BioDisrupt 2019: Amyris Overview€¦ · of the world’s leading personal care and beauty brands • Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North

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BioDisrupt 2019: Amyris OverviewMay 16, 2019

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Cautionary Notes

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Cautionary Notes

FORWARD-LOOKING STATEMENTS

This presentation and oral statements accompanying this presentation contain forward-looking statements, andany statements other than statements of historical fact could be deemed to be forward-looking statements. Theseforward-looking statements include, among other things, statements regarding future events, such as expectedrevenue, gross margin and production volume in 2019, including related growth rates, the anticipateddevelopment, scaling and commercialization of Amyris’s product pipeline and introduction of new products,including HMOs and cannabinoid ingredients, expected growth of Amyris’s Clean Beauty business, the anticipatedsize of the global beauty and personal care market, including categories thereof, as well as Amyris’s entry intocertain of such market categories, including the timing thereof, and expectations regarding Amyris’s financial andoperational results and ability to achieve its business plan in 2019 and beyond. These statements are based onmanagement’s current expectations and actual results and future events may differ materially due to risks anduncertainties, including risks related to Amyris’s liquidity and ability to fund operating and capital expenses, risksrelated to potential delays or failures in development, production and commercialization of products, risks relatedto Amyris's reliance on third parties, and other risks detailed from time to time in filings Amyris makes with theSecurities and Exchange Commission, including Annual Reports on Form 10-K, Quarterly Reports on Form 10-Qand Current Reports on Form 8-K. Amyris disclaims any obligation to update information contained in theseforward-looking statements, whether as a result of new information, future events, or otherwise.

Copyright © 2019 Amyris, Inc. All rights reserved

© 2018 Amyris, Inc. All rights reserved. Confidential & proprietary.

BioDisrupt Conference Agenda – May 16, 2019

9:30am Amyris Main Presentation

10:25am Clean Beauty Movement

11:20am Amyris Technology Roadmap & Product Pipeline

11:50am Lunch Break

Note: Your lunch location is designated on the back of your nametag

12:50pm Chinese Market and Consumers

1:20pm Cannabinoid: The Future of Pain Management, Anxiety, and Better Sleep for All

1:55pm Amyris Closing

2:00pm R&D Tours and Product & Sample Tent – Group A

3:00pm R&D Tours and Product & Sample Tent – Group B

Note: Your tour number is designated on the back of your nametag

4:00pm Gift Bags & Conclusion

3Copyright © 2019 Amyris, Inc. All rights reserved

4Copyright © 2019 Amyris, Inc. All rights reserved4

• The leading pipeline in our

industry:

� Cannabinoids

� Vitamins

� HMOs

• Leadership in

NoCompromise™ natural

products

• Proven technology platform

• Market leader in F&F Ingredients,

Clean Skin Care & Zero Calorie

Natural Sweetener

FERMENTATION

MAKES NATURAL

SUSTAINABLE

Copyright © 2019 Amyris, Inc. All rights reserved 5

From Idea To Industrial-Scale, Making Natural Sustainable

1 Engineer microbial factories

Emeryville, CA, USA

(near San Francisco)

2Produce ingredients using our industrial fermentation technology

Brotas, Brazil

CMOs

3Commercialize through collaboration partners and direct to consumer

Formulate and sell own products



Sources: Leffingwell & Associates article on 2013-2017 Flavor & Fragrance industry leaders.

Estimates are as of Aug 2018. Also published on July ‘18 edition of Perfurmer & Flavorist

** Results for Sensient Flavors & Fragrances excludes all non F&F items

Note - Using Mane's internal actual average exchange rate they reported the U.S. dollar equilalent as USD $1,306.9 million for 2017 and as USD $1,172 million in 2016 and as USD $1,051 million in 2015

Note - We have restated Takasago's sales figures for 2013-2017 to eliminate certain revenue items such as non F&F fine chemicals such as pharmaceutical intermediates as well as real estate revenues.

(1) Market Share is based on U.S. dollar values

(3) Accounting Period of July 1 to June 30

(4) Accounting Period of April 1 to March 31

(5)Accounting Period of Oct. 1 to Sept, 30; Net sales given are Company consolidated sales, See T.Hasegawa Co., Ltd.

(6) Accounting Period of Sept. 1 to August 31 until year 2000

(7) ** See also Note (6). F&F figures in the tables for 2000-2013 for Sensient Flavors &Fragrances

Amyris partners with the leading companies in the industry

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Company Rank Est. 2017 Sales USD$ Market Share

1 Givaudan $5,132.80 19.50%

2 Firmenich $3,668.40 (est) 13.9% (est)

3 IFF $3,398.70 12.90%

4 Symrise $2,672.60 10.20%

5 Mane SA $1,306.10 5.00%

6 Frutarom $1,271.40 4.80%

7 Takasago $1,185.40 4.50%

8 Sensient Flavors $618.80 2.40%

9 Robertet SA $570.00 2.20%

10 T. Hasegawa $428.10 1.63%

0

5

10

15

20

25

30

35

40

45

Product 1Product 1Product 1Product 1 Product 2Product 2Product 2Product 2 Product 3Product 3Product 3Product 3 Product 4Product 4Product 4Product 4 Product 5Product 5Product 5Product 5

Mo

nth

sM

onth

sM

onth

sM

onth

s

From first strain to first pilot run

Lower average product

development cost.

