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“It’s truly exhilarating tobe recognized for yourhard work. This prizewill motivate younggenerations of scientistsand encourage newdiscoveries.“

Submission

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August 1

imagination at work

For the purpose of this prize, molecular biology isdefined as “that part of biology which attempts tointerpret biological events in terms of the physico-chemical properties of molecules in a cell”.

(McGraw-Hill Dictionary of Scientific andTechnical Terms, 4th Edition).

GE Healthcare Bio-Sciences AB, a GeneralElectric Company.Björkgatan 30, 751 84 Uppsala, Sweden.© 2009 General Electric Company– All rights reserved.

The GE & Science Prize for Young Life Scientists.

Rewarding brilliance since 1995.

Imagine standing on the podium at the Grand Hotel in Stockholm, making youracceptance speech. Imagine joining the ranks of those published in Science magazineand having your essay on your work in molecular biology read by your peers aroundthe world. Imagine taking part in a seminar with the other Prize winners and NobelPrize laureates and discussing your work with leaders in the field. Imagine what youcould do with the US$25,000 prize money. Imagine this brilliant start to your careerand where it could lead you. Now stop imagining, and make it a reality.

Dr. Christine Jacobs-Wagner did just that. In 1997, she entered in the GE & SciencePrize for Young Life Scientists and won the grand prize. So why not you? If you are oneof those who were awarded a Ph.D in 2008, then submit your 1000-word essay byAugust 1, 2009. Your brilliant idea could well be on its way to building a better reality,for you and for those around you.

All the information you need awaits you at: www.gelifesciences.com/science

Dr. Christine Jacobs-Wagner

Grand Prize winner 1997

GE Healthcare

Coordinate your application focus.Achieve greater operational efficiency.GE Healthcare is focused on helping you develop efficient biopharmaceutical

process flows and eliminating wasteful practices, taking your value stream to

new frontiers. Through our wide range of technology platforms and services,

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scale, GE Healthcare can connect you to the power of operational excellence.

Learn more about operational excellence at: www.gelifesciences.com/opex

GE Healthcare Bio-Sciences AB, a General Electric CompanyBjörkgatan 30, 751 84 Uppsala, Sweden© 2008 General Electric Company – All rights reserved.

GE04-09. First printetd 09/2008.

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What’s up (or down) with your protein?SILAC can tell you, even in your stem cells.

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High Fidelity (HF) Restriction Enzymes - the next generation•

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LIFE SCIENCE TECHNOLOGIESAAAS/Science Business Office

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizationsare featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of anyproducts or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

1217www.sciencemag.org/products SCIENCE VOL 324 29 MAY 2009

Nitrogen/Sulfur/Chlorine AnalyzerThe Titan 4000 NSX analyzer for total nitrogen, sulfur, and chlorine analysis offers users in the refineryand petrochemical markets superior sample introduction and oxidative combustion performance. Itsinnovative detectors enable fast analysis speed with accuracy and reliability of results. Its range cov-ers concentrations from low parts per billion to high parts per million. The incorporation of a powerfulcombustion method allows the analyzer to cater to a wide range of applications in refinery and chemicalsamples, including naphtha, aromatics, automotive fuels, biodiesel fuels, and LPG samples. The ana-lyzer can process total nitrogen and total sulfur samples in two minutes and total chlorine samples inunder four minutes.

ThermoFisher ScientificFor information +44-1606-548779

www.thermo.com/titan4000

DNA, RNA, and Protein IsolationThe illustra triplePrep kit is for rapid, simultaneous isolation of ge-nomic DNA, RNA, and total denatured protein from a single undi-vided sample in less than one hour. The kit is a combination of twospin columns and six buffers optimized for use with mammalian cellculture or animal tissue. High quality and yield DNA, RNA, and pro-tein can be successfully isolated from a range of tissue types, suchas liver, kidney, spleen, brain, lung, and intestine, and the cell linesHeLa, NIH-3T3, CHO-K1, and HEK-293. Tissue amounts ranging from1 to 20 mg and cell amounts ranging from 0.3 million to 5 millioncells can be used for each preparation. Direct correlations of dataderived from genomic DNA, RNA, and protein can be drawn withconfidence because the data are obtained from the same undividedstarting sample.GE HealthcareFor information 262-501-0777www.gelifesciences.com

Dispensing DeviceThe sciSwifter is a device for high-precision dispensing in 96-well,384-well, and 1,536-well microplates. A drop-on-demand dispenser,it can dispense up to 16 different substances in parallel into vari-ous multiwell formats. The dispensing range is 100 pl to 100 µl withdead volumes close to zero. Each nozzle has online-drop-control andoptical volume determination. The dispenser includes integratedtouch-screen controls, a robotics shuttle, and external software forintegration into automated robotics platforms. Its disposable pentechnology enables preparation, storage, sonication, and dispens-ing of reagents to be performed in one integrated device. Substanc-es can be stored directly in the dispensing pen, which serves as aclosed container, eliminating the need for heat seals and ensuringsample integrity.Scienion and Matrical BioscienceFor information +49-(0)30-6392-1700 and 509-343-6225www.scienion.com and www.matrical.com

