Agilent ChemStation What’s New ? Revision B.04.02 ...€¢ No support for 1290 LC, 7100 CE Diagnostics Diagnostics in Lab AdvisorDiagnostics in Lab Advisor • 1100/1200 modules:1100/1200

Agilent ChemStation What’s New ?gRevision B.04.02 Adopting new technology

© Agilent Technologies 2010

Agilent ChemStation – Modern Instrument Control

Agilent RC.NET driver technology

• New Method & Run Control view

• XML method format

• Method migration

• LC/CE Method resolution• LC/CE Method resolution

• LC Macro compatibility

• GC News

Agilent ChemStation B.04.02© Agilent Technologies 2010

ChemStation B.04.02 – New Look for LC & CENew Look Classic LookNew Look Classic Look

Drivers RC.NET driver architecture ChemStation driver architecture

Instrument User Interface

Common UI (& drivers) inEZChrom and ChemStation

Proprietary UI – ChemStation only

SupportedModules

• 1100/1200 standard modules• 1290 modules, 7100 CE

• All 1100/1200 modules• No support for 1290 LC, 7100 CE

Diagnostics Diagnostics in Lab Advisor • 1100/1200 modules: Lab AdvisorDiagnostics Diagnostics in Lab Advisor • 1100/1200 modules: Lab Advisor• 1100 modules: Diagnostics View

OQ/PV • Limited OQ/PV View• Instrument qualification in ACE

• OQ/PV View available• Instrument qualification in ACE

Agilent ChemStation B.04.02

• Instrument qualification in ACE • Instrument qualification in ACE


The New Look of the LC ChemStation in DetailStart/Stop/Pause buttons

Method information area

Instrument dashboard area for all modules

UI access to data analysis and ECM preferencespreferences

Information area or current samplep

Access to sample tray


The New Look of the CE ChemStation in Detail

Instrument dashboard area for all modulesfor all modules

The new G7100A CE instrument is only supported with RC NETwith RC.NET drivers.


The New Instrument Method Editor Single Method UI with one tab per modulemodule

Hide/show common timetable graph for all modules


Changes & Benefits of RC.NETNew Interactive Method & Run Control View*

• Modern Navigation Elements and Design

– Tooltips context menus one-click access to dialogs etcTooltips, context menus, one click access to dialogs etc.

• Dashboard for Instrument Control replaces System Diagram

– Customizable

– Intuitive graphics, icons reveal additional information

– Display capabilities for multiple modules of the same type (e.g. pumps)

– Focus on most important information, visible even from a distance

Show/hide more detailed information per module– Show/hide more detailed information per module


* Not yet in GC ChemStation


Instrument Dashboard Capabilities – Demo

Customizable representation– Continuously adjustable in size– Show/hide elements

Freel arrange order of displa ed mod les

User Interface Demo Video

View video in explorer

– Freely arrange order of displayed modules – Choice to display more details per module– View modules of interest, minimize others

New intuitive instrument graphics

Dashboard Demo Video

New, intuitive instrument graphics – Easily identify the module – See current status– Access method settings

Most important information at a glance– See current values, method settings & limits – Clearly see status, even from a distance

Enhanced capabilities– Display multiple modules of the same type

(for example, pumps).


http://www.chem.agilent.com/en-US/Products/software/datasystems/chemstation/PublishingImages/CSD_customizeMRC.swf

http://www.chem.agilent.com/en-US/Products/software/datasystems/chemstation/PublishingImages/CSD_customModule.swf

Instrument Dashboard Capabilities – Demo

Customizable module names– Individual device names help to better distinguish identical

modules. (user’s choice)

Icons reveal more information– external contact board installed (see picture)– RFID tag present for

lView video in explorer

• columns• flow cell, or • lamp

– Tool tips reveal information stored in tags

Dashboard Icons

Demo Video

Instrument method editor– Single tabbed method user interface.

