Al l d ru g-al l erg ies must be s pec i fi ed o n m edi cat ion charts (w it h t he p ati ent ’s r eact io n) In TRUE penicillin allergy* ALL penicillins, cephalosporins and other beta-lactam antibiotic s should be avoided A ntibi o t ics t o b e av oided in penicillin allergy Am ox icillin (in Co-amoxiclav/Augmentin, Heliclear) Am pi ci ll in (in Co-fluampicil/Magnapen) Benzylpenicillin /Penicill in G Flucloxacillin (in Co-fluampicil/Magnapen) Phenoxymethylpenicillin /Penicil lin V Piperacillin (in Tazocin) Pivmecillinam Ticarcillin (in Timentin) CONTRA- INDICATED CAUTION Av oi d i f ser i ou s p eni ci ll in allergy (e.g. anaphylaxis/ angioedema) Use with c aution if non- severe allerg y (e.g. minor rash on ly) CONSIDERED SAFE A ntibi o t ics t o b e av oided o r used with caution in penicillin allergy Cephalosporins: Cefaclor , Cefadroxil , Cefalexin , Cefixime, Cefotaxime, Cefpirome, Cefpodoxime, Cefprozil, Cefradine, Ceftazidime, Ceftriaxone, Cefuroxime Other beta-lactam antibiot ics: Azt reonam , Imipenem, Meropenem, Ertapenem A nt ib i ot ic s s af e i n pen i c il li n allergy (not a complete list) Amikacin Metr on idazole Ciprofloxacin Nitrofurantoin Clarithromycin Minocycline Clindamycin Rifampicin Colistin Sodium Fusidate Co-trimoxazole Teicoplanin Doxycycline Tetracycline Erythromycin Tobramycin Gentamicin Trimethoprim Linezolid Vancomycin *TRUE penicillin allergy includes anaphylaxis, urticaria or rash i mmediately after penicillin administration In cases of INTOLERANCE to penicillin (e.g. gastrointestinal upset) or a rash occurring >72 hours after administration, penicillins/related antibiotics should not be withheld unnecessarily in severe infection but the patient must be monitored closely after administration Penicillin Allergy AUSG October 2005

Alergije Penicilin

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Al l drug-al lergies must be specified on medicat ion charts (with the patient ’s react ion)

In TRUE penicil lin allergy* ALL penicillins, cephalosporins and other beta-lactam antibioticsshould be avoided

Ant ib iotics to be avoided in

penicillin allergy Amoxicil lin (in Co-amoxiclav/Augmentin,Heliclear)

Ampici ll in (in Co-fluampic il/Magnapen)

Benzylpenicillin/Penicill in G

Flucloxacillin (in Co-fluampicil/Magnapen)

Phenoxymethylpenicillin /Penicil lin V

Piperacillin (in Tazocin)

Pivmecillinam

Ticarcillin (in Timentin)

CONTRA-INDICATED

CAUTION

Avoid i f serious penici ll inallergy (e.g. anaphylaxis/

angioedema)

Use with caution if non-severe allergy

(e.g. minor rash only)

CONSIDEREDSAFE

Ant ib iotics to be avoided orused with caution in penicillinallergy

Cephalosporins:Cefaclor , Cefadroxil, Cefalexin,Cefixime, Cefotaxime, Cefpirome,

Cefpodoxime, Cefprozil, Cefradine,Ceftazidime, Ceftriaxone, Cefuroxime

Other beta-lactam antibiot ics: Aztreonam, Imipenem, Meropenem,Ertapenem

Ant ib iot ics safe in penicil linallergy (not a complete list)

Amikacin MetronidazoleCiprofloxacin NitrofurantoinClarithromycin MinocyclineClindamycin RifampicinColistin Sodium FusidateCo-trimoxazole TeicoplaninDoxycycline TetracyclineErythromycin TobramycinGentamicin TrimethoprimLinezolid Vancomycin

*TRUE penicillin allergy includes anaphylaxis, urticaria or rash immediately after penicillin administration

In cases of INTOLERANCE to penicillin (e.g. gastrointestinal upset) or a rash occurring >72 hours afteradministration, penicillins/related antibiotics should not be withheld unnecessarily in severe infection but

the patient must be monitored closely after administration

Penicillin Allergy

AUSG October 2005