BRENDA TutorialLigand Search

How to find ligands / metabolites such assubstrates, products, inhibitors etc.

Substances interacting with enzymes

Enter the ligand name ora part of it and performthe search

Choose „Ligands“ to display theenzyme-related information on vanillic acid

The result page shows all enzymesinteracting with the ligand, including

their derivatives, and their roles

you can displaythe molecularstructure

On the next page you getbasic information on theLigand Summary Page with…

…more detailed informationon the structure, synonyms, and their roles in theenzyme-ligand interaction, enzyme kinetic parameters, and references in BRENDA

you can directly switch to the„Substructure Search“ to find

similar ligands interacting withenzymes in BRENDA

On the result page all ligandsstructurally similar to the

searched ligand are displayed

If you find an appropriateligand, you can perform a search in BRENDA to getmore information

On the result page youfind further details ofthe searched ligand

Otherwise you could perform a new Substructure Search by

drawing the molceular structurewith the editor and choosingappropriate search options.