The aim is to revolutionize gas sensing by providing a broadband, compact and robust sensing platform in the mid-infrared range for a wide variety of chemical species.

This leads to industrial on-line and in-line process control, environmental monitoring and potentially enables medical breath analysis and artificial noses.

The vision is that chemical sensing can be pushed to the mid-IR with our broadband platform.

1

Andreas Hugi, Markus Geiser – Semiconductor based

frequency comb spectroscopy: IRsweep

The aim is to establish methods to quantify pathogenic microorganisms in 30-45 min using a cheap and portable device.

This leads to a new device for the rapid and quantitative detection of pathogenic microorganisms which can be also used in field applications.

The vision is that this method and device will become widely used in the food and water industry.

1

Jijo Vallooran – Liquid Crystal cubic phase biosensors for the rapid and facile detection of pathogenic microorganisms.

1

Bryan Anastasiades & Keith Gunura – Wearable assistive posture support

The aim is to develop a wearable assistive posture support for industry workers who have to stand for long periods of time during their work day.

This leads to better working conditions for workers in factories and other labor sectors as well as an increase of productivity for employers

The vision is that we change the way people experience standing by bringing the freedom to sit whenever needed.

The aim is to apply our image processing algorithms to automatically recognize and describe fashion items in images.

This leads to an algorithm that connects fashion products in every digital as well as real-world fashion image to their buyable counterparts.

The vision is that we bridge the gap between seeing and buying fashion products and change the way people shop online.

1

Matthias Dantone, Lukas Bossard : Intelligent Online Shopping Assistant

Martin Ostermaier: InterAx – Tailored arrestins for drug discovery

The aim is to develop a novel arrestin-based drug-screening assay utilizing tailored arrestins

This leads to accessibility of new drug targets and read-outs of higher quality

The vision is that the established assay allows us to screen successfully for lead compounds

The aim is to apply 3- and 4D imaging, analysis algorithms, and report generation towards understanding a wide variety of problems and materials.

This leads to a consulting service where measurements and analysis can be performed on complicated samples with clear reports as a final product.

The vision is to offer customized stand-alone analysis to every microscopy user from cell biologists to petroleum engineers turning pictures to information in one click.

1

Kevin Mader – 4Quant: 3D and 4D Structural Characterization of Complex Materials

The aim is to finish preclinical trials of device safety and efficacy, to finalize the design, surgical approach, device manufacture, and packaging approach.

This leads to the approval for human implantation. Further proof of device safety and efficacy will be documented in human clinical trials.

The vision is that this device is approved for clinical application. With this device, the patient will attain similar healing outcome as with BTB autograft but without donor site morbidity. The surgeon can perform a significantly simpler and faster operation, reducing economic cost, but with improved efficacy.

1

Xiang Li – A novel hybrid construct for anterior cruciate ligament reconstruction: An off-the-shelf alternative to a bone-tendon-bone autograft

Fully featured prototype

The aim is to develop optimal surface micro-structures on biocellulose to promote highly efficient tissue healing and integration of medical devices.

This leads to faster wound closure, improved scar tissue and reduced fibrosis; firstly benefitting to burnt, cardio-assisted and mastoplasty patients.

The vision is that all implantable medical devices and all wound dressings will feature surface micro-structures to enhance their performances.

Simone Bottan – The HyloMorph Project

10 µm

The aim is to provide fast adoption of revolutionary in silico methods for molecular discovery.

This leads to the optimization of R&D routines in life sciences organizations, and provides new vantage points towards molecular modeling, target, and lead identification.

The vision is that lifematics will continuously create value for pharmaceutical research by providing leading edge computer assisted molecular discovery experience with unparalleled performance, speed, ease of use, and success.

1

Nickolay Todoroff – lifematics

The aim is to develop a robust and versatile decontamination therapy based onmicrovesicles able to extract drugs and toxic metabolites from the organism.

This first leads to a emergency countermeasure addressing hyperammonemicnewborns for which conventional therapies (i.e., hemodialysis) are inapplicable.

