ave. New York NY LJUZAK@brooklyn.cuny.edu

Publications S. Eisenberg and L. J. Juszczak “ The Broken Ring: Reduced Aromaticity in Lys-Trp Cations and High pH Tautomer Correlates with Lower Quantum Yield and Shorter Lifetimes.” J Phys Chem B (2014) 7059-69. A. S. Eisenberg and L. J. Juszczak “Relating TrpGlu Dipeptide Fluorescence to Molecular Conformation: The Role of the Discrete Chi 1 and Chi 2 Angles.” J Comp Chem (2013) 34 1549-60. X. Meng, T. Harricharan, L.J. Juszczak “Substituted indoles lift 1La –1Lb transition degeneracy - a spectroscopic study.” Photochem Photobiol (2013) 89, 40-50. . L.J. Juszczak, R.Z.B. Desamero. "Extension of the Tryptophan Dihedral Angle - W3 Band Frequency Relationship to a Full Rotation: Correlations and Caveats." Biochemistry 48 (2009) 2777-2787.

Research Interests Keywords: Tryptophan photophysics, fluorescent probe synthesis, fluorescence and UV resonance Raman spectroscopy, molecular dynamics/quantum mechanics calculations

Laura Juszczak i s a phys ica l chemis t w i th extensive experience in spectroscopic study of tryptophan in proteins. Group expertise allows extension to theoretical study. A new area of interest i s d e v e l o p m e n t o f biologically compatible, Trp-based visible fluorophores (PHOXI).

2006- current assistant/associate professor 1999-2006 research associate, A. Einstein Coll. of Med. 1992-1999 Postdoc, AECOM 1992 PhD, New York University

Dr Laura Juszczak

Akira Kawamura Associate Professor Hunter College 695 Park Avenue New York NY 10065 akawamur@hunter.cuny.edu www.hunter.cuny.edu/chemistry/faculty/Kawamura

Publications Mihai,  D.M.,  Hall,  S.,  Deng,  H.,  Welch,  C.J.,  Kawamura,  A.  Bioorg.  Med.  Chem.  Le^.  2015,  Nov  15;25(22):5349-­‐51.  PMID:  26420066    Li,  X.,  Kawamura,  A.,  Andrews,  C.D.,  Miller,  J.L.,  Wu,  D.,  Tsao,  T.,  Zhang,  M.,  Oren,  D.,  Padte,  N.N.,  Porcelli,  S.A.,  Wong,  C.H.,  Kappe,  S.H.,  Ho,  D.D.,  Tsuji,  M.  J.  Immunol.  2015;195(6):2710-­‐21.  PMID:  26254338      Montenegro,  D.,  Kalpana,  K.,  Chrissian,  C.,  Sharma,  A.,  Takaoka,  A.,  Iacovidou,  M.,  Soll,  C.E.,  Aminova  O.,  Heguy,  A.,  Cohen,  L.,  Shen,  S.,  Kawamura,  A.  Bioorg.  Med.  Chem.  Le^.  2015;25(3):466-­‐9.  PMID:  25547935    Takaoka,  A.,  Iacovidou,  M.,  Hasson,  T.H.,  Montenegro,  D.,  Li,  X.,  Tsuji,  M.,  Kawamura,  A.  Planta  Med.  2014;80(4):283-­‐9.  PMID:  24549928    Hasson,  T.H.,  Takaoka,  A.,  de  la  Rica,  R.,  Matsui,  H.,  Smeureanu,  G.,  Drain,  C.M.  and  Kawamura,  A.  Chem.  Biol.  Drug  Design,  2014;83(4):493-­‐7.  doi:  10.1111/cbdd.12250.  PubMed  PMID:  24495243    

Research Interests Keywords: Natural Products, Phytobacteria, Glycolipids, Immunology We currently focus on immunomodulatory glycolipids of phytobacteria that were detected in several medicinal plants. In addition to medicinal plants, these lipids exist in many other edible plants. At present little is known about their potential health benefits and risks. This is an important problem because human body is continually exposed to various phytobacterial metabolites through consumption of vegetables, fruits, and herbs. To address this problem, we conduct structural and immunological characterization of phytobacterial glycolipids with immunomodulatory activity.

Natural products chemistry focused on phytobacterial metabolites. Chemical messages for microbial interactions.

2008- current Associate Professor, Hunter College 2002-2007 Assistant Professor, Hunter College 1999-2002 Postdoc, Scripps Research Institute 1994-1999 PhD, Columbia University

Dr Akira Kawamura

Reza Khayat Assistant Professor City College of New York Center for Discovery and Innovation 85 Saint Nicholas Terrace; 12316 New York, NY 10031 rkhayat@ccny.cuny.edu www.khayatlab.org

Publications Veesler D, Khayat R, Architecture of a dsDNA viral capsid in complex with its maturation protease. Structure 2014 Feb 4 (22): 1-8 Khayat R, Lee JH, Structural characterization of cleaved, soluble human immunodeficiency virus type-1 envelope glycoprotein trimers. J. Virology, 2013 Sep;87(17):9865-72 Pejchal R, Khayat R, A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield, Science 2011 Nov. 25:334(6059):1097-103 Khayat R, Brunn N, The 2.3-angstrom structure of porcine circovirus 2, 2011 J. Virology Aug; 85(15):7856-62 Khayat R, Lander GC, An automated procedure for detecting protein folds from sub-nanometer resolution electron density, 2010 J. Struct. Bio. Jun; 170(3); 513-21

Research Interests Keywords: cryo-electron microscopy, X-ray crystallography, biophysics, biochemistry, cellular biology We seek to understand the structural and chemical mechanism by which pathogens hijack the cellular machinery of their host for infection and replication. We use a combination of techniques to understand this mechanism at the atomic resolution to relate how chemistry drives biology, and a number of techniques to understand how biology feeds back into chemistry for new pathways to be exploited by the pathogen for infection and replication. We are also interested in developing computational methods to further combine X-ray crystallography with cryo-electron microscopy.

Khayat group studies the structure and function of proteins encoded for and utilized by pathogens to infect and replicate. We use a combination of X-ray c r ys ta l l og raphy, c r yo -e l e c t r o n m i c r o s c o p y, biophysics, biochemistry, and cellular biology to complete these studies.

2012- current Current position 2008-2012 Sr. Research Associate, TSRI 2003-2008 Research Associate, The Scripps

Research Institute 1998-2003 PhD, Columbia University

Dr. Reza Khayat

Mark N. Kobrak Professor Department of Chemistry, Brooklyn College -- CUNY 2900 Bedford Ave. Brooklyn, NY 11210 mkobrak@brooklyn.cuny.edu http://userhome.brooklyn.cuny.edu/mkobrak/

Publications C. H. C. Janssen, A. Sanchez and M. N. Kobrak, Selective Extracction of Metal Ions from Aqueous Phase to Ionic Liquids: A Novel Thermodynamic Approach to Separations, ChemPhysChem, 2014, 15, 3536. C. H. C. Janssen, A. Sanchez, G.-J. Witkamp and M. N. Kobrak, A Novel Mechanism for the Extraction of Metals from Water to Ionic Liquids, ChemPhysChem, 2013, 14, 3806. M. N Kobrak, A Proposed Voltage Dependence of the Ionic Strength of a Confined Electrolyte Based on a Grand Canonical Ensemble Model, J. Phys. Cond. Matt., 2013, 25, 095006. H. Li and M.N. Kobrak, Instantaneous Normal Mode Analysis of a Series of Model Molten Salts, ChemPhysChem, 2012, 13, 1934. M. N. Kobrak and H. Li, Electrostatic Interactions in Ionic Liquids: The Dangers of Dipole and Dielectric Descriptions, Phys. Chem. Chem. Phys., 2010, 12, 1922.

Research Interests Keywords: Ionic Liquids, interfaces, molecular dynamics, thermodynamics The group’s interest in ionic liquids center on using both analytical and simulation techniques to understand this novel class of materials. The group has uncovered structure-property relationships relevant to both viscosity and solvent polarity in ionic liquids, aiding in the development of ionic liquids with optimal properties for applications of interest. Recent projects consider the use of ionic liquids for the extraction of metals from the aqueous phase. Additional interests center on using thermodynamics to understand solid-liquid interfaces. The results demonstrate linkages between macroscopically-observable properties such as surface tension and the microscopic structure of the interface.

M a r k K o b r a k i s a theoretical physical chemist with expertise in classical and quantum dynamics simulations. Current work centers on theoret ical description of ionic liquids, and studies of solid-liquid interfaces.

2013- current Professor, Brooklyn College 2006- 2013 Associate Professor, Brooklyn College 2001- 2006 Assistant Professor, Brooklyn College 2000-2001 Post-doctoral fellow, Notre Dame

University and The Pennsylvania State University

1998-1999 Post-doctoral fellow, University of Houston

1992-1997 PhD, University of Chicago

Dr. Mark N. Kobrak

Sanjai Kumar Associate Professor Queens College, and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York 65-30 Kissena Blvd. Queen, NY 11367 Sanjai.Kumar@qc.cuny.edu http://chem.qc.cuny.edu/~skumar/

Publications Hsin-Pin Ho, et al. “Studies on Quantitative Phosphopeptide Analysis by MALDI Mass Spectrometry Without Label, Chromatography or Calibration Curves” Rapid Communications in Mass Spectrometry 2014, 28(24):2681-9 Dibyendu Dana et al. "Development of a highly potent, selective, and cell-active Inhibitor of cysteine cathepsin L-A hybrid design approach" Chemical Communications (Camb) 2014, 50(74):10875-8 Ivone Gomes et al. "GPR171 is a Hypothalamic G Protein-Coupled Receptor for BigLEN, a Neuropeptide involved in Feeding” Proceedings of the National Academy of Sciences (PNAS) USA, 2013, 110(40), 16211–16216 Tirtha K. Da et al. “Centrosomal Kinase Nek2 Cooperates With Oncogenic Pathways To Promote Metastasis” Oncogenesis, 2013, 2, e69; doi:10.1038/oncsis.2013.34 Dibyendu Dana et al. Development of Cell-Active Non-peptidyl Inhibitors of Cysteine Cathepsins” Bioorganic and Medicinal Chemistry, 2013, 21, 2975-87

Research Interests Keywords: Protein kinases, Nek2 kinase, Cathepsin L, Cathepsin B, PTP1B, Chemical Biology, Small molecule Probes and sensors The research in Kumar’s laboratory spans at the interface of chemistry and biology, and is broadly focused on discovery of unknown enzyme function using chemical biology approaches. The current project includes the development of small molecule probes for protein kinases and protein tyrosine phosphatases, a critically important group of cellular signaling enzymes. The probes are then utilized to understand the enzyme function in both normal physiology and human diseases. Another important area of current interest is to develop appropriate chemical biology tools that can be utilized to probe the function of cysteine cathepsin enzymes in diverse cellular processes. For more information, please visit the website.

Dr. Kumar’s lab studies chemical biology approaches to unders tand enzyme function involved in human diseases. Development of small molecule probes and sensors of protein kinases, p r o t e i n t y r o s i n e phosphatases, and cysteine proteases.

2007- current Associate Prof. of Chemistry, Queens College

2002-2007 PostDoc, Albert Einstein College of Medicine

Dr. Sanjai Kumar

Thomas Kurtzman Assistant Professor Lehman College 250 Bedford Park Boulevard West Bronx,10468 NY http://www.lehman.edu/faculty/tkurtzman/

Publications Wickstrom,  L.  et  al.  ParameterizaLon  of  an  effecLve  potenLal  for  protein-­‐ligand  binding  from  host-­‐guest  affinity  data.  J.  Mol.  Recognit.  (Accepted  Journal  of  Molecular  Recogni:on)  

Nguyen,   C.   N.,   Cruz,   A.,   Gilson,   M.   K.   &  Kurtzman,   T.   Thermodynamics   of   Water   in  an  Enzyme  AcLve  Site:  Grid-­‐Based  HydraLon  Analysis   of   CoagulaLon   Factor   Xa.   J.   Chem.  Theory   Comput.   (2014).   doi:10.1021/ct401110x  

Armaiz-­‐Pena,  G.  N.  et  al.  Src  acLvaLon  by  β-­‐adrenoreceptors  is  a  key  switch  for  tumour  metastasis.  Nat.  Commun.  4,  1403  (2013).  

