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Page 1: Association for Academic Surgery 35th Annual Meeting

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SCIENTIFIC PROGRAM

Association for Academic Surgery

ournal of Surgical Research 100, 233–244 (2001)oi:10.1006/jsre.2001.6264, available online at http://www.idealibrary.com on

35th Annual Meetinguke

Hilton Milwaukee City Center, Milwa

THURSDAY, NOVEMBER 15, 2001

9:00 am–6:00 pm Registration5th Floor Foyer

:30 am–11:30 am President’s WorkshopCrystal Ballroom

“Challenges for Surgical Leaders”Moderator: David H. Berger

“Changes in Surgical Leadership Styles”Bernard M. Jaffe, M.D.

“The Surgical Chair as a Leader in theAcademic Medical Center”Raphael Pollock, M.D., Ph.D.

“Women as Surgical Leaders”Kim Kahng, M.D.

“Barriers for Minorities to SurgicalLeadership”Claude Organ, M.D.

“Alternative Leadership Opportunitiesfor Surgeons”Charles Balch, M.D.

1:30 am Nominating Committee Meeting

2:00 pm–1:00 pm Lunch (not provided)

:00 pm–3:30 pm Plenary SessionCrystal BallroomModerator: David H. Berger, M.D.

1. The Development of a Focused Breast Workshop To Im-prove Clinical Skills of Medical Students. G. T. Ault, M.D.,MSED, M. Sullivan, R.N., M.S., J. R. Chalabian, M.D., and K.Skinner, M.D., Department of Surgery, LAC–USC MedicalCenter, Los Angeles, CA

2. Neutralization of IL-18 Protects Cardiac Function dur-ing Endotoxemia with Minimal Effect on TNF. C. D. Rae-burn, M.D., C. A. Dinarello, M.D., M. A. Zimmerman, M.D.,C. M. Calkins, M.D., X. Meng, M.D., Ph.D., and A. H. Harken,M.D., University of Colorado Health Sciences Center, Denver,

CO

3. TNF-Induced Microvascular Permeability: The Role ofRho GTPase and MAPK Activation. F. E. Nwariaku, M.D.,

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e, Wisconsin, November 15–17, 2001

Z. Liu, M.D., Ph.D., S. L. Duffy, B.S., X. Zhu, M.D., L. Terada,M.D., and R. H. Turnage, M.D., UTSWMC. Dallas, TX

4. The COOH Terminal Domain of TSP-1 Induces VSMC Che-motaxis via ERK and p38. T. S. Lee, M.D., E. T. Olson, B.A.,S. M. Nesselroth, M.D., M. Yamaguchi, M.S., J. Lawler, Ph.D.,B. E. Sumpio, M.D., Ph.D., and V. Gahtan, M.D., Yale UniversitySchool of Medicine, New Haven, CT; and Harvard Medical School–Beth Isreal Deaconess Medical Center, Boston, MA

5. Cyclooxygenase-2 Expression Attenuates Intestinal In-flammation in Experimental Necrotizing Enterocolotis.D. A. Potoka, M.D., E. P. Nadler, M.D., A. Stanford, M.D., P. A.Boyle, LATG, C. Wong, M.S., R. Zamora, Ph.D., J. S. Upper-man, M.D., and H. R. Ford, M.D., Children’s Hospital of Pitts-burgh, Pittsburgh, PA

6. Neutral Endopeptidase Is a Determinant of Severity in aModel of Pancreatitis-Associated Lung Injury. A. M.Lightner, M.D., T. H. Jordan, B.S., C. E. Jaffray, M.D., E. F.Grady, Ph.D., and K. S. Kirkwood, M.D., University of Califor-nia at San Francisco, San Francisco, CA

7. Sensitivity Analysis for 10 Predictive Risk Factors forBariatric Surgery Complications. S. Huerta, M.D., C. Ko,M.D., C. Liu, M.D., and E. H. Livingston, M.D., UCLA, LosAngeles, CA

8. In Esophageal Carcinoma, Altered Trafficking of FasConfers Resistance to Fas Mediated Apoptosis by aWild-Type p53-Independent Mechanism. R. S. Ma-hidhara, M.D., and S. J. Hughes, M.D., University of Pitts-burgh, Pittsburgh, PA

9. Protein Kinase C (PKC) Activation of Intestinal Glu-tamine Transport Is Mediated by Mitogen-Activated Pro-tein Kinases (MAPKs). W. W. Souba, M.D., Sc.D., A. M.Karinch, Ph.D., C. Lin, Ph.D., and M. Pan, M.D., Ph.D., PennState University College of Medicine, Hershey, PA

10. Profound Arginine Deficiency Contributes to Liver In-jury after Hepatic Transplantation. G. P. Yagnik, B.S., Y.Takahashi, M.D., G. Tsoulfas, M.D., S. Chia, M.D., N. Murase,M.D., and D. A. Geller, M.D., University of Pittsburgh School ofMedicine, Pittsburgh, PA

:30 pm–4:00 pmRefreshment Break

Crystal Foyer

0022-4804/01 $35.00Copyright © 2001 by Academic Press

All rights of reproduction in any form reserved.

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3:30 pm–4:00 pm

Authors to Set Up Posters for RegularPoster Presentations

Regency Ballroom

:00 pm–5:15 pm

Committee on EducationCrystal Ballroom

Chairman: Kristin A. Skinner, M.D.“The Changing Face of Surgical Education”

“Surgical Education: No Role for a MinimallyInvasive Approach”Gary L. Dunnington, M.D.Southern Illinois University School ofMedicine, Springfield, IL

“Simulators, Videotrainers, and Virtual Reality: SeeOne, Do One, Teach One”Daniel B. Jones, M.D.University of Texas Southwestern MedicalCenter, Dallas, TX

:30 pm–6:30 pm

Poster Session/Wine & Cheese ReceptionRegency Ballroom

:30 pm–7:15 pm

Cutting Edge Technology Industry-Sponsored SessionOak and Kilbourn Rooms

FRIDAY, NOVEMBER 16, 2001

6:30 am–7:30 am

New Member Breakfast (Invitation Only)Empire Ballroom

:30 am–5:00 pm

Registration/Continental BreakfastCrystal Foyer

:30 am–9:30 am

Parallel Session IWalker RoomCategory: CARDIOTHORACICModerators: Lishan Aklog, M.D.

Marc R. Moon, M.D.

11. Cloning, Tissue Distribution, and Analysis of the MouseSurfactant Protein A Receptor. A. S. Chang, M.D., M. J.Reardon, M.D., D. Strayer, M.D., Ph.D., and F. J. Demayo,Ph.D., Baylor College of Medicine, Houston, TX

12. Improved Perfusion and Function with MyocardialGene Therapy. K. A. Horvath, M.D., C. J. Lu, N. Belkind,J. W. Lomasney, M.D., R. Greene, D. D. Mcpherson, M.D., andD. A. Fullerton, M.D., Northwestern University Medical School,Chicago, IL

13. Gene Transfer of HGF Induces Coronary Angiogenesisand Preserves Myocardial Contractility in Chronic Isch-

234 SCIENTIFI

emia. S. Chatterjee, M.D., A. S. Stewart, M.D., L. T. Bish, H.Sweeney, Ph.D., and T. J. Gardner, M.D., Hospital of the Uni-versity of Pennsylvania, Philadelphia, PA

14. Analysis of Myocardial Collagen Gene Expression andFibrosis in LVAD-Supported Patients. B. A. Bruckner,M.D., S. Stetson, B.S., I. Uray, M.D., L. Thompson, M.D., M.Loebe, M.D., Ph.D., J. Lafuente, M.D., P. Davies, M.D., Ph.D.,H. Taegtmeyer, M.D., Ph.D., G. Noon, M.D., and K. Youker,Ph.D., Baylor College of Medicine, Houston, TX

15. Intramyocardial Levels of Basic Fibroblast GrowthFactor (bFGF)Are Upregulated at 3 and 6 Months in aPorcine Model of Hibernating Myocardium. J. E. Scar-borough, M.D., M. L. Smith, B.S., P. W. Domkowski, M.D.,L. H. Diodato, M.D., B. H. Annex, M.D., P. K. Smith, M.D.,and K. P. Landolfo, M.D., Duke University Medical Center,Durham, NC

16. Novel Cellular Protection Strategy for PulmonaryTransplantation. A. M. Vaida, M.D., C. A. Allen, R. S.Higgins, M.D., and N. M. Cohen, M.D., Ph.D., Medical Col-lege of Virginia of Virginia Commonwealth University, Rich-mond, VA

17. Persistence of Cardioprotection in Chronically HypoxicRabbits Subsequently Exposed to Normoxia: Role ofKATP Channels. C. M. Fitzpatrick, M.D., B. Ostadal, D.S.C.,G. J. Gross, Ph.D., and J. E. Baker, Ph.D., Medical College ofWisconsin, Milwaukee, WI

18. PDGFBB Increases Myocardial Production of VEGF:Shift in VEGF mRNA Splice Variants after Direct In-jection of BFGF, PDGFBB, AND PDGFAB. D. G. Affleck,M.D., D. A. Bull, M.D., S. H. Bailey, M.D., A. Albanil, B.S., R.Connors, B.A., J. C. Stringham, M.D., and S. V. Karwande,M.D., Department of Surgery, University of Utah, Salt LakeCity, UT

7:30 am–9:30 am

Parallel Session IOak RoomCategory: PEDIATRICSModerators: Terry L. Buchmiller-Crair, M.D.

George K. Gittes, M.D.

