A karyotype DAS clientDAS workshop 2009

10th March

Rafael Jimenez

Visualization of genome data in combination with experimental data and genome analysis helps to formulate testable hypothesis.

Eukaryotic Genome browsers specialized to represent annotations on ...

Specific chromosomes Genome regions in one chromosome Detailed views on genome regions

Eukaryotic genome analysis requires visualization in a higher representation level ...

Full genomic context -> Karyotype

Introduction

Karyotype DAS client

DAS web browser to visualize Eukaryotic genome data at the level of karyotype, chromosome and cytoband. Still a prototype!

For more detail views in a lower representation level it interacts with the Ensembl web browser.

Karyotype Chromosome Genome region Detailed view

Karyotype DAS viewer Ensembl

Implementation

Servicebroker

Serviceconsumer

Serviceprovider

ServiceContract......

Interact

PublishFind

Service Oriented Architecture

Registry

Client Sources

DAS.........

PublishFind

Distributed Annotation System

Implementation

Interact

DASRegistry

GenomeAnalysis

KaryotypeDAS Client

CromosomeTypeEnsembl

Gene ExpressionProfile Analysis Suite

GPAS

Provide

1

1

Karyotype

Chromosome

Genome region Qualitative

Quantitative (score)

+/-sourcesby view

2 3

2.1

2.2

2.3

2.4

2.5

3.1binning:maxbins

3.2

3.3

4

Thank you!

Thanks for its support to …

Thanks to our collaborators …

UCTSouth Africa

CBIO, UCTSouth Africa

… especially for his contribution on this project to …

Joaquin Tarraga

QuickTime™ and a decompressor

are needed to see this picture.

Bioinfomatics department