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Aromatics Psychodynamics In Skin Care Beyond the topical approach to skin care in Aromatherapy Danielle Sade Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

Aromatics Psychodynamics In Skin Care

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Aromatics Psychodynamics In Skin Care Beyond the topical approach to skin care in Aromatherapy

Danielle Sade

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

1. “Bringing awareness of the emotional and psychological impact on skin condition. 2. Using essential inhalations to lower Cortisol in the system to assist in relieving inflammation. 3. Learn about a selection of essential oils that have been proven to lower Cortisol in the blood

Major outcomes

THE SKIN u  Provides a protective barrier

u  Prevents loss of moisture

u  Reduces harmful effects of UV radiation

u  Helps regulate temperature

u  Takes part in the immune response

u  Synthesis Hormone Vitamin D

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

The skin is a complex neurological system in the sensory structures!

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

It

“FEELS” Peripheral Stimulation; such as pressure, vibrations, pain, cold and heat.

& Internal Stimulation, the skin feels pleasure, love, fear, sadness and stress through the

secretions of different hormones from our neuroendocrine system!

“The skin also has the capacity to

smell!

Olfactory Receptors have been

identified in the epidermal skin layers and other

tissues!(Hatt et.al)

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

The human perception of skin has a lineage that goes back

thousands of years!

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

We are living in a world that puts a lot of emphasis on youthful, flawless, clear, radiant and glowing skin!

Creating an illusion on the reality of what skin should look like!

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

‘Tzarath’ was referred to Biblical Leprosy ” This term referred to SKIN FLAWS and RITULISTIC IMPURITIES –

Biblical Leprosy was considered to be a powerful symbol of sin! (Grzybowski et.al) .

\

In the late 17th century Salem Village Massachusetts were tried for the crime of practicing witchcraft. The part of the evidence were skin lesions, birthmarks and moles.– when theses were found on the body they were accused of having a pact with the devil. “Described as the Devils mark!”(Flotte et.al)

(photography public Domain, https://en.wikipedia.org/w/index.php?curid=15322490

“Adam and Eve had bodies clothed with “Garments of Light.”

Genesis

When they sinned they lost their light and were

embarrassed and humiliated and were forced to cloth

themselves.

Peter Paul Rubens Creative commons

Chronic and long term skin conditions have

psychological impact on ones quality of life.

The longer the duration of living with the

condition, the more likely there will be poor emotional functioning

and lower energy levels. .”(Parana et.al)

In 2013 “One in four individuals of all ages were seen by a

physician for at least 1 skin condition.”

Acne

Depression

Wrinkles

Psoriasis

Rosacea

Skin cancer

isolation

Alopecia

Warts

Low self esteem

Seborrhea

Anxiety

Yoga

Guided Visualization

Mindfulness

Bio-Feedback

Cognitive Therapy

Healthy lifestyle approaches (Nutrition & Exercise)

Dermatologist are beginning to integrate mind & body approach in a new field of medicine

“Psycho-Dermatology”

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

Aromatic Psychodynamics

Can equip the therapist with an integrative tool to

provide comfort and well-being for those experiencing

skin conditions!

Through inhalation of natural aromatic essential oils, shifting the way the individual feels inside &

out!

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

The Road Map To Feelings!

Experience ! Perception

Positive or negative!

Mind

Reactions!

Thoughts are trigger evolving

into feelings.

Autonomic System gets

involved

Recruiting Sympathetic or

Para-sympathetic response

Effecting the Skin

The skin feels what you feel!

Aromatic Psycho-Dynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

Geraniol

Linalool

Limonene Alpha pinene

Olfactory Bulb

Transmits signals to the

brain

Olfaction has a unique relationship on how we feel!

Aromatic Vapors enter into the nose towards the

olfactory epithelium!

Passes through cribriform bone into the olfactory Bulb

Projecting into the involuntary limbic

system

Hypothalamus Maintain & Controls

body functions

Amygdala Emotions

Neo Cortex Cognitive

recognition

Hippocampus Memory

Pituitary Gland

ANS Sympathetic &

parasympathetic

Adrenal Glands

Release ACTH

Release Cortisol

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

HYPOTHALMUS – PITUITARY-ADRENAL AXSIS (HPA)

Produces elevated level

Corticotrophin releasing hormone (CRH) & Adrenocorticotropic hormone (ACTH)

Signals the Adrenals to secrete

And other inflammatory neuropeptides

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

ACTH

Substance P

CRH

High levels of ACTH & CRH in the skin can lead to slower healing recovery in wounds and skin conditions!

Some studies to observe!

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

Why Use of Aromatic Psychodynamics

Studies have proven that inhalation of certain essential oils and their components can influence.

