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Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to the right of the human ideogram in Mb. The chromosome numbers of the orthologous segments in the analyzed species are indicated to the right of the conserved segments. Chromosomal breakpoints have been evenly spaced in order to facilitate visualization of the conserved syntenic segments. The resulting ideograms of the chromosomes and conserved segments are therefore not drawn to scale. The centromeric region is indicated by a black horizontal bar. The stippled red lines indicate breaks present in all analyzed vertebrate genomes which may therefore be attributed to rearrangements in the primate lineage.

Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

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25.47 – – – – – – – – – – – – – – – – – – Un – – – – – – – – – – – – – – – – – – – – – – – – – – – – human rat mouse dog cow chicken HSA 2 opossum

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Page 1: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

Additional file 1:

Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to the right of the human ideogram in Mb.

The chromosome numbers of the orthologous segments in the analyzed species are indicated to the right of the conserved segments. Chromosomal breakpoints have been evenly spaced in order to facilitate visualization of the conserved syntenic segments. The resulting ideograms of the chromosomes and conserved segments are therefore not drawn to scale. The centromeric region is indicated by a black horizontal bar. The stippled red lines indicate breaks present in all analyzed vertebrate genomes which may therefore be attributed to rearrangements in the primate lineage.

Page 2: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

human

rat mouse

dogco

wch

icken

10.38 – 10.39

5

16.05 – 16.08

16

22.99 – 23.09

21

33.63 – 33.652

2

41.84 – 42.2923

43.09 – 43.30

311 21

53.00 – 53.00

153

53.64 – 53.6812

67.23 – 67.34

5 4

67.61 – 67.88

5

68.01 – 68.284 6

89.56 – 89.562 3

93.54 – 93.63514

109.30 – 110.24

8

111.70 – 111.70

6

115.59 – 115.9026

119.83 – 119.971

121.10 – 141.30142.78 – 142.90

8

143.08 – 143.2210

146.67 – 146.691

149.94 – 150.14

17

154.62 – 154.787

155.14 – 155.18

2 3

158.43 – 158.47

25

163.57 – 163.61

388

166.29 – 166.291164.90 – 165.24

3

183.69 – 186.80

7

193.45 – 193.5238

197.56 – 197.67

8

199.88 – 199.8832

199.89 – 200.00

7

203.17 – 203.2038

206.37 – 206.39

26

211.80 – 212.137

219.91 – 220.2138

222.90 – 223.12

3

223.81 – 224.23

13 1

7

16

14

224.99 – 225.1810 11 14 7 2

228.01 – 228.8428

229.83 – 230.8211

231.62 – 231.62

19 8

236.40 – 236.5817 13

428

243.42 – 243.7913 1 7 16

244.10 – 244.1610 11 8

245.541 7 14

7

3

un

HSA 1

opossum

01.85 – 02.2801.27 – 01.30

42

4

2

6

2

Page 3: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

25.47 – 26.3212

28.94 – 28.955

38.21 – 38.43

3

40.57 – 42.1942.90 – 42.90

17

43.73 – 43.78

1114

