Biotech Industry in Switzerland

Swiss Life Sciences Database c/o Venture Valuation | Badenerstrasse 18 | 8004 Zürich | www.venturevaluation.ch | [email protected]

Biotech Industry in Switzerland

Swiss Life Sciences SurveyJune 2005

Provided by Swiss Life Sciences Database v/o Venture Valuationwww.swisslifesciences.com | www.venturevaluation.ch


Biotech IndustryIn Switzerland

Swiss Life Sciences Survey June 2005

Swiss Biotech Companies - Breakdown by Biotech Clusters

Comments: Total of 286 companies.

BioValley Basel 71

Greater Zurich Area 89

BioAlps 62

Other 44

Bioplolo Ticino 20




Swiss Biotech Companies - Breakdown by Subcategories

Comments: Based on the categorization of the Swiss Life Sciences Database; Total of 286 companies.

Other Services and Suppliers 17%Pharmaceuticals

and Chemicals 16%

Reagents and Compounds 6%

Diagnostics and Analytical Services

17%Drug Delivery 2%

Environment, AgroBio, Food 11%

Genomics and Proteomics 3%

Contract Research and Manufacturing

9%

Bioinformatics and Bioelectronics 6%

Therapeutics 13%

Source: www.swisslifesciences.com




Product Development of Swiss Biotech Companies - Breakdown by Development Phases

Comments: Based on the company profiles categorized as „Biotechnology“ (52 companies).

59

41

21

27

0 10 20 30 40 50 60

Discovery & Preclinical

Phase I/II

Phase III

NDA/on the market





Foundation of Swiss Biotech Companies 1995 – 2005 (YTD)Breakdown by Main Categories

Comments: Total 128 foundations between 1995 – 2005 (YTD).

4

1

2

4

3

3

8

2

6

11

4

2

4

2

7

10

2

5

10

3

9

3

3

2

6

3

4

2

21

0

5

10

15

20

25

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005(YTD)

Biotechnology Biotechnology Instrumentation & Services Biotechnology related





Size of Biotech Companies - Number of Employees

Comments: Data about employees available for 155 companies (total 286 companies).

101-200: 6%

201-400: 6%

21-30: 8%31-40: 6%

41-50: 1%

51-100: 14%

401-: 6%

1-10: 43%

11-20: 10%





Ownership of Swiss Biotech Companies - Breakdown Public / Private

Comments: Total 286 companies.

Public: 18

Private: 270


6 Public drug developmentBiotech companies (of totally 18 public companies in the Biotechnology/Pharma field):

- Actelion Ltd- Arpida AG- Basilea Pharmaceutica AG- Berna Biotech Ltd.- Cytos Biotechnology AG- Serono Internation SA




Source of FoundationSwiss Biotechnology Companies

Comments: Data available for 51 companies.

University / Institute Spinoff

62%

Company Spinoff

10%

Subsidiary20%

M&A8%





IPOs of Swiss Biotech & Medtech Companies2000 – 2005 (YTD)

Comments: Total8 IPOs between 2000-2005 (YTD).

0

1

2

3

4

2000 2001 2002 2003 2004 2005


Berna Biotech Cytos Biotechnology Basilea Pharmaceutica

ActelionGivaudan

IsoTis

Arpida




Biotechnology in selected EU countries

Comments: Based on information available on www.biotechgate.com

Austria France Italy Switzerland

Biotech Companies 53 204 195 286

Core Biotech Companies

13 84 33 52

New Comp. (2000-2004)

10 68 30 69

Up to 20 employee 48% 62% 50% 53%

# of clinical products 5 61 20 62


Key Characteristicson the Swiss Life Sciences Field

• Switzerland is a main Biotech cluster in the centre of Europe

• The country comprises top companies in the Pharma, Biotech and Medtech industry

• Switzerland has a high density of high class Universities

• Serono International SA (SWX: SEO) is the biggest Biotech company in Europe

• 6 public drug development Biotech companies

• Last IPO took place in May 2005 with Arpida AG




Additional Information available onwww.swisslifesciences.com




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Swiss Life Sciences SurveyJune 2005

The „Swiss Life Sciences Survey“ is based on the data entered in the Swiss Life Sciences Database available on www.swisslifesciences.com. The statitistics and graphs in this presentation include the figures and information entered in this database. We do not guarantee any accuracy hereof.

The use of the figures and graphs provided in this report is free of charge for any presentations only with the remark of reference „Source: www.swisslifesciences.com“. For all other uses please contact us for the terms of conditions.

Swiss Life Sciences Databasev/o Venture Valuation VV AGBadenerstrasse 18 +41 (43) 321 86 608004 Zurich [email protected] www.venturevaluation.ch

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Biotech Industry in Switzerland