Nguyen,  C.  N.,  Kurtzman  Young,  T.  &  Gilson,  M.  K.  Grid  inhomogeneous  solvaLon  theory:  HydraLon  structure  and  thermodynamics  of  the  miniature  receptor  cucurbit[7]uril.  J.  Chem.  Phys.  137,  044101–044101–17  (2012)  *Young,  T.,  Abel,  R.,  Kim,  B.,  Berne,  B.  J.  &  Friesner,  R.  A.  MoLfs  for  molecular  recogniLon  exploiLng  hydrophobic  enclosure  in  protein–ligand  binding.  Proc.  Natl.  Acad.  Sci.  104,  808  –813  (2007).    *Formerly  published  as  T.  Young      

Research Interests Keywords: Solvation Thermodynamics, Statistical Mechanics, Computer Aided Drug Design Research  in  the  Kurtzman  lab  focuses  on  the  development  of  computaLonal  tools  that  can  aid  in  the  discovery  and  raLonal  design  of  new  drugs.    His  approach  applies  staLsLcal  mechanical  theory  and  computer  simulaLons  to  beTer  understand  the  physical  principles  that  govern  the  molecular   recogniLon   between   proteins   and   small   molecule   ligands   (drugs).     A   parLcular  emphasis   is   placed   on   the   role   that   water   plays   in   the   molecular   recogniLon   process.     A  principal  goal  of  this  research  is  to  help  design  and  discover  drugs  that  bind  with  high  affinity  and  selecLvity  to  given  protein  targets  

The Kurtzman group focuses on the development of methodologies to characterize the structure and thermodynamics of water on the surface of proteins and the exploitation of solvation properties for the discovery and design of new drugs.

2010- Present Assistant Professor, Lehman College-CUNY 2008-2010 AsssistantProfessor,  San  José  State  Univ.  2007-2008 Visiting Professor, Yeshiva University 2004-2007 Postdoctoral Fellow, Columbia University 2002 Doctorate, Stanford University

Tom Kurtzman

Michal Kruk Professor College of Staten Island and Graduate Center Department of Chemistry, Building 6S-241 2800 Victory Boulevard Staten Island, NY 10314 Michal.Kruk@csi.cuny.edu http://www.csi.cuny.edu/faculty/departments/chemistry/kruk_michal.html

Publications Huang, L.; Kruk, M. “Versatile Surfactant/Swelling-Agent Template for Synthesis of Large-Pore Ordered Mesoporous Silicas and Related Hollow Nanoparticles”, Chem. Mater. 2015, 27, 679. Kruk, M. “Access to Ultra-large-pore Ordered Mesoporous Materials Through Selection of Surfactant/Swelling-Agent Micellar Templates”, Acc. Chem. Res. 2012, 45, 1678. Mandal, M.; Kruk, M. “Family of Single-micelle-templated Organosilica Hollow Nanospheres and Nanotubes Synthesized through Adjustment of Organosilica/Surfactant Ratio”, Chem. Mater. 2012, 24, 123. Cao, L.; Kruk, M. “Grafting of Polymer Brushes from Nanopore Surface via Atom Transfer Radical Polymerization with Activators Regenerated by Electron Transfer”, Polym. Chem. 2010, 1, 97.

Research Interests Keywords: ordered mesoporous materials, hollow nanoparticles, controlled surface-initiated radical polymerization •  Design of ordered nanoporous materials. •  Application of controlled polymerizations in the synthesis of nanostructured materials, including porous

inorganic/polymer nanocomposites. •  Development of methods for accurate characterization of nanoporous materials. •  Synthesis of nanoporous materials with closed pores. •  Synthesis of single-micelle-templated hollow nanoparticles.

Michal Kruk is a professor in chemistry. His research interest is in design of well-defined nanoporous and nanostructured materials using surfactant micelle templating, nanocasting and controlled surface-initiated polymerization.

2013- current Professor 2011-2013 Associate Professor 2005-2010 Assistant Professor 2003-2005 Visiting Assistant Professor 1998-2003 Postdoctoral fellow 1994-1998 PhD Student in Chemistry

Dr. Michal Kruk

Mahesh Lakshman Professor The City College of New York Department of Chemistry 160 Convent Avenue New York NY mlakshman@ccny.cuny.edu www.sci.ccny.cuny.edu/~mkl

Publications §  M. Singh, M. K. Lakshman, Diarylmethanes via an unprecedented Pd-catalyzed C–C cross coupling of 1-(aryl)methoxy-1H-benzotriazoles with arylboronic acids, ChemCatChem. 2015, 7, accepted for publication. §  P. F. Thomson, D. Parrish, P. Pradhan, M. K. Lakshman, Modular, metal-catalyzed, cyclo-isomerization approach to angularly-fused polycyclic aromatic hydrocarbons and their derivatives, J. Org. Chem. 2015, 80, 7435–7446. §  R. R. Chamala, D. Parrish, P. Pradhan, M. K. Lakshman, Purinyl N1-directed aromatic C–H oxidation in 6-arylpurines and 6-arylpurine nucleosides, J. Org. Chem. 2013, 78, 7423–7435. §  M. K. Lakshman, A. Kumar, R. Balachandran, B. W. Day. G. Andrei, R. Snoeck, J. Balzarini, Synthesis and biological properties of C-2 triazolylinosine derivatives, J. Org. Chem. 2012, 77, 5870–5883. (Editor-selected featured article) §  M. K. Lakshman, A. C. Deb, R. R. Chamala, P. Pradhan, R. Pratap, Direct arylation of 6-phenylpurine and 6-arylpurine nucleosides by ruthenium-catalyzed C–H bond activation, Angew. Chem., Int. Ed. 2011, 50, 11400–11404. §  S. Bae, M. K. Lakshman, O6-(Benzotriazol-1-yl)inosine derivatives: easily synthesized, reactive nucleosides, J. Am. Chem. Soc. 2007, 129, 782–789.

Research Interests Keywords: Chemical Methodology, Metal catalysis, Nucleoside Modification, Biomolecules The program has many facets but can be broadly divided into the following areas. A. Development of New Chemical Methodology. B. Nucleoside modifications by new metal-catalyzed as well as novel uncatalyzed routes. B. Unusual applications of peptide coupling agents. C. Structural and biological effects of DNA modification by environmental pollutants. C. Novel reactions involving arynes. D. Development of new chemical methodology. Every aspect entails a detailed understanding of chemical process via mechanism studies involving techniques such as molecular spectroscopy, multinuclear NMR, and isotopic labeling.

Lakshman is an organic/bioorganic chemist with interests in: (a) new chemical methodology, (b) nucleoside modification by metal catalysis and uncatalyzed methods, (c) biological agents, (d) novel applications of peptide coupling agents, (e) new aryne reactions.

20008- current Professor 2004-2008 Associate Professor 2000-2004 Assistant Professor 1998-2000 Assistant Professor (U North Dakota) 1994-1997 Senior Scientist (Private Sector) 1990-1994 Fogarty Fellow NIH (HIDDK) 1985-1989 PhD

Dr Mahesh Lakshman

Themis Lazaridis Professor City College of New York Dept of Chemistry and Biochemistry 160 Convent Ave New York NY tlazaridis@ccny.cuny.edu http://www.sci.ccny.cuny.edu/~themis/

Publications Brice A., Lazaridis T. "Structure and Dynamics of a Fusion Peptide Helical Hairpin on the Membrane Surface: Comparison of Molecular Simulations and NMR", J. Phys. Chem. B, 118:4461-70 (2014) Lazaridis T., Versace R. "The treatment of solvent in multiscale biophysical modeling", Isr. J. Chem., 54:1074-83 (2014) Lazaridis T., Leveritt JM, PeBenito L. "Implicit membrane treatment of buried charged groups. Application to peptide translocation across lipid bilayers", BBA Biomembranes, 1838:2149-59 (2014) Prieto L., He Y., Lazaridis T. "Protein arcs may form stable pores in membranes", Biophys J, 106:154-161 (2014) Rahaman A., Lazaridis, T. "A thermodynamic approach to alamethicin pore formation", BBA Biomembranes 1838:98 (2014)

Research Interests My research is in the area of Theoretical and Computational Biophysical Chemistry, which aims to understand how biological systems work in terms of the fundamental laws of Physics and Chemistry. Biomolecules, such as proteins and nucleic acids, have well defined conformations which often change in the course of their function. Our goal is to understand the forces that operate within and between biomolecules and develop quantitative mathematical models for their energy as a function of conformation. Such models are useful in many ways, such as predicting the three-dimensional structure from sequence, characterizing conformational changes involved in biological function, or predicting the binding affinity between two biomolecules.

The Lazaridis lab works in the area of theoretical and computational Biophysics. In the past few years we have worked on the interaction of proteins with biological m e m b r a n e s . W e a r e especially interested in the process of pore formation by antimicrobial peptides and other toxins.

1998- City College 1992-1998 Postdoc, Harvard University 1987-1992 PhD, University of Delaware

Dr Themis Lazaridis

Jianbo Liu Associate Professor Queens College and the Graduate Center of CUNY Department of Chemistry and Biochemistry 65-30 Kissena Blvd. Queens, NY 11367 Jianbo.liu@qc.cuny.edu http://chem.qc.cuny.edu/~jliu/Liu_page/Liu_main.htm

Publications Fangwei Liu, Wenchao Lu, Yigang Fang, and J. Liu*, "Evolution of oxidation dynamics of histidine: Non-reactivity in the gas phase, peroxides in hydrated clusters, and pH dependence in solution", Phys. Chem. Chem. Phys. 2014, 16, 22179-22191. J. Liu*, Steven D. Chambreau, and Ghanshyam L. Vaghjiani, "Dynamics simulations and statistical modeling of thermal decomposition of 1-ethyl-3-methylimidazolium dicyanamide and 1-ethyl-2,3-dimethylimidazolium dicyanamide", J. Phys. Chem. A., 2014, 118, 11133-11144. Wenchao Lu, Fangwei Liu, Rifat Emre, and J. Liu*, "Collision dynamics of protonated N-acetyl methionine with singlet molecular oxygen (a1Dg): The influence of amide bond and ruling out the complex-mediated mechanism at low energies", J. Phys. Chem. B, 2014, 118, 3844-3852. Rui Sun, Matthew R. Siebert, Lai Xu, Steven D. Chambreau*, Ghanshyan L. Vaghjiani, Hans Lischka, Jianbo Liu*, and William L. Hase*, "Direct dynamics simulation of the activation and dissociation of 1,5-dinitrobiuret (HDNB)", J. Phys. Chem. A, 2014, 118, 2228-2236.   Research Interests

Keywords: mass spectrometry, singlet oxygen, reaction dynamics/kinetics, spectroscopy Our research focuses on using various instrumental analysis approaches (e.g., mass spectrometry, laser spectroscopy, and ion-molecule reactions) to probe biologically relevant processes in a spectrum of systems ranging from isolated biomolecules, through micelles and aerosols, to biomolecule solution. The experiments are complemented by extensive computational efforts including statistical modeling and dynamics simulations. We are also active in discovering and developing new instrumentation methods and nanotechnologies.

Physical Chemistry Analytical Chemistry Computational Chemistry Nanomaterials

2013- current Associate Professor, Queens College 2016-2013 Assistant Professor, Queens College 1999-2000 Postdoc, Lawrence Berkeley Lab 1997 Ph.D. (Physical Chemistry)

Dr. Jianbo Liu

Gustavo E. Lopez Professor Lehman College Department of Chemistry 250 Bedford Park Blvd West Bronx, NY gustavo.lopez1@lehman.cuny.edu

Publications (select) 1.  Effect of surface corrugation on low temperature

phases of adsorbed (p-H2)7 : A quantum path integral Monte Carlo study, Cruz, A., López, G.E. 2014, Phys. Lett. A, 378, 1375.

2.  The gamma-butyrolactone receptors BulR1 and BulR2 of Streptomyces tsukubaensis: tacrolimus (FK506) and butyrolactone synthetases production control, Salehi-Najafabadi, Z.; Barreiro, C; Rodriguez-Garcia, A.; Cruz, A.; Lopez, G.E.; Marin, J.F. 2014 Appl Microbiol Biotechnol, (DOI 10.1007/s00253-014-5595-9).

3.  Quinoline-2-thiol Derivatives as Fluorescent Sensors for Metals, pH, and HNO, 2014, O’Connor, N.A.; Lopez, G.E.; Cruz, A., Curr. Chem. Lett. (DOI 10.5267/j.ccl.2014.3.001).

4.  Src activation by β-adrenoreceptors is a key switch for tumour metastasis, Armaiz-Pena, G.N.; Allen, J.K.; Cruz, Anthony; Villares, G.J.; Cruz, A.; Stone, R.L.; Nick, A.M.; Lin, Y.G.; Han, L.Y.; Mangala, L.S.; Villares, G.J.; Vivas-Mejias, P.; Rodriguez-Aguayo, C.; Nagaraja, A.S.; Gharpure, K.M.; Wu, Z.; English, R.D.; Soman, K.V.; Shazhad, M.M.K.; Zigler, M.; Deavers, M.T.; Zien, A.; Soldatos, T.G.; Jackson, D.B.; Wiktorowicz, J.E.; Torres-Lugo, M.; Young, T.; Geest, K.D.; Gallick, G.E.; Bar-Eli, M.; López-Berestein, G.; Cole, S.W.; López, G.E.; Lutgendorf, S.K.; Sood, A.K., 2013, Nature Comm., 4, doi:10.1038/ncomms2413.

