ACB Bio-Chelate 5 PF

Tomorrow’s Vision… Today!®

Skin & Hair Conditioning, Nourishing

ACB Bio-Chelate 5 PF

*20339PF – ACB Bio-Chelate 5 PF

Product Code: 20339PF

INCI Name: Water & Saccharomyces/Zinc Ferment & Saccharomyces/Copper Ferment & Saccharomyces/Magnesium Ferment & Saccharomyces/Iron Ferment & Saccharomyces/Silicone Ferment INCI Status: Conforms

Suggested Use Level: 0.5 - 5.0%

Suggested Applications: Skin & Hair Conditioning, Nourishing

Minerals: Skin & Hair Care

• A growing trend!

o Improve the appearance of the skin: o Damage o Inflammation o Wrinkles

o Vitamins & minerals are perceived as health promoters by

consumers

• Stress depletes nutrients

• Minerals • Just like vitamins, they play a key role in overall health • Are constituents of the hair, bones, teeth, muscle, blood, soft

tissues & nerve cells • Minerals have many functions:

• Zinc

• Enzymatic activity, antioxidant, wound healing, protein synthesis, cellular function

• Copper

• Cofactor, utilization of iron, elastin, keratin, enzymatic activities

Minerals: Skin & Hair Care

• Magnesium • Fatty acid & Vitamin C metabolism, neuromuscular activity

• Iron

• Helps red blood cells deliver oxygen, support the immune system, required for energy production, protein formation & cell maturation

• Silicon

• Protein matrix construction, structure of connective tissue, bone development

Minerals: Skin & Hair Care

ACB Bio-Chelate 5 PF: What is it?

• A mineral glycopeptide complex containing 5 essential minerals, which are fermented with yeast • Consisting of:

Zinc

Copper

Magnesium

Iron

Silicon

ACB Bio-Chelate 5 PF: Why Fermented Minerals?

• Compared to inorganic salts & synthetically chelated minerals, fermented minerals have increased bio-availability • Cells can recognize & use the minerals

• Enhances efficacy

• Coincides with trend for natural ingredients

ACB Bio-Chelate 5 PF: Benefits to the skin?

• Enhances Barrier Function

• Provides Anti-Inflammatory Effect

• Increases Growth Factor Expression

• Decreases Stress Related Factors

• Increases Cellular Energy Production

ACB Bio-Chelate 5 PF: Benefits to the hair & scalp?

• Smoothes the cuticle of physically & chemically damaged hair

• Research demonstrates minerals penetrate deep into the hair

• Does not create buildup that weights hair down

• Increases hydration to minimize dryness, which can cause flaking

• Enhances health of the scalp

In-vivo Efficacy Data: ACB Bio-Chelate 5 PF

Hair Smoothing Properties

1. European blonde hair tresses were damaged by a 2X-bleach/wave process

2. Individual hair fibers were cut into equal halves to produce six hair strands. • Three hair strands function as the test materials & the remaining

three functioned as controls 3. The three damaged test fibers were treated with 100% ACB Bio-

Chelate 5 PF & allowed to dry

4. Scanning Electron Microscopy (SEM) was utilized to observe the surface architecture of the hair strands

Results

• Scan Electron Microscopy images illustrate the smoothing benefits of ACB Bio-Chelate 5 PF on the hair shaft

• The images on the right appear significantly smoother & healthier

• SEM results indicate that ACB Bio-Chelate 5 PF can smooth the cuticle of physically & chemically damaged hair

Hair Smoothing Properties

In-vivo Efficacy Data: ACB Bio-Chelate 5 PF

Protocol

• Equipment: DermaLab Combo

• Principle of measurement: Ultrasound Probe

• Subjects: 10 (m/f)

• Test area: Volar forearms

• Concentration of active used: 2.0%

• Frequency of application: Twice Daily Figure 1: Improvements in skin density following application of the test materials after a period of 3 weeks.

Skin Density Comparison

In-vitro Efficacy Data: ACB Bio-Chelate 5 PF

0.00%

2.00%

4.00%

6.00%

8.00%

10.00%

12.00%

14.00%

16.00%

t = 24 1 week 2 week 3 week 4 week

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Experimental vs. Untreated Base Lotion vs. Untreated Experimental vs. Base Lotion

Figure 2. Antioxidant capacity of ACB Bio-Chelate 5 PF.

ORAC Assay Protocol

• Trolox was used as the positive control

• Solutions were prepared at two concentrations, as a reference

• Florescent measurements were taken every 2 minutes for 2 hours

• ACB Bio-Chelate 5 PF showed antioxidant activity

In-vitro Efficacy Data: ACB Bio-Chelate 5 PF

101

14

86

18

12

0

20

40

60

80

100

120

100µM Trolox 12.5µM Trolox 0.5% ACB Bio-Chelate 5 PF

0.1% ACB Bio-Chelate 5 PF

0.05% ACB Bio-Chelate 5 PF

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DNA Microarray

In-vitro Efficacy Data: ACB Bio-Chelate 5 PF

• Monitors expression levels of thousands of genes simultaneously

• Each spot contains a unique DNA fragment with a known sequence

• Labeled mRNA from the test sample binds to the spot containing its homologous DNA fragment

Results

• DNA Microarray had 21,629 different DNA fractions

• Results illustrated that 1,155 genes were altered by more than 30%

• 591 genes were down-regulated

• 564 genes were up-regulated

• Conditions: 24 hour exposure to 5.0% ACB Bio-Chelate 5 PF in water

DNA Microarray Benefits

In-vitro Efficacy Data: ACB Bio-Chelate 5 PF

• Enhances barrier function

• Provides anti-inflammatory effects

• Increases growth factor expression

• Decreases stress related factors

• Improves cellular energy production

ACTIVE CONCEPTS LLC

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