The vision is that our approach will become the gold-standard to help these neonatesand will be translatable to support the ever-growing number of drug intoxications.

Vincent Forster – Universal antidote for bio-detoxification

The aim is:

To fabricate high-quality micro-sized permanent magnets and integrate them in microsystems.

This leads to:

Advanced magnetic sensors and actuators for various applications.

The vision is that:

New class of permanent magnetic microsystems will be realized with advantages over existing technologies.

1

Olgaç Ergeneman – MAGNES

Arrays of thick (1-100 µm) magnets can be produced by electrodeposition.

Multi-axis sensors or sensor arrays can be realized with this technology.

The aim is to develop and apply a massively parallelized print head, compatible with the breakthrough concept of NanoDrip printing.

This leads to the first ink-jet device capable of fabricating nanostructured devices at ultra-low cost and with great flexibility.

The vision is that that NanoDrip printing becomes a disrupting technology, which not only reduces the cost of current fabrication but enables novel products to emerge, primarily in the area of printed electronics.

1

Patrick Galliker – NanoDrip: Bringing nanoscale printing to industrial devices

The aim is to further develop a time-dependent induced seismicity risk assessment software for applications as deep geothermal energy, waste water and carbon dioxide storage.

This leads to a framework and software tool able to quantify the seismic risk associated to induced seismicity in near-real time. Traffic light systems to mitigate induced seismicity will be provided.

The vision is to support the further development of deep geothermal energy as well as carbon dioxide storage by mitigating the seismic risk with validated methodologies.

1

Delano Landtwing - GeoEnergy Risk Services

The aim is to prototype a compact high throughput sample introduction system (TissueVis) coupled to various types of mass spectrometers for chemical imaging.

TissueVis leads to sub-cellular spatial resolution sampling on biological tissue thin sections as well as an enhanced signal to noise ratio of the protein information.

The vision is that TissueVis based imaging system provides biologists/pathologists/medical doctors better understanding in biological questions and to improve patient classification.

1

H.A.O. Wang – Laser ablation system for sub-cellular tissue imaging – TissueVis

0

500

1000

1500

2000

2500

3000

3500

INTENSITY[cps]

20 µm

MSICP

Inte

rfac

e

UV Laser beamMovement

Sample

Aerosol

TissueVis

165Ho

165Ho

165Ho

The aim is to commercialize the NanoFrazor.

This leads to the possibility for our clients to fabricate complex nanostructures with high speed, high quality at low costs.

The vision is that the NanoFrazor becomes a standard tool for rapid-prototyping of nanostructures in clean rooms all over the world.

1

Felix Holzner – NanoFrazor the new tool for nanofabrication

Picture to illustrate your project…

The aim is to provide automatically generated, highly-optimized software and hardware solvers for optimal decision making on low-resource embedded systems.

This leads to higher efficiency, performance and productivity while enabling radically new applications.

The vision is that by our tools embedded optimization becomes a new technology building block in diverse engineering domains.

1

Stefan Richter and Juan Jerez High-Speed Optimal Decision Making on Embedded Systems

Processaction

Control

SignalProcessing

Optimal Decision Making

information

specification

The aim is to apply our image and video processing algorithms to automatically understand human motion.

This leads to software that can be used to assist rehabilitation and physiotherapy patients with exercises at home.

The vision is to extend rehabilitation and physiotherapy beyond the walls of a traditional healthcare facility.

1

Angela Yao – Vision Based Human Motion Analysis

http://123kinect.com/wp-content/uploads/2013/05/kinect-windows.jpg

http://www.innovationmagazine.com/innovation/volumes/v11n1/images/schoolssection2d.jpg

The aim is to build COOT; a completely automatic C source code to Java source code translator.

This leads to a new possibility for our clients to migrate legacy C projects to a modern programming language.

The vision is that COOT becomes the standard approach in industry for migrating C projects into modern environments.

1

Marco Trudel – COOT: Automatic C to Java translator.

COOT translation: - automatic - fast - correct - high quality - low cost - low risk

The aim is to establish methods to quantify food- and waterborne micro-organisms in under 1 hour by automated on-chip immunomagnetic separation (IMS) and flow cytometric (FCM) detection.

