Biomedical Informatics Update 2012

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    a New York State Center for Advanced Technology at Columbia University

    February 2, 2012Pfizer Headquarters219 E 42nd St., New York, NYConference Room (ground floor)

    Biomedical Informatics Update 2012

    A one-day meeting for local and regional healthcare

    specialists to discuss advances, problems, and

    solutions in various medical informatics venues in the

    New York area. The session will provide an opportunity

    to meet and talk to leading specialists who are at the

    forefront of HIT practice and innovation.

    This event is organized by Columbia University'sCenter for Advanced Information Management* and

    Department of Biomedical Informatics and is hosted by

    Pfizer Healthcare Informatics.

    *The Center for Advanced Information Management at Columbia University is a NYSTAR-sponsored Center for Advanced Technology

    630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196WWW.CAT.COLUMBIA.EDU

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    12:00pm LUNCH

    Program Schedule

    Time Event

    8:30am Coffee, Pastries

    9:00am Welcome and Introductions

    Michael Cantor, MD, MA; Pfizer, Inc.

    Update OverviewGeorge Hripcsak, MD, MS; Columbia University

    Remarks on New York City Biomedical TechnologySeth W. PinskyNYC Economic Development Corporation

    2:15pm Looking to the Future: Biomedical Informatics Research, Training, and PracticeEdward H. Shortliffe, MD, PhD

    9:45am

    1:00pm

    Where Are We With Implementing Health Information Exchange?Gilad Kuperman, MD, PhD

    Watsons Potential Impact on Medical Practice Part A: Herbert S. Chase, MD, MA Part B: Roberto Sicconi, Dr. Ing. Demo and Q/A Session

    10:45am An Update on the Primary Care Information Project and Population Health in NYCJesse Singer, DO, MPH

    11:15am Evaluation of HIE Implementation: New Methods and Results from HEAL NY Phase 5

    Jacqueline Merrill, RN, MPH, DNSc

    3:00pm Speaker/Attendee Mixer

    February 2, 2012Pfizer Headquarters219 E 42nd St., New York, NYConference Room (ground floor)

    1:45pm Update on PACeR [Partnership to Advance Clinical Electronic Research]David A. Krusch, MD

    10:15am BREAK

    9:15am Electronic Medical Records, Biobanks, and Personalized MedicineErwin Bottinger, MD

    630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196WWW.CAT.COLUMBI A.EDU

    Biomedical Informatics Update 2012

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    Speakers Profiles

    630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196WWW.CAT.COLUMBIA.EDU

    Michael N. Cantor, MD, MA, FACP

    Senior Director, Pfizer Biomedical Informatics ServicesPfizer, Inc.

    Michaels work at Pfizer focuses on finding innovative

    uses for clinical data; precision medicine; and drug

    safety. He also co-leads the Data Without Borders

    initiative within Pfizers Worldwide

    R&D Business Technology organization. Prior to

    joining Pfizer he was the Chief Medical Information Officer for the

    South Manhattan Network of NYCs Health and Hospitals

    Corporation, based at Bellevue Hospital in Manhattan. Trained as

    an internist, he continues to see patients at Bellevue and is a

    Clinical Assistant Professor of Medicine at NYU School of Medicine.

    He completed his residency and informatics (MA) training at the

    Columbia campus of New York Presbyterian Hospital.

    George Hripcsak, MD, MSVivian Beaumont Allen Professor and Chair of Biomedical Informatics

    Director, Center for Advanced Information ManagementColumbia University

    In addition to his Columbia roles, George is also

    Director of Medical Informatics Services for

    NewYork-Presbyterian Hospital. He is a board-

    certified internist with degrees in chemistry,

    medicine, and biostatistics. He led the effort to

    create the Arden Syntax, a language for representing health

    knowledge that has become a national standard. Dr. Hripcsaks

    current research focus is on the clinical information stored inelectronic health records.

    Using data mining techniques such as machine learning and natural

    language processing, he is developing the methods necessary to

    support clinical research and patient safety initiatives. As Director of

    Medical Informatics Services, he oversees a 7000-user, 3-million-

    patient clinical information system and data repository.

