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Anti-obesity effects of gut microbiota are associated with lactic acidbacteria

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Abstract

The prevalence of obesity is rapidly becoming endemic in industrialized countries and continues to increase in developing

countries worldwide. Obesity predisposes people to an increased risk of developing metabolic syndrome. Recent studies

have described an association between obesity and certain gut microbiota, suggesting that gut microbiota might play a critical

role in the development of obesity. Although probiotics have many beneficial health effects in humans and animals, attention

has only recently been drawn to manipulating the gut microbiota, such as lactic acid bacteria (LAB), to influence the

development of obesity. In this review, we first describe the causes of obesity, including the genetic and environmental

factors. We then describe the relationship between the gut microbiota and obesity, and the mechanisms by which the gut

microbiota influence energy metabolism and inflammation in obesity. Lastly, we focus on the potential role of LAB in

mediating the effects of the gut microbiota in the development of obesity.

Yueh-Ting Tsai and Po-Ching Cheng contributed equally to this work.Page %P

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Within this Article

1. Introduction

2. Causes of obesity

3. Obesity and gut microbiota

4. Obesity and lactic acid bacteria

5. Conclusion

6. References

7. References

Related Content

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About this Article

TitleAnti-obesity effects of gut microbiota are associated with lactic acid bacteria

JournalApplied Microbiology and Biotechnology Volume 98, Issue 1 , pp 1-10

Cover Date2014-01-01

DOI10.1007/s00253-013-5346-3

Print ISSN0175-7598

Online ISSN1432-0614

PublisherSpringer Berlin Heidelberg

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Topics

Microbiology

Microbial Genetics and Genomics

Biotechnology

Keywords

Lactic acid bacteria

Anti-obesity effects

Gut microbiota

Probiotics

Lipid metabolism

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Authors

Yueh-Ting Tsai (1)

Po-Ching Cheng (2) (3)

Tzu-Ming Pan (1)

Author Affiliations

1. Department of Biochemical Science and Technology, College of Life Science, National Taiwan

University, No. 1, Sec. 4, Roosevelt Road, Taipei, 10617, Taiwan

2. Department of Parasitology, School of Medicine, College of Medicine, Taipei Medical University,

Taipei, Taiwan

3. Center for International Tropical Medicine, School of Medicine, College of Medicine, Taipei

Medical University, Taipei, Taiwan

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