Annual NATA Symposium on Patient Blood … Promt5 Dear Colleague, On behalf of the NATA board of directors, it is my pleasure to welcome you to the 16th NATA Symposium on Patient Blood

Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis

I Blood Procurement and Transfusion RisksI Optimising the Practice of TransfusionI Management of the Bleeding PatientI Treatment of Anaemia and Iron Deficiency in

Patient Blood ManagementI Burning Questions on Haemostasis

and ThrombosisI Pro/Con Debate:

Using a Fixed RBC:FFP:PLT Ratio in Massively Bleeding Patients

I Best PostersI Breaking NewsI Workshops

www.nataonline.com

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Final Programme

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General InformationWelcome Message 5

About NATA 6

Organising Committee 8

Scientific Committee 8

Faculty 8

CME Accreditation 8

Congress Information 9

Information for Speakers 9

Information for Poster Presenters 9

Scientific ProgrammeThursday, April 16 10

Friday, April 17 11

Poster Visit Schedule 12

Posters 13

Industry Programme and ExhibitionNATA Partners 22

Industry-Sponsored Symposia and Lectures 22

Sponsors and Exhibitors 24

Exhibition Floor Plan 26

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16th Annual NATA Symposium

You are Cordially Invited to Our Scientific Symposium at NATA 2015 in Prague

Latest Strategies in Patient BloodManagement: New Monitoring TrendsLocation: Main AuditoriumChairperson: Kai ZacharowskiDate & Time: Thursday, April 16th · 12:45 – 14:15 Lunch will be provided

Surgical Patients & Anemia: Patient Blood Management

Univ.-Prof. Dr. Kai Zacharowski, FRCA

Direktor Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie,Universitätsklinikum Frankfurt, Germany

Presenters

The Cambridge Experience: Optimizing TransfusionDecisions and Post-op Internal Bleeding Detection

Vishal Patil, MD

Consultant Anaesthetist, Quality and Safety Lead for Adult Intensive Careand Perioperative Services.Cambridge University Hospitals NHS Foundation TrustCambridge, UK

Patient Blood Management and Transfusion Optimization

Juan V. Llau, MD, PhD

Servicio de Anestesiología-Reanimación. Hospital Clínic Universitari de ValenciaProfesor Asociado de Fisiología. Universidad de Valencia.Department of Anesthesiology and Critical Care. Hospital Clínic Universitari - ValenciaAssociated Professor of Physiology. University of Valencia, Spain

For more information, please stop by Stand 8.

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MAS_NATA_2015_Satellite_Programm_V8.pdf 1 31.03.2015 12:27:13

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Dear Colleague,

On behalf of the NATA board of directors, it is my pleasure to welcome you to the 16th NATA Symposium on Patient Blood Management, Haemostasis and Thrombosis that is taking place in Prague, Czech Republic. Whether you participated or not in the first NATA symposium in Prague – 10 years ago, already! – no doubt we will all enjoy (re)discovering this historical and architectural jewel of Central Europe.

Every year NATA attracts a wide international and multidisciplinary audience, allowing delegates to share their experiences and network with a variety of specialists in their respective fields of interest.

In line with our new mission statement – Promoting optimal patient blood management, haemostasis and thrombosis in everyday clinical practice through a multidisciplinary approach – the scientific programme covers a wide range of topics that is sure to interest anaesthesiologists, intensivists, surgeons, haematologists and transfusion medicine specialists.

This year, notwithstanding our well-established areas of interest, special emphasis will be placed on evidence-based transfusion practice, optimal management of bleeding, and the role of iron therapy in patient blood management.

The scientific programme includes four practical workshops where a limited number of participants will be offered an excellent opportunity for clinical discussions and exchange of experience. The topics, carefully selected by the scientific committee for these interactive workshops, are: available technologies for cell salvage, management of massive bleeding, perioperative and emergency management of oral anticoagulants, and design and conduct of clinical trials in transfusion medicine.

Finally, don’t miss out on our special, annual features: the best posters’ presentations and the late-breaking news session present upcoming and recently completed research. No doubt they will stir up a lot of discussion!

More than ever, the annual NATA symposium will provide a unique opportunity for stimulating and constructive exchanges across different specialities involved in patient blood management.

Yours sincerely,

Jean-François HardyNATA Chair

Welcome to the 16th Annual NATA Symposium

TRANSFUSION MEDICINE Becomes NATA’s Official Journal!

TO ACCESS:

Log-in at www.nataonline.com Go to “Members Area”

Open “Access to Transfusion Medicine Journal”

Click on “Wiley Online Library - Transfusion Medicine”.

1

2

3

4

NATA members have FREE ACCESS to Transfusion Medicine

Why read or submit to Transfusion Medicine? • Accepts articles on transfusion medicine in its widest context, including blood

transfusion practice, immunohaematology, immunogenetics, histocompatibility, medico-legal applications, and related molecular biology and biotechnology.

• Of relevance to practising clinicians who want practical answers

• Online Submission

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NATA’s Educational Activities

Annual Symposium, Regional Symposia and Expert Meetings

NATA has organised 15 annual symposia in Europe since 2000, with an average attendance ranging between 500 and 600 delegates from around 40 countries. It has also organised several regional symposia (1 in North America and 4 in Asia-Pacific) and a number of sessions or partic-ipations at other societies’ international and local congresses. NATA has also organised expert meetings that have led to the publication of a Seminars in Hematology supplement on the role of intravenous iron in anaemia management, a consensus statement on the role of intravenous iron in perioperative anaemia management (Beris P et al. Br J Anaesth 2008;100:599-604), and guidelines for the detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient (Goodnough LT et al. Br J Anaesth 2011;106:13-22). A

series of expert meetings on patient blood management in obstetrics, organised in collaboration with other medical associations, is underway.

NATA has also endorsed the recently updated European guideline for the management of bleeding and coagulopathy following major trauma (Spahn DR et al. Crit Care 2013;17:R76) and has been invited to nominate representatives into European Society of Anaesthesiology task forces perioperative venous thrombosis and perioperative bleeding.

Publishing

Between 1999 and 2012 NATA published the journal Transfu-sion Alternatives in Transfusion Medicine (TATM), with Wiley as publisher from 2006 to 2012.

In January 2014 the journal of the British Society of Blood Transfusion, Transfusion Medicine, also published by Wiley, has become NATA’s official journal. Online subscription to the jour-nal is included in NATA’s membership benefits.

Web and Multimedia

The Nataonline website (www.nataonline.com) was re-launched in 2011 with a new graphic design. A new educational content is being developed, including focused updates, news as well as a dedicated area for NATA members. A weekly review of the literature is performed and selected articles are graded and summarised by scientific committee members. Since 2014 literature updates are also posted on twitter and on NATA’s LinkedIn group.

E-learning is emerging as an attractive tool for continuing medical education (CME). The board of directors has therefore decided to launch an e-learning programme to be hosted on a platform connected to Nataonline. The plan is to develop a series of CME-accredited e-learning modules covering NATA’s main topics of interest.

About NATA

What Is NATA?NATA, the Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis, is unique in that it provides a multidisciplinary forum for dialogue between haematologists, blood bankers, anaesthesiologists, surgeons and other healthcare pro-fessionals interested in promoting best clinical practice in the fields of patient blood management, haemostasis and thrombosis.

Recently NATA’s mission statement – Promoting optimal patient blood management, haemostasis and thrombosis in everyday clinical practice through a multidisciplinary approach – was modified in order to better reflect the various clinical issues encountered in the management of anaemia, bleeding and thrombosis.

www.KRSTA.org

OCT. 3-4, 2013 SEOUL, KOREAPERIOPERATIVE ANEMIA

BLOOD MANAGEMENT AND SURGERYBLOOD CONSERVATION STRATEGIES

FLUID THERAPYPERIOPERATIVE HEMOSTASIS & THROMBOSIS

MANAGEMENT OF CRITICAL BLEEDINGMANAGEMENT OF CRITICAL BLEEDING

2013

KRSTA–NATAJOINT SYMPOSIUM

July 28-29, 2007

Congress venue:Hotel Bumi KarsaBidakara Complex

Pekin

Jointly organized by NATA and the Chinese Society of Anesthesiology

BEIJ

ING

Transfusion Medicine and Alternatives

ASIAN NATA

S Y M P O S I U M4TH

[ EFFICACY OF TRANSFUSION [ COMPLICATIONS OF TRANSFUSION

[ PERIOPERATIVE VOLUME REPLACEMENT [ THROMBOSIS AND HEMOSTASIS

[ TRANSFUSION STRATEGIES IN TRAUMA

[ TRANSFUSION ALTERNATIVES IN CARDIOTHORACIC SURGERY

[ PRO AND CON DISCUSSION: PERIOPERATIVE FLUID MANAGEMENT

[ REDUCING ALLOGENEIC TRANSFUSION NEEDS

Alternatives to Blood Transfusion in Transfusion Medicine

Edited byAlice Maniatis, Philippe Van der Linden and Jean-François Hardy

SECOND EDITION

Volume 24 Supplement 1 April 2014www.transfusionmedjournal.com

Offi cial Journal of the British Blood Transfusion Society and the Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis

TRANSFUSIONMEDICINE

Abstracts of the 15th Annual NATA SymposiumApril 10–11, 2014Porto, Portugal

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nata14th Annual Symposium

Blood Transfusion Services/ Risk of Transfusion

Transfusion Practice

Blood Conservation Strategies/ Autologous Transfusion

Anemia Effects and Management

Fluid Therapy/Oxygen Carriers

Hemostasis & Thrombosis

2013, April 12-13 VIENNA Austria

Dead l i ne fo r abs t rac t submiss i on : December 1 , 2012


In 2000 NATA published a textbook entitled Transfusion Medi-cine and Alternatives to Blood Transfusion. The full text of this edition is available free of charge on the Nataonline website. The second edition of the NATA textbook, entitled Alternatives to Blood Transfusion in Transfusion Medicine, was published in 2010 in collaboration with Wiley. The book includes 47 chapters contributed by recognised experts from various specialities.


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Congress Informatio n

CME AccreditationThe 16th Annual Symposium on Patient Blood Management, Haemostasis and Thrombosis is accredited by the European Accreditation Council for Continuing

Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net.The 16th Annual NATA Symposium is designated for a maximum of 11 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme.Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada.

EACCME creditsEach medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The EACCME credit system is based on 1 ECMEC per hour with a maximum of 3 ECMECs for half a day and 6 ECMECs for a full-day event.

The 16th Annual Symposium on Patient Blood Management, Haemostasis and Thrombosis is compliant with the Eucomed Code of Ethical Business Practice.

Congress VenueThe 16th Annual NATA Symposium is taking place at the Prague Congress Centre 5. kvetna 65 140 21 Prague 4Czech Republic

Registration DesksRegistrations desks are located on Level 1of the Prague Congress Centre.

Attendees Deskis opened at the following times: Thursday, April 16: 8:00–18:30Friday, April 17: 8:00–18:00

Exhibitors DeskExhibitors should collect their exhibitor badges from this desk. Exhibitors desk is opened at the following times: Wednesday, April 15: 8:00–18:00Thursday, April 16: 8:00–18:30Friday, April 17: 8:00–18:30

Coffee BreaksCoffee breaks are scheduled as follows: 10:30–11:00 on Thursday and Friday 16:00–16:30 on Thursday and Friday

Exhibition Area Opening HoursThursday, April 16: 8:45–17:30Friday, April 17: 9:00–16:45

BadgesFor security purposes, delegates, accompanying persons and exhibitors must wear their name badges.

Certificates of AttendanceDelegates will receive a certificate of attendance when handing in their completed evaluation form at the registration desk.

Congress BagsCongress bags are given to all delegates when they register.

NATA General AssemblyNATA members are invited to participate in the NATA General Assembly, which will take place on April 16 from 17:45 to 18:30 at the NATA Office (room 2.2) on Level 2 of the Congress Centre.

NATA Scientific Committee MeetingNATA Scientific Committee members are invited to participate in a breakfast meeting on April 17 from 7:30 to 8:30 at the NATA Office (room 2.2) on Level 2 of the Congress Centre.

Information for SpeakersSpeakers’ Room: room 2.3 on Level 2 of the Congress Centre.

Opening Hours: Thursday, April 16: 8:00–18:00Friday, April 17: 8:15–16:00

Please bring your slide presentation to the Speakers’ Room at least 1 hour before you are scheduled to present. Computers will be available in the room and technical assistance will be provided should you need help with your presentation.

Information for Poster PresentersPosters will be displayed during the two symposium days in the exhibition area on Level 2 of the Congress Centre. The schedule of poster visits can be found on page 12.

OrganisingCommitteeChairsJ.-F. Hardy, Montreal, QC, Canada

MembersE. Bisbe, Barcelona, SpainH. Gombotz, Linz, AustriaP. I. Johansson, Copenhagen, DenmarkJ. Meier, Linz, AustriaR. Moog, Cottbus, GermanyM. Muñoz, Málaga, SpainC.-M. Samama, Paris, FranceD. Thomas, Swansea, Wales, UK

ScientificCommitteeChairC.-M. Samama, Paris, France

MembersM. Auerbach, Baltimore, MD, USAE. Bisbe, Barcelona, SpainF. Bonhomme, Geneva, SwitzerlandM.-P. Bonnet, Paris, FranceC. Breymann, Zurich, SwitzerlandK. Brohi, London, UKJ. L. Carson, New Brunswick, NJ, USAD. Faraoni, Boston, MA, USAT. Frietsch, Marburg, GermanyJ. A. García-Erce, Huesca, SpainA. Godier, Paris, FranceH. Gombotz, Linz, AustriaL. T. Goodnough, Stanford, CA, USAJ.-F. Hardy, Montreal, QC, Canada

O. Habler, Frankfurt, GermanyE. Hansen, Regensburg, GermanyB. J. Hunt, London, UKG. Inghilleri, Milan, ItalyM. Intaglietta, La Jolla, CA, USAP. I. Johansson, Copenhagen, DenmarkC. G. Koch, Baltimore, MD, USAS. A. Kozek-Langenecker, Vienna, AustriaJ. Lacroix, Montreal, QC, CanadaS. Lasocki, Angers, FranceS. R. Leal-Noval, Seville, SpainM. Levi, Amsterdam, The NetherlandsJ. V. Llau, Valencia, SpainJ. Meier, Linz, AustriaR. Moog, Cottbus, GermanyH. Morimatsu, Okayama, JapanM. Muñoz, Málaga, SpainH. V. New, London, UKS. Ostrowski, Copenhagen, DenmarkY. Ozier, Brest, FranceM. Pavesi, Milan, ItalyM. Piagnerelli, Charleroi, BelgiumT. Richards, London, UKR. Rossaint, Aachen, GermanyC. So-Osman, Leiden, The NetherlandsJ. Stensballe, Copenhagen, DenmarkD. Thomas, Swansea, Wales, UKA. G. Tsai, La Jolla, CA, USAC. E. Vagianos, Piraeus, GreeceP. Van der Linden, Brussels, BelgiumC. von Heymann, Berlin, Germany

FacultyE. Bisbe, Barcelona, SpainC. A. Branch, Bronx, NY, USAC. Breymann, Zurich, Switzerland

J. L. Carson, New Brunswick, NJ, USAJ. Cermak, Prague, Czech RepublicV. Černý, Ústí nad Labem, Czech RepublicI. Čundrle, Brno, Czech RepublicK. Cvachovec, Prague, Czech RepublicL. Douay, Paris, FranceD. Faraoni, Boston, MA, USAZ. Gašová, Prague, Czech RepublicH. Gombotz, Linz, AustriaL. T. Goodnough, Stanford, CA, USAJ.-F. Hardy, Montreal, QC, CanadaL. B. Holst, Copenhagen, DenmarkB. J. Hunt, London, UKP. I. Johansson, Copenhagen, DenmarkS. A. Kozek-Langenecker, Vienna, AustriaJ. Lacroix, Montreal, QC, CanadaM. Levi, Amsterdam, The NetherlandsJ. V. Llau, Valencia, SpainJ. Meier, Linz, AustriaR. Moog, Cottbus, GermanyM. Muñoz, Málaga, SpainG. Murphy, Leicester, UKY. Ozier, Brest, FranceS.-R. Pasricha, Oxford, UKV. Patil, Cambridge, UKR. Pinciroli, Boston, MA, USAK. E. Puca, Milwaukee, WI, USAP. Salaj, Prague, Czech RepublicC.-M. Samama, Paris, FranceJ. Stensballe, Copenhagen, DenmarkD. Thomas, Swansea, Wales, UKP. Van der Linden, Brussels, BelgiumJ. van der Linden, Stockholm, SwedenC. von Heymann, Berlin, GermanyA. Wikkelsø, Copenhagen, DenmarkK. Zacharowski, Frankfurt, Germany


nata 2015 10 nata 2015 11

8:45-9:00 Welcome Address Jean-François Hardy, Montreal, QC, Canada

(No parallel session)

BLOOD PROCUREMENT AND TRANSFUSION RISKS Rainer Moog, Cottbus, Germany • Zdenka Gašová, Prague, Czech Republic

9:00-9:20 Donor Iron Deficiency – An Emerging Donation Safety ConcernSant-Rayn Pasricha, Oxford, UK