This leads to a dramatic reduction in analysis time, and thus to the prevention of food and water related outbreaks of pathogenic organisms.

The vision is that this method will become an approved standard methods food and drinking water microbiology.

Hans-Anton Keserue – Rapid and quantitative detection of pathogenic microorganisms by flow cytometry

1. Magnetic labeling of target organisms

2. On-chip magnetic separation

3. Benchtop device for automated magnetic separation (aIMS)

4. FCM analysis

Method overview:

© Invitrogen

The aim is to… use a direct measurement principle enabled by MEMS technology to reliably measure the pressure in the vacuum range.

This leads to… the next generation vacuum pressure sensing technology with large operating range and gas type independent sensing.

The vision is that… the vacuum gauge allows for precise and repeatable pressure control in advanced coating technologies.

1

Stéphane Kühne – MEMS Vacuum Gauge

The aim is to develop a tool for planners of shared electric mobility to assess and optimize system design.

This leads to the design of shared electric vehicles and infrastructure that take advantage of system-wide optimization to reach higher efficiency and lower costs.

The vision is that by enabling growth and improvement through more affordable and intelligent systems, shared electric mobility will become a standard for integrated and scalable urban transportation.

1

Pratik Mukerji – Smart Dimensioning of E-Bike Sharing

The aim is to develop a software platform for the aggregation and short-term control of large groups of thermal loads (such as air conditioners, heat pumps, electric water heaters, etc.).

This leads to an enhanced controllability of the load and novel business opportunities for electricity companies by enabling the provision of control services by groups of heating and cooling devices.

The vision is that the demand side becomes more actively involved in power system control in order to increase system security and efficiency and to facilitate the grid integration of renewable energies.

1

Stephan Koch – Advanced Demand Response with Near-Term Market Potential in Electric Power Systems

Coordination

Appliance Population

setpoints

switching commands

Optimization

control services

Example: Secondary Frequency Control

The aim is to develop magnetic field sensors that enable the continuous measurement of the magnetic field evolution in MRI scanners concurrently with any MR procedure.

The field sensing technology enables advanced MR system calibration and image reconstruction approaches. This leads to faster MR scans, improved image quality and more reliable marker quantification. Eventually field sensor-based real-time feedback will reduce cost in next-generation MRI scanners

The vision is to improve patients’ lives by expanding the range and quality of diagnoses which can be made by MRI.

1

Christoph Barmet Field Monitoring for Magnetic Resonance Systems

Susanne Wolfrum & Riccardo CribiuSusanne Wolfrum & Riccardo Cribiu– Novel treatments for obesity linked type 2 diabetes

Our aim:Our aim:

• Full in vivo validation of Ba‐1• Safety profile for Ba‐1 and optimal derivatives• Develop an efficient biocatalytic synthetic route to Ba1

activeROR

RORinhibition

• Broaden IP position with novel artificial and natural Ba1 analogues

Which will lead to:• Ba‐1 as functional food/nutraceutical in/yoghurt, granola bars or fruit drinks

• Production scale synthesis of Ba‐1• Generation of artificial RORγ inhibitors• Ba‐1 derivatives/analogues as pharmaceutical 

Our vision:• Dyslipidemia Controlled nutrient

/ g pdrug candidate as part of a new venture

To develop innovative treatment options to achieve glycemic control to prevent • insulin resistance

• type 2 diabetes

• Fatty liver• Cardiovascular

complications• Insulin resistance/

Type 2 Diabetes

homeostasis

• Natural bile acid, identified by us

Ba‐1

1

yp• associated complications

• Depression• Alzheimer`s Disease

• Ba1 proved effectivein animal models

The aim is to apply our automatic video processing algorithms to webcam image streams.

This leads to a system that makes public webcams more attractive for users.

The vision is that worldwide webcams will be augmented with our technology.

1

Fabian Nater Information Mining from Webcams

!

!

!

René Jähne – Superelastic solid-state hinges

The aim is to develop SMA-based, standardized solid-state hinges as mechanical components to be integratedmechanical components to be integrated into state-of the art mechanical systems.

