Academician Prof/Dr  Hamdy El-kabarity  M.D.

WINNER OF ERNST THEODOR RIPPMANN MEDAL DE ONOARE -2008

Feto-Maternal Immunologic Dialogue Feto-Maternal Immunologic Dialogue Immunologic Hypothesis for the Immunologic Hypothesis for the

Etiology of EPH SyndromeEtiology of EPH Syndrome

INTERCONTINENTAL OGASH ACADEMY - CSPP

http://gestosis.ge/eng/26_4.php

Ain Shams Univeristy Ain Shams Univeristy

Cairo  EgyptCairo  Egypt

PRIZEWINNER OF PROFESSOR IOSEB JORDANIA INTERNATIONAL PRIZE-2007

In part I and part II who described the immunologic basis for In part I and part II who described the immunologic basis for the evolution of EPH gestosis .1st described for a syndrome the evolution of EPH gestosis .1st described for a syndrome of collection of symptoms and signs that occur in:of collection of symptoms and signs that occur in:

1.1.Man kind and high apesMan kind and high apes2.2.Only during pregnancyOnly during pregnancy3.3.Once it occurs in 1 st pregnancy, it has tendency to re -occur Once it occurs in 1 st pregnancy, it has tendency to re -occur in the succeeding pregnancy i.e.the 1 st pregnancy may be a in the succeeding pregnancy i.e.the 1 st pregnancy may be a test of compatability,  incompitabaility  of fetus  as an test of compatability,  incompitabaility  of fetus  as an allograft.allograft.

4. The immunlolgic challenge between the fetus and placenta as an allograft and his hosting mother with the  proved  imbalance  of Th1/Th2 - interleukin 18/12 in normal EPH gestostic pregnancy. 

5. The station  of vascular  endothelial damage  we all reached  now is not the final  station more logically pointig to the changing point to another train.The role of the father  DNA as foreign  protein  to maternal immune  systems carried  by the  deported chorionic villi may lead to the immmunologic imbalance as the respnose  to this identification. 

6. This  immunologic  disrupted relation between the mother  and the placenta and fetus , this may  be to  the picture of chorionic endothelial damage that mimic to that appear in the rejected allograft.

Also the antiphospholipid  syndrome during pregnancy of abortion, repeated abortion, idiopathic placental insufficiency and toxaemias of pregnancy may be rings of the chain.

http://gestosis.ge/eng/26_5.php

90 CME credits Intercontinental Academy of Medical-Social Sciences (IAMSS) OGASHNumber 90 (ninety) IAMSS International CME credits are recognized by Post Congress IAMSS OGASH Awards Commission Chairperson, IAMSS Presidium Chairperson, Hon. Academician of OGASH, Academician Secretary of OGASH Prof / Dr IRMA de LUCA BRUNORI MD., PhD.

Verified the achievement & award of the proceeding author Hamdy El-kabarity Post Congress IAMSS OGASH Awards Commission Chairman,

IAMSS Presidium Chairperson,Hon. Academician of OGASH

Academician Prof./Dr. Malkhaz Mizandari MD., PhD. CERTIFIES

The achievement of n. 90 International credits (IAMSS)