90%

Bigger pipeline,

powered by 20%

increase in headcount

500%

Accelerating Disruption

Lower average time

to market.

80%

2012 2019


Molecule Profile From Launch

Source: consumption per value share reports and/or distributor data 9 Copyright © 2019 Amyris, Inc. All rights reserved

Molecule 2

CAGR : 56%

Molecule 1

CAGR : 85%

Note: 2018 Actual vs.2019 Plan Volume

Our Platform Is Delivering

Farnesene Derived Fragrances ’18- ‘19 Growth

Molecule 1 214%

Molecule 2 scaling up in 2019

Farnesene Derivatives ‘18-’19 Growth

Molecule 1 129%

Molecule 2 301%

Molecule 3 163%

Fermentation Molecules ‘18-’19 Growth

Molecule 1 175%



Molecule 4 Flat

Molecule 5 2000%

Molecule 6 422%

Molecule 7 5800%

Molecule 8 67%

Branded Product Sales

+277%

Ingredient Sales

+61%

2016-2019 REVENUE CAGR

Copyright © 2019 Amyris, Inc. All rights reserved10

Advantaged Portfolio Delivers Strong Growth & Expanding Profitability

2018 20192017

* Adjusted for loss making product sales on contracts and one time revenues

Gross Margin % 49% 52% 55%- 65%

11 Copyright © 2019 Amyris, Inc. All rights reserved

Product

License/Royalties/Collab

OUR BIOSSANCE

BRAND IS

NO COMPROMISE

BEAUTY™

In the U.S., the standards for ingredients allowed in beauty products

are shockingly low—with only 11 banned ingredients.

At Biossance, we draw on our rich history of science and

sustainability to create skincare products that are good for you and

good for the planet.

We formulate with a No Compromise™ approach, setting the bar

higher for both safety and performance.

12 Copyright © 2019 Amyris, Inc. All rights reserved

Biossance Key Growth Indicators (Jan 2017-April 2019)

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Fastest growing Clean Skincare brand in North America.

Powered by Squalane.


2012 2013 2014 2015 2016 2017 2018 2019

3000+ Brands


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Source: Aprinnova Distributor Data

Neossance™ Squalane Growth

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Global Skincare market breakdown (2017, $B) Skincare market distribution channels (2017, $B)

1 – Euromonitor 2017


Beauty & Personal Care Market

Beauty & personal care global market sizes by HPC category (2017, $B)

© 2019 Amyris, Inc. All rights reserved.

Amyris Sweetener Is What Consumers Want

• Diabetes and obesity is rising

• Second-rate taste offerings no longer cut it

• Millennials are demanding pure and natural

• Amyris has the best tasting, most sustainable and purest natural sweetener




Brazil LaunchFall 2019

US LaunchEnd of 2019

Upcoming purecane™ Launches

© 2019 Amyris, Inc. All rights reserved.

• Amyris is the known leader in successfully serving high-growth global markets with fermentation derived, naturally-sourced, sustainable ingredients

• Entering cannabinoids market with proven platform and ability to develop, scale and commercialize ingredientso Executed $300 million development, licensing and commercialization agreement with

additional long-term royalty stream.

• In partnership with DSM, Amyris is moving quickly toward the commercialization of its first Human Milk Oligosaccharide (HMO) molecule, which is in the family of sugars from mother's milk. At the pace we’re moving, we'll have more than one to commercialize.

Product Pipeline – Cannabinoids, Vitamins, and HMO’s for Human Health

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Source: NY TimesConcept and diagram by Paul Sahre. Photo illustration by Jamie Chung. Prop styling by Anna Surbatovich.

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Can CBD Really Do All That?

Promotes Recovery from

Opioid Addiction

Speeds Recovery From Workouts

Lowers Blood Sugar

Lessens Arthritis Pain

Prevents Anxiety

Calms Dogs

Relieves Menstrual Cramps

Helps You Sleep

Slows Alzheimer's Dementia

Curbs Anger

Reverses Depression

Slows Parkinson’s

Treats Crohn’s Disease

Cures Cancer

Stops EpilepsyHeals Brain InjuryHeals PTSD

Halts Psychosis

CBDs For Pain Management, Not Opioids

21Source: US Department of Health and Human Services

Make good.No compromise.

• Our ingredients are inside over $7B of consumer retail purchases

• You’ll find our ingredients in over 3,000 of the world’s leading personal care and beauty brands

• Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North America

• We have the leading product into the natural Sweetener market. We want to replace sugar & are committed to a healthier planet! We want to help reduce risk of Diabetes and Obesity….

• Most profitable product portfolio in the industry

Good for People

Good for the Planet

Good for Business

™


Amyris Awards Won Since BioDisrupt 2018

Product Won:Biossance Squalane

+ Mineral SPF 45

Product Won:Biossance Squalane

+ Peptide Eye Gel

Product Won:Biossance Squalane + Tea Tree Cleansing Gel

Product Won:Biossance Squalane +

Glycolic Renewal Facial

Product Won:Biossance Squalane + Tea Tree Balancing Oil

Category Won:Best Manufacturing &

Processing Technology



Documents

BioDisrupt 2019: Amyris Overview€¦ · of the world’s leading personal care and beauty brands • Our Biossance Skin Care Brand is the fastest growing Skin Care Brand in North