A R LIFE SCIENCES PRIVATE LIMITED

COMPANY PROFILE

v Established in 1996… as Calcium Chloride manufacturer (A R CHLORIDES)

v Shifted to Manufacturing of intermediates in 2004.v Name Changed to A R LIFE SCIENCES PVT LTD in 2008

(Unit 1).v Unit 2 Acquired Dymes Pharmachem Ltd. In 2014; v Name Changed to A R LIFE SCIENCES PVT LTD (UNIT

2)from 1st December 2016.v Located in Jeedimetla, Hyderabad

v Mainly manufacture Intermediates and API’s for pharmaceutical use

v Major portion of business through contract manufacturing.

DIRECTORS

Founder & Managing Director:Mr. K. SUBBA REDDYv Worked in Dr Reddy’s for almost 20 years since

inceptionv Looks after the financial side.

Executive Director: Mr. K. KRISHNA CHAITANYAv B Tech from Indian Institute of Technology (IIT) Roorkee

and Masters from Iowa State University, USAv Marketing and Overall operations

VISION

To be a global player

in the field of

Pharmaceutical

Intermediates and

API’s.

DRIVING FORCE

v Quality and Service

v Innovation and Research

v Strategic Partnerships

v Transparency In operations

v Commitment coupled with determination,

dedication and discipline

PLANT (UNIT-1)

PLANT (UNIT-2)

NAME Designation Department Experience

K .SUBBA REDDY Managing Director -- +30 Years

K.KRISHNA CHAITANYA

Executive Director OverallOperations

+10 Years

CH. SHYAMSUNDER HEAD – R&D R&D +20 Years

B. RAMI REDDY GM - Plant Production +30 Years

K. BHASKAR REDDY HEAD - QA QA +15 Years

KEY COMPANY PERSONNEL

EMPLOYEES LIST

UNIT 1 UNIT 2TOTAL EMPLOYEES 58 68PRODUCTION 20 25QUALITY ASSURANCE 06 05QUALITY CONTROL 16 14WAREHOUSE 04 03MAINTENANCE 09 16H R & ADMIN 02 05SAFETY & ENVIRONMENT 01

LIST OF FACILITIES (UNIT 1)

¢ WAREHOUSE – RAW MATERIAL & ENGINEERING ¢ ADMIN ¢ QUALITY BLOCK (QA & QC)¢ PRODUCTION BLOCKS – 2 ¢ ETP with MEE.¢ UTILITY AREA¢ PROCESS WATER SYSTEM

LIST OF FACILITIES (UNIT 2)

¢ WAREHOUSE – RAW MATERIAL & ENGINEERING ¢ ADMIN ¢ QUALITY BLOCK (QA & QC)¢ PRODUCTION BLOCKS – 3¢ One Dedicated Block to carry out High Pressure

Reactions (Upto 32Kg), Cryogenic Reactions (Upto - -80 Deg C) Available.

¢ CLEAN ROOM - 2 ¢ ETP ¢ UTILITY AREA¢ WATER SYSTEM (DM WATER & PROCESS WATER)

INFRASTRUCTURE

UNIT 1 UNIT 2TOTAL PLANT AREA 5989.30 Sq. Meters 5466. Sq. Meters

TOTAL No OF REACTORS 22 (GLRs – 06 ; SSR – 16)

32 (GLRs – 13 ; SSR – 19)

TOTAL REACTION VOLUME CAPACITY

~33 KL ~55KL

SITE APPROVAL STATUSTYPE OF Accrediation UNIT 1 UNIT 2

Factory License √ √ISO 9001: 2015 √ √

USFDA √ ---JAPAN √ ---

WHO GMP --- √GMP --- √

TSPCB √ √

WAREHOUSE (UNIT 1)

WAREHOUSE - IIWAREHOUSE - I

SAMPLING & DISPENSING AREA SOLVENT TANK

WAREHOUSE (UNIT 2)

WAREHOUSE

Ø Raw Materials handling is being controlled with adequately definedprocedures.

Ø Warehouse provides separate areas with respect to status ofmaterials, viz., Under Test, Approved and Rejected and are stored atAppropriate Designated Areas.

Ø Solvents received in Bulk are Stored at Solvent Tank Farm.

Ø Liquid raw materials received in Drums is stored at Separate Area.

LIST OF MAJOR PRODUCTION EQUIPMENT (UNIT 1)PRODUCTION BLOCK - 1:

REACTORS : 20 (GLR – 06; SSR – 14) – Capacity Min : 0.1 KL Max: 3.0 KL).CENTRIFUGE : 07 Capacity: 36” – 6 No's; 48” – 1 No. VTD : 01 Capacity : 24 TRAYS RCVD : 01 Capacity : 200 LTD : 05 Capacity : 48 TRAYSMulti Miller : 01 Capacity : 250 Kg/hr.

PRODUCTION BLOCK - 2:

REACTORS : 02 (SSR – 02 ) – Capacity : 1 KL.Dedicated for Hydrogenation and Workup.