Research Interests Keywords: computational chemistry, path-integral Monte Carlo, molecular hydrogen, fluids, proton wires Professor Gustavo Lopez is interested in developing computational techniques to describe various systems in computational phase. Specifically, quantum and classical Monte Carlo techniques are applied to describe nanostructured systems, molecular hydrogen adsorbed on surface or trapped in fullerenes, and quantum liquids. Additionally, ab-initio techniques are used to describe molecular wires formed in helical peptides, metal oxides, and semiconductors

Gustavo Lopez is a Lehman College computational and theo re t i ca l chemis t . He specializes in developing and a p p l y i n g c o m p u t a t i o n a l methods to describe system in condensed phase. Some of the system considered are quantum fluids, proton wires, molecular hydrogen trapped in fullerenes, and biomolecular systems.

2010-present Professor, Lehman College 1994-2010 Professor, UPR-Mayaguez 1993-1994 Assistant Professor, IU-PR 1992-1994 Postdoc, U of Rhode Island 1986-1992 PhD, UMASS-Amherst

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Gustavo E. Lopez

Sharon Loverde Assistant Professor, Chemistry, College of Staten Island Graduate Center, Departments of Chemistry, Biochemistry, and Physics CUNY, College of Staten Island 2800 Victory Blvd, 6S-238 Staten Island, NY 10314 sharon.loverde@csi.cuny.edu https://sites.google.com/site/loverdelaboratory/

Publications Zhengyu Ma, D. N. Lebard *, S. M. Loverde *, K. A. Sharp, M. L. Klein, D. E. Discher, T. H. Finkel, Plos One, 11, e112292 (2014). Myungshim Kang and Sharon M. Loverde, Journal of Physical Chemistry B, 118, 11965-11972 (2014). Sharon M. Loverde, Journal of Physical Chemistry Letters, 5, 1669-1675 (2014). Sharon M. Loverde, Molecular Simulation, 40, 794-801 (2014). Wataru Shinoda, D. E. Discher, M. L. Klein, S. M. Loverde, Soft Matter, 9, 11549-11556 (2013).

Research Interests Keywords: Molecular dynamics, molecular self-assembly, polymer membranes, cellular membranes, multi-scale models, polymers/biopolymers

The Loverde laboratory utilizes all-atomistic (AA) a n d c o a r s e - g r a i n e d molecular dynamics (CG-M D ) s i m u l a t i o n s , i n combination with advanced sampling techniques, to i n v e s t i g a t e s o f t a n d biological materials.  

2012- current Assistant Prof. of Chemistry, Biochemistry, and Physics, College of Staten Island, CUNY

Dr. Sharon Loverde

Research Interests Keywords: superhydrophobicity, wetting, polymer pen printing, photocatalysis, thermal interfaces Using natural surfaces as inspiration, the Lyons group fabricates nanoscale materials with unique wetting, catalytic, thermal and/or optical properties. We are especially interested in developing a fundamental understanding of reactions and properties at the solid-liquid-gas interface. We work closely with industry with the goal of transitioning our inventions into industrially relevant innovations; active projects include: anti-reflective self-cleaning optically clear coatings to increase the energy efficiency of photovoltaic panels and the isolation and study of single cells within nano/picoliter gel droplet arrays.

Dr Alan Lyons Alan Lyons is Professor of Chemistry at the College of Staten Island and Graduate Center of CUNY. His research is focused on the effect of topography and chemistry on the wetting, thermal, optical and catalytic properties of surfaces.

Publications Y. Zhao, Y. Liu, QF Xu, M. Barahman, A.M. Lyons, A Catalytic, Self-Cleaning Surface with Stable Superhydrophobic Properties: Printed PDMS Arrays Embedded with TiO2 Nanoparticles, ACS Appl. Mater. Interfaces, 2015, 7 (4), pp 2632–2640.

Z. Mao, M. Ganesh, M. Bucaro, I. Smolianski, R.A. Gross, A.M. Lyons, A High Throughput, High Resolution Enzymatic Lithography Process: Effect of Crystallite Size, Moisture and Enzyme Concentration, Biomacromolecules, 2014, 15 (12), 4627-4636. D. Aebisher, D. Bartusik, Y. Liu, Y. Zhao, M. Barahman, Q.F. Xu, A.M. Lyons, A. Greer, Superhydrophobic Photosensitizers. Mechanistic Studies of 1O2 Generation in the Plastron and Solid/Liquid Droplet Interface, J. Am. Chem. Soc., 2013, 135, 18990–1899. Q.F. Xu, B. Mondal, and A.M. Lyons, Fabricating Superhydrophobic Polymer Surfaces with Excellent Abrasion Resistance by a Simple Lamination Templating Method, ACS Appl. Mater. Interfaces, 2011, 3, 3508–3514. R. Kempers, A.M. Lyons, A.J. Robinson, Modeling & Characterization of Metal Micro-Textured Thermal Interface Materials, ASME J. Heat Transfer, 2013, 136, 01130.

Dr. Alan M. Lyons Professor College of Staten Island and Graduate Center CUNY Room 62-225 2800 Victory Boulevard Staten Island, NY 10314 Email.alan.lyons@csi.cuny.edu http://csivc.csi.cuny.edu/Alan.Lyons/files/

2008- current Professor, Department of Chemistry, College of Staten Island & Graduate Center CUNY.

1980-2008 Distinguished Member of Technica Staff, Manager & Group Leader Bell Laboratories, Murray Hill NJ

1981- 1987 PhD, MS, Polymer Chemistry NYU-Poly

Prabodhika Mallikaratchy Assistant Professor Lehman College 250 Bedford Park Boulevard West Bronx,10468 NY prabodhika.mallikaratchy@lehman.cuny.edu http:/ /www.lehman.edu/academics/chemistry/prof_mallikaratchy.php

Publications Prabodhika Mallikaratchy, Zumrut, Hasan, Ara, Naznin “Discovery of Biomarkers Using Aptamers Evolved in Cell-SELEX Method”, Aptamers selected by cell-SELEX for Theranostics” Principles, Eds. W. Tan and X. Fan, SpringerLink. 2015; p.265. Prabodhika Mallikaratchy, Jeffery Gardner, Lars Ulrik R. Nordstrøm, Nicholas J. Veomett, Michael R. McDevitt, Mark L. Heaney, and David A. Scheinberg.Nucleic Acid Therapeutics. 2013, 23(4): 289-299. doi:10.1089/nat.2013.0425. Prabodhika R. Mallikaratchy, Alessandro Ruggiero, Jeffrey R. Gardner, Vitaly Kuryavyi, William F. Maguire, Mark L. Heaney, Michael R. McDevitt, Dinshaw J. Patel and David A. Scheinberg. “A multivalent DNA aptamer specific for the B cell receptor on human lymphoma and leukemia” Nucleic Acids Res. 2011; 39(6): 2458. Tang Z., Zhu Z., Mallikaratchy P., Yang R., Sefah K., Tan W. “Aptamer-target binding triggered molecular mediation of singlet oxygen generation” Chem. Asian J. 2010; 5 (4): 783.

Research Interests Keywords: DNA aptamers, Cell-SELEX technology, DNA nanotechnology Long-term goal of this laboratory is to develop oligonucleotide aptamer based synthetic antibodies for biological and biomedical applications. Therefore, this research program is aimed at generating new aptamers against biologically important cellular targets, and molecular engineering of multifunctional aptamer structures suitable for drug delivery.  

The Mallikaratchy group focuses on developing DNA aptamers as therapeutics, Cell-SELEX technology and DNA nanotechnology

2010- Present Assistant Professor, Lehman College- CUNY

2008-2010 Assistant Professor, San Jose State Univ. 2003-2007 PhD, University of Florida, Gainesville

Dr. Prabodhika Mallikaratchy

Hiroshi Matsui Professor Hunter College 695 Park Avenue, New York, NY 10065 lmassa@hunter.cuny.edu http://www.hunter.cuny.edu/chemistry/faculty/Lou/Lou

Publications Dielectric Response of High Explosives at THz Frequencies Calculated by Density Functional Theory, Lulu Huang, Andrew Shabaev, Sam Lambrakos, Noam Bernstein, Vern Jacobs, Dan Finkenstadt, Lou Massa, Journal of Materials Engineering and Performance (2012) 21(7), 1120-1132.

The Kernel Energy Method: Application to Graphene and Extended Aromatics, Lulu Huang, Hugo Bohorquez, Cherif F. Matta and Lou Massa, IJQC, Vol. 111, 15, 4150-4157 (2011) The Kernel Energy Method: Construction of 3 & 4 tuple Kernels from a List of Double Kernel Interactions, Lulu Huang, Lou Massa, Journal of Molecular Structure: THEOCHEM, Vol. 962, issue 1-3, 72-79 (2010) Calculation of Strong and Weak Interactions in TDA1 and RangDP52 by Kernel Energy Method, Huang, L.; Massa, L.; Karle, I.; Karle, J. Proceedings of the National Academy of Sciences, Vol. 106, No. 10, 3664-3669 (2009) The Kernel Energy Method of Quantum Mechanical Approximation carried to Fourth Order Terms, Huang, L.; Massa, L.; and Karle, J. PNAS, Vol. 105, No. 6, 1849-1854 (2008)

Research Interests Keywords: differential equations, density matrices, density functional theory, Xray crystallography, kernel energy method, information theory, Applications of Quantum Mechanics to the electronic structure of atoms, molecules, and solids.

Postdoc: Brookhaven National Laboratory PhD: Theoretical Molecular Physics, Georgetown University

Dr. Louis Massa

Hiroshi Matsui Professor Hunter College / Weill Medical College of Cornell U 413 E. 69th Street Belfer Research Building New York, NY 10021 hmatsui@hunter.cuny.edu www.hunter.cuny.edu/chemistry/faculty/Hiroshi/Hiroshil

Publications “Rational strategy for shaped nanomaterial synthesis in reverse micelle reactors”, Z. Wei, H. Matsui, Nature Commun., 5, 3870, (2014). “Impedimetric Detection of Mutant p53 Biomarker-Driven Metastatic Breast Cancers under Hyposmotic Pressure”, M. Shi, N. Shtraizent, A. Polotskaia, J. Bargonetti, H. Matsui, PloSOne, 9(6): e99351., DOI: 10.1371/journal.pone.0099351 (2014). “Biocatalytic Self-Assembly Enables Discovery of Catalytic Peptides by Phage Display”, Y. Maeda, N. Javid, K. Duncan, L. Birchall, K. Gibson, D. Cannon, Y. Kanetsuki, C. Knapp, T. Tuttle, R.V. Ulijn, H. Matsui, J. Am. Chem. Soc., 136, 15893-15896 (2014). “Peptide Assembly-Driven Metal-Organic Framework (MOF) Motors for Micro Electric Generators”, Y. Ikezoe, J. Fang, T.L. Wasik, T. Uemura, Y. Zheng, S. Kitagawa, H. Matsui, Adv. Mater., 27, 288-291 (2014). “Label-free cancer cel l detect ion with impedimetric transducers”, R. de la Rica, S, Thompson, A. Baldi, C. Fernández-Sánchez, C.M. Drain, and H. Matsui, Anal. Chem., 81, 10167 (2009). (featured as research news in the N a t i o n a l C a n c e r I n s t i t u t e i n 2 0 0 9 , http:/ /physics.cancer.gov/news/2009/dec/po_news_e.asp)

Research Interests Keywords: Cancer Nanotechnology, Cancer Diagnostics/therapeutics, Lab-On-a-Chip, Medical Nanoparticles 1.  Study of the effect on cellular structure by cancer metastasis. 2.  Analysis of nanoscale vesicles released from cancer cells for diagnostics and therapeutics. 3.  Electric silicon chip microfabrication for the detection of cancer and related cells. 4.  Synthesis of nanoparticles in complex shapes for medical applications such as MRI contrast agents and drug delivery.

Matsui is a Professor at Hunter College and Weill Medical College of Cornell University. My research a r e a s a r e C a n c e r diagnostics/ therapeutics, Bionanotechnology, Lab-On-a-Chip, and Nanoparticle Synthes is for Medica l Applications.