19. Selective Inhibition of the Epidermal Growth Factor Re-ceptor Impairs Intestinal Adaptation after Small BowelResection. D. P. Obrien, M.D., L. A. Nelson, M.D., J. L. Wil-liams, B.S., C. J. Kemp, B.S., C. R. Erwin, Ph.D., and B. W.Warner, M.D., Division of Pediatrics, Children’s Hospital Med-ical Center, Cincinnati, OH

20. Chronic Hypoxia Attenuates Endothelin-1 InducedIncrease in Fetal Pulmonary Artery Smooth Muscle CellCytosolic Calcium. B. C. Linden, M.D., V. A. Porter, Ph.D.,E. Resnik, Ph.D., M. T. Rhodes, B.S., and D. N. Cornfield, M.D.,Departments of Surgery, University of Minnesota, Minneapo-lis, MN

21. Multiple Roles for Engrailed-1 during Mouse CalvarialDevelopment. T. J. Booker, B.S., P. Kraus, Ph.D., C. Tong,M.S., and C. A. Loomis, M.D., Ph.D., New York UniversitySchool of Medicine, New York, NY

22. Withdrawn.

23. Elastogenesis Plays a Signaling Role in Cell Differentia-tion in the Developing Pulmonary Vasculature. S. E.

ROGRAM

Mclean, M.D., R. K. Minkes, M.D., Ph.D., and R. P. Mecham,Ph.D., Departments of Surgery and Cell Biology, WashingtonUniversity, St. Louis, MO

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24. Redox Controls Fetal Hypoplastic Lung Growth. J. C.Fisher, B.A., D. E. Kling, Ph.D., T. B. Kinave, M.D., and J. J.Schnitzer, M.D., Ph.D., Massachusetts General Hospital, Har-vard Medical School, Boston, MA

25. Interleukin-11 Pretreatment Reduces Apoptosis and Mu-cosal Damage after Intestinal Ischemia–Reperfusion In-jury. K. A. Kuenzler, M.D., P. Y. Pearson, M.D., and M. Z.Schwartz, M.D., Alfred I. Dupont Hospital for Children, Wil-mington, DE

26. Caspase 3 Expression Is Altered in a Coculture Modelof Neuroblastoma and Hepatocytes. E. A. Beierle, M.D.,W. Dai, M.D., M. R. Langham, M.D., E. M. Copeland,M.D., and M. K. Chen, M.D., University of Florida, Gaines-ville, FL

7:30 am–9:30 am

Parallel Session ICrystal BallroomCategory: SHOCKModerators: Hobart W. Harris, M.D.

David A. Spain, M.D.

27. Rho Pathway Activation Increases Pulmonary Microvas-cular Permeability. P. A. Rothenbach, M.D., J. J. Schwartz,M.D., P. A. Carlson, Ph.D., H. Yin, Ph.D., and R. H. Turnage,M.D., Dallas VA Medical Center, Dallas, TX

28. HMG-1 Stimulates the Production of ProinflammatoryMediators by Primary Hepatic Nonparenchymal Cells.C. A. Mccloskey, M.D., K. Tracey, M.D., J. J. Baust, D. J. Gallo,and T. R. Billiar, M.D., University of Pittsburgh Medical Cen-ter, Pittsburgh, PA

29. Heat Shock Regulates NF-kB Activation. J. A. Johnson,B.S., W. J. Welch, Ph.D., and H. W. Harris, M.D., UCSF, SanFrancisco, CA

30. HMG CoA Reductase Inhibition Attenuates Endotoxin-Mediated Leukocyte–Endothelial Interactions and Re-duces iNOS Expression. M. Joyce, AFRCSI, C. Gang, M.D.,R. Casey, AFRCSI, D. Winter, M.D., A. Leahy, FRCSI, C.Kelly, FRCSI, and D. Bouchier Hayes, FRCSI, BeaumontHospital, Dublin, Ireland

31. Burn Injury Inhibits the Proliferation but Not the Acti-vation of CD81 T Cells in HYTCR Mice. D. M. Pilati, M.D.,B. A. Cairns, M.D., R. Maile, Ph.D., S. Deserres, B.A., J. A.Frelinger, Ph.D., and A. A. Meyer, M.D., Ph.D., University ofNorth Carolina, Chapel Hill, NC

32. Stimulation with Burn Serum Decreases Matrix Metal-loproteinase Production in Normal Dermal Fibroblasts.M. Spies, M.D., D. R. Mohan, Ph.D., R. E. Barrow, Ph.D., andD. N. Herndon, M.D., Department of Surgery, University ofTexas Medical Branch, Galveston Galveston, TX

33. Interleukin-6 Causes Endothelial Barrier Dysfunctionvia the Protein Kinase C Pathway. T. R. Desai, M.D., N. J.Leeper, B.S., K. L. Hynes, B.S., and B. L. Gewertz, M.D., TheUniversity of Chicago, Chicago, IL

SCIENTIFI

34. Dantrolene Downregulates the Gene Expression and Ac-tivity of the Ubiquitin-Proteasome Proteolytic Pathway

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in Septic Skeletal Muscle. C. J. Wray, M.D., X. Sun, M.D,Ph.D., G. I. Gang, M.D., and P. Hasselgren, M.D., Ph.D., Uni-versity of Cincinnati, Cincinnati, OH

7:30 am–9:30 am

Parallel Session IMitchell RoomCategory: GASTROINTESTINALModerators: Carlos Alvarez, M.D.

Kimberly S Kirkwood, M.D.

35. GLP-2 Enhances Intestinal Epithelial Restitution. A. P.Ramsanahie, M.D., A. Perez, M.D., A. U. Duensing, M.D., M. J.Zinner, M.D., S. W. Ashley, M.D., and E. E. Whang, M.D.,Brigham and Womens Hospital, Boston, MA

36. GATA-4 Activates the Intestinal Alkaline PhosphatasePromoter. N. S. Belaguli, Ph.D., and D. H. Berger, M.D.,Baylor College of Medicine, Houston, TX

37. Reduction of Serotonin Secretion by Carcinoid TumorCells after Raf-1 Induction. R. Sippel, M.D., B. Schnee-berger, B.S., and H. Chen, M.D., University of Wisconsin Med-ical School, Madison, WI

38. Role of Protein Kinase C (PKC) in Intestinal IschemicPreconditioning (IPC). J. W. Um, M.D., J. B. Matthews,M.D., J. C. Song, B.S., and E. C. Mun, M.D., Beth Israel Dea-coness Medical Center, Boston, MA

39. NF-kB Inhibition Decreases Hepatocyte Proliferationbut Does Not Alter Apoptosis in Obstructive Jaundice.M. A. Bird, M.D., P. A. Lange, M.D., C. M. Samson, B.S., M.Hayden, B.S., and K. E. Behrns, M.D., University of NorthCarolina, Chapel Hill, NC

40. Cytokines Modulate Bacteria–Enterocyte Interac-tions. D. J. Hess, M.D., M. J. Henry Stanley, Ph.D., E. A.Moore, B.S., and C. L. Wells, Ph.D., Department of Surgery,Minneapolis, MN

41. Voltage-Dependent Currents in Murine Colonic SmoothMuscle. M. Prasad, M.D., Oregon Health and Sciences Univer-sity and VA Medical Center, Portland, OR

42. Extrinsic Denervation Causes Absorptive AdrenergicHypersensitivity in the Canine Proximal Colon. M. L.Kendrick, M.D., T. Meile, N. J. Zyromski, M.D., T. Tanaka,M.D., K. D. Libsch, M.D., J. A. Duenes, B.A., and M. G. Sarr,M.D., Mayo Clinic, Rochester, MN

9:30 am–10:00 am

Refreshments/Poster ViewingRegency Ballroom

Authors to Set Up Oral Poster PresentationsMitchell Room

0:00 am–11:00 am

Local ProgramMedical College of Wisconsin

Crystal Ballroom

235ROGRAM

0:00 am

Welcome and Department FutureHenry A. Pitt, M.D., Professor and Chairman

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10:10 am

“The Role of Stretch Channels in CardiacContractile Dysfunction”

Alfred C. Nicolosi, M.D., AssociateProfessor, Cardiothoracic Surgery

10:20 am

“Obesity and Gallstones”Attila Nakeeb, M.D., Assistant Professor,

Minimally Invasive/GI Surgery

10:30 am

“Helper T-Cells in Tumor Immunity”Joel Shilyansky, M.D., Assistant Professor, Pediatric Surgery

10:40 am

“Relative Efficacy of Seatbelts and Airbagsin Preventing Aortic Injury”

Karen J. Brasel, M.D., M.P.H., Assistant Professor,Trauma/Critical Care

10:50 am

“NO in Allograft Rejection”Allan M. Roza, M.D., Professor, Transplant Surgery

11:00 am–12:00 pm

Founder’s Lecture“Allograft Acceptance and Tolerance”

Regency Ballroom I–IV

Thomas E. Starzl, M.D., Ph.D.Professor of Surgery, University of Pittsburgh,

Pittsburgh, Pennsylvania

2:00 pm–1:00 pm

LuncheonEmpire Ballroom

:00 pm–2:15 pm

Resident Research AwardsCrystal Ballroom

43. Toll-like Receptor-4 Signaling Mediates Pulmonary Neu-trophil Sequestration in Response to Gram-Positive Bac-terial Enterotoxin. C. M. Calkins, M.D., K. Barsness, M.D.,D. D. Bensard, M.D., A. Vasquez Torres, Ph.D., C. D. Raeburn,M.D., and R. C. Mcintyre, M.D., Department of Surgery, Uni-versity of Colorado, Denver, CO

44. Rho Activation Stimulates Embryonic Murine LungBranching Morphogenesis. K. A. Moore, M.D., S. Huang,M.D., Ph.D., and D. E. Ingber, M.D., Ph.D., Surgical ResearchLaboratory of Children’s, Hospital Boston, MA

45. Inosine Attentuates Gut Barrier Dysfunction and Sys-temic Injury Associated with Intestinal Ischemia–

236 SCIENTIFI

Reperfusion. J. F. Dowdall, FRCSI, D. C. Winter, FRCSI,A. W. Baird, Ph.D., and D. J. Bouchier Hayes, FRCSI, Beau-mont Hospital, Dublin, Ireland

2:15 pm–3:30 pm

Committee on IssuesCrystal Ballroom

Chairman: A. James Moser, M.D.“Promoting Our Vision: Advocacy and the Future ofAcademic Surgery”

Michael W. Mulholland, M.D., Ph.D.University of Michigan School of Medicine, Ann Arbor, MI

“Academic Surgeons: Clinical Productivity orEducation/Discovery”

Glenn Steele, Jr., M.D., Ph.D.Geisinger Health Systems, Danville, PA

“Academic Surgery: Separate and Apart or Equaland a Part”

Roger J. Bulger, M.D.Association of Academic Health Centers,Washington, DC

“Advocacy: Finding Your Voice and DeliveringYour Message”

Cynthia A. BrownAmerican College of Surgeons,Washington, DC

:30 pm–4:00 pm

Refreshments/Poster and Oral Poster ViewingRegency Ballroom/Mitchell Room

:00 pm–6:00 pm

Parallel Session IIMitchell RoomCategory: ORAL POSTER SESSIONModerators: J. Perren Cobb, M.D.