44.13 – 44.3115

50.49 – 53.81

617

68.54 – 68.6114 11

68.79 – 68.91

3

71.13 – 71.21

10

22

73.82 – 73.974

75.34 – 75.63

22

76.58 – 76.5834

91.60 – 94.70

64

95.21 – 95.2414

96.46 – 96.623 2

17

97.81 – 97.83

Un

106.27 – 106.88

1

108.46 – 108.52

9

17 1

110.02 – 110.2020 10

10

112.81 – 112.963

113.72 – 114.193 2 17

11

14

125.39 – 127.1313 1

127.82 – 127.957

128.50 – 128.5718 18

132.07 – 133.009

9

138.27 – 138.5613

1

188.24 – 188.983 2153.44 – 154.55

19

189.70 – 190.1336

220.33 – 222.11

7

224.73 – 225.07

37

233.47 – 233.47

2

234.16 – 234.17

9

238.73 – 238.757

238.98 – 239.109

240.68 – 240.807

243.6

9 1

253

9

96.64 – 96.68

1

74.82 – 74.9774.35 – 74.53

5

1

7

1

131.94 – 131.96

4

3

201.28 – 201.51

4

230.76 – 231.40

7

2

238.89 – 238.937

241.29 – 241.37

2

7

human

rat mouse

dogco

wch

icken

HSA 2

opossum

Page 4: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

10.30 – 10.3022

10.47 – 11.289

12.18 – 12.7522

12.86 – 13.00

4 6 20

15.12 – 15.22

822

12

16.32 – 16.3316 14

20.20 – 21.449 17

1

26.73 – 27.1327

27.47 – 27.7315 14

44.47 – 44.73

23

45.16 – 45.41

2

44.87 – 44.88

48.24 – 48.42

22

9

52.30 – 52.33

8 9

57.89 – 57.9716

63.98 – 64.0515

14

74.62 – 77.174 6

2022

12

88.27 – 88.2831

90.60 – 95.00

102.71 – 102.76

1

103.60 – 103.6411

122.75 – 122.977

1123.14 – 123.19123.72 – 123.73

1

127.18 – 127.21

11 1633

7

1

127.86 – 128.777

130.52 – 130.5822

131.18 – 131.64

4 6 208

12

134.86 – 135.012

139.50 – 139.559

139.83 – 139.867

148.62 – 149.90

8 9

150.90 – 150.94

1

151.17 – 151.6121

159.93 – 160.00

23

184.30 – 184.32

2 3

194.76 – 195.60

34

199.33

11 16

33

1

9

6

33.16 – 33.40

8

39.21 – 39.286

42.28 – 42.518

42.89 – 42.926

46.23 – 46.45

8

6

99.80 – 99.93

7

4

6

8

142.50 – 142.68

4

184.47 – 184.69187.79 – 187.81

7

274

human

rat mouse

dogco

wch

icken

HSA 3

opossum

Page 5: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

192.00

00.99 – 00.99Z

41.11 – 41.203

49.40 – 52.5074.30 – 74.64

6

74.85 – 74.9728

75.69 – 76.76

13

89.43 – 89.43

14 5

95.62 – 95.734 6

100.37 – 100.37

32

100.71 – 100.7912

106.75 – 106.94

6

107.25 – 107.3229

120.91 – 121.34

2 332

122.66 – 122.666

123.15 – 123.45

4 6

141.00 – 141.622 3

144.75 – 144.79

19

149.72 – 151.3619 8

163.44 – 164.412 3

167.38 – 169.38

17

169.74 – 169.79

15

176.27 – 176.9325

816 8

16 27

45

human

rat mouse

dogco

wch

icken

HSA 4

opossum

Page 6: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

01.69 – 01.851

07.96 – 09.1017

13

14.75 – 15.67

34

31.59 – 31.68

2

32.82 – 33.48

20

35.27 – 35.6519

42.85 – 43.56

15

45.80 – 49.6054.37 – 54.43

4

74.20 – 74.362

20

76.30 – 76.36

Z

78.46 – 78.6113

79.53 – 79.74

10

96.28 – 96.30

2

13

98.29 – 99.901 17

102.64 – 102.911

102.93 – 106.74

Z

110.03 – 110.1017

7

112.29 – 112.88

3

112.96 – 113.73

10

114.99 – 115.45

10

127.90 – 128.33

Z

129.55 – 130.53

18 18

10

134.09 – 134.1010 11

137.12 – 137.1717 13

