PROFICIENCY TESTING

When to use CAP PT and when other PT survey providers can be used

The Centers for Medicare and Medicaid Services (CMS) regulates all human laboratory testing through the Clinical Laboratory Improvement Amendments (CLIA). CMS has a list of regulated analytes that require enrollment in a CMS-approved proficiency testing (PT) program. In hemostasis, these analytes are PT, APTT, and fibrinogen. New York Department of Health also requires a CMS-approved PT program for the same analytes. The College of American Pathologists (CAP) proficiency survey program is CMS approved. In addition, CAP has a few additional coagulation analytes that require a CAP-approved PT program for laboratories that are CAP-inspected: factor VIII activity, quantitative D-dimer, anticardiolipin IgG/M, and homocysteine. Analytes that require CAP-approved PT programs can be found on the CAP website or can be easily located on your CAP laboratory accreditation program Laboratory Activity Menu and are indicated by a “Y” in the PT Required Column. Laboratories that are not inspected by CAP can use NASCOLA alone for all proficiency except PT, PTT, and fibrinogen. For CAP-inspected laboratories, all analytes that are listed on your CAP Laboratory Activity Menu that have a “Y” in the Alternative Assessment Required column can use NASCOLA alone (or PT provided by CAP or other PT providers). CAP-inspected laboratories cannot use NASCOLA alone for factor VIII activity, quantitative D-dimer, anticardiolipin IgG/M, or homocysteine, as CAP requires CAP proficiency or a CAP-approved program for these analytes. This information can also be found on the NASCOLA website www.nascola.com

Volume 13 | Issue 1

April 2017

NASCOLA Executive Board 2017

President: Dorothy Adcock, MD Esoterix Coagulation

Past president: James Zehnder, MD Stanford University

Vice President: Kristi Smock, MD University of Utah

Secretary: Donna Castellone, MS, MT(ASCP) SH New York Presbyterian, Columbia

Treasurer: Robert C. Gosselin, CLS Emeritus

Members-at-large Jana Gausman, MT(ASCP) Oklahoma City VA

John Francis, PhD Florida Hospital

Nicole Zantek, MD University of Minnesota

Ex-Officio Members 2017

Director, Quality Assessment Program Richard A Marlar, PhD University of New Mexico

Executive Director Elizabeth Plumhoff, MT(ASCP) Mayo Clinic Rochester

Education Liaison William L. Nichols, MD Mayo Clinic Rochester

ECAT Liaison Jana Gausman, MT(ASCP) Oklahoma City VA Medical Center

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EXECUTIVE DIRECTOR NOTES

Greetings! As we enter NASCOLA’s 17th year, there is much to celebrate

and much to anticipate. New NASCOLA officers are the first to assume a

3-year term as mandated by our updated bylaws. Once again, the

executive board consists of highly qualified individuals who have a

passion for the field of hemostasis and thrombosis. Short biographies of

the elected officers are the basis for this newsletter.

NASCOLA continues collaboration with THSNA to promote education and

research, and with ISLH to bring excellent and pertinent presentations to

members through the annual conference. The NASCOLA member base

continues to grow as laboratory leadership discovers the quality and

breadth of proficiency testing material supplied by our ECAT Foundation

partner.

New and longstanding members are encouraged to join a committee of

interest. Contact a NASCOLA committee chair or the executive director

(info@nascola.com ) to learn more.

