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Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

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Page 1: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Administering Hyaluronic Acid to Performance

Horses

Karey L. McPheeDecember 4, 2008

ANSC 590

Page 2: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Performance Horses Racing, endurance, cutting,

rodeo, etc… Susceptible to joint issues like

any athlete Weight vs. Joint Size

Success administering H.A. for joint problems

Essential for joint health Bodies produce less H.A. after

4 years old (Engstrom-Laurent, 1989) OCD, DJD, Epiphisitis,

Arthritis

Page 3: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Healthy Joints

Page 4: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Hyaluronic Acid Ubiquitous in

vertebrates Naturally occurring

Sodium Hyaluronate Combined with blood

plasma synovial fluid (Nizolek and White, 1981)

Lubricates joints Highly viscous

Provides nutrients to cartilage and surrounding tissues

Page 5: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Three Common Administration Methods

Direct Injection

Intravenous Injection

Oral Administration

Page 6: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Direct Injection Draw out existing fluid and inject:

HA Legend (Bayer)

Cortisone Polysulfated Glycosaminoglycans

(PSGAGs) Adequan (Luitpold)

Invasive Downtime Expensive Destructive? (Treiber, 2007) Masks problem

Pierce, 2003 suggests HA goes elsewhere

Page 7: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Intravenous Injection Maintenance practice Distributed via blood

Circulating H.A. lasts 2-3 days (Pierce, 2003)

Painful Invasive Expensive

IV Legend $25/shot Not as effective as oral

H.A. to increase H.A. serum levels (Pierce, 2003)

Page 8: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Oral Administration Several Forms

Powder Easiest to administer

Gel Cost effective

Nutraceutical/mineral package

1-3 days as needed Non-invasive More effective method for

maintaining H.A. serum levels (Pierce, 2003)

Page 9: Administering Hyaluronic Acid to Performance Horses Karey L. McPhee December 4, 2008 ANSC 590

Prevention!!!!! More cost effective to prevent

joint issues rather than treat Best way to prevent

Oral H.A. Consistent

Increase performance Horses “protect” themselves

Pain decreases performance Maximize days in training

Less days out due to soreness

On average 5 more days in training (Pierce, 2003)

Extend competitive career Sound horses last longer!