1.  Neurophysiological pathways (Physiology of the Nervous system)

2.  The sympathetic nervous system (Involves the fight & flight response)

3.  The Para-sympathetic nervous system (involves the rest & digest response)

Essential Oils can be Psychoactive and Cortisol inhibiting

Cortisol Inhibiting Essential Oils

v  Lavender – Relieves Anxiety, Sedating,

v  Neroli –Relieves Anxiety, antidepressant

v  Citrus Oils – Dopaminergic, antidepressant, Relieves Anxiety

v  Rose – Relieves Anxiety, Antidepressant

v  Clary Sage – Sedating, Relieves Anxiety

v  Sandalwood – Relieves Anxiety, sedating

v  Patchouli – Relieves Anxiety

Cortisol Inhibiting Constituents

v  d-limonene – Dopaminergic, antidepressant, Relieves Anxiety

v  Linalool – Relieves Anxiety, Sedating, analgesic

v  Patchouli Alcohol –Relieves Anxiety

v  Alpha-Sanatol - Relieves Anxiety, Sedative

Chronic Skin Inflammation

PSORIASIS

Depression, Anxiety, Insomnia

Isolation, Phobias

PSYCHOLOGICAL

IMPACT

Increase in Cortisol

Increase in Substances

HPA

Bergamot

Lemon

Neroli

Inhalation/Diffuser

Neroli

Sandalwood

Patchouli

Sandalwood Bath 1% in dispersant or

oils

Neroli,

Creams, lotions, Gels, Massage Oils

Inflammation

Excessive proliferation of skin cells

Pain, Itching, Sensitive, prone to infection and irritation.

PHYSICAL IMPACT

Chronic & relapsing inflammatory skin condition related to

eczema & itch

Atopic Dermatitis

Frustration, Tension, Anxiety, Depression

PSYCHOLOGICAL IMPACT

Increase in Cortisol

High levels of substance P

HPA

Neroli, Bergamot

Inhalations

Inflammation

Raw dry cracked skin, burning Pain, Itching

PHYSICAL IMPACT

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

Common skin conditions can have an early onset in puberty

and be related to hormonal imbalances during adulthood

ACNE

Inferior, Low self esteem, Unmotivated, Depression

PSYCHOLOGICAL IMPACT

CRH found in Sebocytes

High levels of Substance P in sebaceous glands and around

acne lesions

HPA

Lemon

Bergamot

Neroli

Inhalations 5-10 drops

Bergamot FCF

Patchouli

1% Cleansers - Toners

Bergamot FCF

Sandalwood

Patchouli

1%Gels & moisturizers

Red inflamed elevated lesions Inflammation

Excessive sebum production. Painful and Sensitive

PHYSICAL IMPACT

A natural genetic process that influences chemical process

that occurs from birth.

Aging Skin

Grief, Discrimination, Social anxiety and isolation

PSYCHOLOGICAL IMPACT

UV radiation, smoking, air pollution induces CRH,ACTH, cortisol.

High levels of Cortisol causes sleep deprivation, suppression of hyaluronic

synthase and reduction in collagen mass.

HPA

Rose Otto Neroli

Lavender, Sandalwood, Patchouli, Clary Sage

Inhalations

Rose Otto, Neroli, Lavender, Sandalwood, Patchouli,

Clary Sage

Baths

Rose Otto, Neroli, Lavender, Sandalwood, Patchouli,

Clary Sage

Creams, Lotions, Oils

Reduced elasticity, Fine lines (Wrinkles) and un-even skin

tone.

PHYSICAL IMPACT

Aromatic Psychodynamics is a trademark of Healing Fragrances School of Aromatherapy and Danielle Sade

Aromatic Psychodynamics of Bergamot FCF in skin care Citrus bergamia

Bitter sweet citrus aroma that allows a frequency of light to move inwards. Enlightening the

light within – resonating with harmony that we posses.

Linyal acetate

38%

d-Limonene 24%

Linalool 20%

Y-Terpinene 9%

B-Pinine 9%

Psychoactivity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant Balancing

Anti-bacterial Anti-fungal Sedative

Acne Olfaction & Topical Up to 1% dilution

Cold Sores Olfaction & Topical 1% dilution

Chronic Skin Conditions

Mostly Olfaction & Carrier oils 0.05%

Fungal infections

Topical Up to 3% dilution

Wounds Olfaction – to help reduce stress & anxiety

Inhalation of bergamot has been recognized as reducing stress and anxiety. Recent studies have demonstrated that the essential oil vaporized and inhaled can significantly reduce cortisol levels via the olfactory bulb. A secondary pathway can be described as a time released of the essential oils is absorbed through the respiratory tract then transported to the nervous system via blood circulation recruiting the Para sympathetic state. (Wantabe et, al 2015)