    He is currently co-chair of the Meaningful Use Workgroup of

    HHSs Office of the National Coordinator of Health Information

    Technology. Its role is to define the criteria by which health care

    providers collect incentives for using electronic health records.

    Dr. Hripcsak was elected fellow of the American College of

    Medical Informatics in 1995 and served on the Board of Directorsof the American Medical Informatics Association (AMIA). As chair

    of the AMIA Standards Committee, he coordinated the medical-

    informatics community response to the Department of Health and

    Human Services for the health-informatics standards rules under

    the Health Insurance Portability and Accountability Act of 1996.

    Dr. Hripcsak chaired the National Library of Medicines Biomedi-

    cal Library and Informatics Review Committee, and he is a fellow

    of the American College of Medical Informatics and the New York

    Academy of Medicine. He has served on several Institute of

    Medicine and National Academy of Sciences committees, and he

    has published over 200 papers.

    Erwin P. Bottinger, MDDirector, Charles R. Bronfman Institute for Personalized Medicine

    Professor, Nephrology and Professor, Pharmacology andSystems Therapeutics

    Mt. Sinai School of Medicine

    Dr. Bottinger is a trained nephrologist and

    experimental biologist, and holds the Irene and Dr.

    Arthur Fishberg Professor of Medicine endowed chair

    at Mount Sinai School of Medicine since 2004. His

    research focuses on exploring and evaluating the

    translation of genetic and molecular information in medical

    practice. He is the Director of the Charles R. Bronfman Institute for

    Personalized Medicine at Mount Sinai and the principal architect of

    the Institutes Biobank since 2007. He served previously as Vice

    Chair for Research, Department of Medicine. In addition, Dr.

    Bottinger holds NIH-funded research grants in the area of

    mechanisms of kidney disease and diabetic complications.

    Dr. Bottinger was previously an Associate Professor of Medicine

    and Molecular Genetics at Albert Einstein College of Medicine in

    Bronx, New York, for six years. During his tenure at Albert Einstein

    he also held several hospital appointments, including Attending

    Physician in the Department of Medicine at Montefiore Medical

    Center and Jacobi Medical Center in the Bronx. Dr. Bottinger also

    served as Visiting Associate at the National Cancer Institute and

    Visiting Staff Physician in the Kidney Disease Section at the Warren

    Grant Magnuson Clinical Research Center of the National

    Institutes of Health in Bethesda, Maryland.

    Dr. Bottinger has published many scientific studies and has

    received several awards, including the Special Service Award fromthe National Cancer Institute and the Mellini Award for Excellence

    in Biomedical Sciences. In 2002, he was elected a member of the

    American Society for Clinical Investigation.

    Trained in Europe, Dr. Bottinger received his medical degree from

    Friedrich-Alexander Universitat School of Medicine in Erlangen,

    Germany. He moved to New York to pursue a residency in internal

    medicine at Cabrini Medical Center and later completed a clinical

    and research fellowship in nephrology at Massachusetts General

    Hospital and Harvard Medical School in Boston. In addition, he

    served as a research fellow at the National Cancer Institute, where

    he stayed on as a Visiting Associate for four more years. Dr.

    Bottinger joined Mount Sinai in 2004.

    Pfizer Host

    CAIM Host

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    Speakers Profiles (cont.)

    630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196WWW.CAT.COLUMBIA.EDU

    Herbert Chase, MD, MAProfessor of Clinical Medicine (in Biomedical Informatics)

    Columbia University

    For over thirty years, Herb Chase has been teachingclinical medicine and basic science to medicalstudents, interns and residents, and junior andsenior faculty at the Columbia University College ofPhysicians and Surgeons. He is a board certified

    Internist and Nephrologist who spent the early part of his career asa basic scientist. After shifting his interest from research toeducation, he directed and participated in several major medicalschool courses.

    In 2000 he left Columbia University and was appointed the firstDeputy Dean for Education at Yale School of Medicine where heintroduced several major programmatic changes. In 2006 hereturned to Columbia to enter the Masters program in Biomedical

    Informatics as an NLM-funded Postdoctoral Fellow. Dr. Chase hasbeen recognized for his outstanding teaching with many awardsincluding the Presidential Teaching Award of Columbia University.

    Dr. Chase is currently a Professor of Clinical Medicine (in Biomedi-cal Informatics) involved in several research projects: developinginformatics methods to detect chronic kidney disease in its earlieststages; developing just-in-time information-retrieval systems forclinicians at the point of care; implementing strategies forpharmacovigilance operating through the electronic medical record(EHR); and creation of a patient record summary in the EHR.

    He is the Principle Investigator on a $3.7 million grant, fundedthrough the Office of the National Coordinator, for University-Based Training of Health Information Technology Professionals.

    He is also a medical advisor to the IBM team developing themedical version of Watson. He continues to develop new medicaleducational programs at Columbia where he is now implementinga four-year curriculum in medical decision-making and a capstonecourse in Biomedical Informatics.

    David A. Krusch, MDDirector - Department of Medical InformaticsProfessor - Department of Surgery, Oncology and Professor -Department of Medical InformaticsUniversity of Rochester Medical Center

    Dave received his M.D. from the Johns Hopkins

    School of Medicine and then completed his residency

    and fellowship in surgery at the University of Virginia.His areas of specialty interest include gastrointestinal

    surgery, minimally invasive upper abdominal surgery, vascular

    access and surgical treatment of hematological diseases. Dr.

    Krusch is also the Director of the Department of Medical Informat-

    ics and the Chief Medical Information Officer.

    He has received several awards and honors, including the

    University of Rochester Medical Center Board Award for Excellence,

    2003; Buswell Fellowship Award, University of Rochester School of

    Medicine and Dentistry University of Rochester School of Medicine

    and Dentistry, 1993; The Bigger-Lehman Award, Virginia Surgical

    Society Virginia Surgical Society.

    Jacqueline Merrill, RN, MPH, DNScAssociate Professor of Clinical Nursing in Biomedical Informatics

    Co-Investigator, HITEC (Health Information TechnologyCollaborative)Associate Clinical Director, Center for Advanced InformationManagementColumbia University

    Jackie is a public health nurse and public healthservices researcher. She holds a doctorate in nursingscience with a concentration in public healthinformatics. Dr. Merrills public health experienceincludes six years with the New York City Department

    of Health and Mental Hygiene in the Bureau of School Health andthe Office of Nursing and Quality Improvement. Prior to earningher doctorate she spent four years as project director of the Centerfor Health Policy, at the Columbia University School of Nursing. As

    a result of her experience in clinical care, public health practice, andpolicy research, she has a broad knowledge of healthcare issuesand particular understanding of health information technology as itrelates to public health systems.

    Dr. Merrills research is based on a complex adaptive systemsparadigm. She works with local public health departments toimprove organizational performance. This work applies networkanalysis and management science to provide evidence-baseddecision support for public health managers.

    In October, Dr. Merrill completed an evaluation of the public healthuse cases implemented in Phase 5 of the Health Care Efficiency andAffordability Law for New Yorkers (HEAL-NY) Capital GrantProgram. The goal of this multi-year program is to transform healthcare in NYS, in large part through health information technology. Dr.

    Merrills evaluation was part of the Health Information TechnologyEvaluation Collaborative (HITEC), the academic consortium led byWeill Cornell Medical College, which is the designated evaluationentity for health IT projects funded under the HEAL-NY initiative

    Gilad J. Kuperman, MD, PhDExecutive Director, NYCLIXDirector, Interoperability Informatics, NewYork-PresbyterianHospital; Adjunct Associate Professor, Department ofBiomedical Informatics, Columbia University

    Gil is Executive Director of NYCLIX, a healthinformation exchange organization that coversManhattan and other parts of New York City. He is

    also Director for Interoperability Informatics atNewYork-Presbyterian Hospital. His role there is tohelp the hospital realize the benefits of interoperability internally,with its business partners and through participation in regionaldata interchange efforts.

