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BOOK REVIEWS Book Reviews Book Reviews Don’t Just Happen R eaders will be aware that every issue of Heart Lung and Circulation contains at least three book reviews. The books reviewed cover the same scope as the Journal itself, namely cardiology, cardiac surgery and basic science. Book reviews have been appearing in the Journal since 1995. The process is that publishers send their latest volumes to the Journal for review, the book review editor Robert Den- niss, assisted by the specialist editors select appropriate reviewers who are then requested to carry out the review within 2 months. The carrot is that the reviewer is allowed to keep the book. This may be from something as humble as a paper back, ranging through to a two volume, top of the range text book. The orchestrator of the whole process is the book reviews co-ordinator in the editorial office San- dra Hayes. She reminds and cajoles recalcitrant reviewers to return their reviews and then processes them for pub- lication. The editors would like to thank all those involved in the production of book reviews, especially Robert Denniss and Sandra Hayes, but also the reviewers themselves and the publishers who continue to send their valuable volumes for review. Franklin Rosenfeldt, Founding Editor Head Cardiac Surgical Research Laboratory The Alfred Hospital and Baker Institute Melbourne, Australia E-mail address: [email protected] doi:10.1016/j.hlc.2004.09.002 Coronary Pressure, Second Ed. Nico H.J. Pijls, Bernard De Bruyne, Kluwer Academic Publishers A ngioplasty and stenting for coronary artery disease has became a relatively mechanical process with a minimum of the scientific considerations which under- pinned its introduction. Early proceduralists used over- the-wire balloon catheters which allowed them to mea- sure translesional pressure gradients plus assessment of collateral flow by measurement of distal coronary pressure during balloon occlusion. Most modern interventionalists use monorail balloon catheters and do not perform routine coronary artery pressure measurements before and after intervention. A trial of therapy is often used in grey-zone cases. This well written book is authored by two enthu- siasts for a scientific and physiological approach to coro- nary artery disease and interventions. The title of the book aptly captures the focus of the technique but undersells its application to daily cardiology. Its conclusions apply to choosing vessels suitable for any invasive intervention, either coronary artery bypass grafting or percutaneous coronary interventions. The basic tool advocated by the authors is a coronary angioplasty guide wire capable of measuring pressure near its tip. The wire is thin enough not to partially occlude the distal vessel or stenosis and flexible enough to be safe to pass through coronary ar- teries or stenoses. Proximal pressures are measured by the guiding catheter. The key concept is that of myocar- dial fractional flow reserve. This is the maximum myocar- dial flow in the presence of a coronary artery stenosis as a fraction of the flow in the same vessel if there were no stenosis. It is important that this parameter is measured during maximal myocardial vasodilatation (maximum hy- peraemia) induced by intracoronary injection of papaver- ine or adenosine. All that is required is measurement of simultaneous coronary artery pressures in the proximal coronary artery or aorta and the distal coronary artery. Measurement of myocardial fractional flow reserve allows the functional significance of any type of epicardial arte- rial obstruction to be assessed and the long-term clinical outcome of removal or bypass of that obstruction to be pre- dicted. Additional measurement of distal coronary artery pressure during balloon occlusion of the artery provides information on the proportional contribution of collateral and direct coronary artery flows to perfusion of that vascu- lar bed. For instance, a myocardial fractional flow reserve of 0.50 indicates that the stenosis restricts maximum coro- nary flow in that bed to 50% of normal. Measurement of distal coronary pressure during balloon occlusion in this case might show 39% of maximal myocardial flow to be via the direct coronary artery and 11% by collaterals. After relief of the stenosis by stenting, the myocardial fractional flow reserve in this vascular bed might rise to 0.97 (i.e. 97% of maximum) and 96% of maximum flow might be derived from direct coronary flow and 1% by collaterals. The first few chapters are an excellent overview of coronary artery physiology and the various methods for assessing the severity and functional significance of a coronary stenosis. These sometimes abstract concepts are explained exceptionally well with simple clear diagrams and examples which reflect the authors’ long experience with teaching and research in this area. The equipment, techniques and pitfalls are outlined plus other chapters based on the authors’ published research that lead to the cut-off of 0.75 for a functionally significant myocardial © 2004 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier Inc. All rights reserved. 1443-9506/04/$30.00