138.69 – 138.71

11

147.57 – 147.672

7

148.01 – 148.1918 18

150.26 – 150.38

19

167.89 – 167.927

171.81 – 172.1311

172.13 – 172.1920

172.59 – 172.6717

173.47 – 174.08

10

113

175.71 – 175.7310

176.91 – 176.95

4

176.97 – 177.3517 13

180.01 – 180.55

13

180.8310 11

117

16

110.49 – 111.09

9

111.12 – 111.51

3

6

114.91 – 114.943

122.78 – 124.006

130.76 – 130.79

3

1

2

human

rat mouse

dogco

wch

icken

HSA 5

opossum

Page 7: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

25.81 – 28.98Histone Cluster

2

29.16 – 29.18

17 1335

29.76 – 29.8030.02 – 30.14

12

30.29 – 30.4035

33.49 – 33.65

16

35.55 – 35.5526

36.31 – 36.3732

37.25 – 37.4326

39.16 – 39.18

20 17

39.40 – 39.4115 14

40.66 – 41.12

3

42.27 – 42.2826

49.81 – 49.91

17

52.74 – 52.76

9

1

55.85 – 56.438 9

58.70 – 61.9063.05 – 63.40

23

74.03 – 74.19

9 1

86.41 – 87.858 9

100.17 – 100.945 4

108.06 – 108.47

9

109.11 – 109.5211

116.68 – 116.71

12

123.17 – 123.36

20

131.65 – 131.94132.11 – 132.17

1

12

154.92 – 155.15

10

169.91 – 169.921

170.08

1

1712

9

3

3

2

human

rat mouse

dogco

wch

icken

HSA 6

opossum

Page 8: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

06.64 – 07.0512 5 6 25 14

12.23 – 12.384 6

22.01 – 22.546 12

23.01 – 23.065

32.88 – 32.916

36.27 – 36.338 9

37.55 – 37.66

14

43.62 – 43.6817 13

47.76 – 47.80

18

16

55.05 – 55.21

14 11

55.53 – 55.644 6

18

4 2

57.80 – 61.7075.90 – 76.40

12

5

6 25 19

84.40 – 85.9218

86.49 – 86.621

92.11 – 92.4097.15 – 97.26

4

614

42

99.11 – 99.1214

99.92 – 99.92un

100.48 – 100.559

101.85 – 101.98

125

6 25

19

104.80 – 104.844

107.76 – 107.8018

111.71 – 112.006 12

120.09 – 120.22

4

120.63 – 121.1129

122.43 – 122.694

123.20 – 123.9824

126.63 – 126.81

1

128.40 – 128.42un

129.74 – 130.4714

133.72 – 133.79

14

143.54 – 143.591

150.00 – 150.08

6

156.71 – 156.835

158.50

4

6 12

16

4

2

4

6

30.32 – 30.41

8

6

44.70 – 44.801

6

2

8

6

2

8

human

rat mouse

dogco

wch

icken

HSA 7

opossum

Page 9: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.48 – 00.6025

01.72 – 01.7637

05.76 – 06.28

un

07.87 – 08.21

3

09.68 – 09.95

16 816

274

11.76 – 12.0315 14 25 3

14.46 – 15.44

83

19.75 – 19.8427

20.16 – 21.59

816

26.78 – 27.1522

27.22 – 27.24

8

27.53 – 27.535

29.18 – 29.25

15 14

16

25

83

31.15 – 31.62

4

4

33.45 – 33.46Z

42.38 – 42.67un

43.06 – 43.08Z

43.50 – 47.50

16 8 16 27

4

50.00 – 51.4711 16

56.60 – 56.811

64.16 – 65.665

4

67.25 – 67.502 3

76.11 – 76.485 1

87.31 – 87.312 3

97.24 – 97.315 4

98.81 – 98.86

29

124.62 – 124.73

14

125.57 – 125.6217

146.20

7 1513

14

2

06.66 – 07.09

1

351

17.99 – 18.115

1

5

1

3

human

rat mouse

dogco

wch

icken

HSA 8

opossum

Page 10: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

05.82 – 05.881

06.50 – 06.751 19

32.78 – 32.96

8

33.16 – 33.245

38.41 – 39.05

5 411

846.00 – 64.00

17 13

76.55 – 77.0277.88 – 78.08

16

79.57 – 81.77

1 19

5

91.79 – 92.05

Z

94.17 – 94.4012