LIST OF MAJOR PRODUCTION EQUIPMENT (UNIT 2)PRODUCTION BLOCK – 1 (B BLOCK):

REACTORS : 21 (GLR – 10; SSR – 11) – Capacity Min : 0.6 KL Max: 5.0 KL).CENTRIFUGE : 07 Capacity: 36” – 3 No's; 48” – 3 No. , 24” - 1No.VTD : 01 Capacity : 12 TRAYS RCVD : 01 Capacity : 500 LTD : 05 Capacity : 48 TRAYS – 4 No.s & 96 TRAYS – 1 No.

PRODUCTION BLOCK – 2 (C BLOCK):

REACTORS : 06 (SSR – 06 ) – Capacity Min : 1.0 KL Max: 3.0 KLDedicated for Hydrogenation and Workup.

LIST OF MAJOR EQUIPMENT CLEAN ROOM - UNIT 2CLEAN ROOM 1 &2:

REACTORS : 05 (GLR – 02; SSR – 03) – Capacity Min : 0.25KL Max: 2.0KL).CENTRIFUGE : 02 Capacity: 36” RCVD : 01 Capacity : 350 LTD : 03 Capacity : 48 TRAYS VTD : 01 Capacity : 06 TRAYSSIFTER : 02 Capacity : 30” MULTI MILL : 02 Capacity : 01 No. 50 Kg & 01 No,: 250 KgMICRONIZER : 02 Capacity : 5 Kg & 100 Kg

QUALITY CONTROL (UNIT 1)

WET LAB

HPLC LAB

CONTROL SAMPLE ROOM

GC LAB

Name of the Instrument No.s

HPLC with VWD detector (AGILENT) 01

HPLC with VWD detector (SHIMADZU) 01

GC with Liquid Injectors (SHIMADZU) 01GC with Liquid Injectors (AGILENT) 01UV Spectro Photometer (LAB INDIA) 01

MR Apparatus (POLMON) 01TDS/Conductivity Meter (POLMON) 01

pH Merer (LAB INDIA) 01

KF Titrator (POLMON) 01

IR Moisture Analyzer (LCGC) 01

List of Major Analytical Instruments (UNIT 1)

QUALITY CONTROL (UNIT 2)

WET LAB

HPLC LAB

CONTROL SAMPLE ROOM

GC LAB

Name of the Instrument No.s

HPLC with VWD detector (AGILENT) 01

HPLC with VWD detector (SHIMADZU) 02HPLC with RI detector (SHIMADZU) 01GC with HEAD SPACE (SHIMADZU) 01GC with Liquid Injectors (AGILENT) 01UV Spectro Photometer (LAB INDIA) 01

MR Apparatus (POLMON) 01TDS/Conductivity Meter (POLMON) 01

List of Major Analytical Instruments (UNIT 2)

SPECIFICATIONS

Raw materialsv All raw materials used in the manufacturing process are tested as per pre-

defined & well established specifications and approved by QC.

v No raw materials are used in the process without approval from the Quality Control department.

Intermediate & Finished product

v Intermediates are tested and approved by QC as per release specifications.

v Finished products are released to market by QA.

Name of the Instrument UNIT 1 UNIT 2BRINE Compressor 18 TR – 2 No's &

20 TR – 1 No.14 TR -1 No. & 18

TR - 1No. & 20 TR - 1No.

BOILER 0.8 MT & 2.0 MT 2.0 MT

DG SET 125 KVA & 250 KVA 125 KVA & 250 KVA

List of Major Utilities

QUALITY MANAGEMENTv Documentation and Record controlsv Review and approval of QMS procedures and documentsv Validationsv Change control Managementv Vendor approval and evaluationv Testing of Raw materials, Intermediates and Finished productsv Product Releasev Handling of OOS and Deviationsv Handling of customer complaints, product recalls and returnsv Internal Auditsv Stability Studiesv Trainingv Annual Product (Quality) Reviews (AQRs)

RESEARCH & DEVELOPMENT

Fully Integrated & Qualified R&D Team of 11 Scientists v Process Development of Intermediates & API’Sv Characterization and Synthesizing of ImpuritiesKey Initiatives of On site R&D team v Cost Reduction & Quality Improvementv Technology Transfer from R&D to Plant (Scale up &

Validations)v Troubleshootingv Customer support

REACTION CAPABILITIES• Grignard reactions • Hydrogenation • Alkylation reactions• Halogenations reactions.• Oxidation reactions • Reduction reactions • Esterification reactions • Hydrolysis reactions • Condensation reactions• De-hydrogination reactions.• Allylic bromination reactions • Cyclization reactions• Cryogenic reactions

ENVIRONMENT MANAGEMENT (UNIT 1)

v Segregation of Effluentv High TDS and Low TDS

v Multiple Effect Evaporation System:v Capacity: 20 KL/day

v Solid waste: v Solid waste will be sent to State Approved Solid Waste disposal

Facility.

v Scrubbing systems:v Scrubbing systems are in place to ensure acidic vapors do not enter

into atmosphere.

ENVIRONMENT MANAGEMENT (UNIT 2)

v Segregation of Effluentv High TDS and Low TDS

v Solid waste: v Solid waste will be sent to State Approved Solid Waste disposal

Facility.

v Scrubbing systems:v Scrubbing systems are in place to ensure acidic vapors do not enter

into atmosphere.

THANK YOU