This leads to mechanisms which offer superior precision and high strength-to-weight ratios. Mechanisms with solid-state hinges are free from wear and do

t l ti l tiffnot release particles stiffness.

The vision is that solid-state hinges enter into market in nearly all areas ofinto market in nearly all areas of machine engineering

Cart-wheel hinge in deformedand undeformed configuration

1

The aim is to ...

develop a tool for clinicians and therapists to rapidly and objectively evaluate upper limb impairment after a stroke.

This leads to …

significant reduction of the assessment time, more objective tracking of patient’s

progress and therapy response, better selection of the therapy plan.

The vision is that … advances in technology will benefit

patients and the field of rehabilitation.

1

Marie-Christine Fluet – A Virtual Peg Insertion Test for the

Assessment of Upper Limb Sensorimotor Function in

Stroke Patients

The aim is to develop sensors that can locate and enhance incoming sounds even in noisy conditions like on a flying drone.

This leads to systems that can identify their interlocutors for a better interaction, locate people in danger, for example shooting for help in rubble or use the sound localization to navigate in complex environments.

The vision is that robots will be smarter if they can locate sound like humans do.

1

Florian Perrodin & Joël BussetMicrophone Array on a Quadrotor

F. Köhler – ELISA: Electrical detection and quantification of biomolecules

The aim is to develop a rapid detection and quantification method for acute inflammation markers.inflammation markers.

This leads to electronic devices that may be connected to smartphones, which allow

X-

doctors in hospitals or medical practices to diagnose reliably heart attacks within minutes.

The vision is that POCT centers and home users are able to test patients or themselves for relevant markers and allowLocalized

Dissolution

Electrical signal

themselves for relevant markers and allow them a first diagnosis and the decision for a possible treatment.

immobilisation

2

4

F. Felder & M. Rahim – Compact mid-infrared tunable VECSEL using MEMS micro-mirror

The aim is to realize a new type of wavelength tunable laser enabling fast and precise gas concentration measurements.

This leads to a variety of new spectroscopic applications becoming feasible once such lasers are available.

The vision is that our lasers are used in very different fields of gas monitoring, ranging from industrial quality control to medical diagnosis.

The aim is to develop an electronic handheld diagnosis device, which is capable to detect and quantify concentrations < 1-2 ng/ml of different biological molecules of interest.

This leads to the use of low-cost disposable sensing units will allow the application of one handheld device for diagnosis of multiple biomarkers within minutes.

The vision is that hospitals uses this device for low-cost diagnosis in the pre-screening of several different diseases.

3

J. Albuschies – Low-cost medical diagnosis device based on disposable silicon nanowire technology

The aim is to further enhance and prepare the fastest and most accurate barcode recognition engine today for seamless commercialization.

This leads to the automatic calibration of the recognition method to different mobile phone models, improved resilience to practical challenges like glare and shadows, and support for arbitrary barcode symbologies.

The vision is that every company offering mobile phone applications that provide services to retail products (e.g., mobile price comparison) uses the BaToo technology for product recognition.

2

R. Adelmann – BaToo: Mobile phone-based barcode scanning

6

Alexander HasseMonolithic Morphing Airfoil

The aim is to realize a fully monolithic wing based on the technology of compliantmechanisms.

This will lead to airfoils with an improved aerodynamic efficiency which canincrease the performance of airplanes, sailplanes or wind turbines.

The vision is that future airplanes, sailplanes and the blades of wind-energy turbines will use the newly developed monolithic morphing airfoil.

J. Giesbrecht – PlyEx: the ultra-high performance monolithic composite

The aim is to create a new generation of lightweight high-performance materials at lower costs than available on the market today.

This leads to lighter structures with drastically enhanced properties; exceeding those - on an equal weight basis - of steel, aluminum and glass fiber reinforced elastics, and providing full «recyclability».

The vision is that future cars use this material to be constructed much lighter, windows have a second layer of the material to become unbreakable, and the foil is used in the packaging industry to boost shelf live of products.