Method EditorDemo Video


Embedded in new Method & Run Control View– Run control– Sample information area

Run Control Demo VideoVi id i l


Sample information area



http://www.chem.agilent.com/en-US/Products/software/datasystems/chemstation/PublishingImages/CSD_icons.swf

http://www.chem.agilent.com/en-US/Products/software/datasystems/chemstation/PublishingImages/CSD_instrumentmethod.swf

http://www.chem.agilent.com/en-US/Products/software/datasystems/chemstation/PublishingImages/CSD_NewMRC.swf

Changes & Benefits of RC.NETNew Interactive Method & Run Control View*New Interactive Method & Run Control View

• Not Ready status color

– Changed from red (now only used for error state) to yellowyellowChanged from red (now only used for error state) to yellowyellow

• Sequence and method change flags

– Sequence change flag moved to new sequence areaq g g q

– Method change flag moved to new method area

• LC Instrument Diagnostics

– No longer part of ChemStation

– Now entirely done in Lab Advisor

– Single, data system-independent application for diagnostics


* Not yet in GC ChemStation


Changes & Benefits of RC.NETGC ChemStation News

• 7693A ALS support on 6890 and 6850 GC systems

– New 7693A Automatic Liquid Sampler system can now be controlled withNew 7693A Automatic Liquid Sampler system can now be controlled with 6890 & 6850 Gas Chromatographs


Changes & Benefits of RC.NETMethod handlingg

• New instrument method format– XML file structure

– Same format for ChemStation & EZChrom

– Checksum-protected

• Method migration– done automatically (no extra step)

– converted during method load (change flag is set)

– Silent migration during automation

Method resol tion (online ChemStation)• Method resolution (online ChemStation)– Consistency Check: Does method match current configuration?


Method Resolution in Detail – What happens?New LC or CE RC.NET drivers

Method Resolution Type ConsequenceMethod Resolution Type Consequence

Consistent Method can be used –no modification required

Automatically Resolvable Method can be used –internal schema migration

Manual Resolution Recommended Method can be used –Optional parts of the method are removed

Manual Resolution Required

Method must be modified


Method Resolution in Detail – ExamplesNew LC or CE RC.NET drivers

Method Resolution Type ExampleMethod Resolution Type Example

Consistent Method has new format and fits current configuration

Automatically Resolvable Old method is migrated (*.reg or *.mth *.XML format)

Manual Resolution Recommended Removed unused settings, e.g. external contacts board is not installed but part of method


Configuration mismatch, e.g. quaternary vs. binary pump


Method Resolution in Detail – AutomationNew LC or CE RC.NET drivers

Method Resolution Type AutomationMethod Resolution Type Automation

Consistent Method is loaded and executed

Automatically Resolvable Method is loaded and executed

Manual Resolution Recommended Method is loaded, changed and executed; logbook entry describes change


Method is skipped; logbook entry describes reason


Macro CompatibilityImpact of the RC.NET driver introduction p

• Data analysis or reporting macros– not affected, no changesnot affected, no changes

• Macros that interact with instruments– may require modification

• Register interface still exists– Same capabilities as before

– provides access to items, such as

• method parameters

• status informationstatus information


Macro Compatibility DetailsMajor Differences compared to classic driversj p

• Register names are different

• Module status register content split into two:Module status register content split into two:

– status register

– configuration register

• Header item and table names inside register are mostly different

– Some header items have been split into two parts, for example StopTime no split intoStopTime now split into:

• StopTime_Time

• StopTime_Mode (either SET or NOLIMIT)p _ ( )

• New Pretreatment register hosts Injector program– no longer part of the method register


LC/CE ChemStation B.04.02 Device Support

Device Type RC.NET UI Classic UI

1100 / 1200 standard & RR modules1100 / 1200 standard & RR modules (incl. SQ MSD & 35900E A/D)

1290 LC modules, 7100 CE

1290 with standard 1100/1200 modules

“Special” modules*Special modules

SQ MSD with 1290 or 7100

35900E A/D with 1290 or 7100

* RC.NET drivers will be available in the near future ! Special Modules are: Preparative system (G1361A, G1391A, G2260A), Micro / Nano system (G1382A, G1377A, G1387A,


G2225A), Fraction Collector (G1364A), Dual Loop Autosampler (G2255A), ChipCube (G4220A), Cluster Drivers (G1316C TCC Cluster, G1160A/Pump Cluster)


