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A WIRELESS- IMPLANTABLE MICRO SYSTEM FOR CONTINUES BLOOD GLUCOSE MONITORING
ANOOP PRoll No:07Reg. No:CTAHEEC013
ABSTRACT
• Remotely powered implantable micro system • Consists of a micro fabricated glucose
biosensor flip-chip bonded to a transponder chip
• Transponder chip measures the output signal of the glucose biosensor and transmits to the external reader
• Chip can measure the sensor output current ranging from 1 nA to 1 A
LITERATURE SURVEY
1. NON-CONTINOUS BLOOD GLUCOSE MONITORING • Consist of a blood glucose meters• small drop of blood is needed to place on
test strip
LITERATURE SURVEY
2. Continues wired blood glucose monitoring• Used conventional electrochemical glucose
sensors• Large sizes• Wired
DESIGN
DESIGN
• Microfabricating the glucose sensor• Inegrating all the interfacing circuits into a
integral chip(TRANSPONDER CHIP)• Attaching the microfabricated glucose sensor
to the transponder chip using flip chip bonding
SYSTEM OVERVIEW AND FUNCTIONING
SYSTEM OVERVIEW AND FUNCTIONING
• Monitoring system consisting of an implantable microsystem and an external reader.
• Microsystem measures the blood glucose concentration and transmits the measured data to the external reader
GLUCOSE SENSOR
• Amperometric electrochemical biosensor• Consists of three electrodes: 1)a working electrode(WE) 2)a reference electrode(RE) 3)a counter electrode(CE)
ELECTRODES
1. WORKING ELECTRODE• Act as a surface on which the electrochemical
reaction takes place between the glucose and an enzymatic layer
• It catalyzes the oxidation of glucose to gluconic acid
ELECTRODES
2. REFERENCE ELECTRODE• The reference electrode is used to measure the
solution (blood or interstitial fluid) potential
ELECTRODES
3. COUNTER ELECTRODE• An inert conductor (gold) that supplies the current
required for the electrochemical reaction
TRANSPONDER CHIP
1. RF FRONT-END BLOCK
TRANSPONDER CHIP
2. DATA-ACQUISITION
EXTERNAL READER
ADVANTAGES
• Small size of the implant• No need of oxygen• Use of passive telemetry link
CONCLUSION
• Miniaturization procedure for a wireless-implantable microsystem for continuous blood glucose monitoring
• Low cost procedure• Microsystem implanted just underneath the
skin
REFERENCES
• IEEE Trans.Biomed. Eng., vol. 35, no. 7, pp. 526–532, Jul. 1988.
• IEEE Trans. Biomed.Eng., vol. 41, no. 10, pp. 937–942, Oct. 1994.
• Biosensors Bioelectron., vol. 10, pp. 485–494, 1995
THANK YOU