BIOLOGICAL SCIENCES 370

ANIMAL PHYSIOLOGY Fall 2015

The word "physiology" written in Chinese consists of three characters. Reading downward they mean life, logic and study. The overall meaning becomes "The study of the logic of life."

REQUIREMENT: Cell Biology (315) is a prerequisite for this course.

REQUIRED TEXT: Books and additional materials are on reserve in the library.

● Animal physiology: From Genes to Organisms, 2nd ed., by Sherwood, Klandorf and Yancey; Thompson Brooks/Cole, 2013.

OPTIONAL TEXTS:

● Cellular physiology of nerve and muscle, 4th ed, by G.G. Matthews; Blackwell, 2003.

INSTRUCTORS:

INSTRUCTOR OFFICE PHONE EMAIL OFFICE HOURS

Dr. R. David Heathcote N411 Lapham 229-6471 rdh@uwm.edu T/Th 9:00-10:00 & by appt.

Dr. Jennifer Gutzman N515 Lapham 229-5408 gutzman@uwm.edu T/R 9:00-10:00 & by appt.

Dr. Jane Witten N409 Lapham 229-4993 jlw@uwm.edu M 1:00-3:00 & by appt.

Dr. Reinhold J. Hutz N511 Lapham 229-5416 rjhutz@uwm.edu T/R 9:30-10:30 & by appt.

LECTURE: 11:00 to 12:15 Tuesday and Thursday; Lapham 250.

COURSE OBJECTIVE: This course is intended for Biological Sciences majors and will provide an overview of an area that is one of the cornerstones of modern biology. Principles and mechanisms of physiology will be stressed, taking examples from single-celled organisms, invertebrates and vertebrates. The laboratory course (Bio Sci 372; Animal Physiology and Neurobiology Laboratory) can be taken at the same time as this class and is closely integrated with it.

LECTURE/EXAM SCHEDULE:

WEEK DATES LECTURER LECTURE TOPICS AND SUGGESTED TEXT READINGS

1

Sept 3

DH

Introduction. Permeability and transport. The fluid mosaic model, membrane permeability. Membrane selectivity and properties used in cell communication. Ch. 2 & 3. Matthews Ch. 2 & 3.

2

8,10

DH

Ions and excitation. Passive electrical properties and the Nernst potential. The contribution of ion gradients, ion channels and active transport to resting membrane potential. Ch. 2 & 3. Matthews Ch. 4 & 5.

3

15,17

DH The action potential and the roles of Na + and K+. Propagation and

transmission of signals. Ch. 3 & 4. Matthews Ch. 6 & 7. 4

22 DH Structure and function of electrical and chemical synapses. Synaptic transmitters, receptors and quantal release. Ch. 4. Matthews Ch 8.

24 EXAM I

5 Sept 29, Oct

1 JG Processing of sensory information by the nervous system. Sensory-

motor integration. Reflexes and fixed action patterns. Ch. 5.

6

6,8

JG

Sensory mechanisms. Ch. 6.

7 13,15 JG Chemical messengers. Neuroendocrine relationships. Hormone structure, synthesis, secretion, and mechanism of action. Hormonal regulation of metabolism, growth, and development. Ch. 7.

8 20

22

JG

EXAM II

Osmoregulation and excretion. Diversity of osmoregulatory mechanisms. Kidney function and its role in water and electrolyte balance. Ch. 12 & 13.

9

27,29

JW

Introduction to muscle physiology. Cellular and molecular components of skeletal muscle, excitation-contraction coupling, grading of tension, fiber types and mechanics. Smooth muscle. Ch. 8

10

Nov 3,5

JW

Circulatory systems. Types and components. Evolution of vertebrate hearts and blood circuits. Cardiac muscle and mechanics, structure/function relationships of blood vessels and control of cardiovascular system. Ch. 9.

11

Nov 10,12

JW

Respiratory systems. Gas exchange and transport. Control of respiration. Ch. 11

12

17 EXAM III

19 RH Comparative aspects of nutrient acquisition/feeding strategies. Digestive anatomies; gastrointestinal physiology. Ch. 14.

13

24 26

RH

Digestive enzyme activity. Hormonal regulation of digestion. Absorption at the alimentary canal. Ch. 14. Thanksgiving!

14

Dec. 1,3

RH

Utilization of energy substrates; diets. Introduction to comparative reproductive biology/physiology. Ch. 16. Review Ch. 2, p.85+, Ch. 3,p. 99+.

15

8,10

RH Male reproduction. Female reproductive function. Fertilization, pregnancy, and lactation. Ch. 16. Assisted reproductive technologies (ART)/contraception. Ch. 16. Review

Friday Dec 18

EXAM IV Final Exam: 10:00-12:00 in Lapham 250.

EXAMS: The four exams cover material from lectures and text assignments. For the f irst 3 exams, the questions are at least half “short answer” and problems. The other half will be multiple choice/true- false/matching/fill-in-the-blank, etc. The final will be primarily short-answer essay format. Attendance is required on exam days. We curve the scores for each exam. None of the exams is comprehensive. HOMEWORK: There will be one or two problems or short writing assignments each week, but these will not be graded. They are to assist you in reviewing for your exams. CELL PHONE POLICY: Cell phones should be turned off before class. Check messages after class and absolutely no texting. PLAGIARISM POLICY: Students are responsible for the honest completion and representation of their work and for refraining from giving or receiving unauthorized aid on quizzes, exams, or assignments. At the very least, cheating will result in a grade of zero on the exam, quiz, or assignment involved. In addition, any such instance of academic misconduct will be automatically reported to University authorities and could result in more serious consequences, including a grade of F for the course and/or academic suspension. The following website provides further details regarding University policies and procedures on exams, incomplete grades, religious holidays, discriminatory conduct, student misconduct, grade appeals, and students with disabilities http://www.uwm.edu/Dept/SecU/SyllabusLinks.pdf. FINAL GRADE:

Exam 1 25%

Exam 2 25%

Exam 3 25%

Exam 4 25%

PARTICIPATION BY STUDENTS WITH DISABILITIES: If you need special accommodations in order to meet any of the requirements of this course, please notify the instructors at the start of the semester or at the time those accommodations become necessary.

CREDIT-HOUR POLICY REGARDING TIME ALLOCATION: Students should spend at least three (3) hours per credit per week outside of class studying and reading so as to learn the basic course material. This amounts to at least nine (9) hours outside of class plus three (3) hours in class, for a total of 12 hours per week.

LEARNING OBJECTIVES: Upon successful completion of this course, the student will be able to:

1. Describe and apply biological information and concepts to societal and ethical questions related to biology.

2. Apply the scientific method to questions, critically evaluate experimental design, and interpret numerical and graphical data used in professional research (for example, as published in peer-reviewed journals).

3. Investigate scientific questions using diverse field and laboratory skills, including use of biological instrumentation and appropriate computer software.

4. Retrieve and process scientific information from library catalogs, literature search engines and computer databases.

5. Synthesize, integrate and effectively communicate scientific information both orally and in writing. 6. Demonstrate an understanding of evolution, ecology and environmental biology, cell biology,

physiology and genetic regulation of cellular function.

NOTE: Last dates to drop: 9/29/2015 without “W”; 10/23/2015 with “W”.