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An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus- eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn Regar, Patrick W. Serruys, Konstantinos Dimopoulos, Willem J. van der Giessen, Robert-Jan M. van Geuns, Giuseppe Ferrante, Simon Wandel, Stephan Windecker, Gerrit-Anne van Es, Pedro Eerdmans, Peter Jüni, and Carlo di Mario EHJ Volume 31(2):165-176 January 14, 2010 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]

An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

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Page 1: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting

stent: a LEADERS trial sub-study

by Peter Barlis, Evelyn Regar, Patrick W. Serruys, Konstantinos Dimopoulos, Willem J. van der Giessen, Robert-Jan M. van Geuns, Giuseppe Ferrante, Simon Wandel, Stephan Windecker, Gerrit-Anne van Es, Pedro Eerdmans, Peter Jüni, and Carlo di

Mario

EHJVolume 31(2):165-176

January 14, 2010

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]

Page 2: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

Trial profile. ¶Two patients allocated to sirolimus-eluting stents and clinical follow-up only (two lesions) had a clinically indicated angiography and underwent optical coherence tomography;

*One patient allocated to biolimus-eluting stents (two lesions) had one lesion excluded from the analysis for technical reasons; †Two patients allocated to sirolimus-eluting stents (four lesions)

had one lesion excluded each from the analysis for technical reasons.

Peter Barlis et al. Eur Heart J 2010;31:165-176

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]

Page 3: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

Examples of optical coherence tomography findings.

Peter Barlis et al. Eur Heart J 2010;31:165-176

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]

Page 4: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

Graphical representation of stent coverage in lesions.

Peter Barlis et al. Eur Heart J 2010;31:165-176

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]

Page 5: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study by Peter Barlis, Evelyn

Distribution of neointimal thickness.

Peter Barlis et al. Eur Heart J 2010;31:165-176

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: [email protected]