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9/17/2013 1 Assessment and Intervention of Opioid Induced Respiratory Depression Using the “POSS” Ann Quinlan-Colwell, PhD, RNC, DAAPM Conflict of Interest Disclosure Conflicts of Interest for author is: NONE A conflict of interest is a particular financial or non-financial circumstance that might compromise, or appear to compromise, professional judgment. Anything that fits this should be included. Examples are owning stock in a company whose product is being evaluated, being a consultant or employee of a company whose product is being evaluated, etc. Taken in part from “On Being a Scientist: Responsible Conduct in Research”. National Academies Press. 1995. Objectives The participant will be able to: describe and explain the POSS describe and explain two ways the POSS can improve patient safety explain how to incorporate the POSS in routine practice list three benefits of the POSS

Assessment and Intervention of Opioid Induced Respiratory ... · • Specific to opioid-induced sedation • High reliability (Chronbach’s alpha >.90) • Clear and simple to use

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Page 1: Assessment and Intervention of Opioid Induced Respiratory ... · • Specific to opioid-induced sedation • High reliability (Chronbach’s alpha >.90) • Clear and simple to use

9/17/2013

1

Assessment and Interventionof

Opioid Induced Respiratory Depression

Using the “POSS”

Ann Quinlan-Colwell,

PhD, RNC, DAAPM

Conflict of Interest Disclosure

• Conflicts of Interest for author is:NONE

A conflict of interest is a particular financial or non-financial circumstance that might compromise, or appear to compromise, professional judgment. Anything that fits this should be included. Examples are owning stock in a company whose product is being evaluated, being a consultant or employee of a company whose product is being evaluated, etc.

– Taken in part from “On Being a Scientist: Responsible Conduct in Research”. National Academies Press. 1995.

Objectives

The participant will be able to:

• describe and explain the POSS

• describe and explain two ways the POSS can improve patient safety

• explain how to incorporate the POSS in routine practice

• list three benefits of the POSS

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The New Hanover Regional Medical Center Journey

Purposes of the Journey

• Insure Safety of all patients

• NHRMC has zero tolerance for Opioid Induced Respiratory Depression (OIRD)

• Satisfy JC requirements

• Adopt a user friendly tool to improve assessment of and intervention for patients at risk of OIRD

• Educate nurses how to use and document this assessment tool

The Beginning

• Commit to patient safety as priority

• Literature review

• Identified Pasero Opioid Sedation Scale as tool for:– Assessment

– documentation

• Presented to Clinical Claims Committee

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Illness – Trauma - Surgery

NSAIDS

Pain

Adjuvants

LocalAnesthetics

Acetaminophen

Opioids

Side Effects

Like all medications Opioids have side effects.

Opioids Work through the Central Nervous System

Common Opioid Side Effects

• Nausea and vomiting

• Pruritus

• Constipation

• Sedation

• Respiratory Distress/Depression

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Respiratory Depression• Characterized by:

– Less than 8 to 12 breaths per minute– Reduced oxygen saturation– Altered arterial CO2 tension– Cyanosis– Periodic apnea– Drowsiness, sedation

• Danger is progression to Respiratory Arrest

Respiratory Depression

• A “vicious cycle”

• Opioid Induced Respiratory Distress occurs due to:

– a lowered carbon dioxide (CO2) drive

– Blunting of chemoreceptor response to oxygen & CO2

– Prolonged exhalation

– Suppression of depth of respirations

– Impaired gas exchange

Clinical Challenges

• Early identification of patients at risk for developing respiratory compromise

• Appropriate assessment for sedation

• Identify sedation that is advancing

• Early intervention to prevent respiratory arrest

• Reasonable documentation

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Increased Risk for OIRD

• First 24 post operative hours

• Untreated Obstructive Sleep Apnea (OSA)

• Respiratory compromise

• Morbid Obesity

• Certain genotypes

• Elderly

• Opioid Naïve

• Opioid Tolerant with changes in dose or opioid

• Concomitant sedating medications

Early Identification of Respiratory Compromise

• Advancing sedation is the earliest sign of respiratory compromise!

• Identify factors that increase risk of OIRD

• Assess Respiratory Function

– Rate for one full minute

– Character and quality

Limitations of Technology

• Reliability and sensitivity issues of the equipment

• Patient compliance with equipment

• Expense

• Hypoxemia measured by pulse oximetry is a late finding

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Nurse Assessment is the Best Intervention to

Prevent OIRD

Challenges

• How to describe the level of sedation that is assessed so that others understand what was assessed?

• How to document the level of sedation that was assessed so that others understand what was assessed?

• What should be done with the information assessed?