9:20-9:40 Stem-Cell-Derived Blood Products: Present and FutureLuc Douay, Paris, France

9:40-10:00Transfusion-Related Immunomodulation: Yes, but What Does It Do to Our Patients?Jeffrey L. Carson, New Brunswick, NJ, USA

10:00-10:30 Questions and Answers

10:30-11:00 Break

OPTIMISING THE PRACTICE OF TRANSFUSION Hans Gombotz, Linz, Austria • Karel Cvachovec, Prague, Czech Republic > W O R K S H O P

MANAGEMENT OF MASSIVE BLEEDING

Sibylle A. Kozek-Langenecker, Vienna, Austria

Pär I. Johansson, Copenhagen, Denmark

> W O R K S H O P

MANAGEMENT OF PATIENTS ON ORAL ANTICOAGULANTS

Charles-Marc Samama, Paris, France

Marcel Levi, Amsterdam, The Netherlands

11:00-11:20 Red Blood Cell Transfusion in Cardiac SurgeryGavin Murphy, Leicester, UK

11:20-11:40Real-Time Clinical Decision Support to Improve Blood UtilizationLawrence Tim Goodnough, Stanford, CA, USA

11:40-12:00 Methods to Implement Patient Blood ManagementKai Zacharowski, Frankfurt, Germany


12:30-14:30 Lunch Break • Industry-Sponsored Satellite Symposia and Workshops

MANAGEMENT OF THE BLEEDING PATIENT Pär I. Johansson, Copenhagen, Denmark • Vladimir Černý, Ústí nad Labem, Czech Republic

> W O R K S H O P

HOW TO SET UP A CLINICAL TRIAL

Beverley J. Hunt, London, UK

Jeffrey L. Carson, New Brunswick, NJ, USA

> W O R K S H O P

CELL SALVAGE FOR THE INEXPERIENCED—AN OVERVIEW OF THE AVAILABLE TECHNOLOGIES

Dafydd Thomas, Swansea, Wales, UK

Jens Meier, Linz, Austria

14:30-14:50Crystalloids vs. Starches vs. Albumin: the Never-Ending QuestionPhilippe Van der Linden, Brussels, Belgium

14:50-15:10 Should We Be Using Fibrinogen Concentrate or Cryoprecipitate?Jakob Stensballe, Copenhagen, Denmark

15:10-15:30 Antifibrinolytics to Reduce or Prevent BleedingYves Ozier, Brest, France


16:00-16:30 Break

BEST POSTERS’ PRESENTATION Charles-Marc Samama, Paris, France • Karel Cvachovec, Prague, Czech Republic


16:30-16:45Autologous Transfusion of Stored Red Blood Cells Increases Pulmonary Artery PressureRiccardo Pinciroli, Boston, MA, USA

16:45-17:00Impact of Individual Physician Blood Reports and “1 vs. 2 Unit” Metric to Lower Red Blood Cell TransfusionsKathleen E. Puca, Milwaukee, WI, USA

17:00-17:15Cerebrovascular Response to Infusion of EAF P5K6-Alb, NO Producing, Colloidal Plasma Volume Expander, Is Muted in Transgenic Mouse Models of Sickle Cell DiseaseCraig A. Branch, Bronx, NY, USA

17:15-17:30Tranexamic Acid Reduces Transfusion Requirements in Adult Major Spine SurgeryJean-François Hardy, Montreal, QC, Canada

17:45-18:30 NATA General Assembly

THURSDAY, April 16, 2015 FRIDAY, April 17, 2015

BREAKING NEWSJean-François Hardy, Montreal, QC, Canada • Dafydd Thomas, Swansea, Wales, UK


8:40-9:00Length of Red Blood Cell Storage and Clinical Outcomes in Transfused Critical Ill Adults—The Age of Blood Evaluation (ABLE) Randomised Controlled TrialJacques Lacroix, Montreal, QC, Canada

9:00-9:20Liberal Versus Restrictive Red Blood Cell Transfusion in ICU Patients with Septic Shock—The Transfusion Requirements in Septic Shock (TRISS) TrialLars B. Holst, Copenhagen, Denmark

9:20-9:40Long-Term Mortality in the Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS)Jeffrey L. Carson, New Brunswick, NJ, USA

9:40-10:00Fibrinogen Concentrate as Initial Treatment for Postpartum Haemorrhage: FIB-PPH StudyAnne Wikkelsø, Copenhagen, Denmark


10:30-11:00 Break

TREATMENT OF ANAEMIA AND IRON DEFICIENCY IN PATIENT BLOOD MANAGEMENTManuel Muñoz, Málaga, Spain • Jaroslav Cermak, Prague, Czech Republic

> W O R K S H O P

HOW TO SET UP A CLINICAL TRIAL

Beverley J. Hunt, London, UK

Jeffrey L. Carson, New Brunswick, NJ, USA

> W O R K S H O P

MANAGEMENT OF PATIENTS ON ORAL ANTICOAGULANTS

Charles-Marc Samama, Paris, France

David Faraoni, Brussels, Belgium

11:00-11:20 Anaemia Does Not Fatigue You; Functional Iron Deficiency DoesLawrence Tim Goodnough, Stanford, CA, USA

11:20-11:40Management of Anaemia and Iron Deficiency in Pregnancy and in the Postpartum Period Christian Breymann, Zurich, Switzerland

11:40-12:00 Management of Anaemia and Iron Deficiency in Elective Surgical PatientsElvira Bisbe, Barcelona, Spain


12:30-14:30 Lunch Break • Industry-Sponsored Satellite Symposia and Workshops

BURNING QUESTIONS ON HAEMOSTASIS AND THROMBOSISCharles-Marc Samama, Paris, France • Peter Salaj, Prague, Czech Republic

> W O R K S H O P

MANAGEMENT OF MASSIVE BLEEDING

Sibylle A. Kozek-Langenecker, Vienna, Austria

Pär I. Johansson, Copenhagen, Denmark

> W O R K S H O P

CELL SALVAGE FOR THE INEXPERIENCED—AN OVERVIEW OF THE AVAILABLE TECHNOLOGIES

Dafydd Thomas, Swansea, Wales, UK

Jens Meier, Linz, Austria

14:30-14:50 New Oral Anticoagulants: An UpdateMarcel Levi, Amsterdam, The Netherlands

14:50-15:10 Specific and Non-Specific Reversal of Target-Specific Oral AnticoagulantsDavid Faraoni, Boston, MA, USA

15:10-15:30 Viscoelastic Methods (TEG and ROTEM): Have We Progressed?Beverley J. Hunt, London, UK


16:00-16:30 Break

PRO/CON DEBATE: USING A FIXED RBC:FFP:PLT RATIO IN MASSIVELY BLEEDING PATIENTSJens Meier, Linz, Austria • Ivan Čundrle, Brno, Czech Republic

(No parallel session)16:30-16:50 Pro: A 1:1:1 Ratio Should Be UsedPär I. Johansson, Copenhagen, Denmark

16:50-17:10 Con: A 1:1:1 Ratio Is UselessSibylle A. Kozek-Langenecker, Vienna, Austria

17:10-17:30 Discussion

17:30-17:45 Concluding CommentsJean-François Hardy, Montreal, QC, Canada • Charles-Marc Samama, Paris, France

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Blood Transfusion Services / Risks of TransfusionP1

Impact of Demographic Changes in Portugal by 2030 on Blood Donation at São João Blood BankC. Vaz, F. Vasconcelos, M. Koch, M. Carvalho, C. Neves & F. Araújo Department of Transfusion Medicine and Blood Bank, Centro Hospitalar de São João, E.P.E., Porto, Portugal

P2

Awareness of Blood Donation in the Saudi Population: Current Situation and Future DirectionsH. Alsulami & H. AlhatrashiAl Hammadi Hospital Al-Olaya (AAH), Riyadh, Saudi ArabiaP3Optimizing Apheresis Donor Scheduling: An Effective Approach to Increasing Platelet CollectionsP. Lokhandwala, H. Shike, R. Domen & M. GeorgePennsylvania State University Hershey Medical Center and College of Medicine, Hershey, PA, USA

P4

Hepcidin/Ferritin Ratio Correlates with Recovery from Iron Loss Following Blood DonationR. Lotfi1,2, C. Kroll2, D. Plonné3, B. Jahrsdörfer1,2 & H. Schrezenmeier1,2

1Institute for Transfusion Medicine, University of Ulm, Ulm, Germany; 2Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Services Baden-Wuerttemberg-Hessen, Ulm, Germany; 3MVZ Humangenetik Ulm, Abteilung Laboratoriumsmedizin, Ulm, Germany

