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It could be argued that, in the long term, cartels inevitably fall victim to competition from low-cost producers which decline to join them. The current example of a low-cost producer is of course China which is exploiting low-wage Chinese workers and doing minimal innovation (but see the abstract from Sinopec below). How does all this relate to catalysts? Most industrial chemicals are made by catalytic processes developed by multi-disciplinary teams in industrial R&D laboratories. But innovation in industrial chemistry has almost ceased in the West because so many R&D laboratories have been closed. There have been three reasons for these closures: short- termism of shareholders, competition from China, and legal action against cartels. The relative contributions which these three pressures make to the current malaise of the chemical industry are hard to quantify. The first two are intractable, but the third could be resolved. If the legal pressures on cartels were to be relaxed, by repeal of national and international anti-trust legislation, innovation could start again and ultimately we would all be the richer. I am grateful to Dr Chris Drew (SORIS) and Mr Derek Heathcote (formerly of Laporte Fluorides) for constructive suggestions and additions to this Editorial. Alan E. Comyns * The Daily Telegraph (London), 11 May 2005, 31 MARKETS AND BUSINESS Metallocenes to rise According to a report by the Freedonia group, the demand for metallocene and single site polymers is expected to rise by 20%/y to reach 2.31 M tonne/y in 2009. The demand will be driven by the performance and processing advantages of these materials, although more rapid growth will be limited by the high costs of the catalysts. LLDPE will continue to be the polymer most in demand, with demand growing by 17%/y from 612,000 tonne/y in 2004 to 1.34 M tonne/y in 2009. US demand for metallocene grades of polypropylene are expected to rise by 30%/y from 70,000 tonne/y in 2004 to 261,000 tonne/y in 2009. Plastics and Rubber Weekly, 15 Apr 2005, 16 Spanish HDS projects The majority of projects currently underway in the refining sector are for hydrodesulfurization (HDS) units that produce fuel with very low sulfur levels. These fuels meet new EU environmental standards that are listed in a table. HDS processes basically comprise mixing streams of fuel and hydrogen in the presence of a catalyst that enables fuel desulfurization to occur. A table contains a list of companies that licence HDS technology. They include ABB Lummus, Axens, ExxonMobil, Haldor Topsoe, Howe-Baker, Linde, and UOP. Cepsa is currently investing 169 M in HDS units for its refineries in Algeciras, Huelva, and Tenerife. Technology is being licensed from Axens, UOP, and Haldor Topsoe. Repsol is investing 260 M in HDS projects at its Bilbao and Petronor refineries. A table contains information about HDS projects in South America involving the participation of Spanish companies. Ingenieria Quimica, Dec 2004, (419), 75-77 (in Spanish) Sinopec 2004: production and operation: R&D In 2004, Sinopec proactively developed core technology and proprietary technology for its principal operations and achieved fruitful results with 639 domestic patents and 48 foreign patents being granted. Breakthrough was achieved in exploration in marine phase sedimentary structure in southern China. Additionally, the company successfully developed technologies to improve the recovery rate in oilfields having complex faultage, flexible and diversified FCC technology (FDFCC), sulfur removal and olefin content reduction technology through selective hydrofining of catalytic gasoline (RIDOS), and 150,000 tonne/y three- reactor PET technology. Progress was made in the construction of information systems. ERP system was deployed at 23 entities and its integrated advantage became more prominent. The comprehensive oilfield management system and the Ningbo- Shanghai-Nanjing crude oil pipeline transportation and distribution management system were completed and put into operation. Sinopec Profits for FY 2004, 29 Mar 2005, 12 (Sinopec Corp, Beijing, China, Website: http://www.sinopec.com.cn) Biotechnology community watch: collaborations and acquisitions During Jan-Feb 2005, fourteen collaborations and four acquisitions involving North Carolina biotechnology companies were announced. BT Catalyst, Mar-Apr 2005, 19 (2), 4 (Website: http://www.ncbiotech.org/ncindustry/news/btcat/btcat. cfm) COMPANY NEWS Albemarle announces record 1Q 2005 results Albemarle Corp reported 1Q 2005 net income, excluding special items, of $25.2 M, which was 53% higher than 1Q 2004, due to strong performance in each of the company’s three business segments. The company reported record net sales of $510 M for 1Q 2005, up $188 M compared to 1Q 2004, due in large part to the Jul 2004 acquisition of the Akzo Nobel refinery catalysts business. Catalysts segment net sales were $172.8 M, up $149.9 M versus 1Q 2004, due mainly to the addition of the refinery catalyst business and strong sales of hydroprocessing catalysts. R&D expenses were $10.98 M for 1Q 2005 ($4.579 M in 1Q 2004). Albemarle 1Q 2005 results, 26 Apr 2005 (Albemarle Corp, 330, South Fourth Street, PO Box 1335, Richmond, VA 23210, USA. Tel: +1 804 788 6000. Fax: +1 804 388 7686. Website: http://www.albemarle.com) Basell raises the bar for gas-phase PE catalysts Basell Polyolefins has introduced Avant Z 230, a new generation of Ziegler titanium catalysts for use in 2 JUNE 2005 FOCUS ON CATALYSTS

Biotechnology community watch: collaborations and acquisitions

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Page 1: Biotechnology community watch: collaborations and acquisitions

It could be argued that, in the longterm, cartels inevitably fall victim tocompetition from low-cost producerswhich decline to join them. Thecurrent example of a low-costproducer is of course China which isexploiting low-wage Chinese workersand doing minimal innovation (but seethe abstract from Sinopec below).

