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Accelerator-based applications and commercial services Ari Virtanen NuPECC mini workshop 13.6.2014

Accelerator-based applications and commercial services

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Accelerator-based applications and commercial services . Ari Virtanen NuPECC mini workshop 13.6.2014 . OUTLINE. 1. Main commercial applications. Radiopharmaceutical isotopes. Testing of space electronics. Microfilters. Customers Revenue. 2. Other applications. - PowerPoint PPT Presentation

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Page 1: Accelerator-based applications and commercial services

Accelerator-based applications and commercial services

Ari Virtanen

NuPECC mini workshop 13.6.2014

Page 2: Accelerator-based applications and commercial services

Testing of space electronics

MicrofiltersRadiopharmaceutical isotopes

1. Main commercial applications

2. Other applications

• EU, ESA and with other collaborators

• Materials physics at Pelletron laboratory

OUTLINE

• Customers• Revenue

3. Future?

4. Conclusions

Page 3: Accelerator-based applications and commercial services

Commercial activityfor

space industry

Page 4: Accelerator-based applications and commercial services

Galactic and extra-galactic heavy ions and protons

We simulate space radiation effects

in satellite electronics

Trapped protons and heavy ions in Van Allen beltsHeavy ions in magnetosphere

Solar flare protons and heavy ions

Page 5: Accelerator-based applications and commercial services

Official test laboratory of ESA since 2005

ESA/ESTEC/Contract No. 18197/04/NL/CP”Utilisation of the High Energy Heavy Ion Test Facility for Component Radiation Studies”Tested satellite electronics in RADEF for ESA, NASA, JAXA (Japan), CNES (France) and for more than 40 satellite companies and organizations

International Space Station Telecommunication satellites Global Positioning System, GPS Mission satellites Earth observation, i.e. EO- satellites

Global warming Weather etc…

ISS

Page 6: Accelerator-based applications and commercial services

Customers

For example; in 2013– 46 test campaigns by 28

individual users– ~25% of K=130 beam time

Page 7: Accelerator-based applications and commercial services

Commercial activityfor

microfilter industry

Page 8: Accelerator-based applications and commercial services

Beam line

105 pores / cm2 109 pores / cm2 0.1 µm 10 µm

to etching

@OxypheN

Irradiation of polymer films

Page 9: Accelerator-based applications and commercial services

Membrane production• Current contract until 2018• Annual income ~260 keur• Annual beam time usage = 15 x 24hours

>100 km irradiated membrane in 4 days

X-section of the foil

Page 10: Accelerator-based applications and commercial services

Example: Use in car industry

Porsche Cayenne

Filters, using Oxyphen RoTrac® capillary pore membrane, remove moisture, vent the headlamp and stop water and dust (c.f. GoreTex)

Modern headlamps are transparent systems with complex thermalcharacteristics; moisture, dust and heat affect function and appearance

Page 11: Accelerator-based applications and commercial services

Commercial activityfor

medical industry

Page 12: Accelerator-based applications and commercial services

Radioisotope production• I-123 project– Development started 1998, commercial 2002– Stopped in 2008 partly due to worldwide market and the

construction work for K-30

• F-18 development project– Started 2007– Stopped in 2013 due to the delays and bad luck

• Substitutive radioisotope project is currently under way…

Page 13: Accelerator-based applications and commercial services

Curing principle:Killing agent, = alpha-emitter, is linked via a chelator to the targeting antibody agent, which seeks tumor cells.

Killing principle:Short-range high-energy α-particles accumulate very effectively their energy to the tumor cells. Killing power of alphas is 120 000 times higher than the long-range low-energy electrons.

Alpha therapy project”Targeted medicine is the future, from which the alpha-radio-immunotherapy is an ultimate example”

Memorial Sloan Kettering Cancer Center

Page 14: Accelerator-based applications and commercial services

Crew

Arto JavanainenPostdoctoral researcher

Mikko RossiLaboratory engineer

Jukka JaatinenLaboratory engineer

Heikki KettunenLaboratory engineer

Ari VirtanenResearch director

Taneli KalvasPostdoctoral researcher

Alexandre BosserGraduate studentfrom MU2

Page 15: Accelerator-based applications and commercial services

2004 2005 2006 2007 2008 2009 2010 2011 2012 20130 €

100,000 €

200,000 €

300,000 €

400,000 €

500,000 €

600,000 €

700,000 €

800,000 €

900,000 €OTHERMEDICALSPACE OTHERSMEMBRANE

Annual revenue

In 2012 – 2013: 7 publications in peer reviewed journals and 2 PhDs

Page 16: Accelerator-based applications and commercial services

Our concept:”Business from Top-Research” won in 2011 the annual entrepreneurship competition among 13 Finnish universities

