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by Jessica Drummond MPT, CCN, CHC
ALCOHOL & PERIMENOPAUSE
Do They Mix?
A Guide to the Benefits and Risks of Drinking over 40.
How Does Alcohol Impact Hormonal Health for Women over 40?
• Duringperimenopause,estrogenlevelsbecomelesspredictable
• Somewomenstrugglewithsymptomsofestrogendominance
• Estrogendominancemeanshavinghighestrogenrelativeto
progesterone,whichcanbeduetohighestrogenand/orverylow
progesterone)
• Symptomsofestrogendominanceincludebreasttenderness,
headaches,andPMSsymptomssuchaspainfulcramping
• Otherwomenstrugglewithlowestrogen,whichcanleadtolow
libido,vaginaldryness,andjointstiffness
• Aromataseisanenzyme(achemicalinthebody)thatconverts
testosteronetoestrogen
• Alcoholimpactsaromatase
integrativewomenshealthinstitute.com
How Does Alcohol Impact Hormonal Health for Women over 40?
• Redwinedecreasesaromataseconversioninyourbody(keepingestrogen
levelslower,butsupportinghighertestosteronelevels-assumingsome
otherfactors)
• One5oz.glassofredwinedailymaybeprotectiveagainstbreastcancer
• Redwinealsocontainstheantioxidantresveratrol,whichcanbeprotective
againstheartdisease.But,notinhighenoughdosesinwinetohavea
significanteffect
Thus, when deciding what kind of alcohol to drink, keep in mind...
• Drinkingmostalcohol(eveninsmalldoses)mayincreasebreastcancerrisk
• Theexceptionisredwine,whichinmoderateamountsmaybeprotective
• Drinkingalcoholmaybebeneficialforcardiovascularhealth
• Ifyouhavelowestrogen,drinkingmoderateamountsofwhitewinemay
helpyourlibidoandvaginaldryness
integrativewomenshealthinstitute.com
integrativewomenshealthinstitute.com
Alcohol Impacts Hormone Balance, Cancer and Heart Disease Risk
• Whitewineandmostotheralcoholicbeveragesincrease
aromataseconversioninyourbody(increasingestrogenlevels)
• One5oz.glassofwhitewineor1.5ozofalcoholicspirits(suchastequila,vodka,orgin)dailymaybeprotectiveagainstcardiovasculardisease,especiallyifyourestrogenlevelsarelow
• Drinkingmoderateamountsofalcoholdaily(1drinkperday)forwomencanbeprotectiveagainstcardiovasculardisease
• But,eventhissmallamountofalcoholdailycanincreasebreastcancerrisk
Liver Detoxification Pathways & Supportive Nutrients
integrativewomenshealthinstitute.com
Endotoxins*endproductsofmetabolism*bacterialendotoxins
Exotoxins*drugs(prescription,OTCs,recreational,etc.)*chemicals-agricultural-foodadditives-household-pollutants/contaminants*microbial
INTERMEDIARYMETABOLITES
(more polar, more water-soluble)
PHASE 1(cytochrome P450 enzymes)
PHASE 2 conjugation pathways
TOXINS(non polar,
lipid-soluble)
TOXINS(non polar,
lipid-soluble)
Serum
Kidneys
UrineBile
Faeces/stool
ReactionsCofactors & other
Nutrients Used
lipid-soluble(nonpolar)toxinsstoredinadipose(fat)tissuecontributetoincreased/mobilizedtoxinloadwithweightloss
oxidationreductionhydrolysishydrationdehalogenation
riboflavin(vit.B2)niacin(vit.B3)pyridoxene(vit.B6)folicacidvitaminB12glutathionebranched-chain
aminoacidsflavonoidsphospholipids
Free Radicals
Superoxide
Reactive Oxygen Intermediates
Antioxidant/ProtectiveNutrients/Plant
Derivatives
carotenes(vit.A)ascorbicacid(vit.C)tocopherol(vit.E)seleniumcopperzincmanganesecoenzymeQ10thiols(foundingarlic,onions,&
cruciferousvegetables)bioflavonoidssilymarinpycnogenol
Reactions:sulfationglucuronidationglutathioneconjugationacetylationaminoacidconjugationmethylation
Nutrients Used:glycinetaurineglutamine*NAC
*N-acetylcysteine, cysteine, methionine are precursors
SecondaryTissue Damage
integrativewomenshealthinstitute.com
Here is how things work...
Alcohol toxins enter the liver
Phase one: detoxification occurs
(Glutathione, vitamins, and micronutrients
are necessary for this process)
Intermediate stage
(Need adequate antioxidants to protect the liver)
Phase two: need amino acids
Excrete molecules
(kidneys > bladder > urine and colon > rectum > stool)
Alcohol and Liver Health
Alcoholistoxictotheliver,
whichcanhaveanimpact
onyourhormonebalance
sinceestrogenmustalsobe
metabolizedbytheliver.
Ifyou’restrugglingwith
constipationordehydration,
youwillhavedifficulty
eliminatingthetoxic
byproductsofalcohol.
How Can I Support My Liver?
integrativewomenshealthinstitute.com
Eat8-10servingsofvegetables
perdaysoyouhaveadequate
antioxidantstohelpwiththe
intermediatephase.
Takeglutathione(availablehere)
supplementsondaysyouknowyou
willbedrinking.Thiswillhelpwith
phasedetoxification.
integrativewomenshealthinstitute.com
Next steps...
Ifyou’restrugglingwithsymptomsofhormonalimbalance,suchas:
• Weightgain(ordifficultylosingweight)
• Hairloss
• Fatigue
• Insomnia
• Lowsexdrive
• Vaginaldryness
• Anxiety
• Hotflashes
• Nightsweats
Learnmoreaboutoursimple,
3-stepApproachtoHormoneBalance.CLICK HERE >>