Literature Review Search

• RASS

• Ramsay Sedation Scale

• POSS

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Pasero Opioid-Induced Sedation

Scale

(POSS)

The POSSLevel State Dosing Guidance

S Sleepy, easy to arouse

Acceptable; no action necessary; may increase opioid dose if needed.

1 Awake and alert Acceptable; no action necessary; may increase opioid dose if needed.

2 Slightly drowsy, easily aroused

Acceptable; no action necessary; may increase opioid dose if needed.

3 Frequently drowsy

Unacceptable; decrease opioid dose 25%-50% or notify primary MD or anesthesiologist for orders; administer a non-sedating, opioid sparing nonopioid such as acetaminophen or a NSAID; monitoring respiratory status & sedation until level is less than 3 & respiratory status is satisfactory.

4 Somnolent; minimal or no response to physical stimuli

Unacceptable; stop opioid; consider administering naloxone; notify primary MD or anesthesiologist; monitor respiratory status and sedation level closely until sedation level is less than 3 and respiratory status is satisfactory.

Adapted from Sedation scale developed by C. Pasero in 1990; copyright 1994, C. Pasero; Published originally in Pasero, C. (1994) Acute Pain Service: Policy & Procedure Guideline Manual.

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Benefits of POSS

• Specific to opioid-induced sedation

• High reliability (Chronbach’s alpha >.90)

• Clear and simple to use

• No extra time required to assess

• Provides an agreed upon number for ease of documentation

• Provides established guidance for nursing intervention

• Satisfies JC mock survey recommendation

When to Use the POSS

• With every assessment and re-assessment for pain, assess sedation in the person who received opioid analgesia

• Utilize the “Dosing Guidelines” prior to administering additional opioids

• Document in HED, the sedation level using the appropriate letter (S) or number (1, 2, 3, or 4)

Benefits for Patient Safety

• Guidance for safe administration of opioids

• Criteria for using range orders

• Tool to increase patient safety after opioid administration

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More Benefits of Using POSS

• Component of Patient Education

• Tool to improve consistency of documentation

• Tool to document patient status

Introducing The POSS

Incorporating the POSS in Routine Practice

• Education

• Incorporate into EMR

• Audit use

• Incorporate into EPIC

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Educating About The POSS

• Staff meetings and huddles

• Computer Based Learning Module

• Handouts

• New Nurse Orientation

• Staff meetings and huddles

Monitoring Use of the POSS

• Weekly Audits

• Soliciting feedback

TJC Sentinel Alert on Opioids

• “… most serious (adverse) effect being respiratory depression, which is generally preceded by sedation.”

• “the potential for opioid-induced respiratory depression should always be considered”

• 29% of opioid AE were related to improper monitoring

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Change to

EPIC

Auditing Documentation in EPIC

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Improving Documentation

Adjusting in Epic

Improving in Epic

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The Best of Epic

Benefits of Using The POSS

• Encourage routine assessment of sedation

• Easy documentation of sedation

• One criteria for Range Orders

• Improve patient safety

• Satisfy TJC requirements

• Facilitates communication

Remember:

Sedation always

occurs before

respiratory depression!

If a person is sedated as a result of an

opioid, assess respiratory status and

intervene according to the POSS guide.

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References• American Society of Anesthesiologists Task Force. (2009). Practice Guidelines for the prevention,

detection, and management of respiratory depression associated with neuraxial opioid administration. Anesthesiology, 110, 218-230.

• Cronrath, P., et al. (2011). PCA oversedation: Application of healthcare failure mode effect analysis (HFMEA™). Nurse Economics, 2011, 79-87.

• McCaffery, M. & Pasero, C. (1999). Pain: clinical manual (2nd Ed). St. Louis: Mosby.

• Nisbet, A. T. & Mooney-Cotter, F. (2009). Comparison of selected sedation scales for reporting opioid-induced sedation assessment. Pain Management Nursing, 10, 154-164.

• Pasero, C. & McCaffery, M. (2011). Pain assessment and pharmacologic management. St. Louis: Mosby Elsevier.

• Pasero, C. & McCaffery, M. (2002). Monitoring sedation: It’s the key to preventing opioid-induced respiratory depression. American Journal of Nursing, 102 (2), 67-69.

• Pasero, C. (1994). Acute pain management service: Policy & procedure guideline manual. Los Angeles: Academy Medical Systems.

• Smith, L. H. (2007). Opioid safety: is your patient at risk for respiratory depression? Clinical Journal of Oncology Nursing, 11, 293-296.

• Young-McCaughan, S. & Miaskowski, C. (2001). Definition of and mechanism of opioid-induced sedation. Pain Management Nursing, 2, 84-97.

Ann Quinlan-Colwell, PhD, RNCPain Management CNS

[email protected]