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

Aromatic Psychodynamics of Neroli in skin care Citrus aurantium va amara (orange blossom)

Vibrant soft sweet hallow floral fragrance Encourages absolute knowing of direction that with calm and peace

Linalool 51%

Linalyl acetate

8%

B-Ocimene 5%

a Terpineol

6%

b-pinene

5%

Nerolidol 3%

Geraniol 6%

Farnesol 3%

Neryl acetate

2%

Myrcene 2%

Supporting Constituent

s 9%

Psychoactivity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant Balancing

Anti-bacterial Anti-inflammatory Sedative

Acne Olfaction & Topical Up to 1% dilution

Chronic Skin Conditions

Mostly Olfaction & Carrier oils 0.05%

Aging Skin Topical up to 1% olfaction

Wounds Olfaction – to help reduce stress & anxiety

Inhalation of Neroli was found to reduce blood pressure and found to decrease cortisol levels having a calming effect on the nervous system.(Choi 2014) 

Aromatic Psychodynamics of Clary Sage in skin care Salvia sclarea (French)

Warm, light musky fragrance that captivates our existence with mellow kind tranquil, clarity elevating content in our heart. Revitalizing an inner force to move with our time.

Linalyl acetate, 55

Linalool, 15

Beta-caryophyll

ene, 5

Supporting constiuents,

25

Psychoactivity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant

Anti-bacterial Anti-inflammatory Sedative

Chronic Skin Conditions

Olfaction

Aging Skin Topical up to 1% olfaction

Wounds Olfaction – to help reduce stress & anxiety

1 ml of 5 minute inhalation of clary sage essential oil were administrated to a group of menopausal in depressed states. Resulting in a significant reduction of cortisol levels in blood plasma. Concluding that clary sage is anti-depressant (Lyung Bok Lee et, al 2014)

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

Aromatic Psychodynamics of Rose Otto in skin care

Rosa damascena

Voluptuous soft feminine aroma which inspires the angelic realms to flow through the heart. Awakening our love that is in the chambers of our heart. Opening the doors to devotion,

compassion, purity contentment and inner vitality.

Citronellol 40%

Geraniol 20%

Nerol 7%

Farnesol 2%

Phenylethyl alcohol

2%

Methyl eugenol

2%

Supporting trace

constituents 26%

b-ionone 1%

Psychoactivity Therapeutics

Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant

Anti-bacterial Anti-fungal Anti-Inflammatory Humectant Balancing

Acne Olfaction & Topical Up to 1% dilution

Aging Skin Olfaction & Topical 1% dilution

Chronic Skin Conditions

Mostly Olfaction & Carrier oils 0.05%

Fungal infections

Topical Up to 3% dilution

Wounds Olfaction – to help reduce stress & anxiety, prevents moisture loss

Studies on 43 healthy individuals have demonstrated that through inhalation of rose Otto a reduction of sympathetic activity and levels of adrenalin were found to have decreased. (Sugawara et,al 1998) Inhalation of rose otto inhibited due to of chronic stress through HPA decrease of trans epidermal water loss, decrease of cortisol in salivary during times of chronic stress. (Fukada 3t, al 2011)

Aromatic Psychodynamics of Lavender in skin care

Lavendula Angustifolia The fresh bright herbaceous floral fragrance embodies a protective feeling that nurtures our thoughts with comfort. Providing us with heavenly energies to support our needs . Encouraging compassion, vitality,

clarity, comfort and acceptance to create an emotional balance.

Linalool 37%

Linayl acetate

42%

Supporting trace

constituents 21%

Major constituents in Lavender

Psychoactivity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant Uplifting/Calming Sedative

Anti-bacterial Anti-fungal Anti-Inflammatory

Acne Olfaction & Topical Up to 1% dilution

Aging Skin Olfaction & Topical 1% dilution

Chronic Skin Conditions

Mostly Olfaction & Carrier oils 0.05%

Fungal infections

Topical Up to 3% dilution

Wounds Olfaction – to help reduce stress & anxiety

Inhalations of lavender in mice decreased aggression and increased social interaction was observed (da Silva et.al., 2008). The major constituent in lavender linalool presents to be readily absorbs through the skin lowers. Inhalation of linalool was found to increase Dopamine and Noradrenalin neurotransmitters (Mimaki et.al) that are fundamental to a state of balanced emotional equilibrium. (Sade) Reduces swelling and inflammation (Peana et.al) and has antimicrobial properties (Herman et.al).