    Dr. Kuperman is an Adjunct Associate Professor of BiomedicalInformatics at Columbia University. He will be the Board Chair ofthe American Medical Informatics Association, AMIA, in 2012 and2013. In 2010, he was Scientific Program Committee chair for theAMIA Annual Symposium, a conference on informatics whichdraws over 2000 people annually.

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    Speakers Profiles (cont.)

    630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196WWW.CAT.COLUMBIA.EDU

    Edward H. Shortliffe, MD, PhD, MACP, FACMIPresident and CEO,

    American Medical Informatics Association (AMIA)

    Ted Shortliffe is President and CEO of the American

    Medical Informatics Association, based in Bethesda,

    MD. His academic appointment is as Adjunct

    Professor of Biomedical Informatics at Columbia

    Universitys College of Physicians and Surgeons.

    Previously he was Professor of Biomedical Informatics at the

    University of Texas Health Science Center in Houston and, before

    that, at Arizona State University. He also served as the founding

    dean of the Phoenix campus of the University of Arizonas College

    of Medicine. From 2000-2007 he was the Rolf A. Scholdager

    Professor and Chair of the Department of Biomedical Informatics

    at Columbia University and Professor of Medicine and of

    Computer Science at Stanford University (1979-2000).Dr. Shortliffe has spearheaded the formation and evolution of

    graduate degree programs in biomedical informatics at Stanford,

    Columbia, and Arizona State University.

    His research interests include the broad range of issues related to

    integrated decision-support systems, their effective implementa-

    tion, and the role of the Internet in health care. He is an elected

    member of the Institute of Medicine, the American Society for

    Clinical Investigation, and the Association of American Physicians.

    He has also been elected to fellowship in the American College of

    Medical Informatics and the American Association for Artificial

    Intelligence. A Master of the American College of Physicians, he

    received the Grace Murray Hopper Award of the Association for

    Computing Machinery in 1976. Currently Editor-in-Chief of the

    Journal of Biomedical Informatics, Dr. Shortliffe has authored over300 articles and books in the fields of biomedical computing and

    artificial intelligence.

    Roberto Sicconi, Dr. Ing.Program Director

    IBM T.J. Watson Research

    Roberto received his MS degree from the Politecnico

    University of Milan, Italy and his Doctorate degree

    from the same University in 1985 in the area of

    image processing and new Computer Aided Design

    techniques.

    He joined IBM Italy in 1985 to work on development of multimediaplatforms, both hardware and software, working on hardware

    acceleration for hi-resolution PC and RISC/6000 workstations,

    DSP-based front-ends for IBM speech recognitions systems on

    PCs, PS/2 and laptops. In 1990 he became manager of the

    Multimedia Development Lab at Vimercate, Italy, leading

    development of speech recognition products (Martin/Voicetype),

    high-throughput bank check image scanners, a high-resolution

    negative film scanner, TV-Teletext VBI receivers, high-speed

    modems, a satellite Internet data broadcasting system, IBM

    cryptographic systems for data security, a portable

    videoconferencing system for laptops. In 1998 he moved to the

    US to work as executive assistant to the GM of IBMMicroelectronics, leading two cooperation projects with IBM

    Research (a speech chip and a Bluetooth chip).

    Dr. Ing Sicconi joined the Human Language Technology group at

    IBM T. J. Watson Research Center in 2000. There he managed

    development of exploratory prototypes of conversational and

    multimodal user interfaces in smartphones and other consumer

    devices (STB, videogames), with a special focus on cars, both in

    standalone and in network-connected configurations.

    Most recently he joined the DeepQA team to apply deep semantic

    analysis of very large unstructured information sources,

    hypotheses generation, multiple search and results scoring

    techniques to the Jeopardy! game and business Question

    Answering applications. Research projects are currently targeting

    differential diagnosis assistance in healthcare, technical support

    for agents in contact centers, customer technical support in

    financial services, and online videogaming. He coordinated

    speech activities and graphics display of the Watson avatar as part

    of the Jeopardy! Challenge.

    Jesse Singer, DO, MPHAssistant Commissioner for the Primary Care Information Project (PCIP)

    NYC Department of Health & Mental Hygiene (DOHMH).

