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Biosensor Technologies
Page 2 Confidential
Johnson Medtech Biosensor Technology Overview
► Johnson Medtech biosensor technologies provide world-class design,
prototyping, and value added assembly for flexible circuits, printed
electronics, flat flexible cabling and microelectronics.
► Johnson Medtech has the broadest range of flexible interconnects, flex
circuits and sensor products to serve the global medical industry.
► Custom circuits are developed based on proprietary designs, processes
and materials including dielectrics, conductors, printed electronics
technology and the expert formulation of inks.
► We provide unique microelectronic design and solutions as an integral
part of our customers’ advanced system products.
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Johnson Medtech Biosensor Products
► Applications
– ECG Sensors
– Microfluidic Sensors
► Technology Leadership
– Custom-engineered solutions
– Superior signal integrity
– Testing accuracy
– High precision
– Ease-of-use
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Technology Print Electronic
Additive Printing
Subtractive Printing
Data Acquisition &
Accuracy
Good
(Electrochemical)
Good
(Electrochemical)
Thickness Very thin (0.4 mm) Thin (1.1 mm)
Production Process
Waste
Low (0% waste / 100%
utilized)
High (15% etched away)
Layer Configuration Single Sided, Double-
Sided, Multi-Layer
Single Sided, Double
Sided, Multi-Layer
Sensor Flexibility Curvable, Integration of
circuit & interconnects
Curved, Integration of
circuit & interconnects
Environmental
Concern
RoHS compliance RoHS compliance
Print Electronic (PE) Technology
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Johnson Medtech ECG Disposable Sensors
► Safe Choice
– Industry leader in biosensor technology
– Testing accuracy
– Stability when exposed to human body fluid
– Over 20 years medical device experience
► Technology Leadership
– Unique AgCI conductor
– Customized conductivity
– Most conductive low impedance gel
– Superior signal integrity
– Ease-of-use
ECG Sensors ECG Sensor Applications
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Johnson Medtech Microfluidic Sensors
► Safe Choice
– Testing accuracy
– Precise sensor printing
– Precision channel cutting
– Industry leader in biosensor technology
► Technology Leadership
– Custom-engineers solutions
– Integrated hydrophilic electrode / sensor
– Best fluid spread-ability
– Ease-of-use
Microfluidic Sensor Microfluidic Application
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Construction of Microfluidic Sensors
(Print Electronic Technology)
Cover Layer
With circuit layout
Microfluidic Sensor
Blood
entry Enzyme or reagents Vents
Pre-cut Channels
Reaction Zone
`
Spacer Layer
Electrode Layer
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Blood Flow in Microfluidic Sensors
► The print electronic (PE) technology allows improvements in testing accuracy, consistency and total sensor cost in four areas:-
► Electrode thickness
► Electrode surface roughness
► Electrode edge irregularity
► Electrode spacing
Electrode 1
Electrode 2
Blood flow
Channel
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Electrode Thickness
► Reduced thickness can drive material cost saving and enable thinner microfluidic channel for lower sample volume.
Parlex
(Cross-Section View)
Others
(Cross-Section View)
Electrode (Avg. 7.0 µm*)
* Average values in 40 measurements
Electrode (Avg. 13.9 µm*)
Potting Epoxy Potting Epoxy
PET PET
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Electrode Surface Roughness
► Reduced surface roughness leads to uniform blood flow.
Johnson Medtech Others
19.0 μm 8.0 μm
Electrode
PET
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► Reduced edge irregularity to improve electrode spacing consistency for accurate impedance results.
Electrode Edge Irregularity
Johnson Medtech
(Top View) Others
(Top View)
40.5 μm 16.5 μm
Substrate
Electrode
Substrate
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Electrode Spacing
► As gap between electrodes affect impedance value, this is important to maintain consistent spacing when printing is made.
Electrode Parlex Others
Spacing (mm)* 1.90 to 1.92
(1% variation)
1.94 to 2.00
(2% variation)
Electrode
Spacing
* Measurement: 10 parts / 20 data points
Electrode ink
Electrode ink
Substrate
(Top View)
Page 13 Confidential
Johnson Medtech Biosensor Technology
► Technology Leadership
– Custom-engineered solutions
– Custom printed electronics
– Unique printing technology
– High precision
► Safe Choice
– Superior signal integrity
– Highly accurate testing for improved clinical outcomes
– Industry leader in biosensor technology