How does all this relate tocatalysts? Most industrial chemicalsare made by catalytic processesdeveloped by multi-disciplinary teamsin industrial R&D laboratories. Butinnovation in industrial chemistry hasalmost ceased in the West becauseso many R&D laboratories have beenclosed. There have been threereasons for these closures: short-termism of shareholders, competitionfrom China, and legal action againstcartels. The relative contributionswhich these three pressures make tothe current malaise of the chemicalindustry are hard to quantify. The firsttwo are intractable, but the third couldbe resolved. If the legal pressures oncartels were to be relaxed, by repealof national and international anti-trustlegislation, innovation could startagain and ultimately we would all bethe richer.

I am grateful to Dr Chris Drew(SORIS) and Mr Derek Heathcote(formerly of Laporte Fluorides) forconstructive suggestions andadditions to this Editorial.

Alan E. Comyns

* The Daily Telegraph (London), 11 May 2005, 31

MARKETS ANDBUSINESS

Metallocenes to rise

According to a report by theFreedonia group, the demand formetallocene and single site polymersis expected to rise by 20%/y to reach2.31 M tonne/y in 2009. The demandwill be driven by the performance andprocessing advantages of thesematerials, although more rapid growthwill be limited by the high costs of thecatalysts. LLDPE will continue to bethe polymer most in demand, withdemand growing by 17%/y from612,000 tonne/y in 2004 to 1.34 M

tonne/y in 2009. US demand formetallocene grades of polypropyleneare expected to rise by 30%/y from70,000 tonne/y in 2004 to 261,000tonne/y in 2009.

Plastics and Rubber Weekly, 15 Apr 2005, 16

Spanish HDS projects

The majority of projects currentlyunderway in the refining sector are forhydrodesulfurization (HDS) units thatproduce fuel with very low sulfurlevels. These fuels meet new EUenvironmental standards that arelisted in a table. HDS processesbasically comprise mixing streams offuel and hydrogen in the presence ofa catalyst that enables fueldesulfurization to occur. A tablecontains a list of companies thatlicence HDS technology. They includeABB Lummus, Axens, ExxonMobil,Haldor Topsoe, Howe-Baker, Linde,and UOP. Cepsa is currently investing€169 M in HDS units for its refineriesin Algeciras, Huelva, and Tenerife.Technology is being licensed fromAxens, UOP, and Haldor Topsoe.Repsol is investing €260 M in HDSprojects at its Bilbao and Petronorrefineries. A table containsinformation about HDS projects inSouth America involving theparticipation of Spanish companies.

Ingenieria Quimica, Dec 2004, (419), 75-77 (inSpanish)

Sinopec 2004: production andoperation: R&D

In 2004, Sinopec proactivelydeveloped core technology andproprietary technology for its principaloperations and achieved fruitfulresults with 639 domestic patents and48 foreign patents being granted.Breakthrough was achieved inexploration in marine phasesedimentary structure in southernChina. Additionally, the companysuccessfully developed technologiesto improve the recovery rate inoilfields having complex faultage,flexible and diversified FCCtechnology (FDFCC), sulfur removaland olefin content reductiontechnology through selectivehydrofining of catalytic gasoline(RIDOS), and 150,000 tonne/y three-reactor PET technology. Progresswas made in the construction of

information systems. ERP systemwas deployed at 23 entities and itsintegrated advantage became moreprominent. The comprehensive oilfieldmanagement system and the Ningbo-Shanghai-Nanjing crude oil pipelinetransportation and distributionmanagement system were completedand put into operation.

Sinopec Profits for FY 2004, 29 Mar 2005, 12(Sinopec Corp, Beijing, China, Website:http://www.sinopec.com.cn)

Biotechnology community watch:collaborations and acquisitions

During Jan-Feb 2005, fourteencollaborations and four acquisitionsinvolving North Carolinabiotechnology companies wereannounced.

BT Catalyst, Mar-Apr 2005, 19 (2), 4 (Website:http://www.ncbiotech.org/ncindustry/news/btcat/btcat.cfm)

COMPANYNEWS

Albemarle announces record 1Q 2005results

Albemarle Corp reported 1Q 2005 netincome, excluding special items, of$25.2 M, which was 53% higher than1Q 2004, due to strong performancein each of the company’s threebusiness segments. The companyreported record net sales of $510 Mfor 1Q 2005, up $188 M compared to1Q 2004, due in large part to the Jul2004 acquisition of the Akzo Nobelrefinery catalysts business. Catalystssegment net sales were $172.8 M, up$149.9 M versus 1Q 2004, due mainlyto the addition of the refinery catalystbusiness and strong sales ofhydroprocessing catalysts. R&Dexpenses were $10.98 M for 1Q 2005($4.579 M in 1Q 2004).

Albemarle 1Q 2005 results, 26 Apr 2005 (AlbemarleCorp, 330, South Fourth Street, PO Box 1335,Richmond, VA 23210, USA. Tel: +1 804 788 6000.Fax: +1 804 388 7686. Website:http://www.albemarle.com)

Basell raises the bar for gas-phase PEcatalysts

Basell Polyolefins has introducedAvant Z 230, a new generation ofZiegler titanium catalysts for use in

2 JUNE 2005

F O C U S O N C A T A L Y S T S