ACQUASEAL® COCONUT - Active Concepts, LLC · coconut lipids. • Coconut oil is now making its mark in the personal care market as the more effective alternative to mineral oil:

ACQUASEAL® COCONUT

20742 AcquaSeal® CoconutMoisturization + Pollution Protection + Antioxidant

Product Code: 20742

INCI Name: Cocos Nucifera (Coconut) Fruit Extract

INCI Status: Conforms

Suggested Use Levels: 0.5 – 5.0%

Suggested Applications: Improves Barrier Function, Moisturization, Antioxidant

Solubility: Oil Soluble

• The use of Coconut Water in Health and Wellness Market:• Coconut water is one of the most rapidly growing wellness-oriented beverage• Exotic and has excellent consumer recognition

• Coconut water has an enduring history of use in medical applications:• Isotonic solution – replaces lost fluids & minerals when the body is dehydrated

• Coconut themselves use a very different strategy for moisture retention – coconut lipids.

• Coconut oil is now making its mark in the personal care market as the more effective alternative to mineral oil:• Rich in MCTs – contributing to cellular nutrition• Effective levels of Sterols – structurally similar to cholesterol – an essential

component of proper cell membrane permeability and fluidity


• AcquaSeal® Coconut is derived from the tropical coconut fruit, implementing the coconut’s hydration retention strategy into cosmetic formulations.

• AcquaSeal® Coconut is a sterol extraction which contains a high concentration of medium chain triglycerides (MCTs).

• MCTs are readily metabolized by the skin allowing an increased absorption of vitamins, minerals and amino acids.

• A rich coconut balm, AcquaSeal® Coconut enhances the feel of a formulation and can endow the skin, lips and hair with a silky, light and grease-free texture to help provide hydration and re-lipidize the essential skin barrier.


20742 AcquaSeal® CoconutAvailable Efficacy

• In-vivo Efficacy Studies• 24 Hour Moisturization Assay• Moisturization Assay• Pollution Protection• TEWL Study• Salon Half Head Study

• In-vitro Efficacy Studies• Lipophilic ORAC Assay

20742 AcquaSeal® CoconutMoisturization Assay

Protocol

• Equipment: DermaLab Combo

• Principle of measurement: Conductance, single frequency

• Subjects: 10 (m/f)

• Test area: Volar forearms

• Concentration of active used: 2.0%

• Frequency of application: Twice Daily

Figure 1: Improvements in moisturization following application of test materials after a period of 3 weeks

-3%

168%

138%

122%108%

-2%

29%31% 35% 33%

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t = 0 24 hrs 1 week 2 weeks 3 weeks

Perc

ent (

%) D

iffer

ence

Experimental vs. Untreated Control Experimental vs. Base Lotion

20742 AcquaSeal® CoconutTransepidermal Water Loss (TEWL) Assay

Protocol

• Equipment: DermaLab Combo

• Principle of measurement: Conductance, single frequency

• Subjects: 10 (m/f)

• Test area: Volar forearms


• Frequency of application: Twice Daily

• AcquaSeal® Coconut is capable of reducing TEWL, promoting moisture retentionFigure 2: Improvements in barrier function following application of test materials after a period of 3 weeks

10%11%

12%

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6%

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15%

0%

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t = 24 1 week 2 week 3 weeks

Perc

ent (

%) I

ncre

ase

Experimental vs. Untreated Control Experimental vs. Base Lotion

20742 AcquaSeal® CoconutOxygen Radical Absorbance Capacity (ORAC) Assay

Protocol

• Trolox® was used as the positive control

• Test Quantity: 0.5%, 0.1%, 0.05%

• Fluorescent measurements were taken every two minutes for two hours

• AcquaSeal® Coconut showed antioxidant activity at levels as low as 0.05%

Figure 3: Antioxidant capacities

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50µM Trolox® 6.25µM Trolox® 0.5% AcquaSeal®Coconut

0.1% AcquaSeal®Coconut

0.05% AcquaSeal®Coconut

Antio

xida

nt C

apac

ity (µ

MTE

)

20742 AcquaSeal® CoconutSkin Pollution Protection AssayProtocol

• Volunteers, male and female, between the ages of 23 and 45

• Apply 2 mg of each test material, experimental, control, and untreated on volar forearms

• Lotions were allowed to dry completely before the addition of 5 mg of micronized charcoal

• The micronized charcoal used has a particle size of 2.5 microns (PM 2.5) or less that mimics the small particulates found in polluted air

• Each treatment area was washed five times using deionized water

• Images were taken pre- and post-wash using a dissecting microscope

• The test material consisted of 2% AcquaSeal® Coconut in a Cetaphil Moisturizing for All Skin Types

20742 AcquaSeal® CoconutSkin Pollution Protection Assay

Results

• AcquaSeal® Coconut was able to provide pollution protection as specified by micronized carbon residue

• The small amount of carbon that remains compared to the untreated control indicates the ability of AcquaSeal® Coconut to provide barrier protection against everyday air pollution and slow the extrinsic aging process

• AcquaSeal® Coconut can be used as a skin pollution protection active ingredient

AcquaSeal®Coconut

Lotion Control

Untreated Control

Pre-Wash Post-Wash

Figure 4: Pollution protection assay results

20742 AcquaSeal® CoconutSalon Half Head Study

Protocol

• 5 participants with ethnic hair


• Principle of measurement: Salon professional and volunteer assessed hair characteristics

• AcquaSeal® Coconut demonstrated the ability to smooth the cuticle of the hair, enhance combability, and increase shine

Full head baseline photo of untreated hair Half-head photo of hair treated with controland experimental shampoo/conditioner

Control Experimental

20742 AcquaSeal® CoconutSalon Half Head Study



Control Experimental Control Experimental

AcquaSeal® Coconut is capable of enhancing the shine, smoothness, moisture levels, and overall health and manageability of the hair, making it an ideal ingredient for use in products intended for unruly or ethnic hair types.


Product Code: 20742

INCI Name: Cocos Nucifera (Coconut) Fruit Extract

INCI Status: Conforms

Suggested Use Levels: 0.5 – 5.0%

Suggested Applications: Improves Barrier Function, Moisturization, Antioxidant

Solubility: Oil Soluble

ACQUASEAL® COCONUTActive Concepts, LLCLincolnton, NC. USAwww. activeconceptsllc.com Office: +1 704 276 [email protected]

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ACQUASEAL® COCONUT - Active Concepts, LLC · coconut lipids. • Coconut oil is now making its mark in the personal care market as the more effective alternative to mineral oil: