Click here to load reader

Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

Download PPT Report

Upload
cecil-heath
View
214
Download
0

Embed Size (px)

DESCRIPTION

How Artificial Skin is Made  Skin is usually donated by other donors.  Fibroblasts are removed from the donated skin and are frozen until they are needed.  The fibroblasts are placed on a polymeric mesh scaffolding, gather oxygen, and grow new cells.  The cells are then transferred to a culture system.

Citation preview

Artificial Skin

By: Raymond Litteaur

History of Burns

Before artificial skin was developed, burns covering 50% of the body were considered to be fatal.

In 2000, artificial skin cut death rates in people with over 70% burns from 100% to 40%.

Skin is the body’s largest organs and protects us from physical damage, disease, and controls our body’s temperature.

Page 3: Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

How Artificial Skin is Made

Skin is usually donated by other donors.

Fibroblasts are removed from the donated skin and are frozen until they are needed.

The fibroblasts are placed on a polymeric mesh scaffolding, gather oxygen, and grow new cells.

The cells are then transferred to a culture system.

Page 4: Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

Artificial Skin cont.

After 4 weeks the polymer mesh dissolves and leaves behind a new layer of dermal skin.

When the growth cycle is completed, they add more nutrients. Keratinocytes are added to the collagen and are exposed to air to

form epidermal layers. The skin is now completed and is stored in sterile contains until

ready to use.

Page 5: Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

How Artificial Skin is Used

Artificial skin is already being used for burn victims and soon will be available for other skin disorders.

The skin is not used for a permanent replacement, but to temporary cover the skin until your skin can grow back naturally.

Page 6: Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

The Future

Because skin is an organ, there are many similarities between skin and other organs.

There is hope to regenerate joints, ears, noses, livers, kidneys, and hearts.

Page 7: Artificial Skin By: Raymond Litteaur. History of Burns Before artificial skin was developed, burns covering 50% of the body were considered to be fatal

References

GAO Report. 31 May 2005. GAO-05-759T. “Advanced Technology Program: Inherent Factors in Selection Process Are Likely to Limit Identification of Similar Research” <http://www.gao.gov/htext/d05759t.html>

McNulty, Mary F. “Artificial Skin”. <http://www.gale-edit.com/products/volumes/skin.htm> Smith, Carol. 23 Feb. 2001. “Artificial skin offers genuine hope” <

http://seattlepi.nwsource.com/local/burn231.shtml> T.J. Samson Community Hospital. 1 Jan 2005. “Artificial Skin” <http://tjsamson.client.web-

health.com/web-health/topics/GeneralHealth/generalhealthsub/generalhealth/skin&hair&nails/AGING&COSMETIC/skin_artificial.html>

Pictures: http://www.devicelink.com/mddi/archive/98/05/018.html http://www.biomed.metu.edu.tr/courses/term_papers/artificial%20skin_cinar.htm

http://www.gao.gov/htext/d05759t.html

http://www.gale-edit.com/products/volumes/skin.htm

http://seattlepi.nwsource.com/local/burn231.shtml