2001- current Current position 1996-1999 Columbia University, Postdoc 1992-1996 Purdue University, PhD 1991-1992 Stanford University, MS

Dr. Hiroshi Matsui

Dr. Aneta Mieszawska Assistant Professor, Nanomedicine Department of Chemistry Brooklyn College 2900 Bedford Avenue Brooklyn, New York NY ACzajkowska@brooklyn.cuny.edu www.cuny.edu/web/academics/faculty

Publications Mieszawska AJ, Kim Y, Gianella A, van Rooy I, Priem B, Labarre MP, Ozcan C, Cormode DP, Petrov A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ.; “Synthesis of polymer-lipid nanoparticles for image-guided delivery of dual modality therapy” Biocojug Chem. 2013, PMID 23957728. Gianella A, Mieszawska AJ, Hoeben FJ, Janssen HM, Jarzyna PA, Cormode DP, Costa KD, Rao S, Farokhzad OC, Langer R, Fayad ZA, Mulder WJ. “Synthesis and in vitro evaluation of a mul t i funct ional and surface-swi tchable nanoemulsion platform.” Chem Commun. 2013 PMID 23877789. Mieszawska AJ, Mulder WJ, Fayad ZA, Cormode DP.; “Multifunctional gold nanoparticles for diagnosis and therapy of disease” Mol. Pharm. 2013, PMID 23360440. Mieszawska AJ, Gianella A, Cormode DP, Zhao Y, Meijerink A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ.; “Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging” Chem. Commun. 2012, PMID 22555311. Research Interests

Keywords: second generation nanoparticles, theranostics, biodegradable polymers, nanocrystals The Mieszawska group research focuses on nanotechnology and nanomedicine with specific interest in designing and testing the nanoparticle systems for concurrent imaging and therapy of disease. These theranostic nanoparticles are based on slow releasing biodegradable and biocompatible polymers, such as PLGA or PLA, that encapsulate contrast agents and small drug molecules. The primary goal is to target and deliver efficacious therapy directly to cancer cells. This interdisciplinary research involves active collaboration with clinicians from Icahn School of Medicine at Mount Sinai.

Aneta Mieszawska is an Assistant Professor in the Department of Chemistry at Brooklyn Col lege. Her research is focused on n a n o m e d i c i n e a n d application of nanoparticle based systems for cancer detection and treatment.

2013- current Assistant Professor, Brooklyn College 2011-2013 Postdoctoral Fellow, Icahn School of Medicine at Mount Sinai 2007-2010 Postdoctoral Associate, Tufts University 2002-2007 PhD University of Louisville

Dr. Aneta Mieszawska

Michael V. Mirkin Professor of Chemistry CUNY-Queens College 65-30 Kissena Blvd Flushing, NY 11367 mmirkin@qc.cuny.edu http://chem.qc.cuny.edu/~mirkinlab/mvm.html

Publications Nanoelectrochemistry, ed. M.V. Mirkin and S. Amemiya, CRC Press, Boca Raton, FL, 2015 Scanning Electrochemical Microscopy, ed. A.J. Bard and M.V. Mirkin, CRC Press, Boca Raton FL, 2nd edition, 2012. T. Sun, Y. Yu, B.J. Zacher and M.V. Mirkin, Scanning Electrochemical Microscopy of Individual Catalytic Nanoparticles, Angew. Chem. Int. Ed. 2014, 53, 14120 –14123 (VIP article). Y.X. Wang, T. Kakiuchi, Y. Yasui, and M.V. Mirkin, Kinetics of Ion Transfer at the Ionic Liquid/Water Nanointerface, JACS, 2010, 132, 16945-16952. J. Velmurugan, D. Zhan, and M.V. Mirkin, Electrochemistry through Glass, Nature Chem. 2010, 2, 498-502. P. Sun and M.V. Mirkin, Electrochemistry of individual molecules in zeptoliter volumes, JACS, 2008, 130, 8241-8250. P. Sun, F.O. Laforge, T.P. Abeyweera, S.A. Rotenberg, J. Carpino, and M.V. Mirkin, Nanoelectrochemistry of mammalian cells, PNAS, 2008, 105, 443-448.

Research Interests Keywords: Electrochemistry/Physical/Analytical/Nano We employ nanometer-sized electrochemical probes for molecular level characterization of chemical processes and materials. A wide variety of phenomena are studied including charge-transfer reactions at the solid/liquid and liquid/liquid interfaces, electrocatalysis, bioelectrochemistry, and electrochemical imaging. The main focus is on obtaining quantitative physico-chemical information by combination of experiments with mathematical modeling and computer simulations. We also maintain active interest in development of electrochemical techniques for analytical applications. These include carbon nanoprobes, amperometric nanosensors, and resistive-pulse sensors.

Michael V. Mirkin is a professor of chemistry at CUNY-Queens College. His research interests are in the field of electrochemistry and include nano- and bio-electrochemistry, interfacial charge-transfer reactions, e l e c t r o c a t a l y s i s , a n d scanning electrochemical microscopy (SECM).

1993 - current Professor of Chemistry 1990-1993 Postdoc, University of Texas at Austin 1982-1987 PhD in Electrochemistry, Kazakh State

University, USSR.

Dr. Michael V. Mirkin

David Mootoo Professor Hunter College Chemistry Department 695 Park Avenue New York NY 10065 dmootoo@hunter.cuny.edu http://www.hunter.cuny.edu/chemistry/faculty/Randy/Randy

Publications Garg, H.; Francella, N.; Tony, K. A.; Augustin, L. A.; Fantini, J.; Barchi Jr, J. J.; Puri, A.; Mootoo; Blumenthal, R. Glycoside analogues of a-galactosylceramide, a novel class of small molecule inhibitors for HIV-1 entry. Antiviral Res. 2008 80, 54-61. Hans, S. K.; Camara, F.; Martin-Montalvo, A.; Brautigan, D. L.; Heimark, D.; Larner, J.; Grindrod, S.; Brown, M.; Mootoo, D. R. Synthesis of the C-glycoside analog of b-galactosamine-(1->4)-3-O-methyl-D-chiro-inositol and assay as activator of protein phosphatases PDHP and PP2Ca. Bioorg. Med. Chem. 2010, 18, 1103-1110. Bachan, S.; Fantini, J.; Joshi, A.; Garg, H.; Mootoo, D. R. Synthesis, gp120 binding and anti-HIV activity of fatty acid esters of 1,1-linked disaccharides. Bioorg. Med. Chem. 2011, 19, 14803-14811. Bachan, S.; Tony, K. A.; Kawamura, A.; Montenegro, D.; Joshi, A.; Garg, H.Synthesis and anti-tumor activity of carbohydrate analogues of the tetrahydrofuran containing acetogenins. Bioorg. Med. Chem. 2013, 21, 6554-6564. Intramolecular nitrogen delivery for the synthesis of C-glycosphingolipids. Altiti, A. S.; Mootoo, D. R. Application to the C-Glycoside of the immunostimulant KRN7000. Org. Lett, 2014, 16, 1466-1469.

Research Interests Keywords:synthesis, glycomimetics, tumor targeting, immunostimulants An broad area of current interest is the design and synthesis of molecules for interrogating anti-cancer pathways. Two strategies that center on targeting cytotoxic agents to tumors and glycolipids that boost the immune system against cancer are being pursued. These projects entail the design and synthesis of novel small molecules and examination of their biological properties, in the context of specific disease mechanisms.

Our research centers o n t h e d e s i g n , s y n t h e s i s a n d a p p l i c a t i o n o f b i o m e c h a n i s t i c p r o b e s , a n d t h e development of new s y n t h e t i c methodologies.

1989- current Professor 1986-1989 Postdoc, Duke University 1982-1986 Ph.D., University of Maryland

Dr. David R. Mootoo

Ryan P. Murelli Assistant Professor Brooklyn College 2900 Bedford Avenue Brooklyn, NY rpmurelli@brooklyn.cuny.edu http://userhome.brooklyn.cuny.edu/rpmurelli/

Publications Lu, G.; Lomonosova, E.; Cheng, X.; Moran, E. A.; Meyers, M. J.; Le Grice, S. F. J.; Thomas, C. J.; Jiang, J-K.; Meck, C.; Hirsch, D. R.; D'Erasemo, M. P.; Suyabatmaz, D. M.; Murelli, R. P.; Tavis, J. E. "Hydroxylated tropolones inhibit hepatitis B virus replication by blocking the viral ribonuclease H activity" Antimicrob. Agents Chemother. 2015, 59, 1070-1079. Hirsch, D. R.; Cox, G. C.; D'Erasmo, M. P.; Shakya, T.; Meck, C.; Mohd, N.; Wright, G. D.; Murelli, R. P. "Inhibition of ANT(2")-Ia resitance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones" Bioorg. Med. Chem. Lett. 2014, 24, 4943-4947. Meck, C.; D' Erasmo, M. P.; Hirsch, D. R.; Murelli, R. P. "The biology and synthesis of α-hydroxytropolones" Med. Chem. Comm. 2014, 5, 842-852.

Williams, Y. D.; Meck, C.; Mohd, N.; Murelli, R. P. "Triflic acid mediated rearrangements of 3-methoxy-8-oxabicyclo[3.2.1]octa-3,6-dien-2-ones: Synthesis of methoxytropolones and furans" J. Org. Chem. 2013, 78, 11707-11713. Meck, C.; Mohd, N.; Murelli, R. P. "An oxidopyrylium cyclization/ ring-opening route to polysubstituted α-hydroxytropolones" Org. Lett. 2012, 14, 5988-5991.

Research Interests Keywords: Synthetic Organic Chemistry, Medicinal Chemistry, Chemical Biology Our mission is to make fundamental contributions to synthetic organic chemistry, biology and medicine. To accomplish this, we seek out problems in medicinal chemistry and chemical biology that are in need of new synthetic organic chemistry developments. Thus, primary studies carried out by lab members range from reaction discovery and mechanism investigations to multi-step synthetic strategy developments. We simultaneously partner with experts in complementary fields in order to leverage these advancements in a broad range of interdisciplinary projects devoted to lead drug discovery and development.

2010- current Assistant Professor, Boston College 2007-2010 Postdoctoral Associate, Yale University 2002-2007 PhD Student, Boston College

Dr. Ryan Murelli Dr. Murelli is a trained synthetic organic chemist with interests in reaction d e v e l o p m e n t , t o t a l s y n t h e s i s , m e d i c i n a l chemistry and chemical biology. His primary research interest involves troponoids as therapeutic targets and is developing drugs for HIV, Herpes Simplex Virus Hepatitis B, and many more.

Naphtali O’Connor Assistant Professor Lehman College, CUNY 250 Bedford Park Blvd West Bronx, NY 10468 Naphtali.oconnor@lehman.cuny.edu lehman.edu/academics/chemistry/prof-oconnor.php

Publications O’Connor, N.A.; Abugharbieh, A.; Buabeng, E.; Yasmeen, F.; Mathew, S.; Samaroo, D.; Cheng, H. “The Crosslinking of Polysaccharides with Polyamines and Dextran-Polyallylamine Antibacterial Hydrogels” Int. J. Biol. Macromol. (2015) 72, 88-93. Samaroo, D.; Perez, E.; Aggarwal, A.; Wills, A.; O’Connor, N.A. “Strategies for Delivering Porphyrinoid-based Photosensit izers in Therapeutic Applications” Therapeutic Delivery (2014), 5(7), 859-872.

Solomon, M.R.; O’Connor, N.A.; Paik, D.C.; Turro, N.J. “Nitroalcohol Induced Hydrogel Formation in Amine-Functionalized Polymers.” J. Appl. Polym. Sci. (2010), 117(2), 1193-1196. O'Connor, N.A.; Stevens, N.; Samaroo, D.; Solomon, M.R.; Martí, A.A.; Dyer, J.; Vishwasrao, H.; Akins, D.L.; Kandel, E.R.; Turro, N.J. “A covalently linked phenanthridine-ruthenium(II) complex as a RNA probe.” Chem. Comm. (2009), 2640-2642. Stevens, N.; O'Connor, N.A.; Vishwasrao, H.; Samaroo, D.; Kandel, E.R.; Akins, D.L.; Drain, Charles M.; Turro, N.J. “Two color RNA intercalating probe for cell imaging applications.” J. Am. Chem. Soc. (2008) 130, 7206-7207. Research Interests

Keywords: biomaterials, hydrogels, polymers My current research focus is the development of materials for biomedical applications. We recently developed a method for preparing polysaccharide-polyamine crosslinked hydrogels. We are currently exploring their application as anti-microbial and wound healing materials. We are also working on the development of curcumin based biomaterials as antibacterial agents and cancer therapeutics.

Naphtali has a varied research background that reflects his wide research interests. His research ranges from developing biomaterials to designing molecular probes.

2008- current Current position 2007-2008 Postdoc/Columbia University 2000-2006 PhD/University of California, Irvine

Dr. Naphtali O’Connor

Ralf M. Peetz, PhD Assoc. Prof. CUNY/ Staten Island and Graduate Center 2800 Victory Boulevard Building 6S-227 Staten Island, NY 103014 ralf.peetz@csi.cuny.edu http://www.csi.cuny.edu/departments/chemistry

Publications Sengupta, Arijit; Doshi, Ami; Jaekle, Frieder; Peetz, Ralf M., Journal of Polymer Science Part A (2015), accepted

Zhilin, Denis M.; Peetz, Ralf M., Journal of Chemical Education (2014), 91(1), 119-122 Sengupta, Arijit; Ghosh, Sutapa; Peetz, Ralf M., Synthetic Metals (2010), 160(17-18), 2037-2040 Burrows, Hugh D.; Narwark, Oliver; Peetz, Ralf; Thorn-Csanyi, Emma; Monkman, Andrew P.; Hamblett, Ian; Navaratnam, Suppiah, Photochemical & Photobiological Sciences (2010), 9(7), 942-948. M u k h e r j e e , N a r a y a n ; P e e t z , R a l f M . , Macromolecules (2008), 41(18), 6677-6685

Research Interests Keywords: Functional Materials, Conjugated Polymers, Donor Acceptor Systems We are currently interested in the controlled synthesis of donor-acceptor macromolecules for potential use in organic polymer photovoltaics. Some candidates featuring promising electronic properties and absorbing over a broad range of wavelengths are currently scheduled to be tested in prototype photovoltaic cells.