Subcommittee Chairs and Members:

Heparin-induced thrombocytopenia Kristi Smock, chair Peihong Hsu, Elizabeth Van Cott Factors Nicole Zantek, chair Peihong Hsu, Majed Refaai, Kristi Smock, Elizabeth Van Cott Factor XIII Peihong Hsu, chair Judith Brody, Kristi Smock, Elizabeth Van Cott, Nicole Zantek, Xinmin Zhang Factor VIII Inhibitor Ravij Pruthi, chair Platelet Committee Dong Chen, chair for Dense Granule EM Dong Chen, Sara Israels, Russell Higgins, Elizabeth Van Cott, chairs for Platelet Aggregation Catherine Hayward, honorary co-chair Elizabeth Plumhoff Anti-factor Xa Rita Selby Activated protein C resistance Peihong Hsu and Richard Marlar, co-chairs Protein C Stephen Johnson, chair Jason Baron, Catherine Hayward, Elizabeth Van Cott Protein S Kristi Smock, chair Nahla Heikal, Peihong Hsu, Elizabeth Plumhoff, Elizabeth Van Cott, Nicole Zantek Antithrombin Dong Chen Critical values in Special Coagulation Karen Moffat, Elizabeth Plumhoff, Dorothy Adcock Funk, Catherine Hayward

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PRESIDENT: Dorothy Adcock, MD

Dr. Adcock is the newly elected NASCOLA president. After completing her BS and MD from Michigan State University, she completed her residency in pathology at the University of Colorado Health Sciences Center. She is the medical director of coagulation at Esoterix Coagulation Englewood and has served in this role since 1990. Dr. Adcock has been involved in the field of hemostasis on a national and international basis for the past 20 years. She is chair of the Hematology and Pathology Device Panel for the FDA and is active on national committees for ASCP and CAP including the coagulation resource committee. Dr. Adcock is past chair of the Clinical Laboratory Standards Institute Area Committee on Hematology and has authored a number of CLSI guidelines. She has served as a member of the CAP Coagulation Resource Committee. In her support of NASCOLA, she has served as secretary, treasurer, and vice president. Dr. Adcock lectures often on a national level and has authored over 60 peer-reviewed articles in the area of hemostasis as well as a dozen book chapters.

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VICE PRESIDENT: Kristi J. Smock, MD

Dr. Smock is an associate professor in the Department of Pathology at the University of Utah. She completed her residency and fellowship training at the University of Utah and is board certified in anatomic and clinical pathology and hematopathology. She serves as medical director of the Hemostasis/Thrombosis Laboratory at ARUP Laboratories where she enjoys being involved in all aspects of the laboratory. She is interested in education and serves as the Associate Residency Program Director for the pathology residency program at the University of Utah, director of the rotations in coagulation medicine for residents and fellows in the pathology department, and is actively involved in medical student teaching. Dr. Smock has been a part of the NASCOLA executive board for the past 2 years as a member-at-large. She has also been actively involved in several NASCOLA proficiency testing subcommittees, including serving as chair of the heparin-induced thrombocytopenia and protein S subcommittees and as a member of the factor assays, factor XIII, and activated protein c resistance subcommittees.

SECRETARY: Donna Castellone, MS, MASCP, MT (ASCP), SH

Donna D. Castellone is the QA manager for specialty testing and supervisor, special coagulation and special hematology at New York Presbyterian Hospital- Columbia, New York, New York. Donna has 33 years of clinical laboratory experience and 6 years industry clinical trial experience. She has nearly completed PhD work on standardization of laboratory testing (all but dissertation), and has authored several book chapters and publications, and presented many coagulation lectures. Donna is an adjunct professor at York College and Rutgers University. Most recently, she served on the NASCOLA executive committee as a member at large, and is on the publication and precurriculum committee for ASCP, and the expert committee for hematology for CLSI. Donna's professional memberships include ISTH, ISLH, and ASCP.

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TREASURER: Robert Gosselin, CLS

Robert C. Gosselin, CLS is recently retired from his position as senior specialist in hematology/hemostasis at the University of California, Davis Health System in Sacramento, CA. Mr. Gosselin is a licensed Clinical Laboratory Technologist in California, and certified Specialist by the International Society of Clinical and Applied Hemostasis, Thrombosis and Vascular Medicine. Bob has authored or coauthored over 70 peer-reviewed articles related to coagulation, 2 books chapters, and participated in over 40 national and international speaking engagements. He is a member of the ISLH, NASCOLA, and recently served as member-at-large with NASCOLA. Bob serves as a member for the CLSI consensus committee on hematology, is also a member of the CLSI’s document development committee for von Willebrand assays, an advisor for CLSI’s document development committee for lupus anticoagulant testing, and serves as a reviewer for several journals including the Annals of Pharmacology, Journal of Thrombosis and Haemostasis, Thrombosis and Haemostasis, and the International Journal of Laboratory Hematology.

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MEMBER-AT-LARGE

JOHN FRANCIS, PhD

John Francis, PhD is the Director of the Florida Hospital Center for Thrombosis Research. Originally from the United Kingdom, he joined Florida Hospital from Southampton University Medical School in 1994. Dr. Francis' main research and clinical interests are in the areas of anticoagulant therapy, heparin-induced thrombocytopenia, hemostasis and cancer, hypercoagulability, platelet function and novel approaches to the assessment of patients with hemostatic disorders. An experienced educator, Dr. Francis also holds the title of Professor of Medical Education at the University of Central Florida, College of Medicine.

Dr. Francis is a member of the International Society for Thrombosis and Hemostasis and The American Heart Association. He was the founding editor of the International Journal, Blood Coagulation & Fibrinolysis, served on the editorial board of Thrombosis Research and acts as a reviewer for more than 20 other journals in the field of hemostasis, thrombosis and cardiovascular medicine. He acted as chair of the Region I and II Thrombosis Study Group of the American Heart Association, and was a previous executive committee member NASCOLA.

Dr. Francis acts as a consultant for several pharmaceutical and diagnostics companies, and is a member of the FDA Hematology Devices Panel. He has given over 270 invited lectures, 200 research presentations, and published more than 120 papers in this field.

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MEMBER-AT-LARGE

JANA GAUSMAN, MT(ASCP)

Jana Gausman, MT is the supervisor of Hematology, Immunology, and Coagulation Laboratories at the Oklahoma City Veteran Affairs Medical Center. She received her BS in medical technology from East Central University in Ada, Oklahoma, after which she did clinical laboratory work and research at the University of Oklahoma and the Oklahoma City Veteran Affairs Medical Center. For the past 16 years, Jana has been the supervisor of hematology, immunology, and coagulation laboratories at the Oklahoma City Veteran Affairs Medical Center.

Jana serves NASCOLA as the ECAT liaison and as the contact for members with questions about the proficiency testing program.

MEMBER-AT-LARGE

NICOLE ZANTEK, MD, PhD

Dr. Zantek is an Associate Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota, Minneapolis, MN where she also serves as Medical Director of the Special Coagulation Laboratory and is attending physician in the Division of Transfusion Medicine. Dr. Zantek received a Bachelor of Arts degree from Concordia College in Moorhead, MN and as a Howard Hughes Medical Institute predoctoral fellow, earned her PhD from Purdue University. She earned her medical degree from Georgetown University School of Medicine and remained for a residency in Anatomic Pathology and Clinical Pathology at Georgetown University Hospital. Dr. Zantek then traveled to the University of Minnesota and completed fellowship training in Transfusion Medicine/Blood Banking. Her research interests include quality in hemostasis testing, understanding the influence of extracorporeal circuits on hemostasis, and pediatric transfusion medicine.

Dr. Zantek believes that a critical area for NASCOLA to focus on is promoting collaborative research activities among its members. Development of a network of investigators and laboratories that have diverse areas of expertise and availability of test methods would expand the ability of researchers to connect and advance the field.

