Upload
others
View
26
Download
1
Embed Size (px)
Citation preview
Copyright © 2016 CENTRION Science. All rights reserved.
CENTRION FERMENTATION SYSTEM
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
BIOTECHNOLOGY SCIENCE
www.centrion.co.kr
All about Centrion Fermentation and innovative research Cultivation solutions System.
CENTRION is product brand has played its honorable role of serving customer with wide
range of differently-customized equipments.
We to provide for our customers’ needs whether they are customized products, technical
support or other wise In light of quality maintenance through quality inspection for
all products we guarantee no one Will be better than us as we have competitive
edges on quick delivery system & reasonable price also offer.
CENTRION has its own professional research & development team of scientists and
product specialists that are supported by a sales team.
We focus on offering cultivation solution to the life sciences market and has worked
continuously to satisfy the strict facility standards required for Biotechnology.
Thank you.
01
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Company Overview
www.centrion.co.kr
• ISO9001
• ISO14001
02
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Certificate
www.centrion.co.kr 03
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Business Areas
www.centrion.co.kr 04
Machining Machining
Control Control
Rotor dynamic Rotor dynamic
• Motor control
• Sensor monitoring
• Control by Touch screen
• Magnetic Rotor
• Balacing
• Vibration
• Motor
• Process Simulation
• Bioprocess Stability
• GMP Line Design
• Down Stream
Fermentor Bioreactor Fermentor Bioreactor
• Laser Welding
• Pipe welding
• Lathe
• Milling
• Bending
• P&ID
• Vessel
• Mechanical Seal
• Agitator
Mechatronics Mechatronics
CENTRION Technology
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Technology
www.centrion.co.kr 05
• Fatigue analysis and evaluation of various experimental techniques Enclosures. • Thermal fluid dynamics simulation technology. • Precision 2D, 3D Modeling design, manufacturing processing technology. • Second high-speed rotating body, a pressure vessel mechanism design and development techniques.
Design Processing Analysis
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Technology
www.centrion.co.kr 06
Small culture
refine Concentrate recovered
Mass culture
Final Product
Lab-scale Bioreactor
Pilot or Plant Bioreactor
Centrifuge Ultra Filtration
Chromatography Column & devices
cGMP Facility
Establish
○ ○ ○ ○ ○
- Bioprocess Simulation
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Technology
www.centrion.co.kr 07
▪ Japanese B.E Marubishi Co.,Ltd exports products production. (By applying the ISO9001, ISO14001 quality
system and quality products manufactured in safe and clean production facilities).
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Producing Ability
www.centrion.co.kr 08
Japan's B.E Marubishi Co.,Ltd with a suitable fermentor with international standards and
quality standards in technology partnership
We continue to export to the completion of product development.
Cooperation Partners
www.centrion.co.kr 09
CUSTOMER CUSTOMER
Requets for solution Receiving problems CENTRION Cause analysis
CENTRION
1st solution)
2nd solution
1 CUSTOMER Request for problem solution by E-mail or telephone
2 CENTRION Receiving problems and firstly, to send temporary solution by on-line
3 CENTRION If first solution is not worked properly , centrion technical staff visit user’s site in order to repair
4 CUSTOMER To send corrective action report to prevent same problems
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION After Service Plan
www.centrion.co.kr 10
Introducing electronic measuring quality inspection system for improving quality of products and to minimize the failure rate conducting an inspection.
1 DO 0 to 200% of the concentration of DO outputs the measuring inspection
2 pH pH 0~14 of the concentration of pH outputs the measuring inspection
3 Temp Temperature of 0~150 ℃ outputs PT100 sensor measuring inspection
4 Analog Input
Output 4 ~ 20[mA], 0 ~ 1[V], 0 ~ 5[V], 0 ~ 10[V] The type sensor input output method selection measuring inspection
5 RS232C RS232C Communication port measuring inspection
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
CENTRION Quality Inspection System
Copyright © 2016 CENTRION Science. All rights reserved. www.centrion.co.kr
BIOTECHNOLOGY SCIENCE
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
BIOCANVAS LF BENCHTOP CONVENIENCE FERMENTATION SYSTEMS
In Touch With Life Science
11
All about CENTRION fermentation and cultivation innovative research solutions system.
