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Submitted byPriyanka Bhalla Sec- O 5028
Carbohydrates
Lipids
Proteins
Dietary lipids in mouth
Retain association to form micelles in lumen
Enter enterocytes through diffusion
Stomach (chyme)
Forms free fatty acids by hydrolysis by lipases
Transported to ER for conversion of micelles into triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
No digestion takes place here cause SALIVA contains NO LIPASEDietary lipids in mouth Retain association to form micelles in lumen Enter enterocytes through diffusion
Stomach (chyme)
Forms free fatty acids by hydrolysis by lipases
Transported to ER for conversion of micelles into triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
Dietary lipids in mouth
Retain association to form micelles in lumen
Enter enterocytes through diffusion
Stomach (chyme)
Transported to ER Forms free fatty the food is partly digested In stomach for conversion of acids by hydrolysis a semi fluid mass called to form micelles into by lipases CHYME. But still full triglycerides digestion doesn t take place cause stomach lacks fat-emulsifying agent. Small lipid droplets -emulsification by bile salts Move to Golgi complex to combine with cholesterol & apoprotiens
Duodenum (large lipid aggregates)
Dietary lipids in mouth
Retain association to form micelles in lumen
Enter enterocytes through diffusion
Stomach (chyme)
Gastric juice in duodenum contains gastric lipases which converts some Transported to ER fats into monoglycerides and fatty Forms free fatty for conversion of acids acids by hydrolysis micelles into by lipases triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets -emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
Dietary lipids in mouth
Large lipid aggregates dissociate into small lipid droplets due to Retain association EMULSIFICATION by BILE SALTS to form micelles in which are obtained by Cholesterol lumen Metabolism.
Enter enterocytes through diffusion
Stomach (chyme)
Forms free fatty acids by hydrolysis by lipases
Transported to ER for conversion of micelles into triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets -emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
Dietary lipids in mouth
Retain association to form micelles in lumen
Enter enterocytes through diffusion
Stomach (chyme)
Forms free fatty acids by hydrolysis by lipases
Transported to ER for conversion of micelles into triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
Dietary lipids in mouth
Retain association to form micelles in lumen
Enter enterocytes through diffusion
Stomach (chyme)
Forms free fatty acids by hydrolysis by lipases
Transported to ER for conversion of micelles into triglycerides
Move to Golgi Small lipid droplets complex to combine Duodenum (large -emulsification by bile salts lipid aggregates) Fatty acids retain association with with cholesterol & bile salts and complex with other lipid molecules to apoprotiens form micelles of 4-8 nm diameter
Lipids are broken down by pancreatic lipase and bile, and then diffuse into the Retain association Dietary lipids in ENTEROCYTES. Smaller lipids arein to form micelles mouth lumen transported into intestinal capillaries, while larger lipids are processed by the Golgi and smooth endoplasmic reticulum into lipoprotein chylomicra and Forms free fatty Stomach (chyme)exocytozed into lacteals. acids by hydrolysis by lipases
Enter enterocytes through diffusion
Transported to ER for conversion of micelles into triglycerides
Duodenum (large lipid aggregates)
Small lipid droplets -emulsification by bile salts
Move to Golgi complex to combine with cholesterol & apoprotiens
Steps of Absorption Of LIPIDS.
Move to Golgi complex for conversion of micelles to triglycerides for diff. functions
Finally to ORGANS
Form chylomicrons
Proceed to BLOOD stream
Fuse with cell membrane & released exocytosis
Enter lymphatic system
From the micelles Move to Golgi complex fatty acids , Glycerides,sterols and fat for conversion of Soluble to micellesvitamins reFinally to ORGANS Synthesize diff. triglycerides for in ER to get converted into very small functions Fat molecules called CHYLOMICRONS
Form chylomicrons
Proceed to BLOOD stream
Fuse with cell membrane & released exocytosis
Enter lymphatic system
Gal bladder
Gal bladder
1. Bile salts emulsify Dietary fats in small Interstine, forming Mixed micelles.
Gal bladder
2. Intestinal lipases Degrade triacylglycerols.
Gal bladder
Small intestine
3. Fatty acid and other Breakdown products are taken up By the intestinal mucosa & converted into triglycerols
Gal bladder
Small intestine
Intestinal mucosa Apo C-II 4. Triacylglycerols are Incorporated, with cholesterol & apolipoprotiens into chylomicrons
Gal bladder
Small intestine
Intestinal mucosa Apo C-II
5. Chylomicrons move Through the lymphatic System & blood stream To tissues. Chylomicron
Gal bladder
Small intestine
Lipoprotein lipase 6. Lipoprotein lipase, Activated by apoC-II in The capillary, converts Triacylglycerols to fatty Acids & glycerol Chylomicron
Intestinal mucosa Apo C-II
Gal bladder
7. fatty acids enter cells Small intestine Lipoprotein lipase
Intestinal mucosa Apo C-II Chylomicron
8. Fatty acids are oxidized as Fuel or reesterified for storage. Gal bladder Myocytes & adipocyte
Small intestine
Lipoprotein lipase
Intestinal mucosa Apo C-II Chylomicron