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MEMBERSHIP

New Members in 2017

• Dartmouth Hitchcock Medical Center • Royal Columbian Hospital • Shire • Surrey Memorial Hospital • University of California - Irvine Medical Center

5-Year Associate Members

• Affinity Biologicals, Inc • Aniara • DiaPharma • George King Bio-Medical, Inc. • Instrumentation Laboratory • Precision Biologic • r2 Diagnostics • Sekisui Diagnostics, LLC • Siemens Healthcare Diagnostics • Stago

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NASCOLA PUBLICATIONS

1. Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EM. Protein S testing in patients with protein S deficiency, factor V Leiden, and rivaroxaban by North American Specialized Coagulation Laboratories. Thromb Haemost 2016 Jul 4;116(1):50-57

2. Practical Considerations in the Evaluation of an Isolated, Elevated APTT. Adcock-Funk D, Gosselin R. Pearls in Laboratory Medicine. American Association for Clinical Chemistry (AACC), February 2014

3. Anti-Xa: A Versatile and Quantitative Anticoagulant Drug Assay. Riley P. Pearls in Laboratory Medicine. American Association for Clinical Chemistry (AACC), 2014

4. Zantek ND, Hsu P, Meijer P, Smock KJ, Plumhoff EA, Refaai MA, Van Cott EM. Quality of Factor XI Activity Testing in North American Specialized Coagulation Laboratories. Int J Lab Hematol, 2015 May;37 Suppl 1:99-107.

5. Smock KJ, Ledford-Kraemer MR, Meijer P, Hsu P, Van Cott EM. Proficiency testing results for heparin-induced thrombocytopenia in North America. Semin Thromb Hemost. 2014 Mar;40(2):254-60.

6. Hsu P, Zantek ND, Meijer P, Hayward CP, Brody J, Zhang X, Smock KJ, Van Cott EM. Factor XIII Assays and Associated Problems for Laboratory Diagnosis of Deficiency: An Analysis of International Proficiency Testing Results. Semin Thromb Hemost. 2014 Mar;40(2):232-8.

7. Pruthi RK, Plumhoff EA, Nichols WL, Meijer P, Van Cott EM. Quality of Factor VIII Inhibitor Testing in North American Specialized Coagulation Laboratories. Am J Hematol in press (THSNA 2014 abstract/poster).

8. Black L, Selby R, Hoffman S, Chen D, Meijer P, Plumhoff EA, Van Cott EM. Anti-Xa assays for Unfractionated heparin (UFH) and Low molecular weight heparin (LMWH): Analysis of the Quality of Performance by North American laboratories. Am J Hematol in press (THSNA 2014 abstract/poster).

9. Chen D, Selby R, Meijer P, Plumhoff EA, Van Cott EM. Antithrombin Activity and Antigen Assays: An analysis of assay performance. Am J Hematol in press (THSNA 2014 abstract 173/poster).

10. Zantek ND, Hsu P, Meijer P, Plumhoff EA, Refaai MA, Smock KJ, Van Cott EM. Quality of Factor XI Activity Testing in North American Specialized Coagulation Laboratories. Am J Hematol in press (THSNA 2014 abstract/poster).

11. Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EM. Protein S: Quality of Testing in North American Specialized Coagulation Laboratories. Am J Hematol in press (THSNA 2014 abstract 112/poster).

12. Hsu P, Marlar RA, Zantek ND, Smock KJ, Plumhoff E, Meijer P, Van Cott EM. Activated Protein C Resistance Testing: Assessment of the Quality of Testing Performed by North American Specialized Coagulation

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Laboratories. Am J Hematol in press (THSNA 2014 abstract/poster). 13. Zantek ND, Hsu P, Refaai MA, Ledford-Kraemer M, Meijer P, Van Cott EM.

Factor VII assay performance: an analysis of the North American Specialized Coagulation Laboratory Association proficiency testing results. Int J Lab Hematol 2013; 35, 314–321.

14. Heikal NM, Smock KJ. Laboratory testing for platelet antibodies. Test of the Month. Am J Hematol 2013; Sep;88(9):818-21.

15. Hsu P, Zantek ND, Meijer P, Brody J, Zhang X, Smock KJ, Van Cott EM. Factor XIII Assays. A Problem for Laboratory Diagnosis? An Analysis of International Proficiency Testing Results. Abstract. International Journal of Laboratory Hematology 2013, in press.

