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Biotechnology Biotechnology Making the products you Making the products you buy. . . buy. . . better? better?

Biotechnology

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Biotechnology. Making the products you buy. . . better?. Historical Technologies: Applied Genetics. Manipulation of the hereditary characteristics of an organism to improve or create specific traits in offspring e.g., selective breeding, hybridization. - PowerPoint PPT Presentation

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  • BiotechnologyMaking the products you buy. . . better?

  • Historical Technologies: Applied GeneticsManipulation of the hereditary characteristics of an organism to improve or create specific traits in offspringe.g., selective breeding, hybridization

  • Historical Technologies: Applied GeneticsSelective breeding Allowing only those individuals with the desired traits to reproduce

  • Historical Technologies: Applied GeneticsHybridization crossing different individuals to bring together the best traits of both organisms Produces hybrid offspring that are often hardier than the parents

  • e.g., commercial chickensCommercial chicken:Grows to a large full size in only 6 weeks

  • Modern Technologies: Genetic EngineeringAltering an organisms genetic code (DNA) to get it to express desired traitshttp://images.google.com/imgres?imgurl=http://www.peaceproject.com/graphics/dvds/larger/DVD51.jpg&imgrefurl=http://www.peaceproject.com/books/dvd51.htm&h=425&w=301&sz=34&hl=en&start=4&tbnid=z2kXaaU36oWWsM:&tbnh=126&tbnw=89&prev=/images%3Fq%3Dgenetically%2Bmodified%26gbv%3D2%26hl%3Den%26safe%3Dactive%26sa%3DX

  • e.g., Bt cornBacillus thuringiensis (Bt): a bacterium that produces a caterpillar toxinThe gene for this toxin has been inserted into this corns genome, which causes it to produce the toxin

  • e.g., spider silkA spiders silk-making gene has been inserted into a goat, which then produces silk in its milkhttp://www.chm.bris.ac.uk/motm/spider/goat.jpghttp://www.kevhopgood.co.uk/New%20Stuff/Spider-Goat.jpghttp://rockgardn.easystorecreator.com/images/images_919/JRFJ-Front-LG.gif

  • http://www.jewishworldreview.com/toons/varvel/biotech.protest.gifhttp://www.bairesbiotec.org.ar/images/speake1.jpge.g., golden riceDaffodil genes for making beta-carotene are inserted into the genome of rice

  • e.g., human insulinPreviously, humans with diabetes used insulin derived from the pancreas of cows and pigs (limited production)Today, most human insulin comes from human insulin-making genes transferred into simple cells such as bacteria or bakers yeast (unlimited supply)Identical to insulin made by the human pancreas

  • Recombinant DNA in bacteriaRecombinant DNA taking a piece of one DNA and combining it with another strand of DNAOften, fast-growing single-celled organisms are usede.g., bacteriaA piece of DNA that codes for a protein we want more of (e.g., human insulin) is spliced into the DNA of the fast-growing organismhttp://img.blogcu.com/uploads/kedicikkopekcik_insrton.jpg

  • Modern Technologies: Genetic EngineeringGene therapy adding a corrected copy of a gene to a person with a mutated gene to treat a diseasee.g., Cystic FibrosisDoes NOT change the persons genetic code! Effect is temporary

  • Restriction Enzymes:Enzymes that cut DNA at certain sequences.http://www.accessexcellence.org/RC/VL/GG/images/restriction.gif