Program Committee, M.D.

46. The Magnitude of Coexistent Disease, Poor Health Habits,and the Use of Provider Services in Four Surgery-RelatedCancers. S. Chaudhry, M.D., MSHS, and C. Y. Ko, M.D., MSHS,Division of General Surgery, UCLA, Los Angeles, CA

47. Withdrawn.

48. Quantitation of Epidermal Growth Factor Receptor Ex-pression in Early Stage NSCLC by Real-Time PCR. J. D.Cunha, M.D., Ph.D., B. Parker, B.S., and M. A. Maddaus, M.D.,University of Minnesota, Minneapolis, MN

49. b-Cell-Specific Ablation of SSTR5 Results in Alterationin Body Weight, Insulin Secretion, and Glucose Regula-tion. X. Wang, Ph.D., M. A. Norman, M.D., F. J. Demayo,Ph.D., and F. C. Brunicardi, M.D., Baylor College of Medicine,Houston, TX

50. Preoperative Radiography and Rectal Biopsy in the Sur-gical Management of Children with Refractory Consti-pation. D. L. Segev, M.D., A. E. Stephen, M.D., C. Higgins,D. P. Ryan, M.D., and D. P. Doody, M.D., Massachusetts Gen-eral Hospital, Boston, MA

ROGRAM

51. In Vitro Complement Activation Favoring Soluble C5b-9Formation Alters Myocellular Sodium Homeostasis viaProtein Kinase C and Mitogen-Activated Protein Kinase.

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K. Okamoto, M.D., Ph.D., W. Wang, M.D., Ph.D., and D. O.Jacobs, M.D., M.P.H., Department of Surgery, Creighton Uni-versity School of Medicine, Omaha, NE

52. Induction of Apoptosis Results in Differential Expres-sion of Over 100 Genes without Effect on Caspases 3, 8,and 9 in Colon Cancer. S. Huerta, M.D., A. R. Jazirehi,C.L.S., M.S.C., D. M. Harris, Ph.D., B. Bonavida, Ph.D., D.Heber, M.D., Ph.D., and E. H. Livingston, M.D., UCLA Centerfor Human Nutrition, Los Angeles, CA

53. TGF-b Stimulates Collagen(I) in Vascular Smooth Mus-cle Cells via a Short DNA Element in the Proximal Col-lagen Promoter. K. Kubota, M.D., J. Okazaki, M.D., Ph.D., B.Liu, Ph.D., and C. K. Kent, M.D., Weill Medical College ofCornell Univesity, New York, NY

54. The Effect of Epinephrine on Neutrophil Apoptosis andPhenotype after Endotoxin. S. J. Hahm, M.D., D. Agnese,M.D., S. E. Calvano, M.D., S. Coyle, A. Kumar, and S. F. Lowry,M.D., Robert Wood Johnson Medical School Division of SurgicalSciences, New Brunswick, NJ

55. “Human” Bioartificial Skin Construct Engineered withan Acellular Dermis. N. E. Perlman, M.D., L. F. Strande,M.S., R. Eydelman, B.S., C. W. Hewitt, Ph.D., and A. J.Delrossi, M.D., Cooper Health System, Camden, NJ

4:00 pm–6:00 pm

Parallel Session IIOak RoomCategory: CLINICAL TRIALS/OUTCOMESModerators: Anthony Lucci, Jr., M.D.

Karen J. Brasel, M.D.

56. Withdrawn.

57. Pretreatment Health-Related Quality of Life (HRQL)Scores Are Associated with Complications in PatientsUndergoing Surgical Treatment of Colorectal Cancer.T. Anthony, M.D., L. Kim, M.D., G. Sarosi, M.D., F. Nwari-aku, M.D., L. Hynan, Ph.D., C. Jones, R.N., and R. H.Turnage, M.D., UT Southwestern Medical Center, Dallas,TX

58. K-ras Is Not a Sensitive Indicator of Recurrent ColonCancer. L. J. Kelsey, M.D., A. J. Senagore, M.D., T. J. Monroe,Ph.D., J. S. Thebo, Ph.D., P. Grady, M. A. Luchtefeld, M.D.,T. J. Vanderkooi, M.D., D. G. Kim, M.D., and A. J. Senagore,M.D., Spectrum Health General Surgery Residency, GrandRapids, MI

59. Cost Effectiveness of Gastric Bypass Roux-en-Y for AdultOnset Diabetes. D. P. Puopong, M.D., and C. D. Liu, M.D.,UCLA School of Medicine, Los Angeles, CA

60. Longer Length of Stay Is Not Correlated with InjurySeverity In Trauma Patients. K. J. Brasel, M.D., J. Rasmus-sen, B.S., and J. A. Weigelt, M.D., Medical College of Wisconsin,Milwaukee, WI

61. A Novel Intraoperative Score to Predict Outcome atEmergency Appendectomy. K. Power, MBChB, M. R. Kell,

SCIENTIFI

M.D., C. Sheilds, M.D., C. Power, M.D., W. O. Kirwan, M.D.,and H. P. Redmond, M.D., Cork University Hospital, Cork,Ireland

62. Impact of Abdominal CT Imaging on the Managementof Appendicitis: An Update. J. R. Fuchs, M.D., J. S.Schlamberg, M.D., M. J. Shortsleeve, M.D., and J. G.Schuler, M.D., Beth Israel Deaconess Medical Center, Bos-ton, MA

63. The Effect of Prolonged Pneumoperitoneum on Intraop-erative Urine Output. N. T. Nguyen, M.D., S. L. Lee, M.D.,and B. M. Wolfe, M.D., University of California Davis MedicalCenter, Sacramento, CA

:00 pm–6:00 pm

Parallel Session IIWalker RoomCategory: ONCOLOGYModerators: Terry C. Lairmore, M.D.

David M. Euhus, M.D.

64. Withdrawn.

65. Optimizing Dendritic Cell Antigen Presentation in RNA-Based Melanoma Immunotherapy. M. F. Kalady, M.D.,M. W. Onaitis, M.D., K. M. Padilla, B.A., S. Emani, B.S., D. S.Tyler, M.D., and S. K. Pruitt, M.D., Ph.D., Duke UniversityMedical Center, Durham, NC

66. Mutant Estrogen Receptors (ER) Discriminate SyntheticEstrogen Ligands from Estradiol (E2). S. L. Sugg, M.D.,J. J. Huang, J. Radek, Ph.D., and G. L. Greene, Ph.D., MedicalCollege of Wisconsin, Milwaukee, WI

67. Interferon Regulatory Factor-1 (IRF-1) Gene Therapyfor Breast Cancer. P. K. Kim, M.D., Y. Liu, M.D., T. R. Billiar,M.D., and J. H. Yim, M.D., Department of Surgery, Universityof Pittsburgh, Pittsburgh, PA

68. Combination Immunotherapy with IL-12 and Costimula-tory Molecules 4-1BB and CD40 Improves Survival in aMetastatic Colon Cancer Model. K. J. Weber, M.D., P. Gu,Ph.D., S. Chen, Ph.D., and C. M. Divino, M.D., Mount SinaiMedical Center, New York, NY

69. A Novel Function of Sp1 Transcription Factor: Repres-sion of p21 Gene Expression in Human Colon CancerCells. S. Y. Archer, M.D., J. J. Johnson, B.S., H. J. Kim, M.S.,Q. Ma, M.D., and R. A. Hodin, M.D., Beth Israel DeaconessMedical Center, Boston, MA

70. Vitamin E Succinate Inhibits Colorectal Liver Metastases.K. T. Barnett, M.D., F. D. Fokum, Ph.D., and M. P. Malafa, M.D.,Southern Illinois University School of Medicine, Springfield, IL

71. Transformation of Intestinal Epithelial Cells by Ras Re-sults in Down-Regulation of the Tight Junction Protein,Zonula Occludins-1 (ZO-1). A. S. Pearson, M.D., Y. G. Gi,M.S., Y. Li, B.S., K. Washington, M.D., R. D. Beauchamp, M.D.,and R. J. Coffey, M.D., Vanderbilt University Medical Center,Nashville, TN

:00 pm–6:00 pm

Parallel Session IICrystal BallroomCategory: PERIPHERAL VASCULARModerators: Vivian Gahtan, M.D.

Gilbert R. Upchurch, M.D.