16. Hayward CPM, Moffat KA. Laboratory testing for bleeding disorders: strategic uses of high and low-yield tests. Int J Lab Hematol. 2013 35, 322–333.

17. Hayward CPM. Improving blood disorder diagnosis: reflections on the challenges. Int J Lab Hematol in press 2013; pub Mar 11. DOI: 10.1111/ijlh.12074.

18. Yang D, Oberley M. Laboratory testing for cobalamin deficiency in megaloblastic anemia. Test of the Month. Am J Hematol 2013, in press.

19. Tcherniantchouk O, Laposata M, Marisa B. Marques MB. The isolated prolonged PTT. Test of the Month. Am J Hematol (Jan) 2013; 88:82–85.

20. Smock KJ, Ledford-Kraemer MR, Meijer P, Hsu P, Van Cott EM. Update on Proficiency Test Results for Heparin-Induced Thrombocytopenia: A Report from the North American Specialized Coagulation Laboratory Association (NASCOLA). Oral abstract, International Journal of Laboratory Hematology 2013.

21. Pruthi R. Inhibitor Testing. Oral presentation ISLH 2013. 22. Hayward CPM, Moffat KA, Plumhoff E, Timleck M, Hoffman S, Spitzer E,

Van Cott E, Meijer P. External Quality Assessment of Platelet Disorder Investigations: Results of International Surveys on Diagnostic Tests for Dense Granule Deficiency and Platelet Aggregometry Interpretation. Seminars in Thrombosis and Haemostasis 2012; Sep;38(6);622-631.

23. Kaatz A, Kouides PA, Garcia DA, Spyropolous AC, Crowther M, Douketis JD, Chan AKC, James A, Moll S, Ortel TL et al. Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. Am J Hematol 2012; May;87 Suppl 1:S108-12.

24. Hayward CPM, Moffat KA, Plumhoff E, Van Cott EM. Approaches to investigating common bleeding disorders: An evaluation of North American coagulation laboratory practices. Am J Hematol 2012; May;87 Suppl 1:S45-50.

25. Baron JM, Johnson SM, Ledford-Kraemer MR, Hayward CP, Meijer P, Van Cott EM. Protein C Assay Performance. An Analysis of North American Specialized Coagulation Laboratory Association Proficiency Testing Results. Am J Clin Pathol 2012; Jun;137(6):909-15.

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26. Zehnder J, Price E, Jin J. Controversies in heparin monitoring. Am J Hematol 2012; May;87 Suppl 1:S137-40.

27. Johnson NV, Khor B, Van Cott EM. Advances in laboratory testing for thrombophilia. Am J Hematol 2012; May;87 Suppl 1:S108-12.

28. Kim YA, Makar RS. Detection of fetomaternal hemorrhage. Am J Hematol 2012; Apr 87:417–423.

29. Gehrie E, Laposata M. Test of the Month: The chromogenic antifactor Xa assay. Am J Hematol 2012; Feb 87:194–196.

30. Arinsburg SA, Shaz BH, Westhoff C, Cushing MM. Determination of HPA Typing by Molecular Methods: Importance in Diagnosis and Early Treatment of NAIT. Am J Hematol 2012, May 87:525–528, 2012.

31. Zantek ND, Koepsell SA, Tharp DR, Cohn CS. The Direct Antiglobulin Test (DAT): A Critical Step in the Evaluation of Hemolysis. Am J Hematol 2012, July 87:707–709.

32. Moffat KA, Van Cott EM, Plumhoff E, Hayward CPM. Are Clinical Laboratories Following Published Guidelines for the Interpretation of Light Transmission Aggregometry? Results from a NASCOLA Patterns-of-Practice Survey. Abstract, Thrombosis and Hemostasis Summit of North America (THSNA), Chicago IL 2012.