P5

Abstract withdrawn

P6

Information Technology in Haemostasis and Transfusion in BelarusE. V. Dashkevich, O. V. Krasko, M. S. Rudz & O. N. BondarukThe Republican Research Centre of Transfusion and Medical Biotechnology of Ministry of Health, The State Scientific Institution “The United Institute of Informatics Problems of the National Academy of Sciences of Belarus”, Minsk, Republic of Belarus

P7

Abstract withdrawnP8Platelet Haemostatic Activity Falls in Stored Platelet ConcentratesE. V. Roitman1, I. M. Kolesnikova2 & S. A. Roumiantsev1,2

1Pirogov Russian National Research Medical University, Moscow, Russia; 2Federal Scientific and Clinical Centre on Paediatric Haematology, Oncology and Immunology n.a. D.Rogachev, Moscow, Russia

P9

Decline of Cell Number and Cellular Properties of Blood-banked Red Blood Cells of Different Cell Ages during StorageW.-W. Tuo, D. Wang, W.-J. Liang & Y.-X. HuangDepartment of Biomedical Engineering, Ji Nan University, Guang Zhou, China

P10

Autologous Transfusion of Stored Red Blood Cells Increases Pulmonary Artery PressureR. Pinciroli, L. Berra, C. Mietto, B. Yu, M. Sherrer-Crosbie, C. Stowell & W. M. ZapolDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA

P11

Frozen Platelets – New Challenge and Progressive Alternative in the Blood Component SupplyM. Bohonek, M. Koranova, L. Landova, E. Staskova & E. SladkovaDepartment of Haematology and Blood Transfusion, Central Military Hospital, Military University Hospital, Prague, Czech Republic

Transfusion PracticeP12

Written Informed Consent for Blood Transfusion Could Improve Compliance with Valid Consent ProcessH. Qureshi, P. Sharp, F. Waller, M. Browett, M. Chambers & J. ReidDepartment of Transfusion Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK

Poster Visits 16th Annual NATA Symposium Posters

THURSDAY, APRIL 16 POSTERS # 1-27

10:30-11:00

POSTERS # 1-3 - R. Moog (Germany) & Z. Gašová (Czech Republic)

POSTERS # 4, 6, 8 - J. Stensballe (Denmark) & J. A. García-Erce (Spain)

POSTERS # 9-11 - L. T. Goodnough (USA) & J. Lacroix (Canada)

POSTERS # 12, 17-1 - T. Frietsch (Germany) & J. Cermak (Czech Republic)

POSTERS # 20, 22, 23 - S. R. Leal-Noval (Spain) & K. Cvachovec (Czech Republic)

POSTERS # 24-27 - J. Meier (Austria) & E. Hansen (Germany)

THURSDAY, APRIL 16 POSTERS # 28-57

16:00-16:30

POSTERS # 28-30 - R. Moog (Germany) & Z. Gašová (Czech Republic)

POSTERS # 31-34 - J. L. Carson (USA) & C. So-Osman (The Netherlands)

POSTERS # 35-37 - H. Gombotz (Austria) & K. Cvachovec (Czech Republic)

POSTERS # 38-40 - E. Bisbe (Spain) & H. V. New (UK)

POSTERS # 41-43 - D. Thomas (UK) & J. Meier (Austria)

POSTERS # 44-47 - D. Faraoni (USA) & J. V. Llau (Spain)

POSTERS # 48, 50, 51 - S. A. Kozek-Langenecker (Austria) & J.-F. Hardy (Canada)

POSTERS # 52-54 - P. Van der Linden (Belgium) & Y. Ozier (France)

POSTERS # 55-57 - M. Muñoz (Spain) & I. Čundrle (Czech Republic)

FRIDAY, APRIL 17 POSTERS # 59-91

10:30-11:00

POSTERS # 59-61 – T. Richards (UK) & So-Osman (The Netherlands)

POSTERS # 62-64 – C. Breymann (Switzerland) & J. Cermak (Czech Republic)

POSTERS # 65-67 – P. Van der Linden (Belgium) & T. Frietsch (Germany)

POSTERS # 68, 69, 71 – C.-M. Samama (France) & D. Faraoni (USA)

POSTERS # 72-74 – J. V. Llau (Spain) & S. A. Kozek-Langenecker (Austria)

POSTERS # 75-78 – C. von Heymann (Germany) & H. V. New (UK)

POSTERS # 79, 81, 83, 84 – P. Johansson (Denmark) & V. Černý (Czech Republic)

POSTERS # 85-88 – B. J. Hunt (UK) & P. Salaj (Czech Republic)

POSTERS # 89-91 – M. Levi (The Netherlands) & J. Stensballe (Denmark)

FRIDAY, APRIL 17 POSTERS # 58, 92-101

16:00-16:30POSTERS # 58, 92-94 – C.-M. Samama (France) & J. Stensballe (Denmark)

POSTERS # 95-98 – B. J. Hunt (UK) & P. Johansson (Denmark)

POSTERS # 99-101 – M. Levi (The Netherlands) & P. Salaj (Czech Republic)

nata 2015 14 nata 2015 15

P13-P16

Abstract withdrawn

P17

Differential Transfusion Triggers Obey Biologic Variability in Elderly Recipients U. Nydegger, P. Medina Escobar, L. Risch & M. RischLabormedizinisches Zentrum Dr. Risch, Bern-Liebefeld, Switzerland

P18

Extracorporeal Membrane Oxygenation Therapy and Red Blood Cells TransfusionV. Guilló, P. Castelló, M. Ortega, A. Blanco, S. Arango & A. PeralHospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain

P19

High-dose Chemotherapy Does Not Increase Total Blood Requirements in Patients with Acute Leukaemia during Disease Process: A Nationwide Database StudyJ.-S. Lin & T.-J. ChiouDivisions of Transfusion Medicine and Haematology, Department of Medicine, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC

P20

Overview of Annual Usage of Cellular Blood Components in a Norwegian University HospitalA. Espinosa, F. Rekstad, M. Petersen, B. Sletta & B. Dybvik St. Olav’s University Hospital, Trondheim, Norway

P21

Abstract withdrawn

P22

Platelet Consumption, Indications, Transfusion Triggers and Response to Treatment in Hospital Wards in TehranM. Zadsar1, M. Nasserani Pour2, A. Chegini3, A. Lotfi4 & M. Mojtabavi Naeeni51High Institute of Education and Research on Transfusion Medicine, Research Centre, Tehran, Iran

P23

Decisive Factors about Transfusing Standard or High Doses of Platelets in Daily Clinical PracticeS. Montesdeoca1, M. López2, A. Senin1, M. Ferraro1, E. Johansson1 & C. Besses1

1Department of Clinical Haematology, 2Blood Transfusion Service, Hospital del Mar, Barcelona, Spain

P24

The Reasons for Blood Transfusion OveruseR. Rahav, C. Suriu, L. Akria, M. Barhoum & A. BraesterHaematology Institute, Galilee Medical Centre, Nahariya, Israel

P25

Two-unit Transfusion PracticeC. Donohue, A. Li & S. MallettRoyal Free NHS Foundation Trust, London, UK

P26

Variance in Transfusion Practice in the Era of Patient Blood Management – a UK Multicentre Collaborative StudyM. S. Brar1, L. Ogilvie2, T. Richards3 & A. A Klein2, on behalf of the Association of Cardiothoracic Anaesthetists (ACTA)1London School of Hygiene and Tropical Medicine, London, UK; 2Papworth Hospital, Cambridge, UK; 3University College Hospital, London, UK

P27

Evaluation of Perioperative Crossmatch and Transfusion PracticesA. Fleischer, M. Wittmann, J. Hoch, O. Boehm & G. BaumgartenDepartment of Anaesthesiology and Intensive Care, University Hospital Bonn, Bonn, Germany

P28

Pennine Acute Trust’s Initiatives on Blood WastageA. Allameddine, H. Morris, D. Curley, S. Flynn, M. Heaton & H. JenkinsThe Pennine Acute Trust, Manchester, UK

P29

Project for Quality Improvement 2014: “Measures to Reduce Blood Component Expiration Rate of at Huesca Sector” – Preliminary DataJ. A. Garcia-Erce1,2, B. Menendez, S. Gómez, M. Borrel, M. Cebollero, A. Lezaun & J. J. MarcoHaematology &Transfusion Service, Hospital San Jorge, Huesca, Spain; 1GIEMSA-AWGE, Spain; 2IdiPAZ49, Spain

P30

Improving Orthopaedic Blood Transfusion Practice in a UK Teaching HospitalJ. W. Lim1, Z. Y. Tew1, L. R. Johnston2 & C. Connolly3

1Medical Students; 2Audit Department - Department of Orthopaedic & Trauma Surgery; 3Department of Anaesthesia, Ninewells Hospital and Medical School, Dundee, Scotland, UK

