BIOMEDICAL RESEARCH INSTITUTE

FOUNDATION FOR RESEARCH & TECHNOLOGY- HELLAS

BRI - FORTH

Legal Framework

1998- Establishment of “Ioannina Biomedical Research Institute” (IBRI) as an autonomous Institute, under the auspices of General Secretariat for Research and Technology, Ministry of Development

2001- Merger with “Foundation for Research and Technology-Hellas” (FORTH) New legal name: “Biomedical Research Institute / Foundation for Research and Technology-Hellas” (BRI-FORTH)

1-1-2002- Financial & Administrative merger with FORTH

Administration & Personnel

Director: Prof. Efthimios Kaxiras, Dep. of Materials Science & Engineering, University of Ioannina

Deputy Director: Prof. Theodore Fotsis, Lab. of Biological Chemistry, University of Ioannina

Institute Honorary Fellows: Prof. Christos Massalas, Dep. of Materials Science & Engineering, University of Ioannina

Researchers: Dr. Carol Murphy (Rank B)

Administrative Officer: Ms. Ioanna MpempiAccountant: Mr. Charalampos KalogeropoulosAccountant: Ms. Basiliki GoudaTechnician: Mr. Georgios Bellos

Collaborating Faculty Members

Georgatos, Spyros, Prof., Medical School, U.I.

Evaggelakis, George, Assoc. Prof, Dep. of Physics, U.I.

Zonios, George, Assist. Prof., Dep. of Materials Science &

Engineering, U.I.

Ioannidis, John, Prof., Dep. of Epidemiology, U.I.

Lagaris, Isaak, Prof., Dep. of Computer Science, U.I.

Likas, Aristidis, Assist. Prof., Dep. of Computer Science, U.I.

Floudas, George, Assoc. Prof., Dep. of Physics, U.I.

Fotiadis, Dimitrios, Assoc. Prof. Dep. of Computer Science, U.I.

Christoforidis, Savvas, Lecturer, Medical School, U.I.

Papamarkaki, Thomais, Assist. Prof, Lab. of Biological Chemistry, U.I.

Personnel in Research Projects(Period 2001-2004)

52 Researchers with work contracts

22 Postgraduate Students

Premises

BRI-FORTH doesn’t have atpresent its own building:

Secretariat & Accounting Room:

hosted by Medical School

Laboratory of Dr. C. Murphy: hosted by Laboratory of Biological Chemistry, U.I.

Laboratories of Biomedical Technology: hosted by Dep. of Computer Science, Dep. of Materials Science & Engineering, U.I.

Laboratory of Epidemiology: hosted by Medical School, U.I.

Equipment and funding (period 2000-2004

Equipment purchase: 1.470.600 Euros, funded by GSRT:

- Biochemistry-Molecular Biology: 970.600 Euro

- Biomedical Technology: 500.000 Euro

Funded Competitive Projects: - Competitive Projects E.U : 2.172.108

Euro -Competitive Projects GSRT: 162.553

Euro -Other Projects:

80.000Euro

Completed projects (period 2000-2004)

PLACEBO, “An Innovative Computational Platform for Solving Differential Equations in Modeling Biomedical Processes”, EU (IST)

h-Life, “Intelligent Personal Health Assistant”, EU (IST)

Active Health, “Active Environment for Health Promotion and Disease Prevention”, EU (IST)

CITATION, “Citizen Information Tool in Smart Administrations”, EU (IST)

US Bone, “A Remotely Monitored Wearable Ultrasound Device for the Monitoring and Acceleration of Bone Healing”, EU (IST)

DROMEAS-A Wearable Platform for the Monitoring of Health Condition and Sport Performance of Athletes and the Real Time Prevention of Sport Injuries, EPISEY (Subcontracting) (IST)

“Nearest-neighbour relationships of emerin, LAP2beta, and I.BR: a key to understanding the molecular basis of "envelopathies”, Association Francaise contra les Myopathies

Projects in progress (period 2000-2004)

“Global Genetics Consortium: Collaborative pooled analysis on the association of the alpha-synuclein gene REP1 variant and Parkinson's disease”, Michael J. Fox Foundation

“Empo Young Investigator”, EMBO

“Towards a process for ventilating air sterilization”, Joint Research and Technology Programmes 2004-2006, GSRT

“Signal transduction and membrane trafficking in endothelial cells”, GSRT, PENED 2001

Intelligent, “Human Network for the study and dissemination of the use of intelligent transplants and artificial organs in Medicine”, GSRT, EPAN-HUMAN NETWORKS

Events and seminars (period 2000-2004)

Events:6th Meeting of FORTH Researchers (1-3/3/02 Ioannina-Metsovo)

Informative Meeting (U.I, BRI-FORTH, Industrial Property Organization, Network “PRAXI”, 14-15/11/02 Ioannina)

Conference in the framework of Hellenic Presidency of E.U.:" Foresight in the Enlarged European Research & Innovation Area"(GSRT, BRI-FORTH 15-16/5/03 Ioannina)

6h International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering (18-21/9/03 Tsepelovo)

Symposium "Molecular epidemiology of Parkinson's disease: the Global Genetics Consortium” (Dep. of Hygiene and Epidemiology, U.I, BRI –FORTH, 22/9/2004)

Mini-symposium "Membrane trafficking"(BRI –FORTH, Lab. of Biological Chemistry, Medical School, U.I, 23 –25/4/04)

Seminars: 20

Objectives & Prospects for 2005-2008

PremisesRenovation of a 800 s.m. buildingusing funds from Region of Epirus, 455.000 euroA new building will be constructed in a lot provided by U.I.

Laboratory equipment for research teams

Expanding- renewal of laboratory equipment from:Structural Programs Government Operational ProgramsCommunity Support Framework III Operational Programs

Objectives & Prospects for 2005-2008

Staffing according the budget 2004 (261.337 euro):

Hiring of 4 new Researchers

Research Directions:Molecular mechanisms of Cell functionComputational BiologyBioinformatics-ModelingEpidemiologyBiophysics Applications

Collaboration is necessary: Medicine, Biology, Chemistry, Physics,

Science of Materials, Computer Science, Applied Mathematics

Endothelial-smooth muscle cell interactions

Stages of angiogenesis

Haematopoetic stem, progenitors and precursor cells co-mobilize with CEPs

Νεοπλασματική αγγειογένεση: Μοριακοί μηχανισμοί και εφαρμογές

Ενδοθηλιακάκύτταρα

Αγγειογενετικοίπαράγοντες

Νέα αγγεία:Αύξηση του όγκου

Περισσότερα αγγεία:Παραπέρα αύξηση του όγκου -μετάσταση

Αντιαγγειογενετική θεραπεία

Υποστροφή του όγκου

Medicine

BRI-FORTH

Chemistry

Physics

ComputerScience

Biology

MaterialScience