Ralf Peetz is interested in functional materials that could be of use in meeting future energy needs.

2003- current CSI and Graduate Center 2000-2003 Postdoc, University of Akron, Institute

of Polymer Science 1997-2000 PhD, University of Hamburg,

Germany

Dr. Ralf M. Peetz

Sébastien Poget Assistant Professor College of Staten Island, CUNY Department of Chemistry 2800 Victory Blvd. Staten Island, NY 10314 sebastien.poget@csi.cuny.edu www.csi.cuny.edu/faculty/POGET_SEBASTIEN.html

Publications P. Anand, A. Grigoryan, M. H. Bhuiyan, B. Ueberheide, V. Russell, J. Quinoñez, P. Moy, B. T. Chait, S. F. Poget, M. Holford: Sample limited characterization of a novel disulfide-rich venom peptide toxin from terebrid marine snail Terebra variegata. PLoS ONE 2014, 9, e94122. S. F. Poget, M. E. Girvin: Solution NMR of membrane proteins in bilayer mimics: Small is beautiful, but sometimes bigger is better. Biochim. Biophys. Acta 2007, 1768, 3098-106. S. F. Poget, S. M. Cahill, M. E. Girvin: Isotropic bicelles stabilize the functional form of a small multidrug-resistance pump for NMR structural studies. J. Am. Chem. Soc. 2007, 129 2432-2433.

Research Interests Keywords: Solution-state NMR, membrane protein structural biology, ion channels, toxins, electrophysiology, biophysics The Poget lab is interested in the structural and functional study of membrane proteins through solution-state NMR and other biophysical methods. Our studies focus on better understanding the interactions of animal peptide toxins with their target ion channel domains as tools for an improved understanding of ion channel function and starting point for drug development. To carry out these studies at the cutting edge of structural biology, we are also involved in the development of new and improved methods for membrane protein studies, including development of more powerful membrane mimetics such as bicelles and optimized NMR methods.

Dr. Poget is interested in membrane protein structure a n d f u n c t i o n , w i t h a particular emphasis on the interactions between ion channe l domains and animal peptide toxins.

2009- current Assistant Professor, College of Staten Island, CUNY

2003-2009 Postdoc, Albert Einstein College of Medicine, NY

2001-2003 Postdoc, Rockefeller University, NY 1997-2001 PhD, University of Cambridge, UK

Dr. Sébastien Poget

Adam A. Profit, Ph.D. Associate Professor York College 94-20 Guy R. Brewer Blvd Jamaica, NY 11451 Email.aprofit@york.cuny.edu www.york.cuny.edu/portal_college/aprofit

Publications Profit, A. A., Vedad, J. Saleh, M., and Desamero, R.Z.B. “Aromaticity and Amyloid Formation: Effect of π-Electron Distribution and Aryl Substituent Geometry on the Self-Assembly of Peptides Derived from hIAPP22-29” Arch Biochem Biophys 2015, 567, 46-58. Profit, A. A., Felsen, V., Chinwong, J., Mojica, E-R., and Desamero, R.Z.B. “Evidence of π-stacking Interactions in the Self-assembly of hIAPP22-29” PROTEINS: Structure, Function and Bioinformatics 2013, 81, 690-703.

Research Interests Keywords: Amyloid, protein kinases, peptides, peptoids, enzymology, solid phase synthesis The abnormal formation of protein aggregates, or amyloid deposits, is the hallmark of Alzheimer’s disease as well as type 2 diabetes. My laboratory is investigating the molecular interactions that occur between key proteins that contribute to the formation of amyloid in these diseases. Through a more detailed understanding of how these proteins self-assembly to form aggregates, we hope to design and develop small molecule and peptide mimetic inhibitors which may serve as potential therapeutic agents.

We are also developing compounds that inhibit the activity of key enzymes (kinases) which can cause tissues to grow out of control and develop into tumors. To accomplish this we are synthesizing molecules that exploit the unique molecular recognition motifs found in these enzymes to more effectively deliver inhibitory species to the active site.

Protein-ligand interactions is the unifying theme of my research in terests . In part icular, the design, synthesis and application of biologically relevant probe molecules to study and elucidate protein-protein and protein-ligand interactions involved in amyloid diseases and cancer.

2014- current Associate Professor of Chemistry 2004-2014 Assistant Professor of Chemistry 2000-2004 Merck Research Laboratories 1997-2000 Postdoc - Albert Einstein College of Medicine 1997 PhD - Stony Brook University

Dr. Adam A. Profit

Krishnaswami Raja, Ph.D. Associate Professor College of Staten Island Department of Chemistry 2800 Victory Boulevard Staten Island, New York 10314 Krishnaswami.Raja@cuny.edu h t t p : / / w w w . c s i . c u n y . e d u / f a c u l t y /RAJA_KRISHNASWAMI.html

Publications

“Curcumin-derived green plasticizers for Poly(vinyl) chloride.” Saltos, J., Shi, W.; Mancuso, A, Park, T.; Averick, N.; Sun, C.; Fata, J. E.;. Punia, K.; Raja, K. S.* RSC Adv., 2014, 4 (97), 54725 – 54728. Raja, K.S. Editorial: Green Anti-Cancer Agents and Ayur-Biotechnology: A smart approach towards improving R&D productivity. Anticancer Agents in Med Chem 2013 Dec;13(10):1467-8. Raja, K.S.; Banerjee, P.; Lamoreaux, W.; Shi, W.; A u e r b a c h , A . ;“N o v e l C u r c u m i n a n d Tetrahydrocurcumin derivatives” US patent number 8487139 Dolai, S. ; Shi, W.; and Raja, K.S.“Synthesis of Drug/Dye-Incorporated Polymer–Protein Hybrids” Methods in Molecular Biology Bioconjugation Protocols : Strategies and Vol 751, 29-42, 2011. Raja, K.S., Dolai, S. ; Shi, W.; Wang, Q. Bionanoparticles as nanoscaffolds for chemical manipulation”. Encyclopedia of Nanoscience and Nanotechnology, Marcel Dekker, 2009, Second Edition.

Research Interests Keywords: Origin of life, stigmergy scaffolds, 3D Cell culture, Ayurbiotecnology, Virus Chemistry, Bioconjugation, Green drug development, Polymer-protein hybrids The Raja group is interested in creating programmable scaffolds for probing the origins of multi-cellular life, synthesis of well defined polymer-bionanoparticle/targeting protein hybrids and green drug discovery and development based on Ayurveda. The research spans the areas of small molecule and polymer synthesis, bioconjugation chemistry and bioengineering.

Krishnaswami Raja is College of Staten Island Chemistry faculty working in t h e a r e a o f Bionanotechnology, Origin of life research and green d r u g d i s c o v e r y a n d development.

2012- current Associate Professor 2005-2012 Assistant Professor, College of Staten

Island 2000-2004 Skaggs Post Doctoral Fellow TSRI 1999 Indian Institute of Science

Dr. Krishnaswami Raja

Name: Varattur D. Reddy Position : Professor Affiliation: Kingsborough Community College Address: 2001 Oriental Blvd Manhattan Beach, Brooklyn, NY 11235 vreddy@kbcc.cuny.edu and vreddy@gc.cuny.edu

Publications 1.    Reddy,  V.  D.,  Greener  Organic  Chemistry  Experiments:  A  Miniscale  and  Microscale  Approach  3rd  Edi:on,  John  Wiley  &  Sons,  2015.  2.      Reddy,  V.  D.  Organometallic  AnL-­‐cancer                Complexes”.  U.S.  Pat.  2012/032507  and                Int.  Pat.  WO  2012/138988  A2.  3.      Reddy,  V.  D.;  Dayal,  D.;  Szalda,  D.J.    

 Cosenza,  S.C.;  Reddy,  M.V.R.  “  Synthesis,    structures,  and  anLcancer  acLvity  of  novel  Organometallic  ruthenium-­‐maltol    complexes”.    J.  Organomet.  Chem,  2012,  700,  180.  4.      Reddy,  V.  D.;  Dayal,  D.;  Cosenza,  S.C.;  Reddy.  M.V.  R.;  Pearl.  Jr.,  W.C.;  Adams,  R.D.  “Glycal  ruthenium  carbonyl  clusters:  Synthesis,  characterizaLon,  and  anLcancer  acLvity,” J.Organomet.  Chem,  2009,  694,  959.  5.        Reddy,  V.  D.  “Synthesis,  characterizaLon,                  and  reacLvity  of  a  novel  ruthenium  carbonyl  cluster  containing  tri-­‐O-­‐benzyl-­‐D-­‐glucal  as  a  chiral  carbohydrate  ligand,” J.  Organomet.  Chem,  2006,  691,  27.  6.      Reddy,  V.D.;  Franck,  R.W.  “Cleavage  and  AcLvaLon  of  Benzylidene  Lactones  with                    N-­‐Bromosuccinimide,” J.  Org.  Chem.                    1993,  58,  6911.   Research Interests

 Synthesis  of  organic  and  organometallic  compounds  as  anLcancer  and  anL-­‐Alzheimer's  disease  agents.   Organic   synthesis   involves   total   synthesis   of   natural   and   unnatural   products   and  modified  carbohydrates.  Organometallic  chemistry  involves  synthesis  of  novel  organometallic  catalysts,   efficient   methodologies   for   the   synthesis   of   biologically   acLve   molecules,  bioorganometallics,   and   drug   delivery   systems.   Research   faciliLes   at   Kingsborough   are   400  MHz  NMR  Facility,  IR,  GC,  and  HPLC.

Our group research focuses on the following areas: Synthesis of o rgan ic and o rganometa l l i c compounds as anticancer and anti-Alzheimer’s disease agents, and catalysis.

2001- current Kingsborough Community College-CUNY 1993-2001 Schering Plough Pharmaceutical Company currently Merck and American Health Foundation 1990-1993 Hunter College and Queens College 1990 Ph.D. Indian Institute of Technology, Mumbai

Dr. Varattur Reddy

CUNY  by  the  Sea  

Kevin Ryan, Ph.D. Associate Professor, Biochemistry Division Department of Chemistry and Biochemistry The City College of New York MR-1337, 160 Convent Ave. New York NY kr107@sci.ccny.cuny.edu http://www.sci.ccny.cuny.edu/~kr107/index2/index.html

Publications Liu, M. T.; Nagre, N. N.; Ryan, K., Structurally diverse low molecular weight activators of the mammalian pre-mRNA 3' cleavage reaction. Bioorganic & Medicinal Chemistry 2014, 22 (2), 834-41; Li, Y.; Peterlin, Z.; et al., Aldehyde Recognition and Discrimination by Mammalian Odorant Receptors via Functional Group-Specific Hydration Chemistry. ACS Chemical Biology 2014; Lama, L.; Seidl, C. I.; Ryan, K., New insights into the promoterless transcription of DNA coligo templates by RNA polymerase III. Transcription 2014, 5 (1); Seidl, C. I.; Lama, L.; Ryan, K., Circularized synthetic oligodeoxynucleotides serve as promoterless RNA polymerase III templates for small RNA generation in human cells. Nucleic Acids Research 2013, 41 (4), 2552-64; Kurland, M. D.; Newcomer, M. B.; et al., Discrimination of saturated aldehydes by the rat I7 olfactory receptor. Biochemistry 2010, 49 (30), 6302-4.

Research Interests Keywords: molecular recognition, olfaction, RNA, micro RNA, RNA interference, RNA polymerase III, chemical biology, transcription In the RNA area, we study the use of chemically synthesized transcription templates as potential information-bearing molecules for producing small therapeutic RNA in human cells. A second RNA area is the biochemistry of RNA processing reactions that occur during the biogenesis of messenger RNA in human cells. In the olfaction area, we use pharmacology, organic synthesis and chemical biology to probe the biochemistry of the sense of smell.

Dr. Ryan’s lab applies chemica l concep ts to biological problems in two main areas, RNA and o l f a c t o r y m o l e c u l a r recognition.