96.88 – 97.08

17 13

1

98.10 – 98.13Z

100.43 – 100.872

108.78 – 108.78Z

109.31 – 109.622

112.73 – 112.99Z

120.56 – 120.61

4

121.21 – 121.54

11

8

138.3023

9 1117

89.34 – 89.45

6

3

6

1

human

rat mouse

dogco

wch

icken

HSA 9

opossum

Page 11: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

03.82 – 04.862

05.90 – 05.9413

06.06 – 06.0914

15.05 – 15.131

27.57 – 27.83

2

32.68 – 32.78

17

18

35.14 – 35.3419 8

35.97 – 37.4517 18

2 13

2

39.20 – 41.804

45.61 – 45.644 6

28

48.06 – 48.364

51.56 – 51.6216 14

28

28

6

54.20 – 55.251 19

57.79 – 59.6326

26

59.80 – 59.8274.53 – 74.54

20 10

79.30 – 79.4115

88.94 – 89.2516

144

28

91.09 – 91.1626

120.93 – 121.2519

135.80

17

2826

8

1

human

rat mouse

dogco

wch

icken

HSA 10

opossum

Page 12: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

01.01 – 01.2029

5

03.20 – 03.62

18

07.05 – 07.231

18.08 – 18.2115

25.06 – 26.31

1 7

295

51.40 – 54.7057.34 – 57.63

3 2

18

30.21 – 30.30

21

33.65 – 33.683

59.24 – 59.28

18

59.92 – 60.02

15

60.24 – 60.2821

65.15 – 65.1565.59 – 65.59

un

5

65.90 – 65.923

66.50 – 66.53un

68.46 – 68.50

19

70.94 – 71.32

18

5

75.60 – 76.05

29

15

76.41 – 76.4213

76.68 – 76.9815

89.07 – 89.51

1

7

93.55 – 93.9229

100.96 – 101.4215

101.61 – 101.772

110.09 – 110.84

1

123.12 – 123.1315

133.53 – 133.5329

134.615

58 9

24

100.51 – 100.89

21

00.82 – 00.8329

5

4

63.50 – 64.38

5

67.02 – 68.21

8

5

4

human

rat mouse

dogco

wch

icken

HSA 11

opossum

Page 13: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

07.55 – 07.5551

08.58 – 08.6509.36 – 09.64

1

10.22 – 10.2616

32.42 – 32.55

4 6

32.94 – 33.4211 16

34.30 – 36.7046.39 – 46.65

1

53.27 – 53.63

15

53.93 – 54.32

27

56.26 – 56.62

7

74.19 – 74.1910

98.88 – 98.93

5

100.02 – 100.023

103.03 – 103.18

15

103.89 – 103.935

105.04 – 105.132

106.67 – 107.035

7

10

101

132.0012 5 26 17 15

8

3

human

rat mouse

dogco

wch

icken

HSA 12

opossum

Page 14: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

25.52 – 25.6000.00 – 17.80

15 14

33.31 – 34.4112 5

40.14 – 40.403

25

51.23 – 51:3315

2

14

51.48 – 51.84

22

52.06 – 52.1216 8

25

9 1101.85 – 102.05102.35 – 102.49

1415

114.5016 8

22

12 1

4

45.58 – 45.607

4

7

human

rat mouse

dogco

wch

icken

HSA 13

opossum

Page 15: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.00 – 18.0019.37 – 19.4619.57 – 19.74

1530

21.20 – 21.3915

23.99 – 24.04

10

24.17 – 24.35

15 1427

44.79 – 46.37

21

51.27 – 51.386 12

57.69 – 57.7415 14

90.32 – 90.65

10

104.79 – 104.85

5

106.70

8

218

6 12

24.05 – 24.111

human

rat mouse

dogco

wch

icken

HSA 14

opossum

Page 16: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.00 – 18.20

26.24 – 27.002 1

30.57 – 30.69

1 7 321 10

41.30 – 41.313 2

105

42.74 – 42.7921

49.08 – 49.1467.35 – 67.49

10

68.18 – 68.749

71.97 – 72.0110

74.28 – 74.3021

74.98 – 74.9810

76.02 – 76.07

30

78.05 – 78.14

8 9

100.08 – 100.161 7

321

10

100.803 2 30 10 ?