237ROGRAM

72. Nitric Oxide Synthase Inhibition Is Associated with In-creased Matrix Metalloproteinase-9 Expression in Aortic

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Tissue. M. J. Eagleton, M.D., D. A. Peterson, B.A., V. Sullivan,M.D., J. W. Ford, B.A., K. Roelofs, D.V.M., J. C. Stanley, M.D.,and G. R. Upchurch Jr., M.D., University of Michigan HealthSystem, Ann Arbor, MI

73. a5b1 Regulation of Cell Migration Is Mediated by theCytoplasmic Domain of the a5 Subunit. D. P. Ly, M.D.,K. M. Zazzali, B.S., and S. A. Corbett, M.D., Robert WoodJohnson Medical School, New Brunswick, NJ

74. The Role of Phospholipase C (PLC) and Phosphatidyl-inositol 3-Kinase (PI3K) in Vascular Smooth Muscle CellMigration and Proliferation. B. Liu, Ph.D., H. Ihto, M.D., S.Yamamura, M.D., O. Louie, M.D., and K. C. Kent, M.D., Weill-Cornell Medical College, New York, NY

75. Interleukin-11 Attenuates Human Vascular SmoothMuscle Cell Proliferation. M. A. Zimmerman, M.D., C. H.Selzman, M.D., C. D. Raeburn, M.D., C. Hamiel, B.S., and A. H.Harken, M.D., University of Colorado Health Sciences Center,Denver, CO

76. Vascular Smooth Muscle Cells Derived from Atheroscle-rotic Human Arteries Exhibit Increased Adhesion, Mi-gration, and Proliferation. P. L. Faries, M.D., D. Rohan,M.D., M. Wyers, M.D., M. L. Marin, M.D., L. H. Hollier, M.D.,W. C. Quist, M.D., Ph.D., and F. W. Logerfo, M.D., Mount SinaiMedical Center, New York, NY; and Beth Israel DeaconessMedical Center, Boston, MA

77. Dexamethasone Inhibits Smooth Muscle Cell Migrationvia the ERK MAP Kinase Pathway and MMP Activity. C.Pross, M.D., J. S. Lane, M.D., M. M. Farooq, M.D., N. Angle,M.D., C. K. Tomono, A. E. Xavier, M.S., J. A. Freischlag, M.D.,R. E. Law, Ph.D., and H. A. Gelabert, M.D., Division of Vascu-lar Surgery, Los Angeles, CA

78. Nitric Oxide-Mediated Modulation of RhoA in Vascu-lar Smooth Muscle Cells. B. S. Zuckerbraun, M.D., T. R.Billiar, M.D., and E. Tzeng, M.D., University of Pittsburgh,Pittsburgh, PA

79. The Platelet Protein TSP-1 Stabilizes PDGF toPromote the Proliferative Phase of Tissue Repair.S. Krishnaswami, M.D., Q. P. Ly, M.D., and G. P. Tus-zynski, M.D., MCP Hahnemann University, Phila-delphia, PA

7:00 pm–9:00 pm

ReceptionMilwaukee Public Art Museum

SATURDAY, NOVEMBER 17, 2001

7:00 am–8:00 am

Continental Breakfast/Poster ViewingRegency Ballroom

8:00 am–10:00 am

Parallel Session IIIOak RoomCategory: EDUCATIONModerators: Anne T. Mancino, M.D.

238 SCIENTIFI

Scott R. Schell, M.D., Ph.D.

80. Predictors of Educational Outcome: Factors ImpactingPerformance on a Standardized Clinical Evaluation.

G. B. Nackman, M.D., J. Sutyak, M.D., S. Lowry, M.D., and C.Rettie, Ph.D., Robert Wood Johnson Medical School, NewBrunswick, NJ

81. Competency-Based Student Self-Assessment on a Sur-gery Rotation. D. S. Lind, M.D., V. Bui, M.S., T. Lam, M.D., E.Beierle, M.D., and E. M. Copeland III, M.D., Department ofSurgery, University of Florida, Gainesville, FL

82. Does the Subjective Evaluation of Surgical KnowledgeCorrelate with Written and Oral Exam Performance?S. S. Awad, M.D., K. R. Liscum, M.D., N. Aoki, M.D., S. H.Awad, M.D., B. G. Scott, M.D., and D. H. Berger, M.D., BaylorCollege of Medicine, Houston, TX

83. Operative Experience during Surgical Clerkship Corre-lates with a Match to a Categorical General SurgeryProgram. J. K. Aschenbrenner, M.D., B. J. Lewis, R.N., M.S.,L. F. Rikkers, M.D., FACS, and H. Chen, M.D., University ofWisconsin, Madison, WI

84. Ability of OSCE to Differentiate Surgical Residents,Medical Students, and Physician Assistant Students.H. W. Merrick, M.D., G. Nowacek, Ph.D., J. Boyer, G. Cerilli,M.D., P. Francis, Pa.C., A. Miller, Med.P.A., S. F. Gohara,M.D., and E. D. Staren, M.D., Medical College of Ohio, To-ledo, OH

85. 360-Degree Evaluation Instrument (3DEI): An Internet-Based Tool for Evaluating Surgical Resident Perfor-mance. S. B. Grek, M.S., T. C. Flynn, M.D., and S. R. Schell,M.D., Ph.D., University of Florida, Gainesville, FL

86. Intraoperative Communication of Residents with Fac-ulty: Perception versus Reality. R. D. Coats, M.D., M. H.Metzler, M.D., and R. S. Burd, M.D., Ph.D., Department ofSurgery, New Brunswick, NJ

87. Military Trauma Training Performed in a CivilianTrauma Center. M. A. Schreiber, M.D., J. B. Holcomb, M.D.,C. W. Conaway, M.D., K. D. Campbell, M.S., M. Wall, M.D., andK. L. Mattox, M.D., Baylor College of Medicine, Houston, TX

:00 am–10:00 am

Parallel Session IIIWalker RoomCategory: METABOLISM, ENDOCRINOLOGY, ANDNUTRITIONModerators: Mark A. Wilson, M.D.

Kathrin L. Mayer, M.D.

88. Gene Transfer of Hox D3 Increases Type I Collagen Ex-pression. S. L. Hansen, M.D., L. A. Uyeno, M.D., I. M. Cheung,B.A., D. M. Young, M.D., and N. J. Boudreau, Ph.D., Universityof California at San Francisco, San Francisco, CA

89. Changes in Myocellular Creatine (Cr) Content afterStarvation Are Associated with Reduced Serine Phos-phorylation of the Creatine Transporter. C. Zhao, M.D.,W. Wang, M.D., Ph.D., L. Shang, M.D., and D. O. Jacobs, M.D.,Surgical Research Laboratory, Department of Surgery, Creigh-ton University, Omaha, NE

90. Effect of Supplemental Ornithine on Wound Healing. H.Shi, M.D., Ph.D., R. S. Fishel, M.D., D. T. Efron, M.D., J. Z.

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Williams, M.D., M. H. Fishel, M.D., and A. Barbul, M.D., SinaiHospital of Baltimore and the Johns Hopkins University, Bal-timore, MD

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91. Short-Term Substrate Exposure Stimulates Brush Bor-der Alanine Transport by Transstimulation. M. Pan, M.D.,Ph.D., W. W. Souba, M.D., Ph.D., C. Lin, Ph.D., A. M. Karinch,Ph.D., and B. R. Stevens, Ph.D., Penn State University Collegeof Medicine, Hershey, PA

92. Effect of Oral Glutamine on Glutathione, IGF-I, andTGF-b1 in Rats. A. T. Johnson, M.D., Y. Kauffman, M.S., S.Luo, M.D., and V. S. Klimberg, M.D., Division of WomensOncology, University of Arkansas for Medical Sciences, LittleRock, AR

93. Upregulation of Arginase Expression in Wound-DerivedFibroblasts. M. B. Witte, M.D., A. Barbul, M.D., FACS, M.Schick, and H. Becker, M.D., FACS, Department of Surgery,University of Tuebingen, Tuebingen, Germany

94. TGF-b and IL-13 Induce Arginase Activity in Foam Cells.A. R. Barksdale, M.D., G. L. Gellin, M.S., S. C. Whitman, Ph.D.,P. R. Moreno, M.D., and J. B. Ochoa, M.D., University of Ken-tucky Lexington, KY; and University of Pittsburgh, Pittsburgh,PA

95. Elevated Baseline Expression of Transforming GrowthFactor b3 (TGF-b3) Relative to TGF-b1 Correlates withPeriod of Scarless Wound Repair in Gestational Mice.B. R. Edelman, B.A., A. D. Gordon, M.D., A. Radu, F. Lim, M.D.,and T. M. Crombleholme, M.D., Children’s Hospital of Phila-delphia, Philadelphia, PA

:00 am–10:00 am

Parallel Session IIICrystal BallroomCategory: PERIPHERAL VASCULARModerators: Ronald D. Robertson, M.D.

Michael M. Farooq, M.D.

