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Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

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Page 1: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 2: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 3: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 4: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

GOLD COAST - Anterior STEMI

Page 5: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Clinic Visit- 6 weeks after ACS

Page 6: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Atrial fibrillation + ACS

5 FOLD

Page 7: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

What ’ s I mpor t ant ?

Page 8: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Page 9: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

••

Page 10: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 11: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

t i me…………

Page 12: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

IMPROVE RISK

Page 13: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

TRIPLE versus DOUBLE THERAPY –

WOEST Trial

Page 14: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 15: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Unanswer ed Q’ s

Page 16: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Page 17: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

12 months

6 months

4 weeks

0

OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in AF (dabigatran 110 mg BID, rivaroxaban 15 mg OD oapixaban 2.5 mg BID) *Dual therapy with oral anticoagulation and clopidogrel may be considered in selected patients; **ASA as an alternative to

2014 European guidance recommends a step-wise approach to individualize care

Time from PCI/ACS

Lifelong

Page 18: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

12 months

6 months

4 weeks

0

OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in AF (dabigatran 110 mg BID, rivaroxaban 15 mg OD oapixaban 2.5 mg BID) *Dual therapy with oral anticoagulation and clopidogrel may be considered in selected patients; **ASA as an alternative to

2014 European guidance recommends a step-wise approach to individualize care

Time from PCI/ACS

Lifelong

Page 19: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 20: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 21: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 22: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Dabigatran 110m

Page 23: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Optimal duration of DAPTafter ACS?

Page 24: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

– –

Page 25: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 26: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 27: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in
Page 28: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

Conclusion

Page 29: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in

THANK YOU

Page 30: Auckland Heart Group | Cardiology Services | Paediatric ... docs/IHD Balancin… · OAC, oral coagulation: either warfarin (INR: 2.0–2.5) or non-VKA OAC at lower tested dose in