33. Smock KJ, Ledford-Kraemer MR, Meijer P, Van Cott EM. Laboratory Testing for Heparin-Induced Thrombocytopenia: A Report from the North American Specialized Coagulation Laboratory Association (NASCOLA). Abstract, Thrombosis and Hemostasis Summit of North America (THSNA), Chicago IL 2012.

34. Zantek ND, Hsu P, Refaai MA, Ledford-Kraemer M, Meijer P, Van Cott EM. The North American Specialized Coagulation Laboratory Association Experience with Factor VII Proficiency Testing. Abstract, Thrombosis and Hemostasis Summit of North America (THSNA), Chicago IL 2012.

35. Pai M, Moffat KA, Plumhoff E, Hayward CP. Critical values in the coagulation laboratory: results of a survey of the North American Specialized Coagulation Laboratory Association. Am J Clin Pathol 2011; Dec 136(6):836-41.

36. Chandler W, Peerschke EIB, Castellone D, and Meijer P. von Willebrand Factor Assay Proficiency Testing, the North American Specialized Coagulation Laboratory Association Experience, Am J Clin Pathol 2011 Jun;135(6):862-899.

37. Smock KJ, Saunders PJ, Rodgers GM, Vandita Johari V. Laboratory Evaluation of Clopidogrel Responsiveness by Platelet Function and Genetic Methods. Am J Hematol 2011; Dec 86:1032-1034.

38. Marlar RA, Gausman JN. Protein S abnormalities: A diagnostic nightmare. Am J Hematol 2011; May;86(5):418-421.

39. Moffat K, Plumhoff E, Hoffman S, Van Cott E, Meijer P, Hayward C. International Proficiency Challenges for Platelet Light Transmittance Aggregation - Performance and Adherence to Published Guidelines in Diagnostic Laboratories, poster #811 ISLH May 2011.

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40. Baron J, Hayward C, Johnson S, Van Cott E. Protein C assays: an analysis of North American Specialized Coagulation Laboratory Association proficiency testing, poster #900 ISLH May 2011.

41. Hayward CM, Moffat KA, Raby A, Israels S, Plumhoff E, Flynn G, Zehnder JL. Development of North American Consensus for Medical Laboratories That Perform and Interpret Platelet Function Testing Using Light Transmission Aggregometry. Am J Clin Pathol 2010; 134:955-963.

42. Khor B, Van Cott EM. Laboratory tests for antithrombin deficiency. Am J Hematol 2010 (Dec);85(12):947-50.

43. Dembitzer FR, Ledford Kraemer MR, Meijer P, Peerschke EIB. Lupus anticoagulant testing: performance and practices by North American clinical laboratories. Am J Clin Pathol 2010 (Nov); 134: 764-773.

44. Otis SA, Zehnder JL. Heparin-induced thrombocytopenia: Current status and diagnostic challenges. Am J Hematol, 2010 (Sep); 85(9): 700-706.

45. Ledford-Kraemer MR. Analysis of von Willebrand Factor (VWF) Structure by Multimer Analysis. Am J Hematol, 2010 (July); 85(5): 510-514.

46. Smock KJ, Rodgers GM. Laboratory evaluation of aspirin responsiveness. Am J Hematol 2010; May;85(5):358-60.

47. Khor B, Van Cott EM. Laboratory tests for protein C deficiency. Am J Hematol 2010; Jun;85(6):440-2.

48. Moffat KA, Plumhoff E, Israels S, Timleck M, Spitzer E, Reyes E, Hoffman S, Meijer P, Hayward CPM. A review of experiences with external quality assessment challenges for several platelet function disorder assays offered by the North American Specialized Coagulation Laboratory Association. Poster for 2010 HTRS/NASCOLA Scientific Symposium, Chicago IL, April 15 – 17, 2010.