    Jesse is board certified in Public Health and

    Preventive Medicine. He joined PCIP in 2007 as the

    Director of Quality Informatics and in 2009 became

    PCIP's Executive Director of Development. He wasresponsible for overseeing the collaborations

    between health information technology vendors and

    PCIP to incorporate public health priorities and functions into

    these products. Such functions include quality measurement and

    population health surveillance, clinical decision support, health

    information exchange and interfaces with public health agencies.

    Dr. Singer is a frequent presenter and panelist, focusing on health

    information technology (HIT) as a means to improve public

    health. He conceptualized and led the development of the Hub, an

    innovative model for improving public health through a system

    integrated with EHRs, allowing rapid deployment of public health

    queries, a clinical decision support system, and secure provider

    communication. This system currently covers close to 2 million

    patients in NYC. PCIP received the 2011 HIMSS Public HealthDavies Award of Excellence for its positive impact on population

    health through HIT innovations such as the Hub.

    continued >

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    Organizational Profiles

    Center for Advanced Information Management630 West 168th Street, PH 1501, New York NY 10032 Telephone: 212 305-2944 www.cat.columbia.edu

    In 1983, New York State established a Center for Advanced Technology (CAT) Program to promote the collaboration between its

    industry base and its major research institutions. The goal was to facilitate technology transfer and commercialization using the

    expertise and resources in academia to benefit companies economically.

    Currently, the program continues with 15 CATs at 13 institutions located around the state. Each CAT has a specific technology

    focus (http://www.nystar.state.ny.us/cats.htm) and approach to helping its partner companies. The CAT program is supported by

    Empire State Development, Division of Science, Technology and Innovation (a.k.a. NYSTAR). NYSTAR currently offers a range of

    programs to help promote the states technology base.

    Columbia Universitys Center for Advanced Information Management has been a participant in the CAT program since its

    inception. CAIMs focus is at the intersection of biomedical science, information technology, and biomedical imaging, with the

    occasional inclusion of other areas of biomedicine and information processing. Its main contributing units are the Department of

    Biomedical Informatics and the Center for Computational Biology and Bioinformatics, both at the medical center (College of

    Physicians and Surgeons), and the Computer Science Department and imaging group of the Department of Biomedical Engineer-

    ing, both in the School of Engineering and Applied Science. This broad range of expertise serves CAIM well in allowing for

    innovative interdisciplinary projects involving specialists from both schools and campuses.

    a New York State Center for Advanced Technology at Columbia University

    Pfizer Incorporated

    Pfizer applies science and its global resources to improve health and well-being at every stage of life. It strives to set the standard

    for quality, safety and value in the discovery, development and manufacturing of medicines for people and animals. Pfizers

    diversified global health care portfolio includes human and animal biologic and small molecule medicines and vaccines, as well as

    nutritional products and many of the world's best-known consumer products.

    Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that

    challenge the most feared diseases of our time. Consistent with its responsibility as the world's leading biopharmaceutical

    company, Pfizer also collaborates with health care providers, governments and local communities to support and expand access

    to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who

    rely on it. To learn more, please visit www.pfizer.com.

    Pfizer has co-sponsored the medical informatics update since its inception.

    Department of Biomedical Informatics622 West 168th St. VC5, New York, NY 10032 Telephone: 212 305-5334

    www.dbmi.columbia.edu

    The Columbia University Department of Biomedical Informatics is among the oldest in the nation. Its goals are to discover new

    information methods, to augment the biomedical knowledge base, and to improve the health of the population. DBMIs 30 faculty

    members and 60 students work in a highly collaborative environment, applying informatics from the atomic level to global

    populations. Areas of application include:

    CLINICAL CARE. Design clinical information systems and mine the electronic health record.

    BIOLOGY. Includes systems biology, structural biology, and virology, on studies in partnership with the Center forComputational Biology and Bioinformatics.

    PUBLIC HEALTH. Design systems to promote and protect the health of communities, improve public health systems,and deploy information technology internationally.

    TRANSLATIONAL RESEARCH. Integrate biological and clinical knowledge and facilitate multidisciplinary science.

    Department ofBiomedical Informatics

    Biomedical Informatics Update 2012