Biosecurity solutions

survey, Detect, Analyze, respond.Address biological and chemical threats with confidence

this Brochure is not for DistriBution in the uniteD stAtes

Applied intelligence. improved confidence.

While no single detection method can meet all these challenges, there are powerful new technologies in place today that can help protect the public from emerging biological and chemical threats. now, Applied Biosystems offers leading-edge analytical technologies and integrated systems that provide rapid, accurate and actionable information on natural and manmade pathogenic organisms, explosives, poisons, and other hazardous materials.

As concerns about biological and chemical security threats increase worldwide, so does the need for early warning systems capable of providing timely and accurate intelligence— but there are significant challenges. Biological and chemical threats are difficult to predict or prevent, they come in many forms, and they can spread quickly without warning.

today’s world requires that health agencies and security professionals have the tools and information they need to respond to natural and man-made chemical and biological threats. Applied Biosystems has the systems and expertise to meet this need and is committed to making these resources available to laboratories throughout the world.

tested in the lab, proven in the field.

coMPlete solutions

to respond effectively to biosecurity threats, it is critical to have immediate access to reliable platforms that can rapidly detect and identify potential risks. sensitivity and specificity of tests are also key factors, as well as the flexibility to detect known, modified, and previously uncharacterized agents in complex samples accurately. Applied Biosystems integrated biosecurity solutions combine standardized protocols, optimized reagent kits, proven software, and validated instrumentation capable of detecting and tracking threats regardless of form or source.

Applied Biosystems offers solutions in areas critical to biosecurity.

Make early detection a reality. Applied Biosystems/MDs scieX mass spectrometry systems can characterize chemical threats such as explosives and water contaminants in minutes. Applied Biosystems real-time Pcr systems reliably detect high risk pathogens using proven taqMan® assay chemistry.

Accurately identify and characterize biological and chemical pathogens. Applied Biosystems genetic analyzers provide detailed information on pathogenic bacteria, viruses, and fungi. this information is invaluable in tracking mutations in rapidly evolving organisms. nA-Star™ chemi-luminescent kits can determine resistance to substances used in antiviral research.

lead the drive to protect the public from biosecurity threats. Applied Biosystems integrated biosecurity solutions provide rapid, reliable results that enable public officials to respond to threats quickly and effectively.

Ambion MagMAX™ kits deliver high throughput and manual sample processing at laboratories around the world.

national public health networks use Applied Biosystems/MDs scieX mass spectrometers for chemical threat detection and real-time Pcr systems for biological threat detection.

researchers throughout the world use Applied Biosystems leading technology to sequence and study the genomes of pathogenic organisms such as the avian flu, sArs, and West nile viruses.

in response to the call for a fast and reliable early warning system for avian influenza, Applied Biosystems taqMan® influenza Detection Kits can detect the presence of the avian influenza virus in as little as 2.5 hours.

End-to-end solutions, ready for deploymentApplied Biosystems Biosecurity solutions are available today to meet critical needs in biosecurity, backed by service, support and training from knowledgeable experts who are ready to provide assistance and consultation around the world.

SurvEy

DEtEct

AnAlyzE

rESponD

3130xl / 3730xl Genetic Analyzers

taqMan® Influenza A/H5 Detection Kit

nA-Star ™ Kits

7500 FASt real-time pcr System

Sample collection | Sample preparation

Biological threats | chemical threats

pathogens | chemical compounds

Decontamination Assessment | new Assay Development | prevention

MagMAX™ System

screen for potential threats with high confidence. Applied Biosystems Ambion MagMAX™ kits are fast, easy-to-use, versatile, and offer streamlined sample preparation methods that minimize hands-on time.

ApI 3200™ lc/MS/MS System

At Applied Biosystems, we recognize that routine standardized testing is the key to rapid and reliable detection and containment of biosecurity threats. We offer biosecurity solutions that include standardized sample preparation procedures, specialized reagent kits and systems, and testing protocols. our biosecurity specialists work closely with you to ensure that your operators are thoroughly trained, your systems are correctly configured and installed, and your tests are producing accurate, reliable results.

coMPrehensive suPPort

on the front lines of biosecurity testing.

large-scale, iso accredited manufacturing facilities in the u.s. and the united Kingdom and major distribution centers in singapore, Japan, the netherlands and Australia give Applied Biosystems the capacity to produce and distribute large quantities of high quality assays quickly.

Dedicated support professionalsthrough Applied Biosystems, you have access to the most comprehensive global technical service and support organization available, with over 480 staff professionals who are trained to keep your system running at peak performance. We provide you with specialized training, service, and applications assistance on-site,over the phone, and on-line.

• Applied Biosystems has an installed base of thousands of real-time Pcr platforms in public health facilities around the world capable of running biosecurity tests.

• over 12,000 Applied Biosystems genetic analyzers are installed in 4,500 locations worldwide.

• Applied Biosystems delivers reagents for millions of tests for anthrax and other pathogens to the u.s. Postal service, u.s. Department of Defense and government agencies around the world.

• Applied Biosystems provides instruments that form the backbone of the surveillance network for various disease-causing pathogens throughout the united states, europe and Asia.

• Applied Biosystems Ambion MagMAX™ kits were vital for processing thousands of samples during an outbreak of exotic newcastle Disease in the united states.

• Applied Biosystems MDs/scieX APi 4000™ lc/Ms/Ms system has been selected by national public health networks to aid in the detection of chemical threats.

• Applied Biosystems 7500 real-time Pcr instrument and influenza Kits provide front-line Avian influenza surveillance for the Department of Agriculture in indonesia.

Biosecurity expertise and infrastructure

Headquarters 850 lincoln centre Drive | foster city, cA 94404 usA Phone 650.638.5800 | toll free 800.345.5224 www.appliedbiosystems.com

International Sales for our office locations please call the division headquarters or refer to our Web site at www.appliedbiosystems.com/about/offices.cfm

these products and data obtained from use of these products should not be used for human diagnostic, human treatment or other clinical purposes, or for personal, family or household purposes. these products have not been cleared or otherwise approved by the united states food and Drug Administration or any other regulatory agency for human diagnostic, human treatment or any other clinical purpose. these products are for research use only. not for use in diagnostic procedures.

© copyright 2007, Applied Biosystems. All rights reserved. Please refer to the product user’s guide or package inserts for limited label license, terms and limitations of use and other important product information. AB (Design), Applera, and Applied Biosystems are registered trademarks and nA-Star is a trademark of Applera corporation or its subsidiaries in the u.s. and/or certain other countries. MagMAX is a registered trademark of Ambion, inc., an Applied Biosystems Business. APi 3200 and APi 4000 are trademarks of Applied Biosystems/MDs scieX, a joint venture of Applera corporation and MDs, inc. taqMan is a registered trademark of roche Molecular systems, inc.

Printed in the usA, 1/2007 Publication 116Br04-01

in 2005, Applied Biosystems announced a comprehensive program for responding to the avian influenza threat that includes standardized detection kits and access to influenza virus sequencing information. this program is part of a global Applied Biosystems initiative to help protect the public from emerging natural and man-made biosecurity threats. By combining scientific expertise, genetic analysis systems, and assay development with global distribution channels, Applied Biosystems delivers standardized and reliable biosecurity solutions to public health organizations throughout the world.

for more information on the Applied Biosystems Global surveillance initiative and Biosecurity solutions, please call the Applied Biosystems representative nearest you, or visit www.appliedbiosystems.com/biosecurity

the Applied Biosystems Global surveillance initiative.

this Brochure is not for DistriBution in the uniteD stAtes