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4/5/2011April 4, 2011CADTH Presentation
Abbott Point of Care Agenda
• APOC / i-STAT overview
• Benefits of i-STAT
• i-STAT in Canada
4/5/2011April 4, 2011CADTH Presentation
Abbott Point of Care• 1,300+ employees globally
• 2010 Sales ~ $273MM
• Manufacturing and Research and Development headquartered in Ottawa, Ontario
• Plant in Ottawa made 35MM Cartridges in 2010
• Extensive R & D Investment
• Headquarters in Princeton, NJ
• Over 6,000 worldwide i-STAT customers
• Installed base of ~ 38,000 i-STAT analyzers
4/5/2011April 4, 2011CADTH Presentation
The i-STAT is…SIMPLICITY
•One Piece Analyzer and Cartridge Comprise Test Syst em
•Designed for use by non-lab personnel
•Nurse, RT, Perfusion, Tech
4/5/2011April 4, 2011CADTH Presentation
The i-STAT System ProvidesThe Most Comprehensive Menu of Tests
4/5/2011April 4, 2011CADTH Presentation
The many steps involved:
• Slow lab results
• Delay diagnosis and treatment
• Allow ample opportunity for variances and handoffs that can lead to patient errors
Traditional Blood Analysis Process Is Complex and Time-Consuming
4/5/2011April 4, 2011CADTH Presentation
The i-STAT System Streamlines the Traditional Blood Analysis Process
• Real-time results help speed diagnosis and disposition of patients1
• Helps reduce potential for error by decreasing the amount of time required to collect, process, and report results with fewer handoffs
References: 1. Ryan RJ et al. Ann Emerg Med. 2008 Aug 6. (Epub ahead of print).
4/5/2011April 4, 2011CADTH Presentation
IMPACT OF i-STAT
Accelerate Treatment• Expedite Patient Care• Improved Outcomes• Reduced LOS• More Patient Interaction• Decreased Lab TAT• Process Efficiency
CLINICIANSComplement the Lab• Reduced STAT Workload• Full EMR Integration• Standardized Platform• Facilitates Compliance• Facilitates Training
LAB
Summary of Benefits
Patient Focus• Faster Treatment • Improved Outcomes• Reduced LOS• Reduced Blood Volumes• Reduced Transfusions• Process Efficiency• Improved Satisfaction
PATIENTPositive ROI• Expedite Patient Care• Improved Outcomes• Reduced LOS• Increased Satisfaction• Enhanced Lab Value• Process Efficiency
HOSPITAL
4/5/2011April 4, 2011CADTH Presentation
Critical Challenges Facing Canadian Emergency Departments
Emergency Departments (EDs) across the nation are facing unprecedented challenges in maintaining a high level of patient care,
improving department efficiencies, and remaining financially viable.
• Cost
• Overcrowding
• Staff Shortages
• Patient Safety / Satisfaction
• Downstream costs
4/5/2011April 4, 2011CADTH Presentation
The 80/20 Rule: ED Visits Admit vs. Non Admit
Non Admit
Admit
MI Trauma
Rapid Response
Chest pain
Abdominal pain
Syncope
Shortness of Breath
Vomiting/Diarrhea
GI
Overdose
Cough & Fever
National Hospital Ambulatory Medical Care Survey: 2007 Emergency Department Summary found electronically: www.cdc.gov/nchs/data/nhsr/nhsr026.pdf
4/5/2011April 4, 2011CADTH Presentation
The i-STAT System:A Comprehensive ED Platform
The most common tests for the most common ED patien ts
On One Platform
4/5/2011April 4, 2011CADTH Presentation
ED Visits Leading Reasons and i-STAT cartridge to help aid in Dx
0 2000 4000 6000 8000 10000
Shortness of Breath
Back Symptoms
Headache
Cough
Fever
Chest Pain
Stomach Pain
ED Visits (in thousands)
Pitts SR, Niska RW. Xu J, et al. National Hospital Ambulatory Medical Care Survey: 2006 Emergency Department Summary. Natl Health Stat Rep. 2008;7:1-40.
CHEM8+, CG4+
Troponin , CK-MB, BNP
CHEM8+, CG4+
BNP
4/5/2011April 4, 2011CADTH Presentation
• ED Arrival to ED Departure (ED length of stay)
• Door to result (ie. Troponin)
• ED Bed to result
• Door to disposition decision
• Disposition to leaves ED
• Door to doctor / Physician Interaction Time
Impact on ED Metrics
4/5/2011April 4, 2011CADTH Presentation
The i-STAT System Shortens ED Length of Stay and Door-to-Disposition Times
• In patients randomized to point-of-care testing:
� 38.5 minute decrease in emergency department (ED) length of stay
� 45 minute decrease in time-to-disposition
• Demonstrated in a trial comparing the effect of the i-STAT System versus traditional laboratory testing on length of stay in a pediatric ED
Median ED Length of Stay
0
50
100
150
200
250
Central Lab i-STATM
inut
es
The i-STAT ® Solution
204204
165.5
Reference: Hsiao AL et al. Ped Emer Care. 2007;7:457-462.
4/5/2011April 4, 2011CADTH Presentation
i-STAT Helps EDs Comply With Guideline-Recommended Turnaround Times (TATs)
0
10
20
30
40
50
60
70
80
90
100
Proportion of assays with TAT <30minutes
Proportion of assays with TAT <60minutes
.