2009- current Associate Professor 2003-2008 Assistant Professor 1996-2003 Postdoc, Columbia University (Chemistry

and Biology Depts.) 1996 Ph.D., University of Rochester

Dr. Kevin Ryan

Chwen-Yang Shew Professor Department of Chemistry College of Staten Island 2800 Victory Boulevard Staten Island, NY 10314 chwenyang.shew@cuny.edu

Publications C.-Y. Shew, and K. Yoshikawa, “A toy model for nucleus-sized crowding confinement “J. Phys.: Condens. Matter 27 (2015) 064118. E. Sánchez-Díaz, C.-Y. Shew, X. Li, B. Wu, G. S. Smith and W.-R. Chen, “Phase Behavior Under a Noncentrosymmetric Interaction: Shifted-Charge Colloids Investigated by Monte Carlo Simulation,” J. Phys. Chem. B, 118 (2014) 6963–6971. C.-Y. Shew, K. Kondo and K. Yoshikawa, “Rigidity of a spherical capsule switches the localization of encapsulated particles between inner and peripheral regions under crowding condition: Simple model on cellular architecture,” J. Chem. Phys. 140 (2014) 024907. C.-Y. Shew and K. Yoshikawa, “Abstracting the essence of the confinement effect on crowding microspheres: Mean-field theory and numerical simulation,” Chem. Phys. Lett. 590 (2013) 196-200. C.-Y. Shew, C. Do, K. Hong, Y. Liu, L. Porcar, G. S. Smith, and W.-R. Chen,“ Conformational effect on small angle neutron scattering behavior of interacting polyelectrolyte solutions: A perspective of integral equation theory,” J. Chem. Phys. 137 (2012) 024907. Research Interests

Keywords: Statistical Mechanics, Computer Simulations, Soft Matters, Polymeric Materials, and Biopolymers Our laboratory is focused on developments of statistical mechanics models to elucidate the thermodynamic properties and structure of polymeric materials and biopolymer systems. Our model studies have been extended to explore the role of the long-ranged electrostatic interaction on the self-assembly structure of like-charged macroions, the intramolecular self-assembly of a giant DNA, and the solution structure of polyelectrolytes. We are currently working on the structure of chromatin and nucleolus in the highly confined, crowded nucleus with applications to cancer cell diagnosis.

Dr. Chwen-Yang Shew

Yolanda A. Small Assistant Professor Department of Chemistry CUNY York College and The Graduate Center 94 - 20 Guy R. Brewer Blvd, Jamaica, NY 11451-0001 ysmall@york.cuny.edu www.york.cuny.edu/portal_college/small-yolanda-1

Publications Small, Y. A. “Bridging Thermodynamic and Kinetic Processes in Electrochemically Relevant Calculated Pourbaix Diagrams” J. Nat. Sci.., 2016, 3(2), 2334-2951. Small, Y. A.; et. al. “Proton Management as a Design Principle for Hydrogenase-Inspired Catalysts” Ener. and Env. Sci. 2011, 4, 3008-3020. Small, Y. A., et. al. “Photocatalytic Water Oxidation Process at the GaN (101bar0) – Water Interface” J. Phys. Chem. C, 2010, 114 (32),13695–13704.

Research Interests Keywords: Two main computational methods are applied to answer questions about the molecular interactions of catalysts and semiconductors: (1) Quantum Mechanical/Molecular Mechanical (QM/MM) modeling and simulations and (2) electronic structure methods using Gaussian-based Density Functional Theory (DFT).

Dr. Small’s research is at the i n t e r f a c e o f b i o l o g y, chemistry and condensed matter physics where she app l ies computa t iona l techniques to address questions ranging from reactions in enzymes to reactions at the aqueous/semiconductor interface.

2010- current Assistant Professor – York College CUNY 2007-2010 Postdoc – Brookhaven National Lab 2001-2007 Ph.D. – The Pennsylvania State University

Dr. Yolanda Small

Aaron Martin Socha Associate Professor of Chemistry Director of Center for Sustainable Energy Bronx Community College - CUNY Snow Hall 2155 University Ave Bronx, NY 10453 Email.aaron.socha@bcc.cuny.edu www.csebcc.org

Publications Socha  AM,  Simmons  B,  Singh  S.  Efficient  biomass  pretreatment  using  ionic  liquids  derived  from  lignin  and  hemicellulose.  Proceedings  of  the  Na:onal  Academy  of  Science  2014  111,  E3587  –E3595.   Sun  N,  Parthasarathi  R,  Socha  AM.  Understanding  Pretreatment  Efficacy  of  Four  Cholinium  and  Imidazolium  Ionic  Liquids  by  Chemistry  and  ComputaLon.    Green  Chemistry  2014,  16,  2546-­‐2557.     Socha  AM,  Plummer  S,  Simmons  B,  &  Singh  S.  Comparison  of  sugar  content  for  ionic  liquid  pretreated  Douglas-­‐fir  woodchips  and  forestry  residues.  Biotechnology  for  Biofuels.  2013,  6,  61.   Socha  AM,  Tan  YM,  LaPlant  KL,  Sello  JK.    Diversity-­‐oriented  synthesis  of  cyclic  acyldepsipepLdes  leads  to  the  discovery  of  a  potent  anLbacterial  agent.    Bioorg  Med  Chem.  2010,  18,  7193-­‐7202.   Socha  AM,  Sello  JK.  Efficient  conversion  of  triacylglycerols  and  faTy  acids  to  biodiesel  in  a  microwave  reactor  using  metal  triflate  catalysts.  Org  Biomol  Chem.  2010,  8,  4753-­‐4756.   Socha  AM,  Kagan  G,  Li  W,  Sello  JK,  Hopson  R,  Williard  P.    Diffusion  coefficient−formula  weight  correlaLon  analysis  via  diffusion-­‐ordered  nuclear  magneLc  resonance  spectroscopy  (DOSY  NMR)  to  examine  acylglycerol  mixtures  and  biodiesel  producLon.    Energy  and  Fuels,  2010,  24,  4518-­‐4521.  

Research Interests Keywords: Cellulosic Biofuels, Biodiesel, Renewable Ionic Liquids, Lignin, Biomass, Natural Products, Fermentation, Organic Synthesis and Spectroscopy.

Aaron is a natural product chemist with interests in r e n e w a b l e f u e l s a n d valorization of biomass. Current projects include lignin depolymerization and synthetic conversion to tetraalkylammonium ionic liquids. Other active areas of research include glycerol chemistry and structural a n a l y s i s o f n a t u r a l products.

2015- current Associate Professor of Chemistry - Bronx Community College 2015- current Director of Center for Sustainable Energy – CUNY 2012-current Research Affiliate - Lawrence Berkeley National Laboratory 2011-2014 Assistant Professor of Chemistry - Bronx Community College 2008-2011 Postdoctoral Fellow - Brown University (with Jason Sello) 2002-2008 PhD University of Rhode Island (with David Rowley) 1997-2001 BS Fordham University

Dr. Aaron M. Socha

Ruth E. Stark Distinguished Professor City College Dept. of Chemistry and Biochemistry CUNY Institute for Macromolecular Assemblies CCNY CDI 1S-11302, 85 St. Nicholas Terrace New York, NY 10031 Email.rstark@ccny.cuny.edu http://www.sci.ccny.cuny.edu/resgroup

Publications W. S. Lagakos, X. Guan, S.-Y. Ho, L. R. Sawicki, B. Corsico, K. Murota, R. E. Stark, J. Storch, Liver Fatty Acid-binding Protein Binds Monoacylglycerol in vitro and in Mouse Liver Cytosol, J. Biol. Chem., 2013, 288, 19805-15. T.H. Yeats, W. Huang, S. Chatterjee, H. M-F. Viart, M.H. Clausen, R. E. Stark, J.K.C. Rose, Biochemical characterization of CD1 and Putative Orthologs Reveals an Ancient Family of Cutin Synthase-like Proteins that are Conserved Among Land Plants, 2014, Plant J., 77, 667-675. O. Serra,* S. Chatterjee,* M. Figueras, M. Molinas, R.E. Stark, Deconstructing a plant m a c r o m o l e c u l a r a s s e m b l y : c h e m i c a l architecture, molecular flexibility, and mechanical performance of natural and engineered potato suberins, Biomacromolecules, 2014,15, 799-811. K. Dastmalchi, Q. Cai, K. Zhou, W. Huang, O. Serra, R.E. Stark, Completing the Jigsaw Puzzle of Wound-Healing Potato Cultivars: Metabolite Profiling and Antioxidant Activity, J. Agric. Food Chem., 2014, 62, 7963-7975. S. Chatterjee, R. Prados-Rosales, B. Itin, A. Casadevall, R.E. Stark, Solid-state NMR Reveals the Carbon-based Molecu lar Architecture of Melanized Cryptococcus neoformans Fungal Cells, J. Biol. Chem., 2015, 290, 13779-13790. Research Interests

Keywords: molecular biophysics, biopolymers, bioanalytical chemistry, solid- and solution-state NMR The Stark Laboratory uses structural biology approaches to study plant protective polymers, lipid metabolism, and potentially pathogenic melanized fungal cells. Study of the molecular and mesoscopic architectures underlying the integrity of cuticles in natural and engineered tomatoes and potatoes is undertaken using solid- and solution-state nuclear magnetic resonance (NMR), mass spectrometry, and atomic force microscopy. Ligand recognition and peroxisome proliferator-activated receptor interactions of fatty acid-binding proteins are under investigation by solution-state NMR and isothermal titration calorimetry. The molecular structure and development of melanin pigments within fungal cells are probed using (bio)chemical synthesis and solid-state NMR.

Dr. Stark’s biophysics research program focuses on the molecular structure a n d i n t e r - a c t i o n s o f p r o t e c t i v e p l a n t biopolymers, nutri-tionally important fatty acid-binding prote ins, and melanin pigments associated with human fungal infections.

2007 - current CUNY Dist. Prof., CCNY 1985 - 2007 Assoc.-Dist. Prof., Coll. of Staten Island 1979 - 1985 Asst. Prof., Amherst College 1977 - 1979 Postdoctoral Fellow, M.I.T. 1977 PhD, Physical Chemistry, UC San

Diego

Dr. Ruth E. Stark

Maria C. Tamargo Professor The City College of New York Department of Chemistry 160 Convent Avenue New York NY 10031 mtamargo@ccny.cuny.edu www.ccny-mbe.com

Publications J. DeJesus, G. Chen, L. C. Hernandez-Mainet, A. Shen, M. C. Tamargo, Strain compensated CdSe/ZnSe/ZnCdMgSe quantum wells as building blocks for near to mid-IR intersubband devices, Journal of Crystal Growth 425, 207 (2015) Z. Chen, T. A. Garcia, L. C. Hernandez-Mainet, L. Zhao, H. Deng, L. Krusin-Elbaum, and M. C. Tamargo, Molecular beam epitaxial growth and characterization of Bi2Se3/II-VI semiconductor heterostructures, Applied Physics Letters 105, 242105 (2014) A. P. Ravikumar, T. A. Garcia, J. De Jesus, M. C. Tamargo, and C. F. Gmachl, High detectivity short-wavelength II-VI quantum cascade detector, Applied Physics Letters 105, 061113 (2014) S. Dhomkar, U. Manna, L. Peng, R. Moug, I. C. Noyan, M. C. Tamargo and I. L. Kuskovsky, Feasibility of submonolayer ZnTe/ZnCdSe quantum dots as intermediate band solar cell material system, Solar Energy materials and Solar Cells, C 117, 604–609 (2013) Y. Yao, A. Alfaro-Martinez, K. J. Franz, W. O. Charles, A. Shen, M. C. Tamargo, and C. F. Gmachl, Room temperature and narrow intersubband electroluminescence from ZnCdSe/ZnCdMgSe quantum cascade laser structures, Applied Physics Letters 99, 041113 (2011)

Research Interests Keywords: Molecular Beam Epitaxy, compound semiconductors, II-VI semiconductors, photonic devices, nanomaterials, topological insulators. Materials growth, properties and applications of semiconductor multi-layered structures grown by molecular beam epitaxy (MBE). Areas of research activity include III-V compounds, strained-layer and short-period superlattices, surface and interface chemistry, visible light emitters, optoelectronic devices, wide bandgap II-VI compounds, II-VI/III-V heteroepitaxy, low dimensional nanostructures, selective area epitaxy, intersubband devices, quantum cascade lasers, VECSELs, topological insulators.

Maria C. Tamargo is Professor of Chemistry at the City College of New York. Her research is in semiconductor materials and nanostructures design, growth by epitaxial growth techniques, characterization methods, and applications.