1. Easy operation by finger, before experimentation of fermentation easy to calibrate pH, DO, temperature, foam
Sensors in use of User interface main control screen
2. Distinctive functions include various culture programming operations to control
3. Products designed for different culture experiment and applications, operation method touch screen controller
and the easy-way compact design takes up only a small space, even a small laboratory space can be used
efficiently.
4. CENTRION Fermentation system is able to connect to any PC for real-time recording and control within the vessel
and Intelligent self diagnostic system to maintain fermentation process.
5. Easy control of external device by fermentation controller
(O₂/CO₂analyzer, gasmixer, balancer, Level, external pump, analog printer)
6. Eight ways microprocessor controller system using parallel communication software data Logging, remote control,
including integrated control.
7. Agitation, Temp, pH, DO, ORP, O2, Antifoam, MFC, Feed Pump, GasMix and additional parameters such as analog
signals and can be controlled through a variety.
8. 4Gas signals available to send control signals to directly 4gas controller from main control system
9. Feed function is linked to the DO Cascade and the culture of a variety of conditions that can be applied to the
linked control program.
10. Data exporting interface USB port, One PC can monitor and manage all of data by network even each controller.
(1ch~6ch)
11. 1.5ml ~ 15L Total Vol. Vessel is available in a wide range.
12. Vessels can be easily disassembled and made the operation and the sensor and pump, analyzer, such as in /
output is easy.
13. Single Jacket / Double Jacket and can be used to select the drive motor.
Feature
www.centrion.co.kr 12
• Desingned for easy handling
• Culture experiments applications
• Simple Operation (Operation Made Simple)
• Complete Packages & User-friendly interface
• Exellent Value
Sensor
Basic TEMP pH DO Anti Foam ORP Optional OD O2 CO2 MFM or MFC Pressure Balancer
Display 7inch Wide Touch TFT LCD
Agitation Range 10 ~ 1500rpm
Motor drive AC Servo Motor, BLDC Motor AC Induction Motor
Time Range 100hours 59Minutes 59Seconds
Max. Noise Level <55dB(A)
Environment Ambient Temp 0~50℃, Humidity 85%RH
Power Requirements AC110~220V, 50/60Hz,Single Phase, 500W (FreeVoltage)
Fuse protection 10A
Weight 10Kg
Control System
Built-in SCADA System
* Built-in SCADA System - Voltage Specifications : 90~260V 50/60Hz Free Voltage - Built-in type SMPS Module UL certification. - CE product certification to enable component selection and PCB ARTWORK. - PWM frequency control AC Servo Motor, Ac induction Motor, BLDC Motor and Is, slow down as fast and smooth implementation. - RS232 x 2, RS422 or RS485 communication port, USB port, apply - Analog Input: 12 points, analog output: 12 points, analog record: 12 points - Temp. PH, DO Cascade,ORP,OD,O2,Co2,Agitation,MFC,Pressure Balancer Control
Feed Control Mode Fed-Batch Culture by DO, pH Interlock pump Control 4 x Built-in Feeding Pump(Boxer or Watson-Malow) External pump 2ea use
Communication port
Ethernet 1PC 1-6 connected to one controller (after completion of standard controller progress) Data logging, trend graph PC Contorl: process control (PID, the upper and lower values , programs, cascade, Feed)
Record Output Each sensor can be output by selecting data. D-SUB 25Pin Female Type, USB Excel file stored separately.
