2005

Pyrazine derivativesR 0550 A Novel and Facile Method to Synthesize (R)- and (S)-2-Methylpiperazine. —

The key step in the synthesis of the title compound (R)-(VIII) is the construction of the six-membered ring (VI). (S)-(VIII) is prepared analogously starting from (S)-(I). — (LIU, B.; XU, G.-Y.; YANG, C.-H.; WU*, X.-H.; XIE, Y.-Y.; Synth. Commun. 34 (2004) 22, 4111-4118; State Key Lab. Drug Res., Shanghai Inst. Mater. Med., Chin. Acad. Sci., Shanghai 200031, Peop. Rep. China; Eng.) — K. Woydowski

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