Aromatic Psychodynamics of Lemon in skin care Citrus limon

A radiant fresh citrus aroma which enlightens motivation towards vitality.

Lemonene 67%

Beta Pinene 10%

y terpenene 10%

Myrcene 2%

Trace consttituents

11%

Psychoactivity Therapeutics

Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant

Anti-bacterial Stimulant

Acne Olfaction & topical up to 1% Photo-toxic

Chronic Skin Conditions

Olfaction for depression and motivating

Wounds Olfaction – to help reduce stress, depression & anxiety

Lemon specifically was noted to increase the turn over of dopamine and serotonin after inhalation in mice. (Komiya et al., 2006)  

Aromatic Psychodynamics of Sandalwood in skin care

Santalum austrocaledonicum Rich balsamic earth aroma that reaches the cosmic world between heaven and earth. Bring for the

understanding all is one and we are part of one. Creating sensitivity, serenity, harmony wisdom and unity.

cis-B-santalen

e, 2

alpha-santalol,

28

epi-B-santalol,

4

cis-B-sanatolol

, 16 lanceol, 5

nuciferol, 9

alpha-bergamo

tol, 7

Psych activity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant Balancing

Anti-bacterial Anti-fungal Sedative

Acne Olfaction & Topical Up to 1% dilution

Aging skin Olfaction & Topical 1% dilution

Chronic Skin Conditions

Mostly Olfaction & Carrier oils 0.05%

Wounds Olfaction – to help reduce stress & anxiety

Alpha-Sanatol a major constituent in in Australian sandalwood was able to permeate into the skin and lower blood pressure and calm the nervous system down. (Heuberger E et.al) Both alpha and beta santalol were also found to be anti-inflammatory (Sharma et.al). In another study it was found that alpha-santalol inhibited and was cytoxic to various skin cancers. (Kaur M.)

  “Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

Aromatic Psychodynamics of Patchouli in skin care Pogostemon patchouli

A smoky, herbaceous earthy aroma that brings forth sacredness of space stimulating the idea of knowing and appreciating the deepness within ourselves!

Patchoulol 25%

alpha Bulnesene

15%

alpha Guaine

13%

Seychellene

8%

Alpha Patchoulen

e 9%

Beta Patchoulen

e 7%

Gama Patchoulen

e 8%

Beta caryohyllen

e 4%

Pogostone 3%

Supporting trace

constituents

8%

Psychoactivity Therapeutics Skin Conditions

Type of Applications

Relieves Anxiety Anti-depressant Balancing

Anti-bacterial Anti-fungal Sedative

Acne Olfaction & Topical Up to 1% dilution

Aging skin Olfaction & Topical 1% dilution

Chronic Skin Conditions

Olfaction & Topical Ointment, gels, creams & lotions 0.05%

Fungal infections

Topical Up to 3% dilution

Wounds Topical & Olfaction – to help reduce stress & anxiety

Calming and relax the mind be reducing the sympathetic nervous system activity. (Haze et.al) Active against several bacterial infections, anti-inflammatory, antiviral and biodegradable insecticidal agent. At 12% dilution relieved ulcerative wounds, pressure sores exhibited anti-oxidatve properties and prevented photo aging caused by UV exposure (Swamy M et.al)

Aromatic Psychodynamics is the use of Natural Aromatic Essential oils to shift the way we feel!

References v  Glaser R, Kiecolt-Glaser J, Marucha P, MacCallum R, Laskowski B, Malarkey W. Stress-Related Changes in

Proinflammatory Cytokine Production in Wounds. Archives of General Psychiatry. 1999;56(5):450.

v  2. Chen Y, Lyga J. Brain-Skin Connection: Stress, Inflammation and Skin Aging. Inflammation & Allergy-Drug Targets. 2014;13(3):177-190.

v  3. Shenefelt P, Shenefelt D. Spiritual and religious aspects of skin and skin disorders. Psychology Research and Behavior Management. 2014;:201.

v  4. Pärna E, Aluoja A, Kingo K. Quality of Life and Emotional State in Chronic Skin Disease. Acta Dermato Venereologica. 2015;95(3):312-316.

v  5. Haze S, Sakai K, Gozu Y. Effects of Fragrance Inhalation on Sympathetic Activity in Normal Adults. The Japanese Journal of Pharmacology. 2002;90(3):247-253.

v  6. Altemus M, Rao B, Dhabhar F, Ding W, Granstein R. Stress-Induced Changes in Skin Barrier Function in Healthy Women. Journal of Investigative Dermatology. 2001;117(2):309-317.

v  7. Denda M, Tsuchiya T, Elias P, Feingold K. Stress alters cutaneous permeability barrier homeostasis. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2000;278(2):R367-R372.