96. Differential Expression of YAMA/CPP-32 by T-Lymphocytesin Popliteal Artery Aneurysm. A. Hingorani, M.D., S. Kal-lakuri, M.D., N. Markevich, M.D., T. Costa, M.D., W. Yorkovich,R.P.A., T. Jacob, Ph.D., and E. Ascher, M.D., Maimonides MedicalCenter, Brooklyn, NY

97. The Role of Neutrophils in Matrix Metalloproteinase-2and -9 Activation Following Acute Hindlimb Ischemia.B. E. Muhs, M.D., P. Gagne, M.D., G. Plitas, M.D., I. A. Ianus,M.D., M. Beudjekian, B.S., J. P. Shaw, M.D., and P.Shamamian, M.D., New York University School of Medicine,New York, NY

98. Decrease in Fibrin Content of Venous Thrombi in Selectinand IL-10-Deficient Mice. V. V. Sullivan, M.D., A. E. Hawley,M.S., D. M. Farris, L.V.T., B. S. Knipp, M.S., S. K. Wrobleski, B.S.,D. D. Myers Jr., D.V.M., J. B. Fowlkes, Ph.D., and T. W. Wake-field, M.D., University of Michigan, Ann Arbor, MI

99. IL-10 Reduces Monocyte Infiltration and MCP-1 Expres-sion in Rat Interposition Vein Grafting. J. S. Lane, M.D.,C. Pross, M.D., A. E. Xavier, M.S., A. R. Collins, Ph.D., R. E.Law, Ph.D., H. A. Gelabert, M.D., J. A. Freischlag, M.D., andM. M. Farooq, M.D., Divsion of Vascular Surgery, UCLA, LosAngeles, CA

00. Clinically Applicable Thermal Preconditioning Attenu-ates Ischaemia–Reperfusion Injury. P. H. Mccormick,

SCIENTIFI

AFRCSI, G. Chen, M.D., S. Tierney, FRCSI, C. Kelly, FRCSI,A. Leahy, FRCSI, and D. J. Bouchier Hayes, FRCSI, Depart-ment of Surgical Research, Dublin, Ireland

01. Carboxypeptidase A: A Serum Marker of Acute Mesen-teric Ischemia. A. O. Spinnickie, M.D., P. White, Ph.D., C.Gilvarg, Ph.D., S. Corbett, M.D., A. Graham, M.D., and G. B.Nackman, M.D., Robert Wood Johnson Medical School, NewBrunswick, NJ

02. Coagulation Activation after Supraceliac (SC) AorticCross-Clamping (AXC) Is Not Due to Cytokine Release.K. Pandurangi, M.D., P. V. Anagnostopoulos, M.D., I. I. Pipi-nos, M.D., and A. D. Shepard, M.D., Department of Surgery,Detroit, MI

03. Endovascular Approach to Abdominal Aortic AneurysmRepair Protects Patients from Postoperative SystemicImmune Inflammation. K. J. Sweeney, AFRCSI, D. Evoy,M.C.h., S. Sultan, M.C.h., D. J. Moore, M.C.h., G. Shanik,M.C.h., M. R. Kell, M.C.h., and J. V. Reynolds, M.C.h., Depart-ment of Clinical Surgery, Dublin, Ireland

:00 am–10:00 am

Parallel Session IIIMitchell RoomCategory: GASTROINTESTINALModerators: Diane M. Simeone, M.D.

James S. Goydos, M.D.

04. Caerulein-Induced Pancreatic Plasma Extravasation inRats Is Abolished by Neonatal Capsaicin Administra-tion. J. D. Nathan, M.D., Y. Wang, Ph.D., D. C. Mcvey, M.S.,S. R. Vigna, Ph.D., T. N. Pappas, M.D., and R. A. Liddle, M.D.,Duke University Medical Center Durham, NC

05. Synthetic Peptide YY ANALOG Is pH Dependent duringPancreatic Cancer Cell Growth Inhibition. A. Deganutti,M.S., and C. D. Liu, M.D., UCLA School of Medicine, LosAngeles, CA

06. Pancreatic Stellate Cell Activation and MMP Produc-tion during Rodent Acute Pancreatitis. W. Denham, M.D.,K. M. Murayama, M.D., T. Yokota, M.D., C. Pelham, R. J.Joehl, M.D., and R. H. Bell Jr., M.D., Northwestern UniversitySchool of Medicine, Chicago, IL

07. Alterations in Insulin Secretion of SSTR Knock-OutMice Using the Isolated Perfused Mouse PancreasModel. M. A. Norman, M.D., X. Wang, Ph.D., T. A. Tirone,M.D., and F. C. Brunicardi, M.D., Baylor College of Medicine,Houston, TX

08. Pancreatic-Associated Ascites Induces HepatocyteDeath Independent of Local Cytokine Production. M. M.Murr, M.D., J. Yang, M.D., A. Fier, B.A., and J. G. Norman,M.D., Tampa General Hospital, Tampa, FL

09. Withdrawn.

10. Survival Advantage in a Transgenic Spontaneous Pan-creatic Tumor Mouse Model When Treated with SEB andDendritic/Tumor Vaccine. E. J. Mcconnell, M.D., P.Mukherjee, Ph.D., M. Cathy, R. Ginardi, L. Pathangey, andS. J. Gendler, Ph.D., Department of Surgery, Mayo ClinicScottsdale, Scottsdale, AZ

11. Induction of NF-kB, IkB-a, and iNOS in Rat Gastric Mu-

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cosa during Endotoxemia. K. Helmer, M.D., L. Chang, B.S.,Y. Cui, M.D., and D. W. Mercer, M.D., UT Houston MedicalSchool, Houston, TX

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10:00 am–10:30 am

Refreshments/Poster ViewingRegency Ballroom

10:30 am–11:15 am

Presidential AddressCrystal Ballroom

“From Led to Leader”David H. Berger, M.D.

1:15 am–12:00 pm

Invited Guest SpeakerCrystal Ballroom

“The Leadership Principles of Abraham Lincoln”F. Charles Brunicardi, M.D.

Methodist Hospital/Baylor College of Medicine, Houston, TX

12:00 am–1:00 pm

LuncheonEmpire Ballroom

1:00 pm–3:00 pm

Parallel Session IVCrystal BallroomCategory: SHOCKModerators: Siobhan A. Corbett, M.D.

Paul E. Bankey, M.D.

12. The Effect of Tonicity and Hypertonic Solutions on Mi-crovascular Permeability. G. P. Victorino, M.D., Universityof California Davis, East Bay, Oakland, CA

13. Splanchnic Hypoperfusion-Directed Therapies inShock: A Prospective, Randomized Trial. S. M. Hameed,M.D., M.P.H., O. Kirton, M.D., M. Brown, M.S.N., D. Shatz,M.D., N. N. Namias, M.D., M. G. Mckenney, M.D., D. Sleeman,M.D., E. Ginzburg, M.D., A. Varon, M.D., and S. M. Cohn, M.D.,University of Miami School of Medicine, Miami, FL

14. Local and Systemic Roles of P-Selectin and ICAM-1 inHepatic Ischemia–Reperfusion Injury. K. M. Monson,M.D., R. E. Dean, M.D., and E. Crockett, Ph.D., Department ofSurgery, Michigan State University, East Lansing, MI

15. Differential Alterations in Intestinal Permeability Fol-lowing Trauma–Hemorrhage: Accumulation of Macro-molecules in the Lymphatic Compartment. J. F. Kuebler,M.D., B. Toth, M.D., K. I. Bland, M.D., P. Wang, M.D., and I. H.Chaudry, Ph.D., University of Alabama, Birmingham, AL

16. Acute Pancreatitis Provokes an Antigen-DependentProinflammatory Systemic T-Cell Response. K. J.Sweeney, AFRCSI, M. R. Kell, FRCSI, T. R. Murphy, M.B., andJ. V. Reynolds, M.C.H., Department of Clinical Surgery, Dub-lin, Ireland

17. Skeletal Muscle Creatine Transport in Sepsis. M. A. Jobst,M.D., W. Wang, M.D., Ph.D., and D. O. Jacobs, M.D., CreightonUniversity School of Medicine Omaha, NE

118. Hepatic Endosomal Trafficking of Lipoprotein-BoundEndotoxin in Rats. H. W. Harris, M.D., S. Brady, B.S., and

240 SCIENTIFI

J. H. Rapp, MD. UCSF, San Francisco, CA

119. Deficiency in gd T-Lymphocytes Compromises the Abil-ity of Mice to Survive Sepsis. L. Watkins, B.A., C. S. Chung,

Ph.D., G. Y. Song, B.S., J. Lomas, M.S., E. V. Cahoone, M.D.,and A. Ayala, Ph.D., Rhode Island Hospital–Brown University,Providence, RI

1:00 pm–3:00 pm

Parallel Session IVOak RoomCategory: TRANSPLANT/IMMUNOLOGYModerators: David A. Geller, M.D.

Kim M. Olthoff, M.D.

120. Transplantation of Reduced Liver Mass Results in Pro-longed Regenerative Response, but Reduces Toleranceto Cold Preservation. F. Debonera, B.S., X. Que, M.D., X.Aldeguer, M.D., A. E. Gelman, B.S., G. Zamir, M.D., M. Martin,B.S., A. Shaked, M.D., and K. M. Olthoff, M.D., Hospital of theUniversity of Pennsylvania, Philadelphia, PA

121. Thymoglobulin’s Protective Effect on the Liver duringCold Preservation. M. Hu, M.D., R. P. Thomas, M.D., L. E.Sower, Ph.D., and J. A. Daller, M.D., Ph.D., The University ofTexas Medical Branch, Galveston, TX

122. A Novel Method for the in Vitro Production of a HumanSkin Equivalent Using a Platelet Matrix. K. M. Schuster,M.D., M. Goldenberg, M.D., C. Tai, M.D., L. Strande, M.S., andC. W. Hewitt, Ph.D., University of Medicine and Dentistry ofNew Jersey–Robert Wood Johnson Medical School at CamdenCooper Hospital, University Medical Center, Camden, NJ

123. Mandibular Augmentation in Dogs Using TransplantedAutologous Cultured Bone Marrow Stromal Cells—ALong-Term Study. M. H. Mankani, M.D., S. A. Kuznetsov,Ph.D., and P. Gehron Robey, Ph.D., University of California atSan Francisco, San Francisco, CA

124. A New in Vitro Model to Study Endothelial Injury. C.Wilasrusmee, M.D., M.S.C., J. Siddiqui, M.S., S. Bhupinger,M.D., S. Kittur, M.D., S. Wilasrusmee, M.D., D. S. Kittur, M.D.,S.C.D., SUNY Upstate Medical University, Syracuse, NY

125. Expression Profiling of Acute Rejection in Human Pan-creas Allografts by Microarrays. L. M. Jacobson, B.S., D.Heisey, Ph.D., R. W. Sands, B.S., and J. S. Odorico, M.D.,Division of Transplantation, University of Wisconsin, Madison,WI

126. CD1-Positive Natural Killer (NK) T Cells Are Requiredfor Development of Oral and Portal Venous Tolerance.J. A. Margenthaler, M.D., K. Landeros, B.S., and M. Flye, M.D.,Ph.D., Washington University School of Medicine, St. Louis,MO

127. Novel Hydrodynamic Plasmid DNA Gene Therapy in theLiver Transplant Setting. G. Tsoulfas, M.D., Y. Takahashi,M,D,, D, Liu, Ph.D., G. P. Yagnik, B.S., T. Wu, M.D., Ph.D., Q.Zhang, B.S., N. Murase, M.D., and D. A. Geller, M.D., StarzlTransplantation Institute, University of Pittsburgh MedicalCenter, Pittsburgh, PA

1:00 pm–3:00 pm

Parallel Session IVMitchell Room

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Category: PERIPHERAL VASCULARModerators: Robert W. Thompson, M.D.

