Upload
jin-ha-lee
View
225
Download
1
Embed Size (px)
Citation preview
2007
Benzimidazole derivativesR 0200 A Facile Synthesis of 2-Acyl and 2-Alkylaminobenzimidazoles for 5-Lipoxygenase
Inhibitors. — A variety of substituted 2-aminobenzimidazoles is prepared from o-phe-nylenediamines and tested as 5-lipoxygenase inhibitors. Several acylaminobenzimida-zoles such as (IIIa)—(IIIf) show good leukotriene inhibition activity. — (LEE, J. H.; AN, M. H.; CHOI, E. H.; CHOO, H.-Y. P.; HAN*, G.; Heterocycles 70 (2006) 1, 571-580; Dep. Biotechnol., Coll. Eng., Yonsei Univ., Seoul 120-749, S. Korea; Eng.) — R. Staver
23- 117