1993 - present The City College of New York and

The Graduate Center - CUNY 1984-1992 Bellcore 1978-1984 AT&T Bell Labs 1972-1978 PhD (Johns Hopkins University) 1968-1972 BS (University of Puerto Rico)

Dr. Maria C. Tamargo

Ming Tang, PhD Assistant Professor Department of Chemistry 2800 Victory Blvd College of Staten Island Staten Island, NY 10314 Ming.tang@csi.cuny.edu http://www.csi.cuny.edu/faculty/departments/chemistry/TANG_MING.html

Publications "Advanced Solid-State NMR Approaches for Structure Determination of Membrane Proteins and Amyloid Fibrils", Tang M, Comellas G, Rienstra CM. Acc. Chem. Res., 2013, 46, 2080-2088. "Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer", Tang M, Nesbitt AE, Sperling LJ, Berthold DA, Schwieters CD, Gennis RB, Rienstra CM. J. Mol. Biol., 2013, 425, 1670-1682. "Solid-State NMR Study of the Charge-Transfer Complex between Ubiquinone-8 and Disulfide Bond Generating Membrane Protein DsbB" Tang M, Sperling LJ, Berthold DA, Nesbitt AE, Gennis RB, Rienstra CM. J. Am. Chem. Soc. 2011, 133, 4359-4366. "Structure and Mechanism of Beta-Hairpin Antimicrobial Peptides in Lipid Bilayers from Solid-State NMR Spectroscopy" Tang, M.; Hong, M. Mol. BioSyst. 2009, 5, 317-322. "Effects of Guanidinium-Phosphate Hydrogen Bonding on the Membrane-Bound Structure and Activity of an Arginine-Rich Membrane Peptide from Solid-State NMR", Tang, M.; Waring, A. J.; Lehrer, R. I.; Hong, M. Angew. Chem. Int. Ed. 2009, 47, 3202-3205. "Phosphate-Mediated Arginine Insertion into Lipid Membranes and Pore Formation by a Cationic Membrane Peptide from Solid-State NMR" Tang, M.; Waring, A. J.; Hong, M. J. Am. Chem. Soc. 2007, 129, 11438-11446. .

Research Interests Keywords: Membrane proteins, ion channels, amyloidogenic proteins, Phosphoinositide, solid-state NMR, protein aggregates, paramagnetic relaxation enhancement.

Ming Tang is an assistant professor in the chemistry and biochemistry programs at CUNY. His long-term research endeavor is to investigate the function-modulating interactions between p r o t e i n s a n d m e m b r a n e components by solving structures of membrane-associated protein complexes and aggregates. The elucidation of such structure-func t ion re la t ionsh ips w i l l contribute tremendously to our understanding of how proteins interact wi th l ip ids and/or cofactors to operate.

2013- current Assistant Prof. of Chemistry, College of Staten Island, CUNY

Dr. Ming Tang

Micha Tomkiewicz Professor Brooklyn College of CUNY Dept. of Physics, Brooklun College of CUNY, Brooklyn, NY 11210 Michatom@Brooklyn.cuny.edu http://academic.brooklyn.cuny.edu/physics/micha/

Publications

Research Interests Keywords: Climate Change, Physics of Sustainability, Energy. Environmental issues, science and society, photoelectrochemistry, electrochemistry, physics and chemistry of solid-liquid interfaces, morphology and transport properties of composite media, solar energy conversion and storage, photovoltaic devices, batteries . Strategy: Students will learn how to do energy audits and carbon footprints on a variety of scales. Students will do longitudal studies on the various components of the global efforts to change energy sources from reliance on fossil fuels to alternative energy sources.

2015- current Professor of physics and Chemistry, Brooklyn College, CUNY

1973 - 1976 IBM Thomas J. Watson 1971 – 1973 UC-Berkeley 1969 PhD - Hebrew University - Jerusalem

Dr. Micha Tomkiewicz Micha Tomkiewicz is a professor of physics and chemistry at Brooklyn College and the school for Graduate Studies of the City University of New York. He served as founding-director of the Environmental Studies Program and the Electrochemistry Institute at Brooklyn College; was divisional editor, Journal of the Electrochemical Society (1981-91); chairman, Energy and Technology Division, the Electrochemical Society (1991-93); and member, International Organizing Committee of the conferences on Photochemical Conversion and Storage of Solar Energy (1989-92).

Weekly blog on climate change at: http://climatechangefork.blog.brooklyn.edu/ Lori Scarlatos, Micha Tomkiewicz, Ryan Courtney; “Using an Agent-Based Modeling Simulation and Game to Teach Socio-Scientific Topics”, Interaction Design & Architecture Journal – IxD&A, N. 19, Winter 2013/2014, pp. 77 – 90. Yevgenie Ostrovskiy, Michael Cheng and Micha Tomkiewicz, “Intensive and Extensive Parametrization of Energy Use and Income in US States and in Global Urban Environments”, The International Journal of Climate Change: Impacts and Responses Volume 4, Issue 4, pp.95-107.(2013) Micha Tomkiewicz and Lori Scarlatos, “Bottom-up Mitigation of Global Climate Change”, the International Journal of Climate Change: Impacts and Responses Volume 4, Issue 1, pp.37-48 (2013) Micha Tomkiewicz; “Climate Change: The Fork at the End of Now”; Momentum Press (2011).  

Mariana Torrente Assistant Professor Department of Chemistry 2900 Bedford Avenue Ingersoll Hall Extension 343/345 Brooklyn NY mariana.torrente@brooklyn.cuny.edu

Publications A. Torrente, M.P., L.M. Castellano, and J. Shorter. Suramin inhibits Hsp104 ATPase and disaggregase activity. PLoS ONE. 9(10): e110115. (2014)

B. Torrente, M.P., and J. Shorter. The metazoan protein disaggregase and amyloid depolymerase system: Hsp110, Hsp70, Hsp40, and small heat shock proteins. Prion. 7(6): 457-463. (2013)

C. Torrente, M.P, Gelenberg, A.J., and Vrana, K.V. Boosting serotonin in the brain: is it time to revamp the treatment of depression? J Psychopharmacol. 26(5), 629-35. (2012)

D. Torrente, M.P., Zee, B.M.; Young, N.L.; Baliban, R.C; Leroy, G.; Floudas, C.A.; Hake, S.B.; Garcia B.A., Proteomic Interrogation of Human Chromatin. PLoS One, 6, (9), e24747. (2011)

E. Plazas-Mayorca, M.D. and Vrana, K.E. Proteomic investigation of epigenetics in neuropsychiatric disorders: A missing link between genetics and behavior? Journal of Proteome Research, 10 (1), 58?65. (2011)

Research Interests Keywords: We seek to understand the role of epigenetic mechanisms and protein folding in the etiology of neurodegenerative and neuropsychiatric disease. The central hypothesis of our research is that posttranslational modification (PTM) of histones and protein misfolding play a key role in linking genetic predisposition to cellular toxicity in neurodegenerative disease. Epigenetics and protein aggregation may reveal alternative mechanisms behind the occurrence of disease, serving as the missing link between genetic and environmental factors.

Dr. Torrente is interested in the m o l e c u l a r m e c h a n i s m s underlying neurodegenerative and psychiatric disease.

2015- current Assistant Professor, Brooklyn College; NIH Career Transition Award Fellow 2012-2015 IRACDA PENN-PORT Postdoctoral Fellow, University of Pennsylvania 2010-2012 NIH NRSA Postdoctoral Fellow, Penn State University College of Medicine 2010 Ph.D. in Chemistry, Princeton University

Dr. Mariana Torrente

Torrente,  M.P.,  L.M.  Castellano,  and  J.  Shorter.  Suramin  inhibits  Hsp104  ATPase  and  disaggregase  acLvity.  PLoS  ONE.  9(10):  e110115.  (2014).    Torrente,  M.P.,  and  J.  Shorter.  The  metazoan  protein  disaggregase  and  amyloid  depolymerase  system:  Hsp110,  Hsp70,  Hsp40,  and  small  heat  shock  proteins.  Prion.  7(6):  457-­‐463.  (2013).      Torrente,  M.P,  Gelenberg,  A.J.,  and  Vrana,  K.V.  BoosLng  serotonin  in  the  brain:  is  it  Lme  to  revamp  the  treatment  of  depression?  J  Psychopharmacol.  26(5),  629-­‐35.  (2012).    Plazas-­‐Mayorca,  M.D.  and  Vrana,  K.E.  Proteomic  invesLgaLon  of  epigeneLcs  in  neuropsychiatric  disorders:  A  missing  link  between  geneLcs  and  behavior?  Journal  of  Proteome  Research,  10  (1),  58?65.  (2011).  2011  

name Position Affiliation Address Address New York NY Email.email@cuny.edu www.cuny.edu/xxxx

Dr. Rein V Ulijn Rein Ulijn is founding director of the nanoscience initiative at the Advanced Science Research Centre at CUNY and Professor of Nanochemistry at Hunter College. His research is focused on minimalistic molecular materials and adaptive systems that are inspired by biology.

Dr Rein V Ulijn Director of Nanoscience Einstein Professor of Chemistry, Hunter College Advanced Science Research Centre St Nicolas Terrace New York NY Rein.Ulijn@asrc.ac.uk www.cuny.edu/asrc

Publications P.W.J.M. Frederix, G.G. Scott, Y.M. Abul-Haija, D. Kalafatovic, C.G. Pappas, N. Javid, N.T. Hunt, R.V. Ulijn and T. Tuttle, Exploring the Sequence Space for (Tri-)peptide Self-Assembly to Design and Discover New Hydrogels, Nature Chemistry, 2015, 7, 30-37. C.G. Pappas, T. Mutasa, P.W.J.M. Frederix, S. Fleming, S. Bai, S. Debnath, S. Kelly, A. Gachagan and R .V. U l i j n , Trans ien t Supramolecular Reconfiguration of Peptide Nanostructures using Ultrasound, Mater. Horiz., 2015, 2, 198-202. S. Debnath, S. Roy and R.V. Ulijn, Peptide Nanofibers with Dynamic Instability through Non-Equilibrium Biocatalytic Assembly, J. Am. Chem. Soc., 2013, 135, 16789-16792. A.R Hirst, S. Roy, M. Arora, A.K. Das, N. Hodson, P. Murray, N. Javid, J. Sefcik, J. Boekhoven, J.H. van Esch, S. Santabarbara, N.T. Hunt and R.V. Ulijn, Biocatalytic Induction of Supramolecular Order, Nature Chemistry, 2010, 2, 1089-1094. R.J. Williams, A.M. Smith, R. Collins, N. Hodson, A.K. Das, R.V. Ulijn, Enzyme Assisted Self-Assembly under Thermodynamic Control, Nature Nanotechnology, 2009, 4, 19-24. Research Interests

Keywords: molecular systems, bionanotechnology, hydrogels, peptides, biocatalysis, adaptive materials The Ulijn group are interested in the development of materials and systems that mimic biology’s adaptive properties but are much simpler. These materials (including gels, emulsions, structured surfaces and nanotubes) have potential applications in health care, cosmetics, lifestyle products, food science. These applications are sought in active collaboration with researchers and companies across the globe. The approach is cross-disciplinary and covers the entire range from fundamental understanding to eventual applications and societal benefit.

2014- current Director of Nanoscience, ASRC 2008-2014 Professor of Nanochemistry, University

of Strathclyde, Glasgow, UK 2003-2008 Associate Prof., U. of Manchester, UK 2001-2003 Postdoc. University of Edinburgh, UK 1998-2001 PhD University of Strathclyde, UK 1992-1998 MSc Wageningen University, NL.

Michele Vittadello Associate Professor of Chemistry and Env. Science Medgar Evers College of CUNY 1638 Bedford Avenue Brooklyn NY 11225 mvittadello@mec.cuny.edu www.gc.cuny.edu

Publications Bertasi,  F.  et  al.  Electrolytes  for  Secondary  Magnesium  BaNeries  Based  on  Chloroaluminate  Ionic  Liquids.  ChemSusChem,  2015,  8,  3096-­‐3076.      Negro,  E.  et  al.  The  influence  of  the  caTonic  form  and  degree  of  hydraTon  on  the  structure  of  NafionTM.  Solid  State  Ionics  2013,  252,  84-­‐92.    Harrold,  J.  W.  Jr  et  al.  FuncTonal  Interfacing  of  Rhodospirillum  rubrum  Chromatorphores  to  a  ConducTng  Support  for  Capture  and  Conversion  of  Solar  Energy.  J.  Phys.  Chem.  B  2013,  117,11249-­‐11259.        ViTadello,  M.  et  al.  Iodide-­‐ConducTng  Polymer  Electrolytes  based  on  Poly-­‐Ethylene  Glycol  and  MgI2:  Synthesis  and  Structural  CharacterizaTon.    Electrochimica  Acta  2011,  57,  112-­‐122.      Di  Noto,  V.  et  al.  Broadband  dielectric  and  conducTvity  spectroscopy  of  Li-­‐ion  conducTng  3D-­‐HION-­‐APEs  based  on  PEG400,  Zr  and  Al  Nodes.  Electrochimica  Acta  2011,  57,  192-­‐200.  

Research Interests Keywords: Energy Nanotechnology and Materials, Biohybrid Photosynthetic/Mitochondrial Systems, Polymer Electrolytes, Lithium/Magnesium Batteries, Supercapacitors, Fuel Cells, Photovoltaic Devices, Bionanotechnology, Environmental Elemental Analysis, Radioremediation. Investigation of fundamental physical-chemical properties of nanomaterials, materials and biomaterials with potential applications in the field of energy storage/generation and biotechnology; Design and assembly of new devices; High quality publications and patents.