Gary B. Nackman, M.D.

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128. Abnormal Mitochondrial Respiration in Skeletal Muscleof Patients with Peripheral Arterial Disease. I. I. Pipinos,M.D., V. G. Sharov, M.D., A. Todor, M.D., P. V. Anagnostopou-los, M.D., H. N. Sabbah, Ph.D., and A. D. Shepard, M.D., HenryFord Hospital, Detroit, MI

29. Correlation of Platelet Reactivity and Endothelial Func-tion in Young Patients with Type-1 Diabetes. M. R. Joyce,AFRCSI, K. Moore, M.D., G. Mcgreal, FRCSI, C. Thompson,M.D., M. Dooley, BSCI, C. J. Kelly, Ph.D., A. Leahy, FRCSI, D.Cox, Ph.D., and D. Bouchier Hayes, FRCSI, Department ofSurgery, Dublin, Ireland

30. Folic Acid Protects Against Cigarette-Smoking-InducedEndothelial Dysfunction. H. L. O’Grady, AFRCSI, P. McCor-mick, AFRCSI, P. Fitzgerald, C. Kelly, FRCSI, A. Leahy,FRCSI, and D. J. Bouchier Hayes, FRCSI, Department of Sur-gical Research, Dublin, Ireland

31. Luminal Thrombus Disrupts Nitric Oxide-DependentEndothelial Function in Vivo. M. R. Davis, M.D., D. P.Ortegon, M.D., W. D. Clouse, M.D., J. D. Decaprio, M.D., A. C.Chiou, M.D., J. D. Kerby, M.D., Ph.D., R. T. Hagino, M.D., andV. S. Kashyap, M.D., Wilford Hall Medical Center, LacklandAFB, TX

32. Chlorhexidine Gluconate Gel Protects Exposed Nervesduring the Application of BioGlue Surgical Adhesive.S. A. Lemaire, M.D., L. D. Conklin, M.D., Z. C. Schmittling,M.D., A. Undar, Ph.D., J. S. Coselli, M.D., B. A. Deady, B.S.,and C. D. Fraser, Jr., M.D., Baylor College of Medicine, Hous-ton, TX

33. Intimal Hyperplasia Following Carotid Endarterectomyin an Insulin-Resistant Rat Model. T. P. Smith, M.D., C. P.Cruz, M.D., A. T. Brown, Ph.D., J. F. Eidt, M.D., and M. M.Moursi, M.D., University of Arkansas for Medical Sciences,Little Rock, AR

34. Early Expression of TGF-b Precedes Shear-Induced In-timal Thickening. T. M. Singh, M.D., E. Sho, M.D., Ph.D., M.Sho, M.D., C. Xu, M.D., Ph.D., H. Masuda, M.D., Ph.D., andC. K. Zarins, M.D., Stanford University Medical Center, Stan-ford, CA

135. Differential Mechanical Activation of MAPK in IntactBlood Vessels. M. A. Curi, M.D., M.P.A., C. L. Skelly, M.D.,S. L. Meyerson, M.D., E. Lee, B.S., J. Lanahan, B.S., D. Jay-akar, M.D., H. S. Bassiouny, M.D., and L. B. Schwartz, M.D.,University of Chicago Hospitals, Chicago, IL

1:00 pm–3:00 pm

Parallel Session IVWalker RoomCategory: ONCOLOGYModerators: Anthony Lucci, Jr., M.D.

Lawrence T. Kim, M.D.

136. Parallel Signaling Pathways Regulate NF-kB Activationin Human Pancreatic Cancer Cells. S. A. Shah, M.D., M. W.Potter, M.D., M. H. Hedeshian, M.D., and M. P. Callery, M.D.,University of Massachusetts Medical School, Worcester, MA

137. Somatostatin Receptor Subtype-2 Gene Therapy Inhib-its Growth of Pancreatic Cancer in Vitro. W. E. Fisher,

SCIENTIFI

M.D., F. Amaya Manzanares, B.S., D. H. Berger, M.D., andF. C. Brunicardi, M.D., Department of Surgery, Baylor Collegeof Medicine, Houston, TX

138. Differential Heparanase-1 Gene Expression in Malig-nant and Benign Pheochromocytomas. R. M. Quiros, M.D.,A. W. Kim, M.D., D. Patel, B.S., P. Gattuso, M.D., X. Xu, Ph.D.,and R. A. Prinz, M.D., Department of General Surgery, RushPresbyterian St. Lukes Medical Center, Chicago, IL

139. Negative Regulation of Angiogenesis by a GrowthArrest-Specific Homeobox Gene. D. H. Gorski, M.D., Ph.D.,UMDNJ–Robert Wood Johnson Medical School, New Bruns-wick, NJ

140. Vitamin E and the Y4 Agonist BA-129 Decrease ProstateCancer Growth and VEGF Production. P. Somasundar,M.D., A. Balsubramaniam, Ph.D., A. Yu, M.D., A. T. Rose,M,D,, L, Vona Davis, Ph.D., and D. W. Mcfadden, M.D., WestVirginia University, Morgantown, WV

141. Thrombospondin-1 (TSP-1) Up-Regulates MatrixMetalloproteinase-9 (MMP-9) in Gastric Cancer. D. Albo,M.D., Ph.D., T. Shinohara, M.D., Ph.D., and G. Tuszynski,Ph.D., The UTMD Anderson Cancer Center, Houston, TX

142. Mechanisms of Interferon-g-Induced Dendritic Cell (DC)Apoptosis. A. Stanford, M.D., Y. Chen, Ph.D., X. Zhang, R.Hoffman, Ph.D., R. Zamora, Ph.D., and H. Ford, M.D., Chil-dren’s Hospital of Pittsburgh, Pittsburgh, PA

43. Development and Preclinical Evaluation of a BCG-Based MUC1 Vaccine. M. A. Chung, M.D., Ph.D., Y. Luo,Ph.D., M. O. Donnell, M.D., C. Rodriguez, B.S.C., S. Sharma,MBBS, Ph.D., and H. R. Chang, M.D., Ph.D., Women andInfants Hospital Providence, RI

:00 pm–3:30 pm

Refreshment Break—View PostersRegency Ballroom

:30 pm

Authors Remove Posters

:30 pm–5:00 pm

Annual Business Meeting (Members Only)Crystal Ballroom

6:30 pm–7:15 pm

Presidential ReceptionEmpire Ballroom Foyer

7:15 pm–10:00 pm

Presidential BanquetEmpire Ballroom

POSTER SESSION

P1. Withdrawn.

P2. Chlorhexidine Gluconate Gel Protects the Myocar-dium and Sinoatrial Node during Application of Bio-Glue Surgical Adhesive. S. A. Lemaire, M.D., L. D. Con-klin, M.D., Z. C. Schmittling, M.D., A. Undar, Ph.D., J. S.Coselli, M.D., F. J. Clubb Jr., D.V.M., B. A. Deady, B.S., andC. D. Fraser Jr., M.D. Baylor College of Medicine, Houston,

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TX

P3. Enhanced Neutrophil Adhesion Molecule Expression Isan Early Priming Response to Diverse Insults. D. A. Par-

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trick, M.D., D. R. Meldrum, M.D., C. C. Silliman, M.D., andE. E. Moore, M.D., University of Colorado, Denver, CO

P4. Myocardial Protection with ATP-Sensetive Potassium-Channel Opener Is as Effective as St. Thomas Solution inthe Neonatal Rabbit Heart. J. Feng, M.D., H. Li, M.D., and E.Rosenkranz, M.D., University of Miami, Miami, FL

P5. Elevated Expression Levels of P-Selectin and Inter-cellular Adhesion Molecule-1 Are Associated withIschemia/Reperfusion Injury in Patients UndergoingOpen Aortic Aneurysm Repair. H. Liu, M.D., N. J. Morris-sey, M.D., I. Kantonen, M.D., R. Kahn, M.D., and L. Hollier,M.D., Mount Sinai Medical Center, New York, NY

P6. Morbidity and Recovery Following Sentinel LymphNode Dissection vs Complete Axillary Lymph Node Dis-section. A. Azizzadeh, M.D., P. R. Kelemen, M.D., L. L. Wil-son, B.S., and A. Lucci, M.D., Baylor College of Medicine,Houston, TX

P7. Standardization of Family History Data Collection in anAcademic Medical Center. J. F. Calland, M.D., C. R.Seward, B.S., D. Simpson, B.S., D. Benjamin, M.D., M.P.H.,and R. B. Adams, M.D., FACS, Department of Surgery, Uni-versity of Virginia Health System, Charlottesville, VA

