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1/19

Acute Kidney Injury

Haidar Alatas

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2/19

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Gambaran Klinis GGA

HB normal

Oliguric type

Non oliguric type (30-0!" #prognosis lebi$ bai% # causa AB &nep$roto'ic agent

mumnya re)ersible

*ortalitas tinggi+ ,0-0!

re%uensi + .-/.! pasien raat

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4/19

1enyebab GGA

1re-renal + Hypo)olemic2 $ypotensi2de$ydrasi2 syo%

enal (Intrinsic renal 4ailure" # A5N(acute tubular nep$rosis" or 6*N()ascular membrane nep$rosis"

1ost-renal + obstru%si2 batu2 prostat2trauma2 %eganasan7

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5/19

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Anamnesis

Gastro 8nteritis a%ut

iayat tinda%an & operasi

Hipotensi

s$oc% Hipertensi (accelerated & malignant"

9rugs

enal disease

Acute on c$ronic

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7/19

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Gambaran %lini% A

Onset 1$ase + oliguria2 ureumcreatinin mening%at2 gangguanele%trolit

Oliguric 1$ase + :uid o)erload2edema an%le&pulmo2 $yper%alemia cardiac2 aryt$mia2 $yponatremia2acidosis2 %ussmaul respiration7

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Gambaran %lini% A

9iuretic 1$ase + restorasi 4ungsiginjal

/ $ari s&d ; minggu Keseimbangan cairan2 de$ydrasi2

$ypo%alemia

Gejala-gejala $ilang2 na4su ma%an puli$

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10/19

Acute uremic syndrome

7/26/2019 Aki s1 Perawat

11/19

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12/19

1enya%it apa saja penyebaba%i

(/"7 1enya%it yang menyebab%an $ipoper4usipada ginjal tanpa %erusa%an integritas dariparen%im ginjal (GGA prerenal2 prerenal

a?otemia" (@..!"7(;" 1enya%it yang secara langsungmelibat%an paren%im renal (GGA renal2 renala?otemia" (@,0!"7

(3" 1enya%it yang ber$ubungan dengansumbatan pada saluran %emi$ (GGApostrenal2 postrenal a?otemia" (@.!"7

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1rerenal ailure

Ad)anced $eart disease it$ )ery lo cardiac output

=ystemic sepsis7

8'tracellular )olume depletion7

Acute blood loss 4olloing2 4or e'ample2 major trauma

or gastrointestinal or postpartum $emorr$age7

5$ird space :uid loss in patients it$ intestinalobstruction or ileus

=e)ere burns

Hepatic 4ailure may cause $epatorenal syndrome7 *edications2 including angiotensin-con)erting en?yme

(A

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enal ailure

Administration o4 nep$roto'ic drugs+aminoglycoside7

Administration o4 radiograp$iccontrast media7

Acute glomerulonep$ritis7

1re)ious renal transplant it$ acuteor c$ronic rejection7

=ystemic sepsis

https://www.clinicalkey.com/%23!/ContentPlayerCtrl/doPlayContent/21-s2.0-1014813https://www.clinicalkey.com/%23!/ContentPlayerCtrl/doPlayContent/21-s2.0-1014813https://www.clinicalkey.com/%23!/ContentPlayerCtrl/doPlayContent/21-s2.0-1014813https://www.clinicalkey.com/%23!/ContentPlayerCtrl/doPlayContent/21-s2.0-1014813

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1ostrenal ailure

enal calculi7

Benign prostatic $yperplasia7

1rostate cancer7

Bladder cancer7

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16/19

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17/19

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18/19

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TERIMAKAS

IH