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

References 8. Kim I, Kim C, Seong K, Hur M, Lim H, Lee M. Essential Oil Inhalation on Blood Pressure and Salivary Cortisol Levels in Prehypertensive and Hypertensive Subjects. Evidence-Based Complementary and Alternative Medicine. 2012;2012:1-9.

9. Lee M, Lim S, Song J, Kim M, Hur M. The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults: Randomized controlled trial. European Journal of Integrative Medicine. 2017;12:79-86.

10. Choi S, Kang P, Lee H, Seol G. Effects of Inhalation of Essential Oil ofCitrus aurantiumL. var.amaraon Menopausal Symptoms, Stress, and Estrogen in Postmenopausal Women: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2014;2014:1-7.

11. Lee K, Cho E, Kang Y. Changes in 5-hydroxytryptamine and Cortisol Plasma Levels in Menopausal Women After Inhalation of Clary Sage Oil. Phytotherapy Research. 2014;28(12):1897-1897.

12. Fukada M, Kano E, Miyoshi M, Komaki R, Watanabe T. Effect of "Rose Essential Oil" Inhalation on Stress-Induced Skin-Barrier Disruption in Rats and Humans. Chemical Senses. 2011;37(4):347-356.

13. de Sousa D, Silva R, Silva E, Gavioli E. Essential Oils and Their Constituents: An Alternative Source for Novel Antidepressants. Molecules. 2017;22(8):1290.

14. Pärna E, Aluoja A, Kingo K. Quality of Life and Emotional State in Chronic Skin Disease. Acta Dermato Venereologica. 2015;95(3):312-316

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

References 15. Swamy M, Sinniah U. A Comprehensive Review on the Phytochemical Constituents and Pharmacological Activities of Pogostemon cablin Benth.: An Aromatic Medicinal Plant of Industrial Importance. Molecules. 2015;20(5):8521-8547.

16. Ito K, Akahoshi Y, Ito M, Kaneko S. Sedative effects of inhaled essential oil components of traditional fragrance Pogostemon cablin leaves and their structure–activity relationships. 2018.

17. Heuberger E, Hongratanaworakit T, Buchbauer G. East Indian Sandalwood and α-Santalol Odor Increase Physiological and Self-Rated Arousal in Humans. Planta Medica. 2006;72(9):792-800.

18. Sharma M, Levenson C, Bell R, Anderson S, Hudson J, Collins C et al. Suppression of Lipopolysaccharide-stimulated Cytokine/Chemokine Production in Skin Cells by Sandalwood Oils and Purified α-santalol and β-santalol. Phytotherapy Research. 2013;28(6):925-932.

19. Kaur M. Skin cancer chemopreventive agent,  -santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 2004;26(2):369-380.

20. Buchbauer G, Jirovetz L, Jäger W. Aromatherapy: Evidence for Sedative Effects of the Essential Oil of Lavender after Inhalation. Zeitschrift für Naturforschung C. 1991;46(11-12):1067-1072.

21. Yamada K, Mimaki Y, Sashida Y. Effects of Inhaling the Vapor of Lavandula burnatii super-Derived Essential Oil and Linalool on Plasma Adrenocorticotropic Hormone (ACTH), .

“Aromatic Psychodynamics is a trade mark of Healing Fragrances School of Aromatherapy and Danielle Sade”.

References 23. Catecholamine and Gonadotropin Levels in Experimental Menopausal Female Rats. Biological & Pharmaceutical Bulletin. 2005;28(2):378-379.

22. Tisserand R, Young R, Williamson E. Essential oil safety. 2nd ed. Edinburgh [etc.]: Churchill Livingstone/Elsevier; 2014.

23. Sade D. Aromatherapy beauty guide - using the science of carrier & essential oils t. 1st ed. Toronto: Robert Rose;.

24. Sade D. The Practitioners Guide to Aromatherapy (A practitioners guide to Aromatherapy, the study of essential oils and their therapies). 5th ed. Vaughn: Healing Fragrances; 2016.

25. Grzybowski A, Nita M. Leprosy in the Bible. Clinics in Dermatology. 2016;34(1):3-7.

26. Flotte T, Bell D. Dermatopathology in Historical Perspective Karl Holubar, Editor; Role of Skin Lesions in the Salem Witchcraft Trials. The American Journal of Dermatopathology. 1989;11(6):582-587.

Photography: Slides 1,2,4,5,6,7, 8 Creative Commons Royalty Free

Photography: Slides 3,5,7,11,13, 14 I stock Standard License

Diagrams: Danielle Sade 2018