APAC CRO Market A deep dive into the trends transforming ... · A deep dive into the trends transforming APAC CRO industry P86A-52 June 2015. P86A-52 2 Table of Contents ... • Competitive

APAC CRO MarketA deep dive into the trends transforming APAC CRO

industry

P86A-52 June 2015

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Table of Contents

Section Slide Numbers

Executive Summary 10

• Key Findings 11

• Total CRO Market Size – By Stages of Clinical Development 16

• Market Size Estimation Methodology 17

• Scope and Segmentation 18

• Key Questions This Study Will Answer 19

• Total CRO Market Engineering Measurements 20

• CEO’s Perspective 21

• Key Companies to Watch 22

• 3 Big Predictions 24

Market Overview 26

• R&D Spending – Pharmaceutical Drug Development 27

• Market Perspective 28

• R&D Market Landscape 29

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Table of Contents


• CRO Product Development & Commercialization 30

• Total CRO Market Segmentation – By Stages of Clinical Development 31

• Total CRO Market Segmentation – By Therapeutic Services 32

• Key Market Trends 33

• eClinical solutions – An Overview 34

• eClinical solutions – Applications & Technologies 35

• Rise of Virtual Business Models 36

Competitive Playbook 37

• New Market Opportunities 38

• Merger, Acquisition, and Partnership Assessment 42

• Competitive Matrix 44

Drivers, Restraints, and Trends 45

• Market Drivers 46

• Market Restraints 47

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Table of Contents


Forecasts and Trends – Total Market 48

• Forecast Assumptions 49

• Total CRO Market Engineering Measurements 50

• Total CRO Market – Revenue Forecast 52

• Total CRO Market – Revenue Forecast Discussion 53

• Key Market Trends 54

• Key Market Trends Explained 55

Competitive Environment 58

• Competitive Analysis – Market Share 59

• Market Share Analysis 60

• Competitive Environment 61

• Competitive Analysis – Selected Key Market Participants 62

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CRO Segment Analysis 70

• Pre-clinical Trials Segment 71

• Segment Overview 72

• Market Engineering Measurements 73

• Revenue Forecast 74

• Key Trends 76

• Phase I Trials Segment 77




• Key Trends 82

• Phase II Trials Segment 83


Table of Contents (continued)

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• Key Trends 88

• Phase III Trials Segment 89




• Key Trends 94

• Phase IV Trials Segment 95




• Key Trends 100


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• Data Management Segment 101




• Key Trends 106

• Biostatistics Segment 107




• Key Trends 112

• Pharmacovigilance Segment 113




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• Key Trends 118

• Health Economics & Outcomes Research (HEOR) Segment 119




• Key Trends 124

• Bioanalytics Segment 125




• Key Trends 130

• Central Laboratory Services Segment 131


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• Key Trends 136

The Last Word 137

Legal Disclaimer 140

Appendix 141


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Market Size Estimation Methodology

Frost & Sullivan followed a three-step methodology to develop the analysis:

The information above was analysed and aggregated to produce this research service.

Frost & Sullivan uses the expertise of the global research staff

supported by the internal databases to develop insights into the

contract research market.

Secondary research is utilised to develop a baseline understanding of

the contract research industries as well as to identify key stakeholders

for the primary research phase.

Approximately 80 percent to 90 percent of the data provided in the

primary research is focused on obtaining targeted information from key

market participants by means of telephone and face to face interviews.

2. Secondary Research

3. Primary Research

1. Internal Expertise

Source: Frost & Sullivan

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Scope and Segmentation

Scope

Geographic coverage Asia Pacific

Study period 2014–2019

Base year 2014

Forecast period 2015–2019

Monetary unit US Dollars

This research service analyses the APAC clinical trials and research outsourcing (CRO) market.

It provides revenue forecasts for CROs in Asia Pacific by phase, therapeutic type and country.

The research study addresses the major issues and challenges, unmet needs and emerging trends in the market. Also, outlines market drivers and restraints and R&D trends.


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Key Questions This Study Will Answer

How will contract research outsourcing help in drug development by saving time and cost for manufacturers?

What is the impact of the market growth in different regions?

Who are the predominant market participants in the CRO market and their market share contribution?

What are the key market trends observed towards expansion of contract research organizations in drug development across key therapeutic areas?

Are the products/services offered today meeting customer needs or is additional development needed?

What are the key market segments to look out for and what are the key trends followed in the market?


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CRO Product Development & Commercialization


Pre-clinical

Product Development Approval

Health Economic and outcome research (HEOR)

Phase I Phase II Phase III Phase IV

Central Laboratory Services

Biostatistics

Data Management

Late PhaseInterventional

Late PhaseObservational

Late Phase Pharmacovigilance

Other HealthcareSolutions

Commercialization

Bio-analyticsBio-analytics

Total CRO Market: Stages of Clinical Development, APAC, 2014

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Demand for new and effective

medication

Growing IT-enabled offerings

Data analytics to

witness radical growth

Evolving regulations

Quick time to market

model

Increase in laboratory

testing outsourcing

Demand for late-stage

development services

Central hub for novel

drug delivery

For detailed version, click here.

Key Market Trends

Rapid Consolidation

through strategic

M&As


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CEO’s Perspective

2

Originator companies to conduct more local

studies in order to generate pharmaco-

economic data to support the listing of

medical impairments (blue book listing).

3eClinical technologies will completely

transform the way data management is being

carried out today.

4Regulatory co-operation in the Asia region

will offers the prospect of greater

harmonisation on clinical trial requirements.

1Global CROs will continue to merge or

acquire local CROs as a strategic means to

establish their presence in Asia Pacific


5Co-drug development model will be the future

of drug development industry

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Sample of Key Highlights

• The Asia Pacific CRO market was $XXX billion in 2014 and is expected to reach $XXX billion in

2019, growing at a robust CAGR of XXX% from 2014 to 2019.

• APAC holds the third largest share of the CRO market and held XXX per cent share of the total

global CRO market in 2014.

• The share of services, such as Data management, Biostatistics, Health Economics and Outcomes

Research and Central Laboratory Services, is expected to grow at a double digit rate in next 5-6

years.

• Geographic outsourcing to low-cost locations is likely to result in lesser margins in the short term,

but higher volume share. However, with increased capacity and scale, companies are expected to

improve their margins during rest of the forecast period.

• Specialized services such as eClinical trial solutions, adaptive trial designs and outcomes research

are expected to transform the way clinical trials are performed today.

• Asia Pacific is experiencing tremendous growth in R&D spending, driven by increased globalization

of the pharmaceutical and biotechnology markets and low-cost advantage, which supports volume

growth.

Source: Frost & Sullivan analysis.

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Partial List of Companies Interviewed

• CMIC Co. Ltd

• Covance, Inc.

• CliniTech

• InVentiv health

• INC Research

• LSK Global Pharma Service

• Novotech (Australia) Pty Ltd

• PAREXEL International

• Pharmaceutical Product Development

(PPD)

• PhaseON Clinical Research Pvt. Ltd

• PRA International

Source: Frost & Sullivan research.

• QUANTICATE LTD

• Quintiles

• SGS Life Sciences

• Tigermed Consulting Ltd.

• WuXi PharmaTech

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APAC CRO Market A deep dive into the trends transforming ... · A deep dive into the trends transforming APAC CRO industry P86A-52 June 2015. P86A-52 2 Table of Contents ... • Competitive