Both Dietary Protein and Fat Increase Postprandial Glucose Excursions in Children With Type 1...
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Both Dietary Protein and Fat Increase Postprandial Glucose Excursions in Children With Type 1 Diabetes, and the Effect Is Additive Featured Article: Carmel E.M. Smart, R.D., P.H.D., Megan Evans, R.D., PGRADDIPDIET, Susan M. O’Connell, M.D., F.R.A.C.P., Patrick McElduff, P.H.D., Prudence E. Lopez, M.D., Timothy W. Jones, M.D., F.R.A.C.P., Elizabeth A. Davis, M.D., P.H.D., Bruce R. King, M.D., P.H.D. Diabetes Care Volume 36: 3897-3 902 December, 2013
Both Dietary Protein and Fat Increase Postprandial Glucose Excursions in Children With Type 1 Diabetes, and the Effect Is Additive Featured Article: Carmel
Both Dietary Protein and Fat Increase Postprandial Glucose
Excursions in Children With Type 1 Diabetes, and the Effect Is
Additive Featured Article: Carmel E.M. Smart, R.D., P.H.D., Megan
Evans, R.D., PGRADDIPDIET, Susan M. OConnell, M.D., F.R.A.C.P.,
Patrick McElduff, P.H.D., Prudence E. Lopez, M.D., Timothy W.
Jones, M.D., F.R.A.C.P., Elizabeth A. Davis, M.D., P.H.D., Bruce R.
King, M.D., P.H.D. Diabetes Care Volume 36: 3897-3902 December,
2013
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STUDY OBJECTIVE To determine the effects of high-protein (HP)
and high-fat (HF) meals on postprandial glycemia in children using
intensive insulin therapy (IIT) Smart C. E.M. et al. Diabetes Care
2013;36:3897-3902
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STUDY DESIGN AND METHODS 33 subjects aged 817 years were given
four test breakfasts with the same carbohydrate amount but varying
protein and fat quantities: Low fat (LF)/low protein (LP) LF/HP
HF/LP HF/HP Smart C. E.M. et al. Diabetes Care
2013;36:3897-3902
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STUDY DESIGN AND METHODS LF and HF meals contained 4 and 35 g
fat, respectively LP and HP meals contained 5 and 40 g protein,
respectively An individually standardized insulin dose was given
for each meal Postprandial glycemia was assessed by 5-h continuous
glucose monitoring Smart C. E.M. et al. Diabetes Care
2013;36:3897-3902
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RESULTS Compared with the LF/LP meal, mean glucose excursions
were greater from 180 min after the LF/HP meal and from 210 min
after the HF/LP meal HF/HP meal resulted in higher glucose
excursions from 180 to 300 min Reduction in the risk of
hypoglycemia occurred after the HP meals Smart C. E.M. et al.
Diabetes Care 2013;36:3897-3902
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CONCLUSIONS Meals high in protein or fat increase glucose
excursions from 3 to 5 h postmeal Protein and fat have an additive
impact on the delayed postprandial glycemic rise Protein had a
protective effect on the development of hypoglycemia Smart C. E.M.
et al. Diabetes Care 2013;36:3897-3902