Positive Displacement PipetteThe Pos-D is a positive-displacement pipette with ergonomic fea-tures. Nonaqueous solutions that are viscous, dense, or high invapor pressure are difficult to aspirate correctly with regular air-dis-placement pipettes. The Pos-D overcomes this problem by providingthe pressure equalization needed to handle such solutions within

the pipette tip. For example, a volatile liquid that would otherwiseevaporate and force some of the sample out of the tip remains intactwith the Pos-D because of the pressure equalization. The Pos-D’slarge handle fits comfortably in the hand. An ergonomic finger-hookeliminates the need to grip the pipette firmly. The volume controlsetting faces the user.Mettler ToledoFor information 800-472-4646www.mt.com/RAININ-Pipettes

Hepatocyte IsolationThe Hepatocyte Isolation System provides reliable, convenient, andconsistent hepatocyte cell isolation. The kit contains an optimizedcombination of enzymes to minimize lot-to-lot variation and improvethe quality of the isolated hepatocytes. Each kit includes single-useenzyme vials, balanced salt solution, buffer, culture media, and aprotocol for five adult rat liver perfusions. A modified protocol formouse applications is also available.Worthington Biochemical Corp.For information 800-445-9603www.worthington-biochem.com

Reactor MasterThe Reactor Master is for automating jacketed reactor systems anddata logging without the need for any PC software. Designed for usewith synthesis equipment in chemical laboratories, the system canautomate circulators or chillers, stirrers, thermocouples, and resis-tance temperature detectors from virtually any manufacturer via aneasy-to-use control knob. Data can be viewed in real-time and ex-ported for offline analysis. The Reactor Master Basic is controlledusing a multifunction knob that allows set points, ramps, or sophis-ticated profiles for temperature and stirring speed. Data are contin-ually saved as a CSV file that can be exported with a USB stick. TheReactor Master Pro features closed loop control of the circulator fora uniform reaction temperature. A software upgrade enables graphsto be generated with the click of a button. Both models are compat-ible with a wide range of thermoregulators, temperature sensors,overhead stirrers, pH meters, and turbidity systems.SyrrisFor information 516-312-3028www.syrris.com

New Products

CALL FOR PAPERS

IntegratingMedicine and Science

Review the information for authors athttp://sciencemag.org/marketing/stm/papers.dtl

www.ScienceTranslationalMedicine.org

» Elias A. Zerhouni,M.D.Chief Scientific AdviserSenior Fellow,Global Health Program,Bill &Melinda Gates FoundationFormer Director,National Institutes of Health

» Katrina L. Kelner, Ph.D.EditorAmerican Association forthe Advancement of Science

Submit your research atwww.submit2scitranslmed.org

Formore information, contactEditor Katrina Kelner, Ph.D. atscitranslmededitors@aaas.org

Advisory BoardMembers

Kenneth R. Chien,M.D., Ph.D.Director, Cardiovascular Research Center,Massachusetts General Hospital,Harvard StemCell Institute,HarvardMedical School

Harry C. Dietz, M.D.Professor, Institute of GeneticMedicine,Johns Hopkins HospitalInvestigator, Howard HughesMedical Institute,Johns Hopkins University School ofMedicine

Jeffrey I. Gordon,M.D.Director, Center for Genome Sciences,Washington University in St. Louis,School ofMedicine

Philip Greenland,M.D.Senior Associate Dean, Clinical and TranslationalResearch, Feinberg School ofMedicineDirector,Northwestern University, Clinical andTranslational Sciences InstituteFormer Editor, Archives of Internal Medicine

Joseph B.Martin, M.D.Professor,Neurobiology and Co-Chair,Governance,NeuroDiscovery Center, HarvardMedical SchoolFormer Dean,HarvardMedical School

Elizabeth G. Nabel, M.D.Chief and Principal Investigator,Nabel Lab,Cardiovascular Branch, Vascular Biology SectionDirector,National Heart, Lung, and Blood Institute,National Institutes of Health

ScienceTranslationalMedicine, to be publishedonline weekly beginning in the fourth quarter2009, focuses on the conversion of basicbiomedical research into practical applications,thus bridging the research-to-application gap.

The editors ofScienceTranslationalMedicineare acceptingmanuscripts for review in thefollowing areas:cancer, cardiovascular disease, metabolism/diabetes/obesity, neuroscience/neurology/psychiatry, immunology/vaccines, infectiousdiseases, policy, behavior, bioengineering,physics, chemical genomics/drug discovery,imaging, applied physical sciences, medicalnanotechnology, drug delivery, biomarkers,gene therapy/regenerativemedicine, toxicologyand pharmacokinetics, datamining, cell culture,animal, and human studies, medical informatics,and other interdisciplinary approaches tomedicine.

ScienceTranslationalMedicine!

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2008 © Invitrogen Corporation. All rights reserved. These products may be covered by one or more Limited Use Label Licenses (see the Invitrogen catalog or our website, www.invitrogen.com).

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