ABNORMAL SMEAR Prepared by : Stephanie N. Ammari

Headlines

• Pap smear :

1. Definition

2. Importance .

3. Procedure .

4. Screening .

• Cervix : anatomy & histology .

• Abnormal Smear :

Cervical Histology

Transformation Zone

• Is defined as the area between the original SCJ & the

current SCJ where the epithelium changes from columnar

epithelium to squamous epithelium over time .

Pap Smear

• Developed by Dr. George N. Papanicolaou in 1940s .

• What is it ???

• Purpose …

• Importance …

Procedure ( video )

Normal Cervical Cytology

Abnormal Smear …

Abnormal cervical cytology shows squamous cells at

different stages of maturity ( dyskaryosis ) .

Cervical Intraepithelial Neoplasia

( CIN )

Low grade CIN High grade CIN

CIN 1 CIN 2,3

Spontaneous regression of

not uncommon & is likely to

occur through the patient’s

own cell mediated immunity

Requires treatment

Management of the results …

• Thank you …