P31

Impact of Individual Physician Blood Reports and “1 vs. 2 Unit” Metric to Lower Red Blood Cell TransfusionsN. Tabesh1, J. DeLisle1, J. Shelby2, D. Oseland1 & K. E. Puca1

1Blood Center of Wisconsin, Milwaukee, WI, USA; 2Wheaton Franciscan Healthcare-All Saints, Racine, WI, USA

P32

100% Compliance to Blood Transfusion Policy Reduces the Use of Blood SignificantlyA. van Gammeren, M. Haneveer, M. Huisman-Ebskamp & R. SlappendelAmphia Hospital, Clinical Chemistry and Hematology, Breda, The Netherlands

P33

The Impact of Single-unit Transfusion Policy on Pennine Acute Trust Blood UsageA. Allameddine, M. Heaton, H. Jenkins, S. Andrews, B. Sedman, C. Porada, & H. Morris The Pennine Acute Trust, Manchester, UK

P34

Evaluation of an Educational Intervention in Transfusion Medicine for Medical Students and Postgraduate TraineesN. Cancellere1, S. Fabra1, A. M. Martinez-Virto1, S. Gómez-Ramirez3, J. A. García-Erce2 & M. Quintana- Díaz1

1Emergency Department, University Hospital La Paz, Madrid, Spain; 2Haematology, General Hospital San Jorge, Huesca, Spain; 3Transfusion Medicine, School of Medicine, University of Málaga, Spain

Blood Conservation Strategies / Autologous TransfusionP35

“Patient Blood Management Italy”: the Italian Pathway towards Interdisciplinary and Multimodal Blood Conservation StrategiesG. M. Liumbruno, S. Vaglio, G. Marano, S. Pupella & G. GrazziniItalian National Blood Centre, National Institute of Health, Rome, Italy

P36

Are Hospitals Implementing a Patient Blood Management Programme?P. Castelló, V. Guilló, M. Ortega, S. Arango, A. Blanco & A. PeralPuerta de Hierro Hospital of Majadahonda, Madrid, Spain

P37

Patient Blood Management Programme: An Effective Strategy in a Third Level HospitalA. Blanco Coronil, V. Guillo Moreno, P. Castello Mora, M. Ortega Gil, M. Aymerich de Franceschi, S. Arango Uribe & A. I. Peral GarcíaHospital Puerta de Hierro Majadahonda, Madrid, Spain

P38

Room for Improvement – Patient Blood Management in Orthopaedic PatientsC. Donohue & S. MallettRoyal Free Hospital, London, UK

P39

Implementation of a Patient Blood Management Programme in Knee ArthroplastyM. Ortega Gil, P. Castelló Mora, V. Guilló Moreno, S. Arango Uribe, A. Blanco Coronil & A. Peral GarcíaHospital Puerta de Hierro Majadahonda, Madrid, Spain

P40

Implementation of a Patient Blood Management Programme in Paediatric Scoliosis SurgeryA. Perez-Ferrer, E. Gredilla, J. de Vicente-Sanchez, J.A. García Erce & F. GilsanzLa Paz University Hospital, Madrid and San Jorge Hospital, Huesca, Spain

Posters 16th Annual NATA Symposium

nata 2015 16 nata 2015 17

P41

Successful Consecutive Pancreatectomies in Jehovah’s Witness PatientsJ. -O. Lee1, D. Choi1, K. Geun Lee1, H. Park1, H. Kim1 & M. A. Jeong2

1Department of Surgery, Hanyang University Hospital, Seoul, Korea; 2Department Anaesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea

P42

Impact of a Transfusion-free Programme on Patients Undergoing PancreaticoduodenectomyY. B. Jeon1, S. Yun1, S. Y. Ok2, J.-W. Koh3 & D. Choi41Department of Surgery, Soonchunhyang University College of Medicine, Seoul, Korea; 2Department of Anaesthesiology, Soonchunhyang University College of Medicine, Seoul, Korea; 3Department of Obstetrics and Gynaecology, Inje University Ilsan Paik Hospital, Ilsanseo-gu, Goyangsi, Gyeongigo, Korea; 4Department of Surgery, Hanyang University College of Medicine, Seoul, Korea

P43

Patient Care Procedures for People Refusing Treatment with Blood DerivativesJ. M. Esparza Miñana, E. Romero, M. Belaouchi & C. GarciaHospital de Manises, Valencia, Spain

P44

Postoperative Use of Autotransfusion Drainage System in Cardiac Surgery PatientsE. Ambarkova Vilarova, T. Anguseva, N. Hristov & Z. MitrevSpecial Hospital “Filip Vtori”, Skopje, Macedonia

P45

Characteristics and Quality of Intraoperative Cell Salvage in Paediatric Scoliosis SurgeryA. Perez-Ferrer, E. Gredilla, J. de Vicente-Sanchez, R. Navarro-Suay, J.A. García Erce & F. GilsanzLa Paz University Hospital and Gomez Ulla Hospital, Madrid, Spain; San Jorge Hospital, Huesca, Spain

P46

Fat Removal during Cell Salvage – Comparison of Devices and ProgrammesT. Seyfried, L. Haas, M. Gruber & E. HansenDepartment of Anaesthesiology, University Hospital Regensburg, Regensburg, Germany

P47

Development of a Surgical Swab Washing DeviceS. Haynes, J. Corden & M. JameelUniversity Hospital of South Manchester, Manchester, UK; TrusTech, Manchester, UK; University Hospital of Wrightington, Wigan and Leigh, Wigan, UK

Anaemia Effects and ManagementP48

Anaemia Management Service: The First Pillar of Patient Blood ManagementA. Allameddine, M. Heaton, H. Jenkins, H. Morris, S. Andrews, B. Sedman, C. Porada & S. FlynnThe Pennine Acute Trust, Manchester, UK

P49

Abstract withdrawn

P50

Preoperative Anaemia in Colorectal SurgeryJ. Gudaitytė1,2, E. Šalčiūtė2,3 & V. Šaferis4

1Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania; 2Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania; 3Vilnius University, Faculty of Medicine, Vilnius, Lithuania; 4Department of Mathematics, Physical and Biophysical Sciences, Lithuanian University of Health Sciences, Kaunas, Lithuania

P51

Preoperative Haemoglobin Concentration, Cardiopulmonary Exercise Testing and Postoperative OutcomeJ. M. Otto1, A. F. O’Doherty2, R. S. Moonesinghe3,6, R. C. M. Stephens3, D. S. Martin4; H. E. Montgomery5 & T. Richards1

1Division of Surgery and Interventional Science, University College London, London, UK; 2Department of Sport, Health and Exercise Science, University of Hull, Hull, UK; 3Centre for Anaesthesia, 3rd Floor Maple Link Corridor, University College London Hospital, London, UK; 4Divisional of Surgery and Interventional Science, Royal Free Hospital, University College London, London, UK; 5Institute for Human Health and Performance, University College London, and NIHR University College London Hospitals Biomedical Research Centre, London, UK; 6Surgical Outcomes Research Centre (SOuRCe), University College London Hospital, London, UK

P52

Anaemia and Patient Blood Management Implementation in Liver TransplantationB. Clevenger, T. Richards & S. V. MallettRoyal Free Hospital, London, UK

P53

Preoperative Optimisation of Anaemic Patients: A Task to Reduce Blood Transfusions at Puerta de Hierro Hospital in MadridS. Arango, M. Ortega, V. Guilló, P. Castelló, A. Blanco & A.I. PeralHospital Universitario Puerta de Hierro, Madrid, Spain

P54

An Intravenous Iron Based Protocol for Optimising Haemoglobin in Anaemic Patients Prior to Fast Track Hip and Knee Arthroplasty – An Observational Follow Up StudyO. Jans & H. Kehlet Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark

P55

A Pragmatic Clinical Use of the Ferric Carboxymaltose Tool: Pre-surgical Treatment of Anaemic or Iron Deficiency in Patients with Colorectal NeoplasmL. E. Gutiérrez Cantero1, S. García Orallo2 & J. Rodríguez García3

1Surgery Department, 2Anaesthesiology Department, 3Infection-Epidemiology Department, Sierrallana Hospital, Torrelavega, Spain

P56

Clinical Response to Preoperative Intravenous Administration of Ferinject®: A Portuguese Observational, Retrospective, Multicentre StudyJ. Martinez1 & C. Aldeia2

1Serviço de Imuno-Hemoterapia, Centro Hospitalar Cova da Beira, Fundão, Portugal; 2Serviço de Imuno-Hemoterapia, Hospital do Litoral Alentejano, Santiago do Cacém, Portugal