P8. Cholecystectomy in Patients with Previous Spinal CordInjury: The Department of Veterans Affairs Experience.J. B. Smith, B.S., H. U. Ahmed, B.M., B.C.H., R.A., D. J.Rudderow, M.D., W. E. Longo, M.D., K. S. Virgo, M.B.A., Ph.D.,and F. E. Johnson, M.D., St. Louis University School of Medi-cine, St. Louis, MO

P9. Enteral Tolerance after Severe Trauma Is ReliablyAchieved by a Standardized Protocol. R. A. Kozar, M.D.,Ph.D., E. E. Moore, M.D., K. A. Kudsk, M.D., G. J. Jurkovich,M.D., and F. A. Moore, M.D., University of Texas–Houston,Houston, TX

10. Evaluation of Binocular Video Projection (Heads-Up)Glasses for Laparoscopy: Neurometric Skills Testingand Surgeon Satisfaction. G. J. Winkel, M.D., W. R. Rout,M.D., and S. R. Schell, M.D., Ph.D., University of Florida,Gainesville, FL

11. The Role of Substance P (SP) in Intraabdominal Adhe-sion Formation. A. B. Fruin, M.D., K. L. Reed, Ph.D., A. F.Stucchi, Ph.D., S. E. Leeman, Ph.D., A. C. Gower, M.S., andJ. M. Becker, M.D., Boston University Medical Center, Boston,MA

12. Withdrawn.

13. Pancreatic Elastase Is a Mannose-Binding Lectin Se-creted from Pancreas. S. A. Patel, M.D., P. Rengabashyam,M.D., Z. Fan, M.D., and M. E. Zenilman, M.D., SUNY–Downstate Medical Center, Brooklyn, NY

14. Ciglitazone Inhibits Growth and Induces Apoptosis inHuman Pancreatic Cancer Cells. G. Eibl, M.D., H. A.Reber, M.D., M. N. Wente, M.D., and O. J. Hines, M.D., De-partment of General Surgery, UCLA School of Medicine, LosAngeles, CA

15. Ultrastructural Changes in Cirrhotic and NoncirrhoticPatients Due to Heptatectomy. C. Wilasrusmee, M.D.,

242 SCIENTIFI

M.S.C., S. Siritheptawee, M.D., P. Sopon, Ph.D., W. Limp-thong, M.S., S. Wilasrusmee, M.D., and S. Kanchanapanjapon,M.D., Ramathibodi Hospital Mahidol University, Bangkok,

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Thailand; and SUNY Upstate Medical University, Syracuse,NY

16. Peptide YY Improves Acute Pancreatitis by Restoringthe Apoptosis/Necrosis Ratio. A. Yu, M.D., L. Vonadavis,Ph.D., P. Somasundar, M.D., and D. W. Mcfadden, M.D., WestVirginia University, Morgantown, WV

17. Influence of Pericardial Restraint on Right Atrial Me-chanics during Acute Pulmonary Hypertension. H. S.Maniar, M.D., S. M. Prasad, M.D., M. L. Lester, B.S., and M. R.Moon, M.D., Washington University School of Medicine, St.Louis, MO

18. Gut Mucosal Homeostasis after Starvation. X. Wu, M.D.,S. Marcus, M.D., J. Song, M.D., H. N. David, M.D., T. C. James,M.D., and W. E. Steven, M.D., Shriners Burns Hospital andDepartment of Surgery, University of Texas Medical Branch,Galveston, TX

19. Enterocyte Apoptosis and Intestinal Adaptation afterSmall Bowel Resection Occur Independent of Fas Ex-pression. D. P. Obrien, M.D., L. A. Nelson, M.D., C. J. Kemp,B.S., C. R. Erwin, Ph.D., and B. W. Warner, M.D., ChildrensHospital Medical Center Division of Pediatric Surgery, Cincin-nati, OH

20. Heat Shock Response Inhibits the Neuroendocrine Re-sponse to Surgical Stress in Rats. B. B. Oneill, M.D., W. J.Welch, Ph.D., and H. W. Harris, M.D., UCSF, San Francisco,CA

21. Induction of Apoptosis in HL-60 Cells by ArachidonicAcid and Eicosapentaenoic Acid. R. C. Gillis, M.S., B. J.Daley, M.D., B. L. Enderson, M.D., and M. D. Karlstad, Ph.D.,University of Tennessee Medical Center, Knoxville, TN

22. v-3 Fatty Acid-Mediated Reduction of TNF-a and PGE2

Production by LPS-Stimulated Macrophages Is Inde-pendent of IL-10. E. S. Ong, M.D., T. Babcock, M.S., W. S.Helton, M.S., and J. Espat, M.D., University of Illinois atChicago, Chicago, IL

23. Taurolidine: A Novel Treatment for Colorectal Can-cer. M. J. Osullivan, AFRCSI, J. H. Wang, Ph.D., Q. D. Wu,M.S.C., W. O. Kirwan, FRCSI, and P. Redmond, FRCSI,Department of Academic Surgery, Cork University Hospital,Cork Ireland

24. Taurolidine Inhibits Angiogenesis. M. J. Osullivan,AFRCSI, J. H. Wang, Ph.D., W. O. Kirwan, FRCSI, and P.Redmond, FRCSI, Department of Academic Surgery, CorkUniversity Hospital, Cork, Ireland

25. Taurolidine Inhibits Breast Cancer in Vitro and inVivo. M. J. Osullivan, AFRCSI, J. H. Wang, Ph.D., Q. D. Wu,M.S.C., W. O. Kirwan, FRCSI, and P. Redmond, FRCSI,Department of Academic Surgery, Cork University Hospital,Cork, Ireland

26. Identification of a Molecular Fingerprint Characteriz-ing Src Transformation Relevent to Human Colon Can-cer. R. Malek, Ph.D., N. H. Lee, Ph.D., R. B. Irby, Ph.D., andT. J. Yeatman, M.D., H. Lee Moffitt Cancer Center at theUniversity of South Florida and The Institute For GenomicResearch, Tampa, FL

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27. Quantification of Her 2/Neu Gene Amplification in Colonand Pancreas Carcinoma Cell Lines Using a Novel PCR/LDR Technique. D. R. Nathanson, M.D., A. T. Culliford,

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M.D., G. Nash, M.D., and P. Paty, M.D., Memorial Sloan–Kettering Cancer Center, New York, NY

28. Effect of Alternate Chemotherapy Sequencing Regi-mens on Molecular and Cellular Responses in Pancre-atic Cancer. B. N. Fahy, M.D., S. Virudachalam, M.S., andR. J. Bold, M.D., UC Davis Cancer Center, Sacramento, CA

29. Promoter Region Hypermethylation of Tumor Suppres-sor Genes in Benign Breast Epithelium from Asymptom-atic Risk-Defined Women. D. M. Euhus, M.D., S. ZochbauerMuller, M.D., C. Lewis, Ph.D., A. F. Gazdar, M.D., and J.Minna, M.D., UT Southwestern Medical Center, Dallas, TX

30. Adjunctive Chemotherapy Complements Cryoablationin Colon Cancer. D. G. Nair, M.D., J. E. Denny, M.D., W.Yang, Ph.D., and T. S. Ravikumar, M.D., Albert Einstein Col-lege of Medicine, Bronx, NY

31. The Mechanism of Action of Endostatin on Quiescentand Stimulated Endothelial Cells. S. H. Teh, M.D., FRCSI,B. Brankin, Ph.D., L. M. Kelly, AFRCSI, A. W. Lee, B.S.C.,E. W. Mcdermott, M.C.H., FRCSI, N. O. Higgins, M.C.H.,FRCSI, and A. D. Hill, M.C.H., FRCSI, Department of Surgery,St. Vincent’s University Hospital, Dublin, Ireland

32. Defects in TGF-b Signaling by Smad4 and ELF Spec-trins Are Associated with Gastric Carcinogenesis. C. J.Fox, M.D., Y. Tang, Ph.D., C. D. Bhanumaphy, Ph.D., S.Danovitch, M.D., T. Fleury, M.D., B. Mishra, M.D., C. Deng,Ph.D., A. N. Sidawy, M.D., and L. Mishra, M.D., Departmentof Surgery, Walter Reed Army Medical Center, Washington,DC

33. Tamoxifen Increases the Efficacy of Chemotherapy andRadiotherapy in Lewis Lung Carcinoma. M. Bresnihan,AFRCSI, J. Harmey, Ph.D., T. Walsh, FRCSI, M. Moriarty,and D. J. Bouchier Hayes, FRCSI, Department of SurgicalResearch, Dublin, Ireland

34. Withdrawn.

35. Modulation of Regulatory Genes in A375 MelanomaCells That Have Survived Treatment with Gemcitabine.F. Shaheen, M.D., E. D. Staren, M.D., Ph.D., R. Assad, M.D.,and D. P. Braun, Ph.D., Medical College of Ohio, Toledo, OH

36. Established Tumors Escape Elimination Despite Activa-tion of Specific T Cells. I. Brown, B.A., C. A. Jackson, M.D.,P. Yu, M.D., H. Schreiber, M.D., Ph.D., and J. Shilyansky,M.D., Medical College of Wisconsin, Milwaukee, WI

37. Gene Expression Changes and Growth Inhibition of Hu-man Pancreatic Cancer with COX-2 Enzyme Inhibition.A. Deganutti, M.S., R. E. Saxton, Ph.D., and C. D. Liu, M.D.,UCLA School of Medicine, Los Angeles, CA

38. ErbB2/STAT3 Interaction Correlates with S-Phase Pro-gression IN THE Pancreatic Ductal AdenocarcinomaCell Line MIA PaCa-2. D. T. Dearmond, M.D., M. G. Brat-tain, Ph.D., W. E. Strodel, M.D., and J. W. Freeman, Ph.D.,University of Texas Health Science Center at San Antonio, SanAntonio, TX

