www.almacgroup.com

Almac

Overview

2

Welcome to Almac…

3

Who is Almac?

Almac is a world leading drug

development & commercial services company; providing an

expanding array of innovative

solutions worldwide across the drug development lifecycle

4

Our Vision Statement

“Almac will be the leader

in the generation of

superior solutions for the

advancement of human

health”

5

Almac: An Integrated Group

6

Milestones

7

Background

Founded in 1968

Global Headquarters in Craigavon, Northern Ireland

Turnover $0.5 billion+ (CMO market est. approx. $14bn)

~ 4,000+ Personnel Globally

Unique ownership- charitable foundation: McClay Foundation

All Profit Re-invested

8

Our Global Presence

DEPOTS ON60 6CONTINENTS

SHIPMENTS ANNUALLY

TO OVER COUNTRIES80

Facilities with 4,000+ personnel

in:

• Europe : Northern Ireland,

Republic of Ireland, Scotland,

England

• US: Pennsylvania, North

Carolina, California

• Asia: Japan, Singapore

To over 80 countries

9

Diverse Customer Base

33%

10%

10%

29%

6%

5%

4%

2%

Pharma - Large

Pharma - Medium

Pharma - Small

Biotech

CRO

Academia

Other

Speciality

Diagnostics

1%

Diverse client base across the Group assuring stability

10

Overview of Almac’s market position

Clinical

ServicesClinical

TechnologiesPharma

ServicesSciences Diagnostics

Top 3 service

provider for

clinical supply

services globally

Industry leader

– top 5 globally

Smaller player,

well known for

solid oral dose

capabilities

Smaller player,

broad range of

service offerings

supported by

excellent science

Almac Group

Smaller player,

more niche

offering

A unique range of services and solutions and a wide range of competitors

(depending on which area of the business you look at)

+ Galen (branded pharmaceuticals) and Discovery (R&D)

11

Discovery Pipeline

The Almac Group provides all of the services

required to take a new drug or compound from

concept right through to final patient delivery.

“World Class Pharmaceutical Solutions”

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

12

Services/Solutions

• Clinical Packaging

• Distribution

• Storage

• Blinding

• Commercial drug

procurement

• Supply chain

management

PHARMA

SERVICES

CLINICAL

TECHNOLOGIES

DIAGNOSTICS

& BIOMARKERS

CLINICAL

SERVICESSCIENCES

• Interactive response

technology (IRT)

• Electronic patient

reported outcomes

• Bio statistical

services

• Pharmaceutical

development

• Commercial

manufacturing

• Commercial

Packaging

• Product launch,

distribution and

other commercial

services

• API services

• Chemical

development

• Analytical services

• Solid state services

• Biocatalysis

• Peptides

• Internal diagnostic

development

• Biomarker

discovery

• Companion

diagnostics

development

13

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

14

Discovery

• A project generator for highly novel oncology programmes

for the pharmaceutical companies.

• It operates in the discovery to preclinical space and

provides Phase I ready programmes.

• Exceptionally, it may chose to take a programme into

Phase I Clinical Trials

16

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

17

Diagnostics

• Microarray based Cancer Diagnostics Company

• Develops, markets and supplies:– Leading edge genomic

expression services

– Products that will radically improve the diagnosis and treatment of cancer

18

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

19

Sciences

• API Supply

– Synthesis design

– Peptide API

• Drug Product

– Clinical manufacture

– Scale up

• Analytical Services

– Stability

– Release and comparator testing

–Method development

20

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

21

Clinical Services

• Clinical Supplies management

company

• Covers complete supply chain

for Clinical Trials:– blinding

– packaging

– global distribution

– consulting/project management

22

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

Clinical Technologies

Supported

nearly

2 millionpatients

Worked

with

18/20 top

biopharma

companies Renowned

biostats

staffConducted

trials in

60languages

Managed

2000+ clinical

studies to

date

Global

trials

conducted

across 85countries

Interactive Response Technology -

IXRS

Patient Randomization & Blind Protection

Product Inventory Management

Patient Tracking & Status

Study Management Data Availability

26

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

27

Pharma Services

Formulation Development

• - from API to tablet

Commercial Manufacture & Packaging

Distribution & Logistics

• - global distribution

• - inventory management (TROPOS)

• - 3PL & POP

• - late stage customisation

28

Discovery

Discovery R & D

Development

Process

Development

/ Scale Up

Formulation

Development

Clinical

Trials

Delivery

Manufacturing

& Packaging

Sales &

Marketing

29

Galen

• Galen promotes branded and generic prescriptionmedicines in the UK & Ireland e.g.– Calceos (for osteoporosis)

– Laxido Orange (for chronic constipation)

– Flotros (for overactive bladder)

– Penthrox (Analgesic) Launched Jan 2016

• Trustsaver Portfolio

30

Commercialisation – Galen

• Galen Ltd

• Recognised Speciality Pharmaceutical Company

• Products Sold into 23 Countries

• Successful Entrance into US Market in 2012

• Therapy Areas include:

• Oncology

• Gastroenterology

• Female Health

• Pain Management

31

The Future

• We are a global player and we will continue to

increase our presence throughout the world.

• We will continue to develop new technologies,

new medical interventions and new markets.

• We will achieve our vision.