USB Measured data, setup data stored in the USB
Peristaltic pump
Pump 4built-in pumps, two external pump (optional)
Motor type AC Motor or DC Motor, minimum speed is 1rpm
Speed range 0~70rpm
Resolution 1rpm
Control mode Programmable PID Feeding control Pump can be assigned for Acid, Base, Antifoam, Feed
Bottom Heating Plate
Range Up to 90℃
Resolution 0.1℃
Power source 100-120V~50/60Hz or 210-230V~50/60Hz With electrical safety cutoff switch
Cat. NO. Description
FSBC-LF-L01 LAB Fermentor Controller
Ordering information
www.centrion.co.kr 13
Standard products
Vessel Total Volume (Liter) 1.5L 3L 5L 7L 10L 15L
Working Volume (Liter)
1 2.2 3 5 7 12
Material Borosilicate glass Autoclavable, SUS316L Stainless steel for Topplate and all fittings
Etc. Single & Double 1.5L~15L Total Vol. pH, DO, Foam,Level,Pressure Probe, Addtion Ports, Exhaust Port, Baffles 316L,Condenser
Aeration Flow rate 0~10LPM 0~20LPM
Option Air Flow Meter / Mass Flow Controller / Mass Flow Manual
Sparger Standard : Ring Sparger / Micro Sparger
Inlet Filter 0.2㎛ Disposable Hydrophobic Filter
Agitation Drive Direct Top Drive Servo Motor 200W~400W,BLDC Motor / Single Mechanical seal
Range 10~1500rpm
Impellers Rushton Standard With Fermentation / Pitched Blade Standard With Cell Culture Marine Blade or Spin Filter Note : Customized impellers are available
Temperature Thermostat system
0~150℃ ±0.1℃ / pt100Ω Probe Heating&Cooling PID Control / Built-in Heat Exchanger / Automatic Cooling Water Valve
pH Range / Resolution 0~14pH / 0.01pH
Probe Electrode Autoclavable, InPro 3030-MettlerToledo (temperature range - 0 ~ 140'C, the maximum pressure - 6bar)
Control mode Programmable PID Control system
DO Range / Resolution 0~200% or 0~20ppm / 0.1%
Probe Electrode Autoclavable Polarographic or Galvanic Oxygen Sensor -Mettler Toledo
Control mode
Programmable PID Control system DO Cascade to Agitation, Mas Flow, Feeding Pump Control - Oxygen enrichment module (optional) - Gas Mixing Station module (optional)
ORP
Range / Resolution Measuring range - 1000 ~ -1000 mv. / 1mV
Probe Electrode Autoclavable Redox potential, Oxidation of measurements-Mettler Toledo (Temperature range - 0 ~ 140'C, the maximum pressure - 2.5bar)
Anti Foam Range / Sensor Conductivity 0 ~ 300kΩ (Measuring the amount of foam)
OD (Optional) Range / Sensor Measuring range 0 ... 100 EBC 0 ... 100 EBC0 ... 400 FTU (Turbidity measurement)
MFM or MFC (Optional) Range / Sensor 0~10L/min (Air flow measurement) / Mass Flow Meter / Mass Flow Control
Level Sensor (Optional) Control Electrode type Hi/Low Level control
Balancer (Optional) Control 9,999.99g / RS232C Measured by the amount of weight on the scale output
Analog Input & output Control Various sensors are available by utilizing the analog input / output port
Analog Recording Control It can be the sensor output data value via the analog recording
www.centrion.co.kr 14
Specifications
• User-oriented access display interface functions
• Main screen / sub screen, enter the touch of a button can TREND
• Culturing the elapsed time value in accordance with a graph representation of the
respective sensor
• To select and display a graph in which the sensor can be selected
• The Trend graph screen makes it simple to track and export data on up to Twelve process
www.centrion.co.kr 15
If you need to update the controller Connect the USB to the front panel USB Port Update.
Main Control Screen (Graphical User Interface)
PC SCADA program can be remotely controlled in auto manual mode
www.centrion.co.kr 16
RS232 Port
LAN Port
Air Port in
Power in
Analog Port
Analog Recoder
AC out
USB/RS232C Port
7” Touch LCD
Servo Motor
Vessel
Agitator
Cold&Hot finger Power S/W
Feed Pump
Air Flow Meter
Temp,pH,DO, Foam,ORP Sensor Port
Configuration Layout
www.centrion.co.kr 17
Connect the LAN Cable can control the controllers 1CH~6CH.
PC Program
Internet Modem(LAN)
I-PAD Smart Phone
One PC can monitor and manage all of data by Wi-Fi network even each controller.