Agilent ChemStation – General Changes

General Changes

• Sequencing

• Instrument Qualification

• Diagnostics

• New version of OpenLAB• New version of OpenLAB Intelligence Reporter


General Changes in ChemStation Sequencingq g

• Easy Sequence

– New user interface for simple sequence planning and queuingNew user interface for simple sequence planning and queuing

• New Sequence printout

– Format was changed to allow printing of very long names and text fieldsg p g y g


Easy Sequence In more detail…

Easy Sequence consists of two phases

• Planning• Planning– Easy Sequence Template – Samples

– Easy Sequence Template – Calibration

• Execution– Easy Sequence – Submission

– Sequence Queue – Scheduled SequencesSequence Queue Scheduled Sequences


Easy Sequence Template – SamplesPlanningg

Define sequence qcharacteristics –

• Method

• Namingg

• Data location


Manager


Easy Sequence Template – CalibrationPlanningg

Define sequence qcharacteristics –

• Calibration type

• Blanks

• Control samples

• Methods


Manager


Easy Sequence – SubmissionExecution

Create sequence qbased on template –

• Modify available parameters as neededneeded

• Review

• Submit to queue


Operator


Sequence Queue – Scheduled SequencesExecution

Monitor queue –q

•Active queue

– Pause / Resume

– Change order

•History queue


Operator


Easy Sequence What are the key benefits?y

It…

• … is easier to use

• … less error-prone due to pre-configured templates

t di ti t l l f l i d ti• … two distinct user levels for planning and execution

• … provides sequence queuing capabilities


Instrument QualificationAgilent Compliance Engineg p g

• All Agilent instrument qualification is delivered with ACE

– Single application for deliverySingle application for delivery

– independent of data system

• ChemStation OQ/PV View

– Not used for Agilent delivery of qualification services

– Still fully available with classic drivers

– Will entirely disappear in near future


Instrument Diagnostics Lab Advisor

• Agilent instrument diagnostics done with Lab Advisor

– Single application for diagnosticsSingle application for diagnostics

– independent of data system

• ChemStation Diagnostics Viewg

– Latest Agilent hardware not included

– Still available with classic drivers

– Will entirely disappear in near future


General Changes in ChemStation Reportingp g

• NEW with OpenLAB Intelligence Reporter revision A.02.01*

– Easy to use Report Template Editor (RTE)Easy to use Report Template Editor (RTE)

– Reporting of chromatograms for one or multiple injections

– Reporting of calibration curves

– Reporting of spectra

– New “Quick Query” function

– OLIR Client without direct database connection

– New report controls for MS BI Studio


*separate application, requires OpenLAB Enterprise Content Manager


OpenLAB Intelligence Reporter Advanced ChemStation Reportingp g

ECM-based advanced report builder integrated into ChemStation for:g

– Sequence summary and cross-sequence reporting

– Custom calculations, trend-charting

– Decision-based results reporting


OpenLAB Intelligence ReporterMore details…

• Extended reporting and knowledge generation via

– search-based report content selectionsearch based report content selection

– condense information by visualizing key results (e.g. in trend charts)

– decision-based result presentation(flag outliers, automatically sort results by pass/fail criteria, etc.)

– custom calculation(e.g. summary calculations, statistics, complex reports like Dissolution Tests)

• Report on data from Agilent data systems stored in OpenLAB ECM

• Capabilities to report on non-chromatographic data(ECM administration, ECM usage, ….)


What’s New in ChemStation Revision B.04.02Summaryy

• New Method & Run Control View – Modern design with intuitive navigation elements is complemented by the new dashboard for easy g y yinstrument control.

• Full compatibility of existing methods is facilitated by automatic method i ti d th th d l timigration and the new method resolution.

• Easy sequence is a new user interface for simple sequence planning, submission and queuingsubmission and queuing

• Agilent Compliance Engine for instrument qualification of the entire lab

• Lab Advisor – one application for instrument diagnostics independent of the data system

• Advanced Reporting capabilities with OpenLAB Intelligence Reporter i i B 02 01


revision B.02.01


Documents

Agilent ChemStation What’s New ? Revision B.04.02 ...€¢ No support for 1290 LC, 7100 CE Diagnostics Diagnostics in Lab AdvisorDiagnostics in Lab Advisor • 1100/1200 modules:1100/1200