Commercial break

Page 17: Accelerator-based applications and commercial services

Other applications

Page 18: Accelerator-based applications and commercial services

• Main research fields– Fundamental ion-matter interactions (cross sections, stopping forces, straggling)– Materials research applications

• Facility– 1.7 MV Pelletron accelerator (in Jyväskylä since 2006)

• Three ion sources, four beam lines• H, He, Cl, Cu, Br, I, and other heavy ion beams, 0.2 – 20 MeV

Materials physics at Pelletron laboratory

Page 19: Accelerator-based applications and commercial services

Functionalized ion tracksEnhanced electron multiplication in ALD coated pores

Thin films processing and applications

ALD tool

Microfluidic chip

Atomic layer deposition (ALD)Oxides, nitrides, carbides, fluorides, sulphides and metals with excellent control of film thickness and high conformality for 3D structures

Lithography with proton beam writingLarge area exposures for high-aspect ratio structuresMicrofluidic chips for borrelia infection diagnostics

Page 20: Accelerator-based applications and commercial services

External PIXE

Collaboration with RECENART = Research Center for Art

Page 21: Accelerator-based applications and commercial services

• SkyFlash (262890 EU-FP7 Project) http://www.skyflash.eu/ – development of a RadHard by design (RHBD) methodology for non-volatile

flash memories– 84 keur

• Technical assessment project for ESA – “Effects of the ion species and energy on the oxide damage and SEGR failure”– 100 keur addition to the ESA’s basic funding

• Close collaborations with – Universities (Montpellier2 and Vanderbilt)– Sandia National Labs– STMicroelectronics

Other radiation testing activities

Page 22: Accelerator-based applications and commercial services

Future?

Page 23: Accelerator-based applications and commercial services

New 18 GHz ECRIS (HIISI)

• Higher energies for heavy ions up to 15 MeV/udeeper penetration in siliconirradiations in air with possibility to tilt

• 300 keur from ESA for development RADEF competitive with e.g. Texas A&M Univ.

Page 24: Accelerator-based applications and commercial services

HORIZON 2020

• Proposals for H2020-COMPET-2014 (RADEF as partner)1. SPES (SOI PLL for Earth hostile environment and Space applications)2. SOLIS (SOI Library for Sapce Applications)3. SpaceMIST (Space Mixed Signal Circuits and Technologies)4. R2RAM (Radiation Hard Resistive Random-Access Memory)5. LIRARSUP (Light weight, Radiation Resistant SUPerconductiong

wires for space applications)

• 1-2 projects are expected to pass• approx. 100 keur per project for RADEF

Page 25: Accelerator-based applications and commercial services

Electron LINAC (Varian)• Energetic electrons for radiation hardness assurance

(RHA) testing• 100 keur from ESA• Ee = 6-18 MeV• JUICE-mission

(Jupiter Icy Moon Explorer)– “The most dominant trapped particle constituents at Jupiter

are electrons with energy in the 1 – 100 MeV range.” • All ESA’s MEO-satellites (2000 – 35 000 km)

– Navigation (GPS), communication, and geodetic/space environment science

– Van Allen electron belt (tens of MeV)

NAS

A/JP

L

Page 26: Accelerator-based applications and commercial services

Low energy protons for RHA• Stopping of muons vs. protons

• State of the art technologies (< 65 nm) – errors due to direct ionization of protons Ground effects due to muons?

• RADEF’s graduate student working on this

B. S

iera

wsk

i, Va

nder

bilt

Uni

v.

Page 27: Accelerator-based applications and commercial services

CoE SAB meeting 27

Conclusions

• RADEF’s activity is going strong– firm client base (space industry and Oxyphen)

• approx. 600 keur annually– strong support from ESA

• 300 keur for HIISI (2015-16)• 100 keur for high energy electrons (2015-16)• continuing basic contract 240 keur for 2014-15

– International collaboration (VU, UM2, Sandia, STM)– partner in EU-FP7 project – partnering in five H2020 proposals

• Radioisotope production project under way

8.5.2014

Page 28: Accelerator-based applications and commercial services

2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 20170 €

200,000 €

400,000 €

600,000 €

800,000 €

1,000,000 €

1,200,000 €

1,400,000 €

1,600,000 €OTHEREst. MEDICALMEDICALEst. SPACESPACE OTHERSMEMBRANEESA

Conclusions – the three scenarios?

+ K30

=Bold

?

+ Linac/Pelletron=Likely?

25% K130=Cautious?

Commercialisation of K-30 is needed!

Page 29: Accelerator-based applications and commercial services

Thank you

for your attention