LAN
Note Book
Multi Controller Network System
Lighting LAB Photo Bioreactor
Light intensity control range
10 – 100%
Light module Selectable - Fluorescent lamp or LED
Light Color White, RED, Blue
Max. Lux Max. 10000lux
Control Mode On/off or set of the lighting Controller
Power Voltage 110V-220V, 50/60Hz, 10A
Specification Features Adjustable light intensity Fluorescent light source Expendable up to 3 lighting modules Scales-up Ideal for Pilot Custom Fabrication Easy operation and Long life
Cat. NO. Description
FSBC-LF-PB01 Photo Bioreactor Autoclavable Fermentor
3L – 15L
Ordering information
Lighting, the essential component for the photosynthesis reaction. We now offer special designed lighting module for your photosynthesis reaction. Light power and spectral composition,temperature and aeration gas composition can be set control. LED illumination with full spectrum imitated natural sunlight as closely as possible by emitting light peaks at 430nm and 630nm, without NDIR and ultraviolet spectrum components. Applied to microalgae, marine bio-industry, use a clean fuel production, Photosynthetic Microorganism culture.
White Red Blue
www.centrion.co.kr 18
Lighting Module Items
Single Vessel Cat. NO. Total Vol. (Working
Vol.)
Inner Dia. (mm)
D
Inner Height (mm)
H
Electrode Length (mm)
H:D
FSBC-LF01-01 1.5L(1L) Ø115 135 120 1.2:1
FSBC-LF01-02 3L(2.5L) Ø133 220 225 1.7:1
FSBC-LF01-03 5L(3L) Ø170 220 225 1.3:1
FSBC-LF01-04 7L(5L) Ø170 310 325 1.8:1
FSBC-LF01-05 10L(7L) Ø190 355 325 1.8:1
FSBC-LF01-06 15L(12L) Ø190 500 425 2.6:1
• Durable stainless steel supporting rods and bottom plate are designed. • Single glass type : Pyrex, Stainless316L. • Fast cooling/heating is achieved through the inner cooling coil and heating base unit.
Double Vessel Cat. NO. Total Vol. (Working
Vol.)
Inner Dia. (mm)
D
Inner Height (mm)
H
Electrode Length (mm)
H:D
FSBC-LF02-02 3L(2.5L) Ø130 220 225 1.7:1
FSBC-LF02-03 5L(3L) Ø145 300 225 1.3:1
FSBC-LF02-04 7L(5L) Ø160 330 325 1.8:1
FSBC-LF02-05 10L(7L) Ø190 355 325 1.8:1
FSBC-LF02-06 15L(12L) Ø190 500 425 2.6:1
• Double glass jacketed type vessel is spcially designed for temperature sensitive • Circulating water in double jacket for effective temperature control by large contact surface. • Connected to extra Water Bath for temperature control. • Provides sophisticated temperature control.
www.centrion.co.kr 19
Ordering Information
Single Round Vessel
Cat. NO. Total Vol. (Working
Vol.)
Inner Dia. (mm)
D
Inner Height (mm)
H
Electrode Length (mm)
H:D
FSBC-LF04-01 1.5L(1L) Ø115 135 120 1.2:1
FSBC-LF04-02 3L(2.5L) Ø133 220 225 1.7:1
FSBC-LF04-03 5L(3L) Ø170 220 225 1.3:1
FSBC-LF04-04 7L(5L) Ø170 310 325 1.8:1
FSBC-LF04-05 10L(7L) Ø190 355 325 1.8:1
• Vessle with an inner coil to achieve a fast cooling. • Single round vessel: round type under body. • Temperature control: Glass surrounding heating blanket. • Usually applied in animal cell fermentation.
PBR Vessel (Photo type)
Cat. NO. Total Vol. (Working
Vol.)
Inner Dia. (mm)
D
Inner Height (mm)
H
Electrode Length (mm)
H:D
FSBC-LF05-02 3L(2.5L) Ø133 220 225 1.7:1
FSBC-LF05-03 5L(3L) Ø170 220 225 1.3:1
FSBC-LF05-04 7L(5L) Ø170 310 325 1.8:1
FSBC-LF05-05 10L(7L) Ø190 355 325 1.8:1
FSBC-LF05-06 15L(10L) Ø190 355 325 1.8:1
• Single vessel type, LED Bar inside to make growth by exposing light into algae • Illumination : 430nm, 680nm, White,Red,Blue LED • LED inside / flourscent jacket
Bowl Vessel Cat. NO. Total Vol. (Working
Vol.)