Across all centers, i-STAT Troponin testing met the recommended TAT
guideline of 60 minutes nearly 100% of the time
Across all centers, i-STAT Troponin testing met the recommended TAT
guideline of 60 minutes nearly 100% of the time
DISPO- ACS: Multicenter Randomized Controlled Trial Comparing Central Laboratory and Point-of-Care Cardiac Marker Testing Strategies in the ED
Proportion of assays (%) i-Stat POC
Laboratory
Ryan RJ, et al. Ann Emerg Med. .2008. Aug 6. 10.1016/j
3
87
53
98
Number of results TAT<30 minutes
Number of results TAT<60 minutes
Ryan RJ, et al. Ann Emerg Med. .2008. Aug 6. 10.1016/j
4/5/2011April 4, 2011CADTH Presentation
Increased Length of Stay Reduces Patient Satisfaction
• Patient satisfaction decreased as time spent in the emergency department (ED) increased
– Fell sharply after 2 hours– Fell with each additional
hour• Demonstrated in a survey
of 1.5 million patients treated at 1,656 U.S. EDs nationwide between January 1 and December 31, 2007
•
Patient Satisfaction, Time Spent in the ED
65
70
75
80
85
90
95
<1 1–2 2–3 3–4 4–5 5–6 >6
Time (hours)
Pat
ient
sat
isfa
ctio
n (%
)
Reference: Press Ganey Associates. Emergency Department Pulse Report. 2008.
Critical Challenges Facing the ED
4/5/2011April 4, 2011CADTH Presentation
Ross Memorial Hospital - Ontario
• NEW TEST HELPS DIAGNOSE HEART ATTACK PATIENTS IN MIN UTES
• March 23, 2010, LINDSAY, Ont. — Every minute counts when treating heart attack victims, so decreasing the time spent waiting for t est results can be life-saving .
• The i-STAT system involves a hand-held device which measures the troponin level in a patient’s blood with lab-quality results. Troponin is a chemical that is released in the blood when a person is experiencing a heart attack. Using conventional lab tests, it can take up to an hour to get results; with the i-STAT system, the physician gets the result in approximately 7-10 minutes.
• The sooner physicians are able to diagnose that a p atient has had a heart attack, the sooner treatment can begin, reducing the severity o f damage to the patient’s heart muscle.
• “With the i-STAT System, we can offer patients faste r testing and, potentially, faster treatment when every minute counts,” stated Dr. Leo n Lerm, Chief of Emergency Medicine at RMH. “This will not only build on our E mergency department’s efficiency, but also enhance our patient care.”
• RMH is the first hospital in the Central East LHIN to trial this Canadian product. Funding for the trial was provided by the CE LHIN through the P ay for Performance initiative .
• 95% of patients tested with i-STAT met the Pay for Performance benchmark capturing $19,500 of P4R funding over the course of 6 days.
4/5/2011April 4, 2011CADTH Presentation
Central East LHIN
• “If a hospital would like to submit a P-4-R request for i-STAT, the CE-LHIN has no problem in supporting that venture. We have supported it once (RMH) and would be happy to do so again.”
• ~ ER / ALC Performance Lead
• CE LHIN
4/5/2011April 4, 2011CADTH Presentation
Calgary Rural Lab call back reduction study
• Purpose: To invest the financial impact of utilizing i-STAT to reduce the number of call-backs of laboratory staff during off hours for STAT lab testing.
• Background: 9 sites of a rural health authority is spending nearly $900,000 paying for lab personnel to return off hours to support with lab testing. Paid for 4 hours every time they are called in.
• Study began in late 2010. Nursing staff trained to run the i-STAT in order to aid patient treatment while reducing costs.
• So far an observed reduction of 42% in laboratory call backs.
• 42% of $900,000 is $378,000 saved while providing better more expedient care.
4/5/2011April 4, 2011CADTH Presentation
What else can i-STAT do…
• Improve patient outcomes
• Decrease length of stay
• Reduce transfusions
• Improve throughput
• Reduce process costs
• Improve staff satisfaction
• Reduced Laboratory call back costs
• Reduction in inter-facility transport costs
• Reduce AMA and LWOS
4/5/2011April 4, 2011CADTH Presentation
Scope of Services – Emergency Department
• Consultation and Collaboration in development of a business case for an ED process improvement
– Detailed (step by step) analysis of flow and throughput
– Financial Impact Analysis linked directly to account’s key metrics
– Tracking and evaluation of metric improvement post implementation
– Assistance in application of most current clinical guidelines
– Outside Consultants on contract for analysis service
4/5/2011April 4, 2011CADTH Presentation
Innovations in Menu Expansion
Testing for consideration
ββββ-hCG
hs-cTnI
Mg
Mg/Phos
NGAL
TSH
PSA
dDimer
PTH
aPTT
4/5/2011April 4, 2011CADTH Presentation
i-STAT in Canada
• 345 Customers
• $4.0MM in 2010
• Use Models
–Lab back up device
–Rural lab replacement device
–Niche application
• Reasons why…
–Lack of visibility and focus – Abbott
–Lack of Canadian i-STAT Financial Impact
–Laboratory resistance