49. Castellone D, Van Cott EM. Laboratory monitoring of new anticoagulants. Am J Hematol 2010 Mar;85(3):185-187.

50. Van Cott EM. All that glitters is gold? Am J Hematol. 2010 Apr;85(4):223-224.

51. Smock KJ, Rodgers GM. Laboratory identification of lupus anticoagulants. Am J Hematol 2009 Jul;84(7):440-442.

52. Nichols WL, Rick ME, Ortel TL, Montgomery RR, Sadler JE, Yawn BP, James AH, Hultin MB, Manco-Johnson MJ, Weinstein M. Clinical and laboratory diagnosis of von Willebrand disease: a synopsis of the 2008 NHLBI/NIH guidelines. Am J Hematol. 2009 Jun;84(6):366-370.

53. Peerschke EI, Castellone DD, Ledford-Kraemer M, Van Cott EM, Meijer P. Laboratory assessment of factor VIII inhibitor titer: the North American Specialized Coagulation Laboratory Association experience. Am J Clin Pathol. 2009 Apr;131(4):552-558.

54. Hayward CPM, Moffat KA, Spitzer E, Timleck M, Plumhoff E, Israels SJ, White J. Results of an external proficiency testing exercise on platelet dense granule deficiency testing by whole mount electron microscopy. Am J Clin Pathol. 2009 May;131(5):671-675.

55. Moffat KA, Ledford-Kraemer MR, Plumhoff EA, McKay H, Nichols WL,

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Meijer P, Hayward CPM. Are laboratories following published recommendations for lupus anticoagulant testing? An international evaluation of practices. Thromb Haemost. 2009 Jan;101(1):178-184.

56. Cattaneo M, Hayward CPM, Moffat KA, Pugliano MT, Liu Y, Michelson AD. Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH. J Thromb Haemost 2009;7:1029.

57. Pai M, Moffat KA, Plumhoff EA, Adcock DM, Zehnder JL, Hayward CPM. Critical values in the coagulation laboratory: Results of a survey of the North American Specialized Coagulation Laboratory Association. 51st ASH Annual Meeting and Exposition, December 5 – 8, 2009. Blood 2009; 114(22); Abst # 1415.

58. Moffat KA, Plumhoff E, Reyes E, Hoffman S, Israels S, Meijer P, Hayward CPM. The interpretation of light transmittance platelet aggregation is inconsistent – Results from an international challenge. XXIInd Congress of the International Society on Thrombosis and Haemostasis. Boston, USA, July 11-16, 2009. Oral Communication. Journal of Thrombosis and Haemostasis 2009; 7(Suppl 2) [on CD-ROM]: Abst OC-MO-134.

59. Verhovsek M, Moffat KA, Hayward CP. Laboratory testing for fibrinogen abnormalities. Am J Hematol. 2008 Dec;83(12):928-931.

60. Abstracts: 2nd Mayo/NASCOLA Coagulation Testing Quality Conference. Am J Hematol 2008(Dec);83(12):941-948.

61. Price EA, Hayward CP, Moffat KA, Moore JC, Warkentin TE, Zehnder JL. Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: a survey of North American specialized coagulation laboratories. Thromb Haemost. 2007 Dec;98(6):1357-1361.

62. Olson JD, Preston FE, Nichols WL. External Quality Assurance in Thrombosis and Hemostasis: An International Perspective. Semin Thromb Hemost 2007;33:220–225.

63. Van Cott EM, Ledford-Kraemer M, Meijer P, Nichols WL, Johnson SM, Peerschke EIB. Protein S: An Analysis of the North American Specialized Coagulation. Laboratory Association Proficiency Testing. Am J Clin Pathol 2005; 123: 778-785.

64. Moffat KA, Ledford-Kraemer MR, Nichols WL, Hayward CP. Variability in clinical laboratory practice in testing for disorders of platelet function: results of two surveys of the North American Specialized Coagulation Laboratory Association. Thromb Haemost. 2005 Mar;93(3):549-553.