P57

Patient Recruitment for PREVENTT, a Preoperative Anaemia Trial: Single Centre ExperienceH. Lawrence, K. Horner, M. Koutra, E. Black, E. Todman, S. Jhanji & R. Rao BaikadyThe Royal Marsden NHS Foundation Trust, London, UK

P58

Case Presentation – Inadvertent Extravasation of Ferric Carboxymaltose (Ferinject) SolutionM. Thomas, J. Faulds, C. Ralph & S. StaddonRoyal Cornwall Hospitals NHS Trust, Cornwall, England, UK

P59

Anaemia after Colorectal Cancer Surgery: Prevalence and Pattern of Use of Iron TreatmentsM. J. Laso, A. Vallejo, R. Vives, I. Roig, M. Barquero & C. PontesHospital de Sabadell, Institut Universitari Parc Taulí, Universitat Autònoma de Barcelona, Spain

P60

Iron Deficiency and Intravenous Iron Therapy after Major Cancer SurgeryH. Lawrence, S. Cleland, J. Benham, E. Todman & R. Rao BaikadyThe Royal Marsden NHS Foundation Trust, London, UK

P61

Feasibility and Efficacy of a Clinical Protocol Using Intravenous Iron for Treating Iron Deficiency Anaemia at the Emergency DepartmentM. Quintana Díaz1, S. Fabra1, S. Gómez-Ramirez3, J.A. García-Erce2 & M. Muñoz3

1Emergency Department, University Hospital La Paz, Madrid; 2Haematology, General Hospital San Jorge, Huesca; 3Transfusion Medicine, School of Medicine, University of Málaga, Málaga, Spain

P62

Intravenous Ferric Carboxymaltose for Iron Deficiency or Iron Deficiency Anaemia in Pregnancy: An Updated Cohort StudyB. Froessler1,4, C. Bunn1, N. Hodyl3 & G. Dekker2 1Department of Anaesthesia, 2Department of Obstetrics & Gynaecology, Lyell McEwin Hospital, Elizabeth Vale; 3School of Paediatrics and Reproductive Health Robinson Research Institute, 4Acute Care Medicine, University of Adelaide, South Australia

P63

Establishing an Iron Infusion Service in a Specialist Cancer Treatment CentreS. Cleland, H. Lawrence, J. Benham, E. Todman & R. Rao BaikadyThe Royal Marsden NHS Foundation Trust, London, UK


nata 2015 18 nata 2015 19

P64

Comparative Cost-Efficacy of Four Intravenous Iron Formulations for Treating Inflammatory Bowel Disease Associated Anaemia: An Estimation from Published Data S. Gómez-Ramírez1, J. Pavía2, E. Martín-Montañez2 & M. Muñoz3 1Internal Medicine, Xanit International Hospital, Benalmádena, Málaga; 2Pharmacology and 3Transfusion Medicine, School of Medicine, University of Málaga, Málaga, Spain

Fluid Therapy / Oxygen CarriersP65

Cerebrovascular Response to Infusion of EAF P5K6-Alb, NO Producing, Colloidal Plasma Volume Expander, is Muted in Transgenic Mouse Models of Sickle Cell DiseaseC. A. Branch, M.-H. Cui, H. Billet & S. AcharyaAlbert Einstein College of Medicine, Bronx, NY, USA

Haemostasis & ThrombosisP66

Lineal Multiple Regression Model to Predict Intraoperative Blood Loss during Paediatric Orthotopic Liver TransplantationJ. De Vicente, A. Perez-Ferrer, G. Campo, R. Perez-Gonzalez & F. GilsanzLa Paz Paediatric University Hospital, Madrid, Spain

P67

The Effect of Intraoperative Low Dose Epinephrine Infusion on Bleeding during Total Hip Arthroplasty – A Double-blinded Placebo-controlled Randomised TrialO. Jans1, U. Grevstad2, H. Mandøe3, H. Kehlet1 & P. I. Johansson4

1Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark; 2Department of Anaesthesia, Gentofte Hospital, Gentofte, Denmark; 3Department of Anaesthesia, Vejle Hospital, Vejle, Denmark; 4Department for Transfusion Medicine, Rigshospitalet, Copenhagen, Denmark

P68

Multicentre, Randomised Placebo-Controlled Clinical Trial to Evaluate the Effect of Perioperative Use of Tranexamic Acid on Transfusion Requirements and Surgical Bleeding in Major Spine SurgeryL. Mora1, MJ. Colomina1, E. Ciércoles1, E. Guerrero1, I. Otero2, A. Pi2, M. Basora3 & C. Garcia4

1Anaesthesia Department, Hospital Universitari Vall d’Hebron, Barcelona, Spain; 2Anaesthesia Department, Hospital Universitari Bellvitge, Barcelona, Spain; 3Anaesthesia Department, Hospital Clínic, Barcelona, Spain; 4Anaesthesia Department, Hospital de Getafe, Madrid, Spain

P69

Tranexamic Acid Reduces Transfusion Requirements in Adult Major Spine SurgeryJ.-F. Hardy, Q. Wu, V. Brulotte, D. Boudreault, M. Ruel & P. Bodson-ClermontDepartment of Anesthesiology and Research Center of the CHUM, Montreal, Quebec, Canada

P70

Abstract withdrawn

P71

Maximal Amplitude Measured by Thromboelastography (TEG®) May Be a Better Predictor of Bleeding than Total Platelet Count in Haematological Malignancy Patients with Thrombocytopenia: A Pilot Observational StudyR. Kasivisvanathan1, M. Koutra1, M. Rooms1, E. Black1, L. Desai1, S. V. Mallett2 & R. Rao Baikidy1

1Department of Anaesthesia, The Royal Marsden NHS Foundation Trust, London, UK; 2Department of Anaesthesia, The Royal Free NHS Foundation Trust, London, UK

P72

Thromboelastometry (ROTEM)-guided Diagnosis and Therapy of Coagulopathy Reduces Fresh Frozen Plasma Consumption Compared with Prothrombin Time–INRM. Durila1, P. Lukáš1, M. Astraverkhava1, J. Beroušek1, E. Linhartová2 & T. Vymazal11Department of Anaesthesiology and Intensive Care Medicine, 2Blood Bank Department, Second Faculty of Medicine, Charles University in Prague, Motol University Hospital, Prague, Czech Republic

P73

Acute Coagulopathic Bleeding in Perioperative Setting: Development of an Interventional AlgorithmM. Gomes1, A. Rodrigues2, M. Carvalho3, A. Carrilho4, A. Robalo Nunes5, R. Orfão6, A. Alves7, J. Aguiar8 & M. Manuel Campos9

1SIH, HHTMM, Lisboa, Portugal; 2S.Imuno-Hemoterapia(IH), H. Sta Maria (HSM), CHLN, Lisboa, Portugal; 3SIH, H. S. João, CHSJ, Porto, Portugal; 4S. Anestesia (SA), H. S. José, CHLC, Lisboa, Portugal; 5SIH, H. P. Valente, CHLN, Lisboa, Portugal; 6SA, CHUC, Coimbra, Portugal; 7SA, HSM, CHLN, Lisboa, Portugal; 8SA, H. Sto António (HSA), CHP, Porto, Portugal; 9S. Hematologia Clinica, HSA, CHP, Porto, Portugal

P74

Transfusion Practices and Outcomes of Massive Blood Loss during Oncosurgery in a Tertiary Cancer HospitalN. Amin, V. Agarwal & V. P. PatilAnaesthesiology, Critical Care and Pain, Tata Memorial Centre, Mumbai, India

P75

Validation of Multiplate® Impedance Aggregometry and Evaluation of Local Reference ValuesJ. Dhillon, L. Oomen, A. Ahmed & H. QureshiDepartment of Transfusion Medicine, University Hospitals of Leicester NHS Trust, Glenfield Hospital Leicester, UK

P76

Introduction of a Platelet Mapping Service May Reduce Inappropriate Platelet Transfusion in Cardiac SurgeryK. Abass1, C. Sathananthan2, J. van der Kaaij1, & D. Farrar1

1Department of Anaesthesia, The Heart Hospital, University College London Hospitals NHS Foundation Trust, London, UK; 2Department of Anaesthesia, University, College London Hospitals NHS Foundation Trust, London, UK

P77

Fibrinogen Concentrate Administration during Complex Cardiac Surgery: Results from the São João University Hospital during 2014L. Gonçalves1, A. Freixo1, H. Gomes1, C. Vaz1, F. Vasconcelos1, J. Casanova2 & F. Araújo1

Transfusion Medicine Department1, Cardiac Surgery Department2, São João University Hospital, Porto, Portugal

P78

Influence of Factor XIII Levels on Clot Firmness during Major Paediatric SurgeryT. Haas1, N. Spielmann1, M. Cushing2, M. Schmugge3 & M. Weiss1

