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BED SIDE TEACHING 2 HERPES ZOSTER

Bed Side Teaching 2(1)

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BST Herpes Zooster

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BED SIDE TEACHING 2

BED SIDE TEACHING 2HERPES ZOSTERGROUP MEMBERSA. Ayu FaradibaA. Intan P PutriJefman E Marzuki H YMuh. Firmansyah KamalPriska ParamitaWahyunita IlhamPATIENTS IDENTITYName: Mr. TGender: MaleAge: 23 y.oMarital Status: SingleReligion: ChristianAddress: Irian JayaOccupation: ArmyRegistered: 23th March 2013

HISTORY TAKINGAnamnesis: Autoanamnesis

Chief complaint: - Multiple tiny blister with pain below the lower lip

HISTORY TAKINGFever (+), pain on lesion (+), nausea (-), vomiting (-), headache(-), dizziness (-), chest pain (-). During the appearance of disease, urination and defecation within normal limit.PRESENT HISTORY- Vesicle appeared 2 days ago, with pain. Location below the lower lip.- 4 days ago, went to hospital with diagnosed suspect malaria

Past history:history of malaria for 4 days ago.Allergic history:No Allergic historyFamily history:No family member that have similar disease with patient

PRESENT STATUSGeneral condition:Moderately illConsciousness:Compos mentis (Alert)Vital sign:BP: 130/80 mmHgPulse: 62x/minuteRespiratory rate:24x/minuteTemperature: 36,5 0 CHead ExaminationJaundice(-)Pale (-)cyanosis (-)Cor/ Pulmo- within normal limit/within normal limitThoraxVesiculer, Rh (-/-) Wh(-/-)AbdomenPeristaltic (+)ExtremitiesEdema (-)LocalizationUniversal Dermatology Status-Location: regio perioral-Efflorescence: multiple vesicles, erythematous, and scaly

Diagnosis: - Herpes Zoster

Treatment: DexamethasoneGentamycin 80 mg/12 h/i.vKenalog oral base+acyclovirNeurodex 3 x 1Tramadol 2 x 1Acyclovir 5 x 400 mg

RESUME23 y.o male, brought to dermatovenereology department on March 26th 2013 with chief complain of multiple vesicles appear below the lower lip since 2 days ago. First, the lesion appearead only on the right side, and lately spread on both areas. Pain (+), fever (+) since 4 days ago. He lately suspected got malaria. He has treated with antipyretic drugs, antibiotics, and antiviral drugs.Vital sign: BP: 130/80 mmHg, Pulse: 62x/minute, Respiratory rate: 24x/minute, Temperature: 36,5 CDermatovenereology :-Location:perioral regionEfflorescence:multiple vesicle, erythematous, and scaly.

DIAGNOSISHerpes ZoosterDIFFERENTIAL DIAGNOSISHerpes simplex, impetigo, smallpox, atopic dermatitis, poison ivy, atypical measles

MANAGEMENTDexamethasoneGentamycin 80 mg/12 h/i.vKenalog oral base+acyclovirNeurodex 3 x 1Tramadol 2 x 1Acyclovir 5 x 400 mgPROGNOSIS:Bonam

HERPES ZOSTERDefinition :The disease is caused by the varicella zoster virus that attacks the skin and mucosa. This is a reactivation of the virus infection that occurs after primary infection.

DiscussionEtiologyVaricella zoster virusThe incubation period is 7-12 daysActive period of 1 weekResolution period 1-2 weeks

Patophysiology (Cont...)Cont.... (1)

Cont... (2)Clinical ManifestationProdromal pain typically is described as muscle or toothachelike in origin but may simulate headache, iritis, pleurisy, brachial neuritis, cardiac pain, appendicitis or other intra-abdominal disease, or sciatica. This simulation can result in incorrect tentative diagnoses; however, the dermatomal distribution usually helps clarify the diagnosis.Differential DiagnosisHerpes simplexImpetigoSmallpoxAtopic dermatitisPoison ivyAtypical measlesLab TestTzanck Smear for diagnose acute infectionViral culture 3-14 days for viral growth, sensitivitation 30-70%, spesific 100%Antigen IgM detection Serologic test ELISA, commonlyPCR DNA VZV detection exc. CSSTreatment Oral therapy :Analgetic (symptomatic)AntibioticAntiviralAcyclovir 5 x 800 mg/day (7 days)Valacyclovir 3 x 1000 mg/day (1 dayTricyclic antidepresan- Amytriptilin 75 mg/dayTopical therapy :MBS talc -> prevent vesicle rupture.Open compretion-> if theres erotion.Antibiotic cream -> if theres ulkus.