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Injury to lining of blood vessel exposes collagen fibers.

1.

Platelets become sticky and flatten against torn wall.

2.

Platelets begin to release chemicals that make other

nearby platelets sticky.

3.

Prothrombin activator released from damaged cells

4.

Prothrombin activator convertsprothrombin to thrombin.

5.

Thrombin catalyzes the joining of fibrinogen molecules into a

fibrin mesh.

6.

Contraction of proteins released by platelets pulls

edges of wound closer together.

7.

Platelet-derived growth factor released by platelets

stimulates the repair of the damaged lining of the blood

vessel.

8.

Fibrinolysis removes clot.

9.