1Department of Anaesthesia, University Children’s Hospital Zurich, Switzerland; 2Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; 3Department of Haematology, University Children’s Hospital Zurich, Switzerland

P79

Implementation of a Perioperative Thromboelastometry-guided Transfusion Algorithm for Cardiac Surgery Reduces Transfusion and Increases Number of Patients without any TransfusionT. Frenzel1, D. M. Rotteveel-de Groot2; E. C. van Pampus3; N. Horn4; L. Noyez5 & J. G. van der Hoeven1

1Department of Intensive Care Medicine, 2Department of Laboratory Medicine, 3Laboratory of Medical Immunology, 4Department of Anaesthesiology, 5Department Thoracic and Cardiac Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands

P80

Abstract withdrawn

P81

A Retrospective Audit of the Massive Transfusion Protocol Activation in Tan Tock Seng Hospital (TTSH), SingaporeH. Toh, H. G. See & J. E. J. TanDepartment of Anaesthesiology, Intensive Care and Pain Medicine, Tan Tock Seng Hospital (TTSH), Singapore

P82

Abstract withdrawn

P83

Impaired Coagulation Control Mechanisms in Trauma Patients with Disseminated Intravascular Coagulation at an Early Phase of Trauma S. Gando, A. Sawamura, M. Hayakawa, T. Wada, J. Yanagida, D. Miyamoto, K. Maekawa, Y. Ono, K. Katabami & A. MizugakiDivision of Acute and Critical Care Medicine, Department of Anaesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan


nata 2015 20 nata 2015 21

P84

Effects of Implementation of Damage Control Resuscitation Practices: From Massive Transfusion Protocol (MTP) to Thromboelastometry (ROTEM®)-based Transfusion AlgorithmM. Barquero LópezCorporació Sanitària Universitària Parc Taulí, Sabadell, Spain

P85

Transfusion Requirements: Analysis Before and After the Introduction of Trombelastometry Guided Factor Concentrate Based Algorithm for the Therapy of Coagulopathy in Massive BleedingI. Zýková, P. Sedlák & D. MormanAnaesthesia and Intensive Care Department, Regional Hospital Liberec, Liberec, Czech Republic

P86

Thrombelastography and Functional Fibrinogen Reference Ranges in Healthy Full Term Pregnant WomenL. Eastwood, R. Mitha, K. Pendry, J. Thachil & P. KochharCentral Manchester University Hospitals NHS Foundation Trust, Manchester, UK

P87

Blood Loss Auto-Monitoring and Estimation in Early Puerperium Using a Pictorial MethodS. Xodo, G. Straface & V. ZanardoPoliclinico Abano Terme, Abano Terme, Italy

P88

When the Bleeding Does Not Stop – How Do We Transfuse Obstetric Patients?J. Fonseca, S. Mota, I. Cunha, C. Alves & J. CarvalhasUniversity Hospital of Coimbra, Maternidade Dr. Daniel de Matos, Coimbra, Portugal

P89

Massive Obstetric Bleeding – Effective Multidisciplinary ApproachS. Mota, J. Fonseca, R. Cabral, S. Marques, C. Alves, M. Gil Pereira & J. CarvalhasDepartment of Anaesthesiology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal

P90

Treatment of Disseminated Intravascular Coagulation Caused by Amniotic Fluid EmbolismJ. Mannova & P. LonginDepartment of Anaesthesia and Resuscitation, Hospital Havlickuv Brod, Havlickuv Brod, Czech Republic

P91

Is Prothrombin Complex Concentrate Used Adequately? Is Coagulopathy Correction Achieved? Our ExperienceR. Castellanos-González, H. Pérez-Domínguez, D. Calles-Gato, E. Chica, L. De la Cruz-Alvarado & C. García-MolinaDepartments of Anaesthesiology and Haematology, Hospital Universitario de Getafe, Madrid, Spain

P92

Experience in the Use of Prothrombin Complex Concentrate for Reversal of Apixaban Induced BleedingM. Estébanez1, A. M. Borobia1,2, J. A. García-Erce3, A. M. Martínez-Virto1 & M. Quintana-Díaz1

1Emergency Department, La Paz University Hospital of Madrid, IdiPAZ ; 2Clinical Pharmacology Department, La Paz University Hospital of Madrid, IdiPAZ, Spain; 3Haematology Department, San Jorge Hospital of Huesca, IdiPAZ, Spain

P93

High Versus Low Protamine-to-heparin Dosing Ratio Following Cardiopulmonary Bypass: A Multicentre Randomised Controlled TrialM. I. Meesters, D. Veerhoek, L. J. M. van Barneveld, F. de Lange, J. W. de Vries, J. W. A. Romijn, A. B. A. Vonk & C. BoerDepartments of Anesthesiology and Cardio-thoracic Surgery, VU University Medical Centre, Amsterdam, the Netherlands; Department of Anaesthesiology Medical Centre Leeuwarden, Leeuwarden, The Netherlands

P94

Plasma Concentration of Tissue Factor (TF) and Tissue Factor Pathway Inhibitor (TFPI) in Patients with Morbid ObesityA. Firszt-Adamczyk1, P. Adamczyk2, R. Szafkowski2, M. Firszt3, I. Ponikowska2, I. Iwan-Ziętek4, B. Góralczyk1, B. Ruszkowska-Ciastek1 & D. Rość1 1Department of Pathophysiology Collegium Medicum, Bydgoszcz, Poland; 2Clinic of Balneology and Physical Medicine, Nicolaus Copernicus University, Toruń, Collegium Medicum in Bydgoszcz, Poland; 3Faculty of Mathematics and Computer Science, Nicolaus Copernicus University, Toruń, Poland; 4Department of Dermatology and Venerology, Pomeranian Medical University, Szczecin, Poland

P95

Thromboembolic Events and Thromboprophylaxis in Major Spinal Deformity SurgeryL. Mora1, M. J. Colomina1, A. Vila-Casademunt2, E. Ciércoles1, E. Guerrero1, J. Bagó3, F. Pellisé3 & European Spine Study Group1Vall d´Hebron University Hospital, Department of Anaesthesiology, Barcelona, Spain; 2Vall d´Hebron University Hospital, Research and Development Department, Barcelona, Spain, 3Vall d´Hebron University Hospital, Department of Surgery, Barcelona, Spain

P96

Fondaparinux Monitoring in a Dialysis Patient with Heparin-induced Thrombocytopenia Type IIA. Kulić1, V. Libek1, A. Strugar1, Z. Cvetković2, & R. Marković3

1Blood Bank Department, CHC Zemun, Belgrade, Serbia; 2Department of Haematology, CHC Zemun, Belgrade, Serbia; 3Departments of Nephrology and Dialysis, CHC Zemun, Belgrade, Serbia

P97

Thrombotic Microangiopathies: Transfusion Management of Three Case ReportsM. M. Campos, V. Pishchanskyy, M. E. Ribeiro, M. J. Marques, A. Fernandes, A. E. Silva & T. AraújoImmunohaemotherapy (Head of Department: D. Espírito Santo), Hospital Curry Cabral (HCC), Centro Hospitalar Lisboa Central, EPE, Lisbon, Portugal

P98

Management of Prosthetic Valve Thrombosis during PregnancyK. Schulte1,2, R. Attia1, X. Luo1 & V. Bapat1

1Department of Cardiothoracic Surgery, Guy’s and St Thomas’ Hospital, London, UK; 2Charité Berlin, Germany

P99

Tissue Factor and the Risk of Thrombosis in Patients with Polycythemia VeraG. Gadomska1, J. Boinska1, K. Stankowska1, M. Michalska1, K. Góralczyk1, R. Wieczór1, B. Ruszkowska-Ciastek1 & D. Rość1

1Department of Pathophysiology Collegium Medicum, Bydgoszcz, Poland; 2Clinic of Haematology and Haematological Malignancies Diseases, Dr J. Biziel University Hospital No. 2, Bydgoszcz, Poland

P100

Maternal Genetic Risk Factors of Thrombophilia: 1691G>A FV, 20210G>A FII, 677C>T MTHFR Mutations and Recurrent Pregnancy Loss in Bosnian WomenG. Adler1, E. Mahmutbegovic2, A. Valjevac3, A. Pawinska-Matecka4, A. Garstka1, A. Begovic 1 & E. Czerska4

1Department of Gerontobiology, Pomeranian Medical University, Szczecin, Poland; 2Institution of Health Protection of Women and Motherhood Canton Sarajevo, Sarajevo, Bosnia and Herzegovina; 3Laboratory for Molecular Medicine, Center for Genetics, Medical Faculty, University of Sarajevo, Sarajevo, Bosnia and Herzegovina; 4Central Laboratory, Regional Hospital, Szczecin, Poland

P101

Dramatic Decrease of Prothrombin Level during Thrombolysis in Acute Myocardial InfarctionT. M. Platonova1, V. O. Chernyshenko1, D. S. Korolova1, T. M. Chernyshenko1 & O. Parkhomenko2

1Protein Structure and Functions Department, Palladin Institute of biochemistry of NAS of Ukraine, Kyiv, Ukraine; 2National Scientific Center “M.D. Strazhesko Institute of Cardiology MAS of Ukraine”, Kyiv, Ukraine


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NATA PartnersNATA would like to thank the following partners for their significant support in developing its educational activities.