39. Axillary Sentinel Lymph Node Biopsy in Stage I–IIBreast Cancer with Lymphozuran Blue Dye Technique

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Only. P. P. G. Curcillo II, M.D., Department of Surgery, Jef-ferson Medical College, Philadelphia, PA

40. Functional Significance of Adaptor Protein CRKL in

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Lung Cancer Oncogenesis. M. W. Onaitis, M.D., S. Emani,B.S., A. Pendergast, Ph.D., and D. S. Tyler, M.D., Duke Uni-versity, Durham, NC

41. Esophagogastric Adenocarcinoma in a TransgenicModel Expresses Cyclooxygenase-2. J. Shim, B.A., C. K.Byrnes, M.B., B.C., P. H. Nass, Ph.D,. J. W. Harmon, M.D., A.Bahadursingh, M.B., B.S., and M. D. Duncan, M.D., JohnsHopkins University, Baltimore, MD

42. Inhibition of Adhesion Signaling Combined with Ioniz-ing Radiation (IR) Synergizes to Induce Apoptotic CellDeath. J. D. Rovin, M.D., C. P. Bowen, M.D., T. Parsons,Ph.D., and R. B. Adams, M.D., University of Virginia HealthSystems, Charlottesville, VA

43. Effect of VEGF-Mediated Angiogenesis Inhibition onPostoperative Wound Healing. C. D. Roman, M.D., H.Choy, M.D., D. H. Johnson, M.D., L. B. Nanney, Ph.D., C.Riordan, M.D., and R. D. Beauchamp, M.D., Vanderbilt Uni-versity Medical Center, Nashville, TN

44. Modulation of Integrin Subunits by Heparin. M. S. DaSilva, M.D., L. W. Blystone, M.S., W. R. Fish, Ph.D., J. A.Horton, B.S., S. D. Blystone, Ph.D., and M. Sobel, M.D., SUNYUpstate Medical University, Syracuse, NY

45. Sphingose-1-Phosphate Induces GaI-Coupled, PI3K-Dependent Smooth Muscle Cell Migration. W. Tanski,M.D., E. Roztocil, B.A., and M. G. Davies, M.D., Ph.D., Uni-versity of Rochester, Rochester, NY

46. A Novel Mechanism for Hypoxia-Induced Proliferationof Vascular Smooth Muscle Cells. S. C. Lin, M.D., A. Nad-ershahi, M. Sarkar, B.S., and R. Sarkar, M.D., Ph.D., UCSF,San Francisco, CA

47. Catecholamines Do Not Modulate Peripheral Perme-ability Responses to Bradykinin in Heart Failure. J. L.Hunter, M.D., J. R. Lakey, B.S., D. Moyer, B.A., M. I. Towns-ley, Ph.D., and D. L. Dyess, M.D., University of South Ala-bama, Mobile, AL

48. Cotinine-Induced Alterations in Programmed CellDeath and Migration of Vascular Smooth Muscle Cells(VSMCS). A. Hingorani, M.D., S. Kallakuri, M.D., N. Markev-ich, M.D., T. Costa, M.D., Y. Khanimov, M.D., W. Yorkovich,R.P.A., T. Jacob, Ph.D., and E. Ascher, M.D., MaimonidesMedical Center, Brooklyn, NY

49. Early Expression of Uteroglobin after Adenoviral-Mediated Gene Transfer Inhibits Smooth Muscle CellProliferation after Rat Carotid Balloon Injury. S. V.Ryan, M.D., M. Naji, M.S., B. Koeberlein, A.S., R. A. Larson,M.D., J. V. Lombardi, M.D., and M. A. Golden, M.D.,University of Pennsylvania School of Medicine, Philadelphia,PA

50. Activation of Endothelial Cells with Expression ofIntracellular Adhesion Molecule (ICAM) and Vas-cular Cell Adhesion Molecule (VCAM) in Response toNicotine in Vitro. G. Albaugh, D.O., B. Kann, M.D., L. F.Strande, M.S., S. Heimburger, B.A., C. W. Hewitt, Ph.D.,and J. B. Alexander, M.D., Cooper Health System, Cam-den, NJ

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51. Endothelial Cell Migration and Integrin Expression Dif-fer Among Species. C. Chang, Ph.D., S. Vanguri, B.S., I. A.Entersz, O. J. Imegwu, M.D., S. M. Corbett, M.D., A. M. Gra-

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ham, M.D., and G. B. Nackman, M.D., Robert Wood JohnsonMedical School, New Brunswick, NJ

52. Transfection Efficiency of Intraarterial vs Intramuscu-lar Naked Plasmid DNA-Mediated Gene Transfer inIschemic Skeletal Muscle. D. S. Chang, M.D., L. S. Brevetti,M.D., R. Sarkar, M.D., Ph.D., and L. M. Messina, M.D., UCSFDivision of Vascular Surgery, San Francisco, CA

53. Preliminary Results of Placement of a New Nitinol In-ferior Vena Cava Filter. A. Hingorani, M.D., E. Ascher,M.D., F. Kallakuri, M.D., Y. Gunduz, M.D., N. Markevich,M.D., T. Costa, M.D., Y. Khanimov, M.D., and W. Yorkovich,R.P.A., Maimonides Medical Center, Brooklyn, NY

54. The Development of Fluorescent Human Cultured Kera-tinocyte Grafts Using a Green Fluorescent Protein Adeno-viral Construct. A. M. Ward, B.S., S. Hultman, M.D., R. Maile,Ph.D., S. Deserres, B.A., L. A. Cramer, Ph.D., D. M. Pilati, M.D.,J. A. Frelinger, Ph.D., A. A. Meyer, M.D., Ph.D., and B. A. Cairns,M.D., University of North Carolina, Chapel Hill, NC

55. Serum Vascular Endothelial Growth Factor: A Surveil-lance Marker for Acute Cellular Rejection in PediatricCardiac Transplantation. L. P. Abramson, M.D., E. Pahl,M.D., L. Huang, M.D., V. Stellmach, Ph.D., R. A. Superina,M.D., R. M. Arensman, M.D., and S. E. Crawford, M.D., Chil-dren’s Memorial Hospital, Chicago, IL

56. Increased Matrix Metalloproteinase (MMP)-9 in Sera ofRats with D-Galactosamine-Induced Fulminant HepaticFailure (FHF). C. Camacho, M.D., R. Wharen, M.D., J.Steers, M.D., and J. H. Nguyen, M.D., Mayo Clinic, Jackson-ville, Jacksonville, FL

P57. Near-Infrared Spectrometric Determination of BloodpH. N. A. Rosen, M.D., W. E. Charash, M.D., Ph.D., and E. F.Hirsch, M.D., Boston University Medical Center, Boston, MA

P58. Local and Remote Ischemia–Reperfusion Injury IsStrongly Abrogated In Transgenic Mice OverexpressingHuman C-1 Inhibitor. Authors Unknown

P59. Disruption of the Nramp1 Gene in Kupffer Cells Pro-

244 SCIENTIFI

tects the Mouse Liver from the Early Phase of Ischemia/Reperfusion Injury. S. Wyllie, Ph.D., P. Seu, M.D., P. Gros,

M.D., Ph.D., M. J. Finegold, M.D., and J. A. Goss, M.D., BaylorCollege of Medicine, Houston, TX

P60. Stress Fiber Polymerization Is Necessary for Endothe-lial Cell Production of NF-kB-Dependent ICAM-1 Pro-duction during Sepsis. J. Cuschieri, M.D., D. Gourlay, M.D.,I. Garcia, B.S., S. Jelacic, B.S., and R. V. Maier, M.D., Harbor-view Medical Center, Seattle, WA

61. Murine Retroviral Transcripts Are Transiently Up-Regulated in Multiple Organs after Burn Injury. K. Cho,Ph.D., and D. G. Greenhalgh, M.D., Shriner’s Hospitals forChildren–Northern California, Sacramento, CA

62. Heat Shock Inhibits NF-kB Activation in a Transient andDose-Dependent Manner. J. A. Johnson, B.S., W. J. Welch,Ph.D., and H. W. Harris, M.D., UCSF, San Francisco, CA

63. Cytokines Increase CRE Binding in Cultured Rat Hepa-tocytes. B. Zhang, Ph.D., S. Liu, M.D., W. H. Walker, Ph.D.,and B. G. Harbrecht, M.D., University of Pittsburgh, Pitts-burgh, PA

64. Cross-Tolerance between LPS and IL-1b in Mononu-clear Cells. D. M. Gourlay, M.D., J. Cuschiere, M.D., I. Gar-cia, B.A., S. Jelacic, B.S., and R. V. Maier, M.D., University ofWashington, Seattle, WA

65. Quantitative Analysis of Digital Images of Kidney Tis-sue Damage after Septic Shock with and without5-Lipoxygenase Inhibitor. M. Goldenberg, M.D., K. M.Schuster, M.D., J. Van Tran, B.S., and G. J. Slotman, M.D.,Cooper Hospital, RWJMS, Camden, NJ

66. Chylomicrons Inhibit Hepatic NO Production. F. B.Kasravi, M.D., and H. W. Harris, M.D., UCSF, San Fran-cisco, CA

67. Burn-Induced Thymic Apoptosis Corresponds with Al-tered TGF-b1 and Smad 2/3 Expression. K. G. Hobson, M.D.,K. Cho, Ph.D., L. K. Adamson, B.S., and D. G. Greenhalgh, M.D.,University of California Davis Medical Center, Sacramento, CA

68. Bacterial Superantigen Enhances Wound Healing inNormal Mice. B. Manning, M. R. Kell, D. C. Winter, W. O.

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Kirwan, and H. P. Redmond, Department of Academic Sur-gery, Cork University Hospital, Cork, Ireland