Dr. Vittadello’s research is focused on the areas of nanotechnology and materials science, inorganic and physical chemistry

2015- current Associate Professor 2008-2015 Assistant Professor 2005-2008 Postdoc (Rutgers University) 2003-2005 Postdoc (Hunter College) 2000-2003 PhD (University of Padua)

Dr Michele Vittadello

Nan-Loh Yang Professor of Chemistry College of Staten Island 2800 Victory Boulevard Staten Island, NY 10341 nanloh.yang-cepm@csi.cuny.edu www.chem.csi.cuny.edu

Publications Ashish Punia, Edward He, Kevin Lee, Probal Banerjee, and Nan-Loh Yang, Cationic amphiphilic non-hemolytic polyacrylates with superior antibacterial activity. Chem. Commun., 2014, 50, 7071. Monica Apostol ;Tatsiana Mironava ;Nan-Loh Yang; Nadine Pernodet Miriam H Rafailovich. Cell sheet patterning using photo-cleavable polymers. Cell sheet patterning using photo-cleavable polymers. Polymer Journal . 2011; 43(8):723- Chong Cheng and Nan-Loh Yang” Well-Defined Diblock Macromonomer with a Norbornene Group at Block Junction: Anionic Living Linking Synthesis and Ring-Opening Metathesis Polymerization” Macromolecules, 2010, 43 (7), pp 3153–3155 Kai Su, Nurxat Nuraje, Lingzhi Zhang, I-Wei Chu, Hiroshi Matsui, and Nan-Loh Yang.“ First Preparations and Characterization of Conductive Polymer Crystalline Nanoneedles” Macromol. Symposia, Special Issue: Polymers at Frontiers of Science and Technology (2009), 279(1), 1-6. Su, Nurxat Nuraje, and Nan-Loh Yang*„An Open-Bench Method for the Preparation of BaTiO3, SrTiO3 and BaxSr1-xTiO3 nanocrystals at 80 oC”,ACS Langmuir,,(2007),23,11369-11371

Research Interests Keywords: Nanoeletronics, Superbugs killers, Photopolymers Novel Polyacetals, Supercapacitor Fast Switch, Amphiphilic Polyelectrolytes, Micelles Professor Yang’s research group is involved in developing amphiphilic non-hemolytic and antibacterial nanoparticle based structural tuningwith optimizing hydrophobic – hydrophilic molecular topography. The nanoelectronics research exploits the characteristic of micell reactors and interfacial polymerization.

Nan-Loh Yang is a Professor of Chemistry at College of Staten Island.. His research areas include: antimicrobial po lymer nanopar t ic le ; polymers with well-defined structure;and materials for nanoelectronics - giant dielectric constant element, fast cionductance switch, 4-stage memory and room temperature magnetoelectric coupling.

Current Professor of Chemistry, CUNY-CSI 1969-1970 Postdoc, Mount Sinai School of Medicine 1969 PhD Polymer Chemistry NYU-Poly

Dr. Nan –Loh Yang

Barbara Zajc Professor The City College of New York Department of Chemistry 160 Convent Avenue New York NY bzajc@ccny.cuny.edu http://www.ccny.cuny.edu/profiles/Barbara-Zajc.cfm

Publications Kumar, R.; Singh, G.; Todaro, L. J.; Yang, L.; Zajc, B.: E- or Z-Selective Synthesis of 4-Fluorovinyl-1,2,3-triazoles with Fluorinated Second-Generation Triazole-Substituted Julia-Kocienski Reagents, Org. Biomol. Chem. 2015, 13, 1536–1549 . Chowdhury, M.; Mandal, S. K.; Banerjee, S.; Zajc, B.: Synthesis of Regiospecifically Fluorinated Conjugated Dienamides, Molecules 2014, 19, 4418–4432 (Invited contribution for Molecules Special Issue on Fluorine Chemistry). Singh, G.; Kumar, R.; Swett, J.; Zajc, B.: Modular Synthesis of N-Vinyl Benzotriazoles, Org. Lett. 2013, 15, 4086-4089. Kumar, R.; Zajc, B.: Stereoselective Synthesis of Conjugated Fluoro Enynes, J. Org. Chem. 2012, 77, 8417-8427. Mandal, S. K.; Ghosh, A. K.; Kumar, R.; Zajc, B.: Expedient Synthesis of α-Substituted Fluoroethenes, Org. Biomol. Chem. 2012, 10, 3164-3167 (Featured on the Front Cover of the Journal, Issue 16).

Research Interests Keywords: Fluoroorganic chemistry, Biomolecules, Chemical Carcinogenesis

The research is focused in two main directions. One area involves development of methods for regiospecific introduction of fluorine into organic molecules. Here, an expanding toolbox of novel reagents for the synthesis of variously functionalized vinyl fluorides, highly versatile synthetic intermediates, is being developed. Another area of research involves the use of fluorine as probe in structure activity studies in the area of chemical carcinogenesis. Specifically fluorinated polycyclic aromatic hydrocarbons, their metabolites and their DNA conjugates are synthesized as probes to understanding cellular events after metabolism and DNA binding.

Zajc is an organic/b i o o r g a n i c c h e m i s t working in areas of (a) fluoroorganic chemistry, ( b ) c h e m i c a l carcinogenesis, and (c) synthetic methodology.

2013 Professor 2003 Associate Professor (CCNY) 2001 Assistant Professor (Substitute, CCNY) 1999 Associate Professor (Docent, U of Ljubljana) 1993 Assistant Professor (U of Ljubljana) 1991 Fogarty Fellow NIH (NIDDK) 1989 PhD

Dr. Barbara Zajc

Guoqi Zhang Assistant Professor Department of Sciences John Jay College of Criminal Justice 524 W 59th Street, 10019 New York NY Email: guzhang@jjay.cuny.edu http://www.jjay.cuny.edu/faculty/guoqi-zhang

Publications Z. Yin, G. Zhang, S. Zheng, T. Phoenix, J. C. Fettinger, “Assembling mono-, di- and tri-nuclear coordination complexes with a ditopic analogue of 2,2':6',2''-terpyridine: syntheses, structures and catalytic studies”, RSC Advances, 2015, 5, 36156-36166. G. Zhang, G. Proni, S. Zhao, Ed C. Constable, C. E. Housecroft, J. A. Zampese, M. Neuburger, “Chiral tetranuclear and dinuclear copper(II) complexes for TEMPO-mediated aerobic oxidation of alcohols: are four metal centres better than two?”, Dalton Trans. 2014, 43, 12313-12320 G. Zhang, K. V. Vasudevan, B. L. Scott, S. K. Hanson, “Understanding the mechanisms of c o b a l t - c a t a l y z e d h y d r o g e n a t i o n a n d dehydrogenation reactions”, J. Am. Chem. Soc. 2013, 135, 8668-8681. G. Zhang, S. K. Hanson, “Cobalt-catalyzed transfer hydrogenation of C=O and C=N bonds”, Chem. Commun. 2013, 49, 10151-10153. G. Zhang, B. L. Scott, S. K. Hanson, “Mild and homogeneous cobalt-catalyzed hydrogenation of C=C, C=O, and C=N bonds”, Angew. Chem. Int. Ed. 2012, 51, 12102-12106.

Research Interests Keywords: Inorganic/Organometallic Catalysis, Energy Conversion; Forensic Chemistry Description of research activities and strategy: Our research concerns over the design and synthesis of novel non-precious metal complexes and their applications in energy-related catalysis, supramolecular chemistry, anticancer drugs and forensic science.

Prof. Zhang is an inorganic chemist who has broad research in te res ts i n inorganic/organometalic chemistry, non-precious metal catalysis and forensic chemistry, with a focus on the synthesis of novel organic-inorganic functional materials.

2013- current Assistant Professor 2006-2013 Postdoc Los Alamos National Lab and

Uni. Basel 2001-2006 Ph.D., Institute of Chemistry, CAS

Dr. Guoqi Zhang

Shengping Zheng Assistant Professor Hunter College 695 Park Avenue New York, NY 10065 szh0007@hunter.cuny.edu http://www.hunter.cuny.edu/chemistry/faculty/Shengping/Shengping

Publications Yin, Z.; Zhang, J.; Wu, J.; Green, R.; Li, S.; Zheng, S. “Synthesis of o-Chlorophenols via an Unexpected Nucleophilic Chlorination of Quinone Monoketals Mediated by N, N’-Dimethylhydrazine Dihydrochloride” Org. Biomol. Chem. 2014, 12, 2854-2858. Yin, Z.; Zhang, J.; Wu, J.; Liu, C.; Sioson, K.; Devany, M.; Hu, C.; Zheng, S. “Double Hetero-Michael Addition of N-Substituted Hydroxylamines to Quinone Monoketals: Synthesis of Bridged Isoxazolidines” Org. Lett. 2013, 15, 3534-3537. Zhang, J.; Wu, J.; Yin, Z.; Zeng, H.; Khanna, K.; Hu, C.; Zheng, S. “An Expedient Stereoselective and Chemoselective Synthesis of Bicyclic Oxazolidinones from Quinols and Isocyanates” Org. Biomol. Chem. 2013, 11, 2939-2942. Zhang, J.; Yin, Z.; Leonard, P.; Wu, J.; Sioson, K.; Liu, C.; Lapo, R.; Zheng, S. “A Variation of Fischer Indolization Involving Condensation of Quinone Monoketals and Aliphatic Hydrazines” Angew. Chem. Int. Ed., 2013, 52, 1753-1757.  

Research Interests Keywords: Organic Synthesis, Anticancer, Antiviral, Heterocycles, Natural Products

1.  New methodologies in heterocycle synthesis

2.  Total synthesis of bioactive natural products

Our group focuses on the synthesis of b ioact ive heterocycles and their SAR studies.

2008- current Assistant Professor, Hunter College 2005-2008 Postdoc, Columbia University 2000-2005 PhD, Columbia University

Dr. Shengping Zheng

Shuiqin Zhou Professor of Chemistry College of Staten Island 2800 Victory Boulevard Staten Island, NY 10314 Shuiqin.zhou@csi.cuny.edu www.chem.csi.cuny.edu

Publications H. Wang, Y. Sun, J. Yi, J. Fu, J. Di, A. del C. Alonso, S. Zhou. Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy. Biomaterials, 2015, 53, 117-126. H. Wang, J. Yi, S. Mukherjee,‎ P. Banerjee, S. Zhou. Magnetic/NIR-thermally responsive hybrid nanogels for optical temperature sensing, tumor cell imaging and triggered drug release. Nanoscale, 2014, 6, 13001–13011. H. Wang, A. Mararenko, G. Cao, Z. Gai, K. Hong, P. Banerjee, S. Zhou, Multifunctional 1D magnetic and fluorescent nanoparticle chains for enhanced MRI, fluorescent cell imaging, and combined photothermal/chemotherapy, ACS Appl. Mater. Interfaces 2014, 6, 15309–15317. H. Wang, Z. Wei, H. Matsui, S. Zhou, One-pot synthesis of Fe3O4@Carbon quantum dots hybrid nanoflowers for highly active and recyclable visible-light driven photocatalyst. J. Mater. Chem. A, 2014, 2, 15740-15745. Y. Li, S. Zhou. Facile one-pot synthesis of organic dye-complexed microgels for optical detection of glucose at physiological pH. Chem. Commun. 2013, 49, 5553-5555. Research Interests

Keywords: responsive polymers, hybrid nanogels, nanoparticles, carbon dots, assembly, biosensing, drug delivery, cell imaging, environmental remediation The Zhou group is interested in the development of (1) glucose-responsive hybrid nanoparticles (NPs) for glucose sensing and self-regulated insulin delivery; (2) multifunctional nanomaterials from the combination of optically active NPs with responsive polymers for sensing, imaging, and therapy; and (3) composite nanomaterials from the complex assembly of carbon-based NPs, inorganic NPs, and other amphiphilies in the confinement of (bio)polymers and colloids for sensing, catalysis, and environmental remediation

Shuiqin Zhou is a Professor of Chemistry at CUNY College of Staten Island. Her research is focused on responsive polymer-nanoparticle (including carbon dots) hybrid nanogels, inorganic-carbon composite nanoparticles, and complex assembly of nanopart ic les for sensing, imaging, drug delivery, and environmental remediation.

2008- current Professor of Chemistry, CUNY-CSI 2002-2007 Associate Prof. of Chemistry, CUNY-CSI 2000-2002 Senior Chemist, Dow Chemical Company 1996-2000 Postdoc, SUNY at Stony Brook 1993-1996 PhD, Chinese University of Hong Kong 1988-1991 MSc, Xiamen University, China 1984-1988 BSc, Xiamen University, China

Dr. Shuiqin Zhou