Gold Partner Silver Partners

Lunchtime Sponsored Symposium – Forum HallSupported by Masimo

Latest Strategies in Patient Blood Management: New Monitoring Trends

12:45-12:50 Welcome and IntroductionKai Zacharowski, Frankfurt am Main, Germany

12:50-13:10 Surgical Patients & Anaemia: Patient Blood Management Kai Zacharowski, Frankfurt am Main, Germany

13:10-13:30 Patient Blood Management and Transfusion OptimisationJuan V. Llau, Valencia, Spain

13:30-13:50 The Cambridge Experience: Optimising Transfusion Decisions and Post-op Internal Bleeding DetectionVishal Patil, Cambridge, UK


Lunchtime Sponsored Lectures – Forum HallSupported by Nordic Pharma

12:45-13:05 Aprotinin: Facts and BeliefsChristian von Heymann, Berlin, Germany

13:05-13:25 CABG Patients on Antiplatelet Therapy: Room for Aprotinin? Jan van der Linden, Stockholm, Sweden


THURSDAY, April 16, 2015

Lunchtime Sponsored Lectures – Forum HallSupported by an educational grant from Fresenius Kabi

13:45-14:05 Red Blood Cell Salvage: A Cornerstone of Patient Blood ManagementJens Meier, Linz, Austria


FRIDAY, April 17, 2015

FRIDAY, April 17, 2015

Industry-Sponsored Programme 16th Annual NATA Symposium

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Booth No. 7The British Society of Orthopaedic Anaesthetists (BSOA) is a specialist society for anaesthetists with an interest in Orthopaedic Anaesthesia.The general objects of the Society are to promote for the public benefit research and education in the field of Orthopaedic Anaesthesia, and to that end promote fellowship and professional links between orthopaedic anaesthetists and promote excellence in orthopaedic anaesthetics.

Booth No. 1Fresenius Kabi is a global healthcare company that specializes in lifesaving medicines and technologies for infusion, transfusion and clinical nutrition. The products and services help to care for critically and chronically ill.Product portfolio: I.V. generic drugs, infusion therapies, clinical nutrition and related medical devices, products for whole blood and blood components collection and processing, transfusion medicine and cell therapies.

Booth No. 6Haemonetics (NYSE: HAE) is a global healthcare company dedicated to providing innovative blood management solutions for our customers. Together, our devices and consumables, IT products, and consulting services deliver a suite of business solutions to help our customers improve clinical outcomes and reduce the cost of healthcare for blood collectors, hospitals, and patients around the world. Our technologies address important medical markets: blood and plasma component collection, the surgical suite, and hospital transfusion services. To learn more about Haemonetics visit our web site at http://www.haemonetics.com.

Booth No. 8Masimo Corporation is one of the world’s most admired medical technology companies credited with revolutionizing pulse oximetry and noninvasive patient monitoring. A global medical technology innovator, Masimo has been on the forefront of patient safety and a beacon of innovation

in healthcare for more than 25 years. As the inventor of Measure-Through Motion and Low Perfusion Masimo SET® pulse oximetry—the market-leading pulse oximetry technology solution—and Masimo rainbow® Pulse CO-Oximetry™—a breakthrough noninvasive blood-constituent monitoring platform, Masimo has a portfolio of clinically proven products that lead the way in innovation, performance and patient safety by giving health care providers the information they need to optimize clinical decision-making. In addition, with technology license and OEM agreements with leading patient monitoring manufacturers spanning the globe, Masimo’s advanced oximetry technologies can be found inside of today’s top multiparameter brands, such as Atom, Datascope, GE Medical, Medtronic, Philips, Spacelabs and Zoll, among others.

Booth No. 5At Medtronic (www.medtronic.com), we’re committed to Innovating for life by pushing the boundaries of medical technology and changing the way the world treats chronic disease. Driven by our deep understanding of the human body and our collaboration with physicians, we’re transforming technology to treat patients across the entire care continuum. Our innovations help physicians diagnose diseases earlier, treat patients with the least amount of disruption possible, and help alleviate symptoms throughout the patient’s life. Today, we’re improving the lives of millions of people worldwide each year across numerous conditions - including heart disease, diabetes, neurological disorders, spinal conditions, and vascular diseases. But it isn’t enough. So we’re innovating beyond products. We’re breaking down barriers, challenging assumptions, and looking beyond the status quo - to continually find more ways to help people live better, longer.Medtronic was founded in 1949 as a medical equipment repair company by Earl Bakken and his brother-in-law, Palmer Hermundslie. Today, we’re the world’s largest independent medical technology company. We employ 46,000 people worldwide - serving physicians, clinicians, and patients in more than 140 countries.

Booth Booth No. 4The Nordic Group is a privately owned, fully integrated, pan-European pharmaceutical company with a strong focus on the development and commercialization of niche hospital and orphan products and services that cater to the specific needs of physicians and patients. Nordic Group has a direct sales and marketing presence in 17 European countries, operating under the name of Nordic Pharma and Nordic Drugs. Nordic (which was already marketing an aprotinin product) acquired rights to Trasylol® from Bayer in July 2012, worldwide excluding the United States. Additional information can be obtained at www.nordicpharmagroup.com.

Booth No. 2Sorin Group is a global leader in the treatment of cardiovascular diseases. Committed to blood management for more than 30 years, and operating in more than 80 countries, Sorin Group has treated more than 6.5 million patients with its autotransfusion devices. At NATA, Sorin Group is proud to exhibit Sorin XTRA, its sixth-generation autotransfusion system. Sorin XTRA is a compact, ergonomic, robust autotransfusion device with an attractive design.

Sorin XTRA combines and improves the best features of current Sorin autotransfusion devices, introducing further innovation through C5 and S5-like design, graphic colour touch screen user interface and advanced data management capabilities. To know more about this, please visit our booth.www.sorin.come-mail: [email protected]

Booth No. 3Vifor Pharma is one of the world’s leaders in the discovery, development, manufacturing and marketing of pharmaceutical products for the treatment of iron deficiency. The company also offers a diversified portfolio of prescription medicines as well as over-the-counter (OTC) products. Vifor Pharma, headquartered in Zurich, Switzerland, has an increasingly global presence and a broad network of affiliates and partners around the world. The iron portfolio includes Ferinject® (ferric carboxymaltose), a novel intravenous iron replacement therapy, Venofer® (iron sucrose), the leading intravenous iron product for the treatment of iron deficiency anaemia in renal patients as well as the oral iron Maltofer®.

Sponsors and Exhibitors 16th Annual NATA Symposium

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1 Fresenius Kabi

2 Sorin Group

3 Vifor Pharma

4 Nordic Pharma

5 Medtronic

6 Haemonetics

7 British Society of Orthopaedic Anaesthetists

8 Masimo


I �Blood Transfusion Services / Risks of Transfusion

I �Transfusion Practice

I �Blood Conservation Strategies / Autologous Transfusion

I �Anaemia Effects and Management

I �Fluid Therapy / Oxygen Carriers

I �Haemostasis & Thrombosis

on Patient Blood Management, Haemostasis and Thrombosis

www.nataonline.com

on Patient Blood Management, Haemostasis and Thrombosison Patient Blood Management, Haemostasis and Thrombosis17th ANNUAL NATA SYMPOSIUM

April 14-15 2016 DUBLINMain Auditorium

(Forum Hall)

Workshop Room 1(Terrace I)

Workshop Room 2(Terrace II)

Speakers’

Room(Room 2.3)

NATAOffice

(Room 2.2)

12

7 8

3Exhibition Area

4 65

Exhibition Floor Plan

Prague Congress Centre - Level 2

Fresenius Kabi AGElse-Kroener-Str. 1 61352 Bad Homburg, GermanyPhone: +49 (0) 61 72 686 4913Fax: +49 (0) 61 72 686 [email protected]

Consistently high washout performance makes the

difference in Autotransfusion

Visit us at booth 1

Documents

Annual NATA Symposium on Patient Blood … Promt5 Dear Colleague, On behalf of the NATA board of directors, it is my pleasure to welcome you to the 16th NATA Symposium on Patient Blood