Book Reviews Don’t Just Happen

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BOOKREVIEWS

Book Reviews

Book Reviews Don’t Just Happen

Readers will be aware that every issue ofHeart Lung andCirculation contains at least three book reviews. The

books reviewed cover the same scope as the Journal itself,namely cardiology, cardiac surgeryandbasic science.Bookreviewshavebeenappearing in the Journal since 1995. Theprocess is that publishers send their latest volumes to theJournal for review, the book review editor Robert Den-niss, assisted by the specialist editors select appropriatereviewers who are then requested to carry out the reviewwithin 2 months. The carrot is that the reviewer is allowedto keep the book. This may be from something as humbleas a paper back, ranging through to a two volume, top ofthe range text book. The orchestrator of the whole processidtl

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siasts for a scientific and physiological approach to coro-nary artery disease and interventions. The title of the bookaptly captures the focus of the technique but undersellsits application to daily cardiology. Its conclusions applyto choosing vessels suitable for any invasive intervention,either coronary artery bypass grafting or percutaneouscoronary interventions. The basic tool advocated by theauthors is a coronary angioplasty guide wire capable ofmeasuring pressure near its tip. The wire is thin enoughnot to partially occlude the distal vessel or stenosis andflexible enough to be safe to pass through coronary ar-teries or stenoses. Proximal pressures are measured bythe guiding catheter. The key concept is that of myocar-dial fractional flow reserve. This is the maximummyocar-dial flow in the presence of a coronary artery stenosis asa fraction of the flow in the same vessel if there were no

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s the book reviews co-ordinator in the editorial office San-ra Hayes. She reminds and cajoles recalcitrant reviewerso return their reviews and then processes them for pub-ication.The editors would like to thank all those involved in theroductionofbookreviews, especiallyRobertDennissandandra Hayes, but also the reviewers themselves and theublishers who continue to send their valuable volumesor review.

Franklin Rosenfeldt, Founding EditorHead Cardiac Surgical Research Laboratory

stenosis. It is important that this parameter is measuredduringmaximal myocardial vasodilatation (maximumhy-peraemia) induced by intracoronary injection of papaver-ine or adenosine. All that is required is measurement ofsimultaneous coronary artery pressures in the proximalcoronary artery or aorta and the distal coronary artery.Measurement ofmyocardial fractional flow reserve allowsthe functional significance of any type of epicardial arte-rial obstruction to be assessed and the long-term clinicaloutcomeof removal or bypass of that obstruction tobepre-dicted. Additional measurement of distal coronary artery

The Alfred Hospital and Baker InstituteMelbourne, Australia

pressure during balloon occlusion of the artery provides

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E-mail address: [email protected]

oi:10.1016/j.hlc.2004.09.002

oronary Pressure, Second Ed.ico H.J. Pijls, Bernard De Bruyne, Kluwer Academicublishers

ngioplasty and stenting for coronary artery diseasehas became a relatively mechanical process with a

inimum of the scientific considerations which under-inned its introduction. Early proceduralists used over-he-wire balloon catheters which allowed them to mea-ure translesional pressure gradients plus assessment ofollateral flowbymeasurementofdistal coronarypressureuring balloon occlusion. Most modern interventionalistssemonorail balloon catheters anddonotperformroutineoronary artery pressure measurements before and afterntervention. A trial of therapy is often used in grey-zoneases. This well written book is authored by two enthu-

2004 Australasian Society of Cardiac and Thoracic Surgeustralia and New Zealand. Published by Elsevier Inc. Al

information on the proportional contribution of collateralanddirect coronary artery flows to perfusion of that vascu-lar bed. For instance, a myocardial fractional flow reserveof 0.50 indicates that the stenosis restricts maximum coro-nary flow in that bed to 50% of normal. Measurement ofdistal coronary pressure during balloon occlusion in thiscase might show 39% of maximal myocardial flow to bevia the direct coronary artery and 11% by collaterals. Afterrelief of the stenosis by stenting, the myocardial fractionalflow reserve in this vascular bedmight rise to 0.97 (i.e. 97%ofmaximum) and 96% ofmaximumflowmight be derivedfrom direct coronary flow and 1% by collaterals.The first few chapters are an excellent overview of

coronary artery physiology and the various methods forassessing the severity and functional significance of acoronary stenosis. These sometimes abstract concepts areexplained exceptionally well with simple clear diagramsand examples which reflect the authors’ long experiencewith teaching and research in this area. The equipment,techniques and pitfalls are outlined plus other chaptersbased on the authors’ published research that lead to thecut-off of 0.75 for a functionally significant myocardial

and the Cardiac Society ofhts reserved.

1443-9506/04/$30.00