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Assessing the Outcome of Multiple- ligament Knee Reconstruction Using Gait Analysis 1 Corey Scholes PhD, 1 Brett Fritsch FRACS 1 , Joe Lynch MSc, 1,2 Jack Batchen Beng, 1 Milad Ebrahimi BEng, 1 Myles Coolican FRACS, 3 Richard Smith PhD, 1 David Parker FRACS 1 Sydney Orthopaedic Research Institute, Chatswood, NSW 2 School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney 3 Faculty of Health Sciences, University of Sydney

Assessing the Outcome of Multiple-ligament Knee Reconstruction Using Gait Analysis 1 Corey Scholes PhD, 1 Brett Fritsch FRACS 1, Joe Lynch MSc, 1,2 Jack

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Lower Limb Coordination in Early Stance Following Multiple Ligament Knee Reconstruction

Assessing the Outcome of Multiple-ligament Knee Reconstruction Using Gait Analysis1Corey Scholes PhD, 1Brett Fritsch FRACS1, Joe Lynch MSc, 1,2Jack Batchen Beng, 1Milad Ebrahimi BEng, 1Myles Coolican FRACS, 3Richard Smith PhD, 1David Parker FRACS

1Sydney Orthopaedic Research Institute, Chatswood, NSW2School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney3Faculty of Health Sciences, University of Sydney

Sydney Orthopaedic Research InstituteDr Joe Costa (FRCSC), Laurant Kang, Amy Brierley BEngStudy participants

University of SydneyRay Patton (Biomechanics Laboratory)

FundingRoyal Australasian College of Surgeons Brendan Dooley-Gordon Trinca Trauma ScholarshipFriends of Mater Hospital FoundationAcknowledgements

None of the authors have received any payment or consideration from any source for the conduct of this study.

Sydney Orthopaedic Research Institute has received fellowship/study funding from;Smith & Nephew;Global OrthopaedicArthritis AustraliaRoyal Australasian College of SurgeonsFriends of Mater Hospital FoundationDeclaration of Interest

IntroductionAt least 2 of 4 major ligaments torn

Usually high velocity trauma

Associated injuries commonReduced long-term joint function

IntroductionLimited information on functional outcomeCan reconstruction restore normal kinematics?Altered kinematicsIncreased joint loadingIncreased risk of OAWeight Acceptance (Ratcliffe et al 1997, Whittle et al 1999)Knee angle determines load distribution Peak forcesRelated to shock attenuation

Database (N = 163); Invited (N = 30); Agreed (N = 16)

Controls matched within 10% age, weight, heightPatient SampleMLKRControlP-valueAge at F/U (yrs)43.2 + 13.541.5 + 14.50.68Height (cm)172.1 + 11.1174.7 + 10.30.47Weight (kg)78.0 + 16.776.8 + 14.70.79BMI26.1 + 3.824.95 + 2.70.38Ave F/U (yrs)4.7+3.5-

(0-20%)

6Injury PatternsLigamentClassificationMeniscal TreatmentAssociated Injuries1ACL/PLCCLPMMx2ACL/MCL/PARTIAL PCLBMPelvic Fracture3ACL/PCL/MCLBM4PCL/MCLCM5PCL/LCL/PLCCL-Open Patella Fracture-Non Displaced Lateral Femoral Condyle-Fracture Right Ankle6ACL/PCL/MCLCM-Tibial Plateau Fracture7ACL/MCLCM8PCL/LCL/PLCBL-Fracture Base Of Skull9ACL/PCL/LCL/PLCBLMMR10PCL/PLCCL11ACL/LCL/PLCCM-CPN Injury With Foot Drop12ACL/PCL/MCL/PMCBM-No Distal Pulse at Operation13ACL/PCL/MCL/PMCBMPLMx14ACL/MCLCM15ACL/PCL/LCL/PLCBL16ACL/PCL/MCLBMPLMxDemographic dataAgeGenderSurgery-followup time

Injury dataLigament patternB/CL/M

Outcome dataPassive flexion contractureKT1000 (194N; max)KOOSIKDC

Clinical follow-up

Conducted at the Biomechanics Laboratory, University of Sydney

3D Motion Capture14x Infrared strobing cameras37 reflective markers

Overground walking at self-selected speed

Step descent and turn @90deg

Motion Capture

Discrete Angles and Range of motion3-dimensional angles at0% of stance (foot strike)60% of stance (begin Propulsion)

3-dimensional range of motion0-20% of stance (Weight Acceptance)60-85% of stance (Propulsion)

Vertical ground reaction force10Methods - Spatiotemporal

VariablesDefinitionVelocity (m/s)Stride length / Stride timeCadence (steps/min) Step count / time in minutesStep Length (m)Distance between the proximal end position of the foot at ipsilateral heel strike to the proximal end position of the foot at the consecutive contralateral heel strikeStep Width (m)Distance between the ipsilateral heel strike to the proximal end position of the foot at the next contralateral heel strikeSingle Support time (%)Time between toe-off and heel strike of the contralateral limbInitial Double Support time (%)Time between heel strike of the ipsilateral limb and toe off of the contralateral limbDouble Support time (%)Sum of initial double support times for the left and right limbsStance time (%)Time between heel strike and toe off of the ipsilateral limbNormality and equality of variance checks

GroupPaired t-tests, Kruskal-Wallis ANOVA (Dunn-Sidak post-hoc comparisons) performed where appropriate

Single subject pair matched comparisonsProportion (%) of patients with sig difference to matched control for each measure

Statistical analysisAre differences in knee kinematics and spatiotemporal characteristics related to clinical symptoms ?PredictorsAgeGenderSurgery-followup delayLigament patternB/CL/MPassive flexion contractureKT1000 (194N; max)KOOSIKDC

Output variablesVelocityStep lengthStep widthCadenceStance durationDouble/single support durationInitial double support durationPartial Least Squares Regression

A regression analysis to look for strength of association between factors13Mean (+95%CI) for MLKI patient responses to IKDC questionnaire and KOOS subscales with solid line denoting mean for healthy controls. Clinical Results

Results - Subjective Scores

Group comparisons -walkingSignificantly internal tibial rotation during propulsion between reconstructed and control knees

Group comparisons - Spatiotemporal Mean+95%CI

P-ValueMLKIControlVelocity (m/s)1.49+0.061.59+0.060.04Step Length (m)0.73+0.020.78+0.02