Inner Dia. (mm)
D
Inner Height (mm)
H
Electrode Length (mm)
H:D
FSBC-LF03-04 7L(5L) Ø160 330 325 1.8:1
FSBC-LF03-05 10L(7L) Ø190 355 325 1.8:1
FSBC-LF03-06 15L(12L) Ø190 500 425 2.6:1
• Stainless Double Jacket in upper body, Single Glass in under body • Circulating water in double jacket for effective temperature control by large contact surface • Connected to extra Water Bath for temperature
www.centrion.co.kr 20
Ordering Information
Part Name Cat. NO. Description
Pitched Paddle Impeller
FSBC-LF-IM03-01 Pitched Paddle Impeller Ø65, 3Liter Vessel, 2ea/pk
FSBC-LF-IM03-02 Pitched Paddle Impeller Ø85, 5~7Liter Vessel, 2ea/pk
FSBC-LF-IM03-03 Pitched Paddle Impeller Ø100 10~15Liter Vessel, 2ea/pk
• More efficient than flat blade impeller • Flow is discharged both axially and radially depending on the angle
Part Name Cat. NO. Description
Rushton 6-Blade Impeller
FSBC-LF-IM01-01 Rushton 6-Blade Impeller Ø50, 1.5L iter Vessel, 3ea/pk
FSBC-LF-IM01-02 Rushton 6-Blade Impeller Ø60, 3L iter Vessel, 3ea/pk
FSBC-LF-IM01-03 Rushton 6-Blade Impeller Ø72, 5~7L iter Vessel, 3ea/pk
FSBC-LF-IM01-04 Rushton 6-Blade Impeller Ø80 10~15L iter Vessel, 3ea/pk
• Rushton turbine impeller is located from middle to bottom and basically used to agitate liquid in vessel. • It makes the flow to the same direction with turning radius and has features of paddle and propeller types to be available for high-speed rotation by minimizing resistance. • General model to be used due to the highest ventilation efficiency • Available for the agitator assemblies, both lipseal.
Part Name Cat. NO. Description
Pitched Blade Impeller
FSBC-LF-IM02-01 Pitched Blade Impeller Ø60, 3Liter Vessel, 2ea/pk
FSBC-LF-IM02-02 Pitched Blade Impeller Ø72, 5~7Liter Vessel, 2ea/pk
FSBC-LF-IM02-03 Pitched Blade Impeller Ø80 10~15Liter Vessel, 2ea/pk
• More efficient than flat blade impeller • Flow is discharged both axially and radially depending on the angle
www.centrion.co.kr 21
Ordering Information
Part Name Cat. NO. Description
Marine Impeller
FSBC-LF-IM04-01 Marine Impeller Ø60, 3Liter Vessel, 1ea/pk
FSBC-LF-IM04-02 Marine Impeller Ø80, 5~7Liter Vessel, 1ea/pk
FSBC-LF-IM04-03 Marine Impeller Ø100 10~15Liter Vessel, 1ea/pk
• Applied to damageable cell • It stirs liquid from down to up rotating in low-speed since it has the large surface of wings
Part Name Cat. NO. Description
Foam Breaker FSBC-LF-IM06-01 Foam Breaker 70, 3Liter Vessel, 1ea/pk
FSBC-LF-IM06-02 Foam Breaker 90, 5~7Liter Vessel, 1ea/pk
FSBC-LF-IM06-03 Foam Breaker 110 10~15Liter Vessel, 1ea/pk
• Our customized foam breaker helps you to maintain the proper foam level. • Installed in upper side of inside shaft, used in bursting fermentation foam. • It is not used in the case of animal cell fermentation since there is barely any foam.
Part Name Cat. NO. Description
Hollowed Paddle Impeller
FSBC-LF-IM05-01 Hollowed Paddle Impeller Ø60, 3Liter Vessel, 1ea/pk
FSBC-LF-IM05-02 Hollowed Paddle Marine Impeller Ø80, 5~7Liter Vessel, 1ea/pk
FSBC-LF-IM05-03 Hollowed Paddle Marine Impeller Ø100 10~15Liter Vessel, 1ea/pk
• It stirs liquid from up to down rotating in low-speed since it has the large surface of wings. • Extra additional it
www.centrion.co.kr 22
Ordering Information
Copyright © 2016 Centrion Science. All rights reserved. www.centrion.co.kr
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
BIOTECHNOLOGY SCIENCE
INNOVATIVE BIOTECHNOLOGY SCIENCE COMPANY
BIOCANVAS SF IN-SITU STERILIZABLE FERMENTATION SYSTEMS
In Touch With Life Science
23
Pilot SIP(Sterilization-in-place) Fermentor
The CENTRION brand offers pilot and profuction scale bioreactor/fermentation systems for all of your large scale fermentation needs. BIOCANVAS SF Fermentor designs order-made equipment that is designed to best fit the culture conditions, culturing the object you want. stainless steel vessel and in situ Automatic sterilization System and how to use a separate sterile devices do not need to be used, in large fermentation scale-up is possible equipment. BIOCANVAS SF of sterile fermentation system (in situ automatic sterilization system) is designed to be easy to use as a lab scale fermentor. Heater has been installed on the jacket of the vessel can raise the temperature to a level to sterilize the vessel, as well as temperature control of the vessel does not require a separate sterilization system. Culturing cells and microbes could not be any easier with our full automation control of sterilization and fermentation process. BIOCANVAS SF Fermentor can be used to develop new products in the company's laboratory or university.
Features • Intelligent 17" wide touch screen Industrial PC fermentation controller • PLC Controller is applied for minimizing size and making simple set-up process • CPU and sensor board into One-board solve problems immediately • High density fermentation : DO-stat, pH-stat, Exponential feeding, etc • DO Cascade function and automation control • Remote control by PC software Data Logging system • Automatic head lift system built-in to move Top plate easily • Everything on one skid frame : Easy to install and move additional vessels and vessel controllers • Accurate temperature control with cooler and heater • Automatic flow control: mass flow controller • All-in-one system including seed fermentor and main fermentor • Applied stainless pipe transfer line for perfect sterilization and user’s convenience • Top Plate approach adopted in the European Design • The level of cGMP IQ / OQ compliance
Head Lifting System • Head plate is lifted by air cylinder and guided by the two sets of linear motion guide • Safety pin is used to hold the lifted head plate • Lifting system is made of stainless steel(SUS 304) that it is rustles • Basic system with the 50L-500L capacity
www.centrion.co.kr 24
Pilot Production Scale Fermentation System
Pilot Fermentor
Vessel volume
Total Capacity(L) 30L 50L 70L 100L 150L 300L 500L 1000L
Working Volume(L) 21L 35L 50L 70L 100L 210L 350L 700L
Agitation
Drive & Range 30L ~500L : AC motor Top drive(mechanical seal driving) 50~1,000 ±1 RPM(In the condition of no load)
Control Manual or automatic control of agitation speed
Impellers Rushton turbine impeller, Foam breaker(SUS 316L)
Sensor & Control Magnetic hall sensor, PID control
Agitation Type Top Drive(Mechanical Seal) or Bottom Drive(Magnetic Coupling)
Head Lift The head lift system is powered by air cylinder and guided by two sets of linear motion guide
Materials & Finish Vessel/Piping SUS 316L, SUS 304(electrolytic polishing)
Sterilization Heat exchanger or inject steam into jacket.(105℃~130℃)
Aeration Sparger Ring sparger(SUS 316L)
Filter Inlet(0.2㎛), Outlet filter(0.2㎛)
pH Range / Electrode 2.0~12.0 pH of set point, PID control / Gel Type
DO Range / Electrode 0~200% or 0~20ppm, PID control / Polarographic Type
Temperature Range & Sensor Ambient + 3℃~80℃ (0.1℃), RTD(Pt-100), PID control
Pressure Control The back pressure is controlled manually and/or automatically
Control Panel 17” Touch Screen Color LCD
Control program Process, Trend, Calibration Mode control display. all the programmed setting values will be automatically stored into the built-in memory.
Processor PLC system
Setting Automated sterilization process Automated fermentation program Valve control
Communications Memory stick, printer, computer, etc with the RS-232C communication protocol
Data Storage pH, DO, Pressure, Temperature and Agitation speed
• According to customer requirements and the intended use by changing some standards it can be produced. • The control software also can be produced according to customer requirements.
