ABERRATIONS IN PATIENTS IMPLANTED WITH LIGHT

ADJUSTABLE INTRAOCULAR LENSES

Pablo Artal, Encarna Alcón, Eloy Villegas, Carmen Cánovas, Elena Rubio*, José M. Marín*LABORATORIO DE OPTICA, UNIVERSIDAD DE MURCIA, SPAIN

* Hospital Virgen de la Arrixaca, Murcia, SPAIN

Supported by:

Reserch funding and consulting reimbuserment provided by Calhoun Vision, USA

Best focus (0 D, 0 D)

Refractive errors (defocus & astigmatism) produce the most

deleterious impact in vision after cataract surgery

Refractive error (1 D, 1 D)

Spatially resolved irradiation

h"lock-in"

h

Light adjustable intraocular lenses (LALs)* allow nearly PERFECT refractive outcomes and improved

quality of vision after cataract surgery

*

Surgery

Corneal stabilization

Two weeksadjustment + lock-ins

+

LALs procedure:

64 patients implanted with LALs have been carefully measured with

an objective WAVEFRONT approach

for refraction and aberration control through the whole

treatment process

Post_1ºadjustment Post_lock-in1 Post_lock-in 2Pre adjustmenttreatment lock-ins

Example of eye’s (all) aberrations

Post_3months

stability

Induced wavefront

by treatment

Effect of light profiles in LAL’s aberrations

Hyperopic Myopic Astigmatic light treatments…

LAL = eye - cornea(Artal and Guirao, Opt.Lett., 1998; Artal et al., JOV,2001)

-=

= -?

M N H1 H2 HA MA1 MA20.00

0.05

0.10

0.15

0.20

0.25

0.30

0.35

R

MS

(m

)

4mm pupil

INDUCED ABERRATIONS BY LIGHT TREATMENT

0.00

0.20

0.40

0.60

0.80

1.00

1.20

1.40

1.60

Pre adjustment Adjustment 1 Post Lock-in 2

Corr

ecte

d V

A H1

H2

HA

NN

M

Aspheric

MA1

MA2

Bes

t co

rrec

ted

VA

Impact of induced aberrations by

treatment in visual acuity

Eye

Internal

Cornea

after one month

Eye

Internal

Cornea

aftertreatment

Po

st

loc

k-i

n 2

3 m

on

th

6 m

on

th

1y

ea

r0.0

0.1

0.2

0.3

0.4

0.5

0.6

RMS

mic

ron

s

Stability of the adjustable IOLs after lock-in: changes in LAL’s wavefront?

i) The light adjustment profiles induced small amounts of high order aberrations, except for the myopic astigmatism and myopic treatments

ii) These induced aberrations did not compromise visual acuity

iii) The aberrations in the LALs remained nearly constant up to 1 year post-surgery

iv) These results indicate the potential ability of LALs to effectively control the eye´s aberrations

Conclusions