41.26 – 41.26

41.38 – 41.4120

20.27 – 20.3817

1

human

rat mouse

dogco

wch

icken

HSA 15

opossum

Page 17: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.16 – 00.1611

02.70 – 02.7414

03.01 – 03.0119

03.11 – 03.19

17

03.43 – 03.43un

16.14 – 16.15

10

16

28.13 – 28.7414

30.90 – 30.9015

31.45 – 31.98

1 7

6 25

19

35.00 – 45.006 12 8 un un

57.33 – 60.242

89.10

19 85

18 1145.52 – 45.55

15

6

1

human

rat mouse

dogco

wch

icken

HSA 16

opossum

Page 18: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

03.77 – 03.859

06.68 – 06.84

19

08.23 – 08.28un

15.58 – 15.7418

16.65 – 16.7819

19.26 – 19.38

14

20.31 – 20.8419

22.00 – 22.2014

25.88 – 26.0819

5

26.31 – 26.4518

26.67 – 26.7419

27.72 – 27.8418

29.51 – 29.7127

33.18 – 33.7119

36.47 – 36.56

19

37.42 – 37.4223

45.71 – 45.77

27

46.60 – 46.603

52.45 – 52.5218

57.50 – 57.811927

59.40 – 59.4765.69 – 67.63 1869.96 – 69.97

9

71.08 – 71.103

73.61 – 73.6218

76.88 – 77.123

79.00

18

19

18

10 11

77.25 – 77.2677.47 – 77.49

318

05.05 – 05.132

7

2

18.18 – 18.3218.63 – 18.70

62626

2

human

rat mouse

dogco

wch

icken

HSA 17

opossum

Page 19: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.57 – 00.9018 18

09.95 – 10.449 17

13.12 – 13.21

7

15.40 – 16.701

32.61 – 32.63

2

39.11 – 40.54Z

42.92 – 43.6214

46.07 – 46.58

7

55.52 – 56.19Z

56.19 – 57.31

1818

63.33 – 65.6813 1

75.9018 18

1

24

2

3

human

rat mouse

dogco

wch

icken

HSA 18

opossum

Page 20: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

01.16 – 01.1828

01.45 – 01.51Z

04.17 – 04.18

7 10

06.94 – 06.97un

17

07.04 – 07.078 9

08.23 – 08.2612 8

08.70 – 08.797

08.81 – 08.90

28

12.44 – 12.508 9

14.75 – 14.7719 8

15.10 – 15.1310

15.97 – 16.047

17

un

24.01 – 32.7016 8

20 7

28

39.68 – 39.8611

41.09 – 41.0924

56.84 – 56.90

7

58.70 – 59.4117

63.70

1

7

1 18un

17

3

1

4

human

rat mouse

dogco

wch

icken

HSA 19

opossum

Page 21: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

02.36 – 02.3920

03.01 – 03.04un

04.18 – 04.624

05.12 – 05.2322

05.97 – 05.973

13.75 – 14.2514

17.46 – 17.503

18.69 – 19.1414

23.35 – 23.373

23.50 – 24.40

24

25.16 – 25.1814

26.20 – 28.0023

3

36.64 – 36.70

13

37.10 – 37.1020

43.49 – 43.6013

43.72 – 43.7819

55.27 – 55.3413

55.42 – 55.603

62.40

3 2

24

13

20

02.40 – 02.581

03.59 – 03.665

1

human

rat mouse

dogco

wch

icken

HSA 20

opossum

Page 22: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

42.30 – 42.4100.00 – 13.30

11 16

43.07 – 43.141

43.40 – 43.6628

44.01 – 44.01

17

44.51 – 44.53

1

45.12 – 45.139

46.90

20

10

31

1

7

4

2

human

rat mouse

dogco

wch

icken

HSA 21

opossum

Page 23: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

00.00 – 14.4017.03 – 17.14

4 6 27 5 1

21.08 – 21.5711 16

23.16 – 23.2820

23.31 – 23.4410

27.48 – 27.4919

5

30.34 – 30.3411

30.83 – 31.1114

5

26 17 15

31.58 – 31.99107

34.27 – 34.3219 8 5

49.607 15

10 1

8

8

3

human

rat mouse

dogco

wch

icken

HSA 22

opossum

Page 24: Additional file 1: Summary of E-painting results for human chromosomes 1-22. The human chromosome coordinates of the breakpoint intervals are given to

16

21

15

6

4

3

2

5

14 26

7

3810

11

8

19

28

17131

30

9

X3212

22

20

31

33

34

Z

18

3523

24

25

36

37

27

29

un

Colour code