Pilot scale bioreactor standard specifications
www.centrion.co.kr 25
Pilot Production Scale Fermentation System
In-situ Sterilizable Fermentor BIOCANVAS SF Series
• According to customer requirements and the intended use by changing some standards it can be produced. • The control software also can be produced according to customer requirements.
Pilot scale bioreactor standard specifications
• Vessel Ratio (H/D) - 2:1 - Total Vol. L / Working Vol. L • Vessel Pressure Certification Stamp - No Stamp / ASME Stamp • Vessel Surface finish - Inside / outside : 0.8㎛ / 1.2㎛ • Sight glass 1 ea : Oblong type
• Top Plate - Exhaust/Port/Pressure Gauge with diaphragm /Pressure Transmitter/Foam Sensor/Septum Port 4ea/ Inoculum Port • Upper Port - Aeration/Aeration by pass/Circle Light/ Rupture Disk
• Lower Port - Sampling / pH / DO / Temp / Etc. • Harvest
www.centrion.co.kr 26
Pilot Production Scale Fermentation System
Inner Vessel design pressure : -1~ 4 bar(g)
Inner Vessel working pressure : 2 bar(g)
Inner Vessel Material: SUS 316 L
Inner Vessel Design temp : 150˚C
Inner Vessel Working temp : 10 ~ 65˚C
Inner Vessel SIP temp : 121˚C
Jacket design pressure : Max. 6 bar(g)
Jacket working pressure : Max. 4bar(g)
Jacket Material : SUS 304
Vessel Temp, Pressure
BIOCANVAS SF Series (30L~1000L)
Main Controller
Peristaltic Pump
Agitator
Sampling Port
Aeration Air Filter Housing
Heat. Exchanger
Vessel
Frame
Harvest
Reagent Bottle
Sensor Port
Sight Glass
Cat. NO. Description
FSBC-SF-S01 In-situ Sterilizable Fermentor 30L
FSBC-SF-S02 In-situ Sterilizable Fermentor 50L
FSBC-SF-S03 In-situ Sterilizable Fermentor 70L
FSBC-SF-S04 In-situ Sterilizable Fermentor 100L
Ordering information
Cat. NO. Description
FSBC-SF-S05 In-situ Sterilizable Fermentor 150L
FSBC-SF-S06 In-situ Sterilizable Fermentor 300L
FSBC-SF-S07 In-situ Sterilizable Fermentor 500L
FSBC-SF-S08 In-situ Sterilizable Fermentor 1000L
www.centrion.co.kr 27
Head Lift
Control Valve
• According to customer requirements and the intended use by changing some standards it can be produced. • The control software also can be produced according to customer requirements.
Pilot Production Scale Fermentation System
• The control software also can be produced according to customer requirements.
Pilot scale bioreactor standard specifications
www.centrion.co.kr 28
Main Control System Specification
* LG PLC CONTROLLER. ▪ Control Cabinet : Body case with touch screen display ▪ 17” Resistive touch color LCD panel for, data input and display/Touch Screen Industrial PC unit ▪ On/Off diaphragm valves with air solenoid valves ▪ Automation program & software ▪ Functions: pH, DO, Foam, Temperature, Agitation, Peristaltic pump control,Calibration & Recalibration, Etc. ▪ Real time data as a graphs for rpm, temp, DO, pH, and foam ▪ Existing data will be graphed with its own real-time system ▪ Displays and saves date, time, rpm, temperature, DO, pH, and foam ▪ Data logging software for PC: Spread sheet format & Graph type of parameters ▪ View Excel: Accumulated data in Excel format ▪ Fed Batch - pH stat, DO stat, user feeding profile, and exponential feeding On/Off & Auto Mode setting ▪ Automatic DO control - Feed pump ▪ Alarm Function - All measured and control parameters: alarm low/high limits - Screen display ▪ Automatic/Manual sterilization system ▪ Operation mode: Stop/Sterilization/ Cooling/Culture ▪ Set cooling temp ▪ User setting and programmable / Security: password protected ▪ SCADA functionality can be added(optional) (Remote monitoring the system operation via internet)
Pilot Production Scale Fermentation System
In-situ Sterilizable Fermentor BIOCANVAS SF Series
SCADA SYSTEM
www.centrion.co.kr 29
* Introduction to SCADA SYSTEM Focus on remote monitoring and control system or SCADA monitoring and control system, also known as a data acquisition system for monitoring and control functions says. SCADA systems are analog or digital signals on the communication path to the remote device, the status information data to the remote small device (remote terminalunit) to collect, receive, record and display on the remote device to the central control system which monitors control. * SCADA SYSTEM control practices They are connected by a relay module local controllers PC 1 as Each local controller to the remote control. The local controller of P / V, S / V, Valve ON / OFF, Control State collects data in real time. The data collected is DB (Data Base) is stored in Graph, the report output. - The central control room at System Run / Stop, Valve On / Off, S / V, Control Command and set the remote control. User Login grading to enhance the security features. This is connected to the separate program SCADA communication protocol matched DLL files are also provided.
Pilot Production Scale Fermentation System
Lighting Pilot Photo Bioreactor
Light intensity control range
10 – 100%
Light module Fluorescent LED Lamp
Light Color White, RED, Blue
Max. Lux Max. 10000lux
Control Mode On/off or set of the lighting Controller
Power Voltage 110V-220V, 50/60Hz, 15A
Specification Features
Adjustable light intensity Fluorescent light source Expendable up to 3 lighting modules Scales-up Ideal for Pilot Custom
Fabrication Easy operation and Long life
Cat. NO. Description
FSBC-PP-PB01 Photo Bioreactor Autoclavable Fermentor
30L – 200L
Ordering information
PBR (Photobioreactor: photobioreactor) is The particular microorganisms that require light from microorganisms and microorganisms such as that just Chlorella growing in the sea water of the proper amount of light, temperature and carbon dioxide because the photosynthetic this microorganism as plant haejumyeon supply are self-culture well and so may reduce the carbon dioxide for photosynthesis by giving the current supplied to the carbon dioxide in accelerating the global warming on the photobioreactor effectively the advantage of producing a material by culturing a nutrient and via Chlorella. Photobioreactor will be a gas which is supplied carbon dioxide to the fermentor, unlike normal culturing marine microalgae of different culture conditions than are many different Chlorella production design the device in the structures of each micro algae culture well. Is attached to the vessel with a source of light, LED light, and light intensity depending on the culture conditions and the culture medium to adjust the lighting time, and so on. It is possible to precisely measure the growth of biomass, cleaning materials and health food, cosmetics (chlorella) and is used to cultivate a lot. - LED illumination with Full spectrum imitates natural sunlight as closely as possible by emitting light peaks at 430nm and 630nm, without NDIR and ultraviolet spectrum - Remote` control by PC software Data Logging system components
www.centrion.co.kr 30
Lighting Module Items
Temp. Range & sensor Ambient 3℃~80℃, RTD(Pt-100), PID control
Sparger & Gas mode Micro sparger, 2 gas and 4 gas mixer(option)
Inlet Filter 0.2㎛ air filter cartridge
Filter & Condenser 0.2㎛ air filter cartridge, SUS 316
pH Range 0~14.0 pH of set point, PID control
pH Electrode Gel Type
DO Range 0~20ppm or 0~100%, PID control
Heating System Cartidge heater
Light sourse Device Selectable - Fluorescent lamp or LED
LED Lighting Intensity adjustable from 0 to 100 %, Maximum light intensity1000 µmol(photon)/m2/s
Light Regime Static or dynamic (sinus, daylight, pulse form)
Peristaltic pump Control 4 constant speed pumps each assignable to a wide variety of function for control of acid, base, foam and feed
Recording pH, DO, Temp., Foam, etc.
Pilot PBR Fluorescent LED lamp Case
www.centrion.co.kr 31
Lighting Pilot Photo Bioreactor
Lighting Module Items
HEAD OFFICE
Bucheon Techno Park Ssangyong 3cha 397, Seokcheon-ro, Ojeong-gu, Bucheon-si, Gyeonggi-do, Rep, of KOREA
Tel : +82_32_624_2060
Fax : +82_32_624_2059
www.centrion.co.kr / Email : [email protected]
Copyright © 2016 Centrion Science. All rights reserved. V2.0
BIOCANVAS Customers want and diverse culture will be drawn correctly.