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SCIENTIFIC PROGRAM DAY 1 – Wednesday, Sept 19 th 15:30 Start checkin (coffee and sandwich will be served) 16:50 Welcome speech 17:00 Ulf Hedin, Karolisnka Institute “Unstable atherosclerosis: from patient to molecule to patient” 17:40 Lukas Tomas, Lund University “CD4+CD28null T cells in the prediction of incident coronary” 18:00 Katarina Wadén, Karolinska Institute “Correlation of clinical risk scores for stroke with carotid plaque gene expression profiles in atherosclerotic patients” 18:20 Elmir Omerovic, University of Gothenburg “TBA” 19:30 Dinner 21:00 Scientific Bar DAY 2 – Thursday, Sept 20 th 08:00 Breakfast 09:00 Myriam Aouadi, Karolinska Institute “Macrophage contribution to Insulin Resistance independently of Inflammation” 09:40 Gustavo Luis Tripodi, University of Sao Paulo “Inflammasome activation in human macrophages induced by a LDL () mimetic peptide” 10:00 Urszula Rykaczewska, Karolinska Institute “FOXC1 is a major transcription factor in atherosclerotic plaques influencing SMC activation” 10:20 Coffee break 10:50 Anja Meissner, Lund University “Sphingosine1phosphate signaling in cardiovascular disease” 11:30 Margherita Botta, University of Gothenburg “Adipokines affect pcsk9 expression: in vitro and in vivo evidence” 12:00 Lunch 13:00 Katariina Öörni, Wihuri Research Institute, Finland “The susceptibility of LDL particles to aggregate is associated with cardiovascular deaths“ 13:50 Divya Thiagarajan, Karolinska Institute “IgG1 antiPC reduces CVD risk in SLE patients by efficiently clearing apoptotic cells” 14:10 Message from the Sponsors 14:40 Break 17:30 Poster Session 19:30 Dinner 21:00 Scientific Bar Ystad Saltsjöbad 19 – 21 September Atheroma Club 2018 Molecular Mechanisms in Cardiovascular Disease

Atheroma2018 final program- program-.pdfficBar!! SCIENTIFIC(PROGRAM((DAY3–(Friday,(Sept(21st((08:00! Breakfast! 09:00( Emma(Börgeson,(University(of(Gothenburg(( “Inflammatory(resolution(in

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SCIENTIFIC  PROGRAM  

DAY  1  –  Wednesday,  Sept  19th    15:30   Start  check-­‐in  (coffee  and  sandwich  will  be  served)  16:50   Welcome  speech  17:00   Ulf  Hedin,  Karolisnka  Institute     “Unstable  atherosclerosis:  from  patient  to  molecule  to  patient”  17:40   Lukas  Tomas,  Lund  University     “CD4+CD28null  T  cells  in  the  prediction  of  incident  coronary”  18:00   Katarina  Wadén,  Karolinska  Institute  

“Correlation  of  clinical  risk  scores  for  stroke  with  carotid  plaque  gene  expression  profiles  in  atherosclerotic  patients”  

18:20   Elmir  Omerovic,  University  of  Gothenburg     “TBA”  19:30   Dinner  21:00   Scientific  Bar    

DAY  2  –  Thursday,  Sept  20th    08:00   Breakfast  09:00   Myriam  Aouadi,  Karolinska  Institute     “Macrophage  contribution  to  Insulin  Resistance  independently  of  Inflammation”  09:40   Gustavo  Luis  Tripodi,  University  of  Sao  Paulo     “Inflammasome  activation  in  human  macrophages  induced  by  a  LDL  (-­‐)  mimetic  peptide”  10:00   Urszula  Rykaczewska,  Karolinska  Institute     “FOXC1  is  a  major  transcription  factor  in  atherosclerotic  plaques  influencing  SMC  activation”  10:20   Coffee  break  

10:50   Anja  Meissner,  Lund  University     “Sphingosine-­‐1-­‐phosphate  signaling  in  cardiovascular  disease”  11:30   Margherita    Botta,  University  of  Gothenburg     “Adipokines  affect  pcsk9  expression:  in  vitro  and  in  vivo  evidence”  12:00   Lunch  13:00   Katariina  Öörni,  Wihuri  Research  Institute,  Finland  

“The  susceptibility  of  LDL  particles  to  aggregate  is  associated  with  cardiovascular  deaths“  

13:50   Divya  Thiagarajan,  Karolinska  Institute     “IgG1  anti-­‐PC  reduces  CVD  risk  in  SLE  patients  by  efficiently  clearing  apoptotic  cells”  

14:10   Message  from  the  Sponsors  14:40   Break  

17:30   Poster  Session  

19:30   Dinner  21:00   Scientific  Bar    

Ystad  Saltsjöbad  -­‐  19  –  21  September  

Atheroma  Club  2018

-­‐  Molecular  Mechanisms  in  Cardiovascular  Disease  -­‐  

 

fic  Bar    

SCIENTIFIC  PROGRAM    DAY  3  –  Friday,  Sept  21st    08:00   Breakfast  09:00   Emma  Börgeson,  University  of  Gothenburg     “Inflammatory  resolution  in  cardiometabolic  disease”  09:40   Shailesh  Kumar  Samal,  Karolinska  Institute  

“Low  IgM  antibodies  levels  against  malondialdehyde  associates  with  all-­‐cause  haemodialysis  mortality  in  patients  undergoing  hemodialysis”  

10:00   Ekaterina  Chernogubova,  Karolinska  Institute  “Genetic  depletion  of  the  long  non-­‐coding  RNA  H19  in  mice  protects  from  elastase-­‐induced  abdominal  aortic  aneurysms”  

10:20   Coffee  break  10:50   Harry  Björkbacka,  Lund  University     “Immunometabolism  in  atherosclerosis”  11:30   Maria  J.  Forteza,  Karolinska  Institute  

“Metabolic  reprogramming  of  the  immune  system  decreases  inflammation  and  atherosclerosis  in  hypercholesterolemic  mice”  

11:50   Concluding  remarks/End  of  the  meeting  12:00   Lunch      

                                 

Organizers:          

Atheroma  Club  2018

-­‐  Molecular  Mechanisms  in  Cardiovascular  Disease  -